PMIDs of Cochrane reviews (Latest versions only) Title Times appeared in search results Times cited in Wikipedia Latest version? (1=Yes, 0=No)
index
Total N/A N/A 14965 1001 6767
2562 28702956 Interventions for treating lymphocytic colitis. 6 2 1
929 19821271 Psychological treatments for bulimia nervosa and binging. 3 2 1
3667 29943802 Influenza vaccine for chronic obstructive pulmonary disease (COPD). 3 2 1
4688 25569281 Exercise for osteoarthritis of the knee. 3 2 1
3043 24453068 Endovascular repair of abdominal aortic aneurysm. 4 2 1
931 16856036 Self-help and guided self-help for eating disorders. 4 2 1
5611 20091514 Caffeine for asthma. 2 2 1
4967 27763732 Antibiotics for ventilator-associated pneumonia. 2 2 1
2100 22161438 Flossing for the management of periodontal diseases and dental caries in adults. 3 2 1
3744 23450529 Vaccines for preventing influenza in people with asthma. 3 2 1
1992 25526608 Interventions for melanoma in situ, including lentigo maligna. 3 2 1
4689 29664187 Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review. 2 2 1
1926 17943794 Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. 4 2 1
4466 26241698 Post-pyloric versus gastric tube feeding for preventing pneumonia and improving nutritional outcomes in critically ill adults. 2 2 1
590 27063583 Omega-3 fatty acids for the treatment of dementia. 5 2 1
852 26222376 Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease. 2 2 1
2975 28922695 Strategies for detecting colon cancer in patients with inflammatory bowel disease. 8 2 1
3403 26493180 Laser treatment of drusen to prevent progression to advanced age-related macular degeneration. 3 2 1
2804 20927726 Grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children. 2 2 1
1917 22161394 Interferon alpha for chronic hepatitis D. 7 2 1
1658 22895928 Ivermectin for onchocercal eye disease (river blindness). 8 2 1
3947 26824399 Surgical versus non-surgical treatment for lumbar spinal stenosis. 3 2 1
1284 28891588 Ursodeoxycholic acid for cystic fibrosis-related liver disease. 3 2 1
1033 18254088 Intravitreal steroids for macular edema in diabetes. 4 2 1
1639 23633341 Temozolomide for high grade glioma. 2 2 1
4323 25490118 Calcimimetics for secondary hyperparathyroidism in chronic kidney disease patients. 5 2 1
3188 22972085 Systemic interventions for recurrent aphthous stomatitis (mouth ulcers). 2 2 1
3677 27644166 Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease. 3 2 1
4696 27103611 Topical NSAIDs for chronic musculoskeletal pain in adults. 2 2 1
612 25004278 Statins for the treatment of dementia. 3 2 1
2540 20166079 Vena caval filters for the prevention of pulmonary embolism. 2 2 1
5482 27245310 Speech and language therapy for aphasia following stroke. 2 2 1
707 26490760 Intra-articular corticosteroid for knee osteoarthritis. 3 2 1
2278 24170669 Blood pressure targets for hypertension in people with diabetes mellitus. 3 2 1
4698 19821296 Transcutaneous electrostimulation for osteoarthritis of the knee. 2 2 1
3624 25090020 Topical antifungal treatments for tinea cruris and tinea corporis. 3 2 1
1525 26270746 Music for insomnia in adults. 2 2 1
3622 23076898 Oral treatments for fungal infections of the skin of the foot. 2 2 1
3621 25191970 Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment. 2 2 1
712 16235295 Low level laser therapy (Classes I, II and III) for treating rheumatoid arthritis. 2 2 1
4692 25503775 Osteotomy for treating knee osteoarthritis. 2 2 1
100 28304084 Surgical versus non-surgical management for pleural empyema. 2 1 1
3755 27428009 Cannabinoids for fibromyalgia. 1 1 1
3913 28639319 Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years. 2 1 1
2188 19160184 Vaccines for preventing tick-borne encephalitis. 5 1 1
2251 27096438 Sumatriptan plus naproxen for the treatment of acute migraine attacks in adults. 1 1 1
3911 29543316 Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. 1 1 1
1910 16625613 Hepatitis B immunisation for newborn infants of hepatitis B surface antigen-positive mothers. 2 1 1
176 24610050 Endometriosis: an overview of Cochrane Reviews. 1 1 1
241 27087121 Insulin and oral agents for managing cystic fibrosis-related diabetes. 3 1 1
102 26121003 CHIVA method for the treatment of chronic venous insufficiency. 2 1 1
391 28218802 Non-invasive ventilation for cystic fibrosis. 3 1 1
239 26968204 Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults. 10 1 1
2132 25269391 Prophylaxis for Pneumocystis pneumonia (PCP) in non-HIV immunocompromised patients. 6 1 1
2192 10796565 Vaccines for preventing plague. 1 1 1
6681 24338431 Electromagnetic fields for treating osteoarthritis. 1 1 1
2156 21069689 Radical prostatectomy versus watchful waiting for prostate cancer. 1 1 1
4899 17253567 Probiotics for preventing preterm labour. 1 1 1
6476 22895954 Pharmacotherapy for mild hypertension. 1 1 1
3877 17054131 Portosystemic shunts versus endoscopic therapy for variceal rebleeding in patients with cirrhosis. 2 1 1
4919 25485940 The Epley (canalith repositioning) manoeuvre for benign paroxysmal positional vertigo. 1 1 1
286 27788565 Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy. 5 1 1
3477 23076888 Surgery or embolization for varicoceles in subfertile men. 1 1 1
287 29932206 Saline irrigation for allergic rhinitis. 2 1 1
1912 28188612 Hepatitis B immunoglobulin during pregnancy for prevention of mother-to-child transmission of hepatitis B virus. 2 1 1
6652 26106870 Hyperbaric oxygen therapy for chronic wounds. 2 1 1
5101 25220133 Systemic safety of bevacizumab versus ranibizumab for neovascular age-related macular degeneration. 1 1 1
6677 25629804 Chondroitin for osteoarthritis. 1 1 1
3353 29553157 Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease. 3 1 1
1913 25385500 Hepatitis B vaccination during pregnancy for preventing infant infection. 5 1 1
1914 15266500 Hepatitis B vaccination for patients with chronic renal failure. 2 1 1
1901 28922704 Direct-acting antivirals for chronic hepatitis C. 9 1 1
2257 23797677 Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults. 1 1 1
406 28881006 Simple aspiration versus intercostal tube drainage for primary spontaneous pneumothorax in adults. 1 1 1
3921 17943900 Cholecystectomy deferral in patients with endoscopic sphincterotomy. 2 1 1
237 27071857 Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta-analysis. 2 1 1
91 16034908 Vitamin A for non-measles pneumonia in children. 2 1 1
2187 23235648 Drugs for treating giardiasis. 1 1 1
6682 28141914 Exercise for hand osteoarthritis. 1 1 1
3708 27886372 Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy. 2 1 1
3358 11034769 Fluoride for treating postmenopausal osteoporosis. 1 1 1
3357 21735380 Exercise for preventing and treating osteoporosis in postmenopausal women. 1 1 1
179 21154398 Gonadotrophin-releasing hormone analogues for pain associated with endometriosis. 2 1 1
3355 18254018 Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women. 1 1 1
2071 15846643 Alarm interventions for nocturnal enuresis in children. 1 1 1
6620 25922861 Antibiotic regimens for postpartum endometritis. 1 1 1
6412 27819746 Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child. 1 1 1
4873 12519556 Interventions for toxic epidermal necrolysis. 1 1 1
2191 23235610 Interventions for actinic keratoses. 6 1 1
95 28631310 Zinc supplementation for the treatment of measles in children. 1 1 1
6423 18646083 Psychological treatments for epilepsy. 1 1 1
2045 23450601 Magnesium sulphate for women at term for neuroprotection of the fetus. 3 1 1
1909 22786522 Hepatitis A immunisation in persons not previously exposed to hepatitis A. 2 1 1
3526 17443546 Granulocyte-colony stimulating factor (G-CSF) as an adjunct to antibiotics in the treatment of pneumonia in adults. 2 1 1
3753 27251337 Antipsychotics for fibromyalgia in adults. 2 1 1
3378 24729336 Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men. 1 1 1
5102 25919144 Interventions for rosacea. 1 1 1
3839 29676439 Oral and sublingual immunotherapy for egg allergy. 3 1 1
2203 23633350 Aspirin with or without an antiemetic for acute migraine headaches in adults. 1 1 1
3729 16235359 Short-term ambulatory oxygen for chronic obstructive pulmonary disease. 1 1 1
1983 25710794 Interventions for vitiligo. 2 1 1
3738 26391969 Tiotropium versus ipratropium bromide for chronic obstructive pulmonary disease. 1 1 1
4963 18425892 Interventions for treating collagenous colitis. 2 1 1
153 20927774 Multidisciplinary care for Guillain-Barré syndrome. 13 1 1
152 25238327 Intravenous immunoglobulin for Guillain-Barré syndrome. 13 1 1
6533 16235338 Art therapy for schizophrenia or schizophrenia-like illnesses. 1 1 1
3736 21735417 Telehealthcare for chronic obstructive pulmonary disease. 1 1 1
1981 12535506 Valproate for acute mood episodes in bipolar disorder. 1 1 1
3735 27272131 Tai Chi for chronic obstructive pulmonary disease (COPD). 2 1 1
3568 25575340 Indacaterol, a once-daily beta2-agonist, versus twice-daily beta₂-agonists or placebo for chronic obstructive pulmonary disease. 2 1 1
1970 18425912 Omega-3 fatty acids for bipolar disorder. 2 1 1
1969 19160237 Olanzapine in long-term treatment for bipolar disorder. 1 1 1
5109 21154340 Family intervention for schizophrenia. 2 1 1
3419 27209627 Antiepileptic drugs for the primary and secondary prevention of seizures in viral encephalitis. 2 1 1
5125 25835432 Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection. 2 1 1
125 26132597 Topical tacrolimus for atopic dermatitis. 6 1 1
124 17943859 Topical pimecrolimus for eczema. 2 1 1
3719 27930803 Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease. 2 1 1
2225 26709672 Normobaric and hyperbaric oxygen therapy for the treatment and prevention of migraine and cluster headache. 2 1 1
3868 29762873 L-ornithine L-aspartate for prevention and treatment of hepatic encephalopathy in people with cirrhosis. 3 1 1
3423 17636750 Vaccines for preventing Japanese encephalitis. 2 1 1
3422 24954057 Vaccines for post-exposure prophylaxis against varicella (chickenpox) in children and adults. 2 1 1
6557 17253555 Drama therapy for schizophrenia or schizophrenia-like illnesses. 1 1 1
2227 23633349 Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. 1 1 1
6486 26537796 Omega-3 fatty acids for depression in adults. 1 1 1
1980 16437453 Topiramate for acute affective episodes in bipolar disorder. 2 1 1
6547 30480760 Cognitive behavioural therapy plus standard care versus standard care plus other psychosocial treatments for people with schizophrenia. 1 1 1
5097 25856365 Omega 3 fatty acids for preventing or slowing the progression of age-related macular degeneration. 1 1 1
3481 26857947 Aflibercept for neovascular age-related macular degeneration. 3 1 1
3814 23784858 Intranasal ipratropium bromide for the common cold. 2 1 1
3734 25178099 Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. 1 1 1
2058 15106204 Speech and language therapy to improve the communication skills of children with cerebral palsy. 1 1 1
139 22895927 Minocycline for acne vulgaris: efficacy and safety. 2 1 1
138 27670126 Light therapies for acne. 1 1 1
2142 18425978 Five-alpha-reductase Inhibitors for prostate cancer prevention. 5 1 1
3725 28777450 Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease. 2 1 1
92 16235283 Vitamin A for treating measles in children. 2 1 1
2206 23633360 Diclofenac with or without an antiemetic for acute migraine headaches in adults. 1 1 1
135 27038134 Interventions for acne scars. 1 1 1
4971 27778318 Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia. 2 1 1
3732 27545342 Smoking cessation for people with chronic obstructive pulmonary disease. 2 1 1
1991 23775773 Interferon alpha for the adjuvant treatment of cutaneous melanoma. 2 1 1
3746 28636204 Aerobic exercise training for adults with fibromyalgia. 2 1 1
6478 18254065 Relaxation therapies for the management of primary hypertension in adults. 1 1 1
3466 28567798 Management for intussusception in children. 1 1 1
2196 27351677 Acupuncture for the prevention of episodic migraine. 1 1 1
3742 27846347 Upper limb exercise training for COPD. 1 1 1
3741 28631387 Umeclidinium bromide versus placebo for people with chronic obstructive pulmonary disease (COPD). 2 1 1
273 20614452 Antihistamines used in addition to topical nasal steroids for intermittent and persistent allergic rhinitis in children. 4 1 1
3740 25046211 Tiotropium versus placebo for chronic obstructive pulmonary disease. 1 1 1
5096 17636773 Laser photocoagulation for neovascular age-related macular degeneration. 2 1 1
275 26171907 Capsaicin for non-allergic rhinitis. 2 1 1
276 25347280 Decongestants, antihistamines and nasal irrigation for acute sinusitis in children. 3 1 1
3758 24018611 Cognitive behavioural therapies for fibromyalgia. 1 1 1
357 23235645 Chemical pleurodesis versus surgical intervention for persistent and recurrent pneumothoraces in cystic fibrosis. 2 1 1
3494 16034881 Metformin monotherapy for type 2 diabetes mellitus. 5 1 1
1545 28982219 Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease. 6 1 1
4331 19160295 Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer. 2 1 1
4333 25086573 Oral antiviral therapy for prevention of genital herpes outbreaks in immunocompetent and nonpregnant patients. 2 1 1
5460 25207925 Anticonvulsant therapy for status epilepticus. 1 1 1
4335 18254066 Third trimester antiviral prophylaxis for preventing maternal genital herpes simplex virus (HSV) recurrences and neonatal infection. 3 1 1
1541 21249659 Enteral tube feeding for amyotrophic lateral sclerosis/motor neuron disease. 3 1 1
4340 23235671 Amitriptyline versus placebo for major depressive disorder. 3 1 1
2884 26028608 Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis. 2 1 1
1537 27822919 Cell-based therapies for amyotrophic lateral sclerosis/motor neuron disease. 4 1 1
4630 23728646 Non-steroidal anti-inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults. 1 1 1
4344 29083100 Mefloquine for preventing malaria during travel to endemic areas. 3 1 1
4346 27158764 Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis. 4 1 1
1534 29985545 Interventions for recurrent corneal erosions. 2 1 1
1532 25055058 Deep anterior lamellar keratoplasty versus penetrating keratoplasty for treating keratoconus. 3 1 1
1531 26867004 Conjunctival autograft for pterygium. 4 1 1
1528 22696365 Photorefractive keratectomy (PRK) versus laser assisted in situ keratomileusis (LASIK) for hyperopia correction. 2 1 1
1527 29388195 Vaccines for preventing influenza in healthy children. 4 1 1
5470 17943862 Occlusal splints for treating sleep bruxism (tooth grinding). 1 1 1
4356 26120804 Nonsteroidal anti-inflammatory drugs (NSAIDs) and non-opioids for acute renal colic. 2 1 1
5849 16235402 Psychosocial interventions for conversion disorder. 1 1 1
5848 24122674 Thymectomy for non-thymomatous myasthenia gravis. 1 1 1
5846 25515947 Ephedrine for myasthenia gravis, neonatal myasthenia and the congenital myasthenic syndromes. 1 1 1
5844 25310725 Acetylcholinesterase inhibitor treatment for myasthenia gravis. 1 1 1
1521 30484855 Laparoscopic versus open surgery for suspected appendicitis. 2 1 1
2545 25099517 Drugs for treating urinary schistosomiasis. 1 1 1
1517 22071846 Appendectomy versus antibiotic treatment for acute appendicitis. 1 1 1
5879 16437532 Cholinesterase inhibitors for Alzheimer's disease. 1 1 1
2528 25518837 Statins for primary prevention of venous thromboembolism. 2 1 1
6684 24756895 Exercise for osteoarthritis of the hip. 1 1 1
5836 16437487 Psychological interventions for multiple sclerosis. 1 1 1
1503 23733381 Antibiotics for the common cold and acute purulent rhinitis. 2 1 1
4382 28513067 Interventions for cutaneous molluscum contagiosum. 3 1 1
4383 25485740 Endoscopic pneumatic dilation versus botulinum toxin injection in the management of primary achalasia. 1 1 1
5815 14974004 Hyperbaric oxygen therapy for multiple sclerosis. 1 1 1
2555 25933684 Topical antifungals for seborrhoeic dermatitis. 2 1 1
5813 15674920 Exercise therapy for multiple sclerosis. 1 1 1
5811 23235605 Dietary interventions for multiple sclerosis. 1 1 1
4326 27150433 Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure. 1 1 1
4388 20464733 Glatiramer acetate for multiple sclerosis. 2 1 1
5491 27251461 Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions. 1 1 1
2558 23235637 Local interventions for the management of alveolar osteitis (dry socket). 4 1 1
2559 27578151 Surgical removal versus retention for the management of asymptomatic disease-free impacted wisdom teeth. 9 1 1
5804 27082500 Alemtuzumab for multiple sclerosis. 2 1 1
4392 30687936 Pharmacotherapies for cannabis dependence. 1 1 1
2560 25069437 Surgical techniques for the removal of mandibular wisdom teeth. 5 1 1
2830 24974096 Zinc supplements for preventing otitis media. 2 1 1
2829 27486835 Xylitol for preventing acute otitis media in children up to 12 years of age. 1 1 1
4395 29236286 Corticosteroids for pneumonia. 3 1 1
1493 23440795 Statins for the primary prevention of cardiovascular disease. 1 1 1
1152 24259251 Post-operative radiotherapy for ductal carcinoma in situ of the breast. 4 1 1
1153 23076938 Postoperative tamoxifen for ductal carcinoma in situ. 7 1 1
2824 16437533 Systemic antibiotics versus topical treatments for chronically discharging ears with underlying eardrum perforations. 1 1 1
5832 23235634 Oral versus intravenous steroids for treatment of relapses in multiple sclerosis. 1 1 1
5479 19370685 Thalidomide and thalidomide analogues for maintenance of remission in Crohn's disease. 1 1 1
4369 25882271 Anticonvulsants for cocaine dependence. 1 1 1
1516 16034862 Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. 2 1 1
4017 25126773 Magnesium sulphate for preventing preterm birth in threatened preterm labour. 1 1 1
2658 18646170 Corticosteroids as adjuvant to antiviral treatment in Ramsay Hunt syndrome (herpes zoster oticus with facial palsy) in adults. 1 1 1
5025 20614421 Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. 1 1 1
346 27666123 Lasers for caries removal in deciduous and permanent teeth. 2 1 1
250 25212112 Cardiopulmonary resuscitation (CPR) plus delayed defibrillation versus immediate defibrillation for out-of-hospital cardiac arrest. 3 1 1
1999 16235336 Statins and fibrates for preventing melanoma. 1 1 1
6473 26934541 Long-term effects of weight-reducing diets in people with hypertension. 1 1 1
6472 20238338 Interventions used to improve control of blood pressure in patients with hypertension. 1 1 1
3717 30376188 Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). 3 1 1
118 26197477 Maternal prenatal and/or postnatal n-3 long chain polyunsaturated fatty acids (LCPUFA) supplementation for preventing allergies in early childhood. 6 1 1
6667 26337865 Systemic antibiotics for treating diabetic foot infections. 1 1 1
4896 27696372 Antibiotic treatment for the sexual partners of women with bacterial vaginosis. 1 1 1
3487 22972104 Cinnamon for diabetes mellitus. 6 1 1
3715 28116747 Pneumococcal vaccines for preventing pneumonia in chronic obstructive pulmonary disease. 4 1 1
2000 27455163 Sun protection for preventing basal cell and squamous cell skin cancers. 5 1 1
4976 26266942 Silver-coated endotracheal tubes for prevention of ventilator-associated pneumonia in critically ill patients. 2 1 1
3884 17054221 TIPS versus paracentesis for cirrhotic patients with refractory ascites. 2 1 1
115 25598014 House dust mite reduction and avoidance measures for treating eczema. 4 1 1
3885 23235576 Ursodeoxycholic acid for primary biliary cirrhosis. 4 1 1
6465 26126003 Calcium supplementation for prevention of primary hypertension. 2 1 1
122 26871981 Specific allergen immunotherapy for the treatment of atopic eczema. 4 1 1
358 25519778 Conservative versus interventional management for primary spontaneous pneumothorax in adults. 1 1 1
5143 26798030 Subcutaneous rapid-acting insulin analogues for diabetic ketoacidosis. 1 1 1
5144 20927731 Interventions for bullous pemphigoid. 2 1 1
6442 28982217 Yoga for epilepsy. 1 1 1
6676 25773267 Braces and orthoses for treating osteoarthritis of the knee. 1 1 1
3705 22071841 Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease. 1 1 1
6685 26475434 Hyaluronic acid and other conservative treatment options for osteoarthritis of the ankle. 1 1 1
167 22592712 Chinese herbal medicine for endometriosis. 2 1 1
3486 25637717 Blood pressure control for diabetic retinopathy. 3 1 1
105 25075589 Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus open surgery for great saphenous vein varices. 1 1 1
3390 15846612 Corticosteroids for pulmonary sarcoidosis. 1 1 1
6673 20091527 Acupuncture for peripheral joint osteoarthritis. 1 1 1
6629 25327508 Prophylactic antibiotics for manual removal of retained placenta in vaginal birth. 1 1 1
3397 28756618 Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. 3 1 1
3396 28756617 Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. 3 1 1
6672 29729027 Acupuncture for hip osteoarthritis. 1 1 1
109 17054141 Injection sclerotherapy for varicose veins. 1 1 1
5148 18254008 Physiotherapy interventions for ankylosing spondylitis. 2 1 1
6454 19821398 Blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertension. 1 1 1
3893 26787125 Brief school-based interventions and behavioural outcomes for substance-using adolescents. 2 1 1
5149 25427435 Sulfasalazine for ankylosing spondylitis. 2 1 1
4890 22161401 Physical therapy for Bell's palsy (idiopathic facial paralysis). 2 1 1
112 15495134 Surgery versus sclerotherapy for the treatment of varicose veins. 1 1 1
3589 24353107 Water-based exercise training for chronic obstructive pulmonary disease. 2 1 1
3388 22972049 Antibiotics versus placebo for acute bacterial conjunctivitis. 1 1 1
4888 27428352 Corticosteroids for Bell's palsy (idiopathic facial paralysis). 2 1 1
6674 27007113 Aquatic exercise for the treatment of knee and hip osteoarthritis. 1 1 1
4887 26559436 Antiviral treatment for Bell's palsy (idiopathic facial paralysis). 2 1 1
2001 19821334 Surgical excision margins for primary cutaneous melanoma. 2 1 1
3385 17636630 Interventions for treating scabies. 1 1 1
3713 28922692 Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease. 4 1 1
3384 24566946 Interventions for preventing the spread of infestation in close contacts of people with scabies. 1 1 1
2002 29405038 Systemic treatments for metastatic cutaneous melanoma. 3 1 1
4886 20687071 Acupuncture for Bell's palsy. 2 1 1
3809 22513962 Modifications of the Epley (canalith repositioning) manoeuvre for posterior canal benign paroxysmal positional vertigo (BPPV). 2 1 1
1967 26415966 Ketamine and other glutamate receptor modulators for depression in bipolar disorder in adults. 1 1 1
3720 25705944 Pulmonary rehabilitation for chronic obstructive pulmonary disease. 1 1 1
6484 25470301 Interventions to improve return to work in depressed people. 1 1 1
3539 19821273 Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients. 2 1 1
1883 24307460 Antiviral interventions for liver transplant patients with recurrent graft infection due to hepatitis C virus. 2 1 1
3336 23835682 Strength training and aerobic exercise training for muscle disease. 7 1 1
3940 27123955 Hyperbaric oxygen therapy for late radiation tissue injury. 2 1 1
6698 19821403 S-Adenosylmethionine for osteoarthritis of the knee or hip. 1 1 1
2012 28786098 Antenatal and intrapartum interventions for preventing cerebral palsy: an overview of Cochrane systematic reviews. 3 1 1
3795 19160220 Interventions for haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura. 4 1 1
224 20091520 Surgery for cervical radiculopathy or myelopathy. 3 1 1
3944 23996271 Nonoperative treatment for lumbar spinal stenosis with neurogenic claudication. 3 1 1
6701 20927773 Surgery for shoulder osteoarthritis. 1 1 1
71 23450537 Treatment of Lennox-Gastaut syndrome. 14 1 1
3697 24823712 Non-invasive ventilation during exercise training for people with chronic obstructive pulmonary disease. 1 1 1
6382 17054255 Stapled versus conventional surgery for hemorrhoids. 1 1 1
6381 25117413 Interventions for congenital talipes equinovarus (clubfoot). 1 1 1
484 28670710 Non-steroidal anti-inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery. 3 1 1
450 17253497 Interventions for preventing oral candidiasis for patients with cancer receiving treatment. 2 1 1
3949 22696337 Surgical removal versus retention for the management of asymptomatic impacted wisdom teeth. 2 1 1
6377 27150280 Vitamin supplementation for preventing miscarriage. 1 1 1
1885 24297303 Antiviral prophylaxis for the prevention of chronic hepatitis C virus in patients undergoing liver transplantation. 2 1 1
76 23543555 Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and psychological symptoms in older people with dementia. 2 1 1
2080 23235592 Treatment for lupus nephritis. 6 1 1
6697 15654705 Rofecoxib for osteoarthritis. 1 1 1
420 18254022 Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps. 4 1 1
4981 15846704 Vitamins for epilepsy. 3 1 1
3759 29457627 Combination pharmacotherapy for the treatment of fibromyalgia in adults. 1 1 1
6404 26859528 Ketogenic diet and other dietary treatments for epilepsy. 1 1 1
437 27572944 Effect of restricted pacifier use in breastfeeding term infants for increasing duration of breastfeeding. 6 1 1
436 22972099 Combined corticosteroid and long-acting beta(2)-agonist in one inhaler versus long-acting beta(2)-agonists for chronic obstructive pulmonary disease. 2 1 1
3673 24615270 Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. 2 1 1
4863 17253470 Nasal decongestants for the common cold. 2 1 1
2096 30277579 Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems. 5 1 1
5009 22592706 Interventions for chronic blepharitis. 2 1 1
6747 25918919 Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures. 1 1 1
3670 22161409 Inhaled corticosteroids versus long-acting beta(2)-agonists for chronic obstructive pulmonary disease. 1 1 1
528 19370677 Cannabinoids for the treatment of dementia. 4 1 1
3997 25356860 Eculizumab for treating patients with paroxysmal nocturnal hemoglobinuria. 7 1 1
531 22419314 Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease. 4 1 1
6312 26089258 Stopping long-acting beta2-agonists (LABA) for adults with asthma well controlled by LABA and inhaled corticosteroids. 1 1 1
2164 21412903 Celiac plexus block for pancreatic cancer pain in adults. 2 1 1
3778 27684492 Pregabalin for pain in fibromyalgia in adults. 1 1 1
543 19160328 Donepezil for dementia in people with Down syndrome. 3 1 1
536 22336813 Cognitive stimulation to improve cognitive functioning in people with dementia. 1 1 1
2168 27383694 Diagnostic accuracy of laparoscopy following computed tomography (CT) scanning for assessing the resectability with curative intent in pancreatic and periampullary cancer. 3 1 1
6751 26362566 Corticosteroids for acute bacterial meningitis. 1 1 1
6754 27813057 Fluid therapy for acute bacterial meningitis. 1 1 1
204 26086959 Braces for idiopathic scoliosis in adolescents. 1 1 1
2102 26075879 Fluoride gels for preventing dental caries in children and adolescents. 1 1 1
4823 25321340 Topical corticosteroids as adjunctive therapy for bacterial keratitis. 1 1 1
5231 22258953 Interventions for impetigo. 2 1 1
6757 29405037 Osmotic therapies added to antibiotics for acute bacterial meningitis. 1 1 1
542 29923184 Donepezil for dementia due to Alzheimer's disease. 3 1 1
1858 26333288 Support surfaces for pressure ulcer prevention. 1 1 1
6730 20464750 Chemotherapy and supportive care versus supportive care alone for advanced non-small cell lung cancer. 1 1 1
3684 24671923 Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis. 1 1 1
3936 23803963 Immunomodulatory interventions for focal epilepsy syndromes. 4 1 1
6691 15266461 Low level laser therapy (Classes I, II and III) for treating osteoarthritis. 1 1 1
2041 29063594 Late (> 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants. 5 1 1
5174 27225981 Interventions for female pattern hair loss. 2 1 1
6692 24848732 Oral herbal therapies for treating osteoarthritis. 1 1 1
3617 24801225 Acupuncture for epilepsy. 2 1 1
2085 25177840 Interleukin-1 inhibitors for acute gout. 1 1 1
2086 25330136 Interventions for tophi in gout. 1 1 1
1863 21678338 Scopolamine (hyoscine) for preventing and treating motion sickness. 1 1 1
3509 26482542 Chemotherapy for advanced non-small cell lung cancer in the elderly population. 6 1 1
1861 23543538 Wound cleansing for pressure ulcers. 1 1 1
2087 24186771 Lifestyle interventions for acute gout. 1 1 1
3307 10796740 Beta-sitosterols for benign prostatic hyperplasia. 2 1 1
6722 20464738 Aerobic exercise training programmes for improving physical and psychosocial health in adults with Down syndrome. 1 1 1
482 26866343 Corticosteroid implants for chronic non-infectious uveitis. 3 1 1
4954 28597471 Gabapentin for chronic neuropathic pain in adults. 1 1 1
3685 28185242 Long-acting muscarinic antagonist (LAMA) plus long-acting beta-agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive pulmonary disease (COPD). 2 1 1
2083 25123076 Colchicine for acute gout. 1 1 1
3613 18677777 Antioxidant supplements for preventing gastrointestinal cancers. 1 1 1
4852 22972087 Acupuncture for insomnia. 1 1 1
3792 25348498 Prenatal versus postnatal repair procedures for spina bifida for improving infant and maternal outcomes. 5 1 1
458 29168557 Probiotics for vulvovaginal candidiasis in non-pregnant women. 3 1 1
6374 30081430 Progestogen for treating threatened miscarriage. 1 1 1
6373 24173668 Progestogen for preventing miscarriage. 1 1 1
67 16437455 The effectiveness of atypical antipsychotics for the treatment of aggression and psychosis in Alzheimer's disease. 2 1 1
2081 22895983 Music education for improving reading skills in children and adolescents with dyslexia. 2 1 1
2283 16235327 Cardioselective beta-blockers for chronic obstructive pulmonary disease. 3 1 1
3763 17943797 Exercise for treating fibromyalgia syndrome. 1 1 1
463 24459050 Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma. 3 1 1
6707 20091539 Therapeutic ultrasound for osteoarthritis of the knee or hip. 1 1 1
6358 17636722 Thyroid hormone replacement for subclinical hypothyroidism. 1 1 1
3312 11869585 Pygeum africanum for benign prostatic hyperplasia. 2 1 1
3689 27739074 Lung volume reduction surgery for diffuse emphysema. 1 1 1
2183 26301604 Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults. 2 1 1
6402 27933615 Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy. 1 1 1
232 25957940 Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders. 7 1 1
3701 23235577 Nutritional supplementation for stable chronic obstructive pulmonary disease. 1 1 1
4956 28085183 Topical capsaicin (high concentration) for chronic neuropathic pain in adults. 1 1 1
2009 18646067 Cognitive behaviour therapy for chronic fatigue syndrome in adults. 1 1 1
5080 27258214 Systematic screening for the detection of atrial fibrillation. 1 1 1
229 23807762 Chemotherapy for second-stage human African trypanosomiasis. 2 1 1
429 20393943 Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma. 4 1 1
1887 20091566 Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus. 4 1 1
79 23943263 Antibiotics for preventing complications in children with measles. 6 1 1
3342 27706804 Bisphosphonates for steroid-induced osteoporosis. 2 1 1
3797 20091645 Topical fluoride as a cause of dental fluorosis in children. 1 1 1
2084 25287939 Dietary supplements for chronic gout. 2 1 1
455 12519623 Nonoxynol-9 for preventing vaginal acquisition of sexually transmitted infections by women from men. 3 1 1
449 22336835 Interventions for erosive lichen planus affecting mucosal sites. 5 1 1
2277 28107561 Beta-blockers for hypertension. 2 1 1
5195 23152278 Oral immunotherapy for milk allergy. 2 1 1
6709 14584019 Thermotherapy for treatment of osteoarthritis. 1 1 1
6710 16856101 Tramadol for osteoarthritis. 1 1 1
3313 23235581 Serenoa repens for benign prostatic hyperplasia. 2 1 1
6360 22592730 Chinese herbal medicines for threatened miscarriage. 1 1 1
6375 20824830 Surgical procedures for evacuating incomplete miscarriage. 1 1 1
6712 26002823 Antibiotics for acute laryngitis in adults. 1 1 1
3691 12804425 Methylxanthines for exacerbations of chronic obstructive pulmonary disease. 1 1 1
534 22071821 Cognitive reframing for carers of people with dementia. 1 1 1
4005 28321847 Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. 4 1 1
121 24399641 Psychological and educational interventions for atopic eczema in children. 2 1 1
6506 11869566 Maternal hydration for increasing amniotic fluid volume in oligohydramnios and normal amniotic fluid volume. 1 1 1
5120 23450563 Antibiotics for mastitis in breastfeeding women. 1 1 1
1955 16235273 Vaccines for preventing hepatitis B in health-care workers. 2 1 1
2218 27513702 Melatonin as add-on treatment for epilepsy. 3 1 1
4872 28602048 Injected corticosteroids for treating plantar heel pain in adults. 2 1 1
6543 19160174 Clozapine versus typical neuroleptic medication for schizophrenia. 1 1 1
181 26919512 Imaging modalities for the non-invasive diagnosis of endometriosis. 1 1 1
4989 11686978 Antibiotics for syphilis diagnosed during pregnancy. 2 1 1
1844 28639707 Dressings and topical agents for treating pressure ulcers. 1 1 1
5056 21735381 Interventions for treating oral lichen planus. 2 1 1
4944 27471845 Interventions for treating oral leukoplakia to prevent oral cancer. 2 1 1
2024 29063585 Early (< 8 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants. 9 1 1
1842 27748506 Bed rest for pressure ulcer healing in wheelchair users. 1 1 1
3285 14584002 Intravenous immunoglobulin for the treatment of Kawasaki disease in children. 2 1 1
510 25052054 (11)C-PIB-PET for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). 2 1 1
3636 30371937 Antibiotics for exacerbations of chronic obstructive pulmonary disease. 2 1 1
5216 27101467 Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis. 3 1 1
6327 27115477 Yoga for asthma. 1 1 1
3282 24788977 Anti-vascular endothelial growth factor for macular oedema secondary to central retinal vein occlusion. 3 1 1
6739 23235606 Palliative endobronchial brachytherapy for non-small cell lung cancer. 1 1 1
2306 30695817 Exercise-based cardiac rehabilitation for adults with heart failure. 1 1 1
4832 30371952 Heliox for croup in children. 2 1 1
2094 23152221 Antibiotics to prevent complications following tooth extractions. 3 1 1
2309 24771460 Exercise-based rehabilitation for heart failure. 1 1 1
3769 25856658 Mind and body therapy for fibromyalgia. 1 1 1
520 30168578 Antidepressants for treating depression in dementia. 1 1 1
129 26273799 Corticosteroids for treating optic neuritis. 4 1 1
2215 23633348 Ibuprofen with or without an antiemetic for acute migraine headaches in adults. 1 1 1
3650 23990350 Combined corticosteroid and long-acting beta(2)-agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease. 1 1 1
6662 25514250 Patient education for preventing diabetic foot ulceration. 1 1 1
336 25284270 Pulmonary rehabilitation for interstitial lung disease. 4 1 1
5133 25208209 Pre-hospital versus in-hospital thrombolysis for ST-elevation myocardial infarction. 2 1 1
6559 20464730 Exercise therapy for schizophrenia. 1 1 1
1941 24696098 Pneumococcal conjugate vaccines for preventing otitis media. 4 1 1
251 28349529 Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation of non-asphyxial out-of-hospital cardiac arrest. 2 1 1
3749 24129853 Anticonvulsants for fibromyalgia. 1 1 1
4900 19821358 Probiotics for the treatment of bacterial vaginosis. 1 1 1
5484 25929694 Transcranial direct current stimulation (tDCS) for improving aphasia in patients with aphasia after stroke. 2 1 1
127 22786490 Combined oral contraceptive pills for treatment of acne. 1 1 1
128 25597924 Complementary therapies for acne vulgaris. 2 1 1
2219 25162749 Methotrexate for induction of remission in ulcerative colitis. 8 1 1
301 26588711 Treatment for superficial infusion thrombophlebitis of the upper extremity. 2 1 1
2208 27091010 Drugs for the acute treatment of migraine in children and adolescents. 2 1 1
3847 23543581 Anti-D administration after spontaneous miscarriage for preventing Rhesus alloimmunisation. 2 1 1
4917 27327415 Betahistine for symptoms of vertigo. 1 1 1
4972 25344083 Probiotics for preventing ventilator-associated pneumonia. 2 1 1
306 21735402 Physical interventions to interrupt or reduce the spread of respiratory viruses. 3 1 1
6512 18646114 Interventions for skin changes caused by nerve damage in leprosy. 1 1 1
4973 25354013 Quantitative versus qualitative cultures of respiratory secretions for clinical outcomes in patients with ventilator-associated pneumonia. 2 1 1
1997 25978975 Sentinel lymph node biopsy followed by lymph node dissection for localised primary cutaneous melanoma. 2 1 1
4914 19821263 Pharmacotherapy for hypertension in the elderly. 2 1 1
256 26878327 Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation. 2 1 1
4974 26743945 Semi-recumbent position versus supine position for the prevention of ventilator-associated pneumonia in adults requiring mechanical ventilation. 2 1 1
3483 30325017 Anti-vascular endothelial growth factor for diabetic macular oedema: a network meta-analysis. 2 1 1
4913 18425901 Interventions for alopecia areata. 3 1 1
6320 27595415 Vitamin D for the management of asthma. 1 1 1
522 24569873 Aromatherapy for dementia. 1 1 1
6319 19160185 Vitamin C supplementation for asthma. 1 1 1
5222 23152224 Rectal 5-aminosalicylic acid for maintenance of remission in ulcerative colitis. 2 1 1
6742 23794187 Screening for lung cancer. 1 1 1
3639 23076942 Breathing exercises for chronic obstructive pulmonary disease. 1 1 1
5005 15495071 Prophylactic versus selective antibiotics for term newborn infants of mothers with risk factors for neonatal infection. 1 1 1
4006 25821121 Bed rest in singleton pregnancies for preventing preterm birth. 1 1 1
4007 23728668 Cervical pessary for preventing preterm birth. 3 1 1
2103 27472005 Fluoride mouthrinses for preventing dental caries in children and adolescents. 1 1 1
3773 28349517 Oral nonsteroidal anti-inflammatory drugs for fibromyalgia in adults. 1 1 1
6300 22513944 Regular treatment with formoterol for chronic asthma: serious adverse events. 1 1 1
1822 22972128 Interventions for mycosis fungoides. 5 1 1
3259 26967259 Interventions for preventing delirium in hospitalised non-ICU patients. 2 1 1
551 19370678 Enteral tube feeding for older people with advanced dementia. 1 1 1
10 21328305 Antidepressants for agitation and psychosis in dementia. 3 1 1
4821 25710134 Medical interventions for acanthamoeba keratitis. 2 1 1
553 25874613 Exercise programs for people with dementia. 1 1 1
6303 18646149 Regular treatment with salmeterol for chronic asthma: serious adverse events. 1 1 1
4010 23990333 Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth. 2 1 1
6761 17943757 Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis. 1 1 1
7 28197998 Laser-assisted subepithelial keratectomy (LASEK) versus laser-assisted in-situ keratomileusis (LASIK) for correcting myopia. 3 1 1
6762 30045416 Treatment for HIV-associated cryptococcal meningitis. 1 1 1
556 19160342 Galantamine for dementia in people with Down syndrome. 3 1 1
557 19160216 Ginkgo biloba for cognitive impairment and dementia. 2 1 1
4 22161388 Interventions to slow progression of myopia in children. 3 1 1
6294 24085631 Physical training for asthma. 1 1 1
6600 26289586 Transcranial magnetic stimulation (TMS) for schizophrenia. 1 1 1
2107 20091655 Fluoride toothpastes of different concentrations for preventing dental caries in children and adolescents. 1 1 1
5010 23881658 First-line allogeneic hematopoietic stem cell transplantation of HLA-matched sibling donors compared with first-line ciclosporin and/or antithymocyte or antilymphocyte globulin for acquired severe aplastic anemia. 3 1 1
4942 21249651 Glucocorticoids for croup. 1 1 1
502 25180668 Topical corticosteroids for treating phimosis in boys. 2 1 1
6347 17636779 Vaccines for preventing smallpox. 1 1 1
1833 25887212 TNF-alpha inhibitors for ankylosing spondylitis. 4 1 1
4943 24114291 Nebulized epinephrine for croup in children. 1 1 1
505 24108511 Antibiotics for the prophylaxis of bacterial endocarditis in dentistry. 2 1 1
4836 25080126 Inhaled anticholinergics and short-acting beta(2)-agonists versus short-acting beta2-agonists alone for children with acute asthma in hospital. 2 1 1
4840 27687114 Non-invasive positive pressure ventilation for acute asthma in children. 2 1 1
4990 21412896 Non-surgical interventions for convergence insufficiency. 1 1 1
3681 26490945 Long-acting beta2-agonist in addition to tiotropium versus either tiotropium or long-acting beta2-agonist alone for chronic obstructive pulmonary disease. 1 1 1
3629 25234126 Aclidinium bromide for stable chronic obstructive pulmonary disease. 1 1 1
6406 30403286 Ketogenic diets for drug-resistant epilepsy. 1 1 1
3765 28045473 Gabapentin for fibromyalgia pain in adults. 1 1 1
1856 25561248 Repositioning for treating pressure ulcers. 1 1 1
6731 17636828 Chemotherapy and surgery versus surgery alone in non-small cell lung cancer. 1 1 1
501 30560579 Thrombolytic therapy for pulmonary embolism. 4 1 1
2120 20238319 Pit and fissure sealants versus fluoride varnishes for preventing dental decay in children and adolescents. 1 1 1
4941 30133690 Glucocorticoids for croup in children. 1 1 1
1851 24919719 Nutritional interventions for preventing and treating pressure ulcers. 1 1 1
2174 24578248 Resection versus other treatments for locally advanced pancreatic cancer. 1 1 1
2297 22336795 Diuretics for heart failure. 1 1 1
2298 24938824 Early referral to specialist nephrology services for preventing the progression to end-stage kidney disease. 7 1 1
3294 26252501 Antibiotics for asymptomatic bacteriuria in pregnancy. 2 1 1
2037 23152263 Interventions for drooling in children with cerebral palsy. 1 1 1
3293 25066627 Antibiotics for acute pyelonephritis in children. 2 1 1
38 21678345 Early intervention for psychosis. 2 1 1
3631 27990628 Action plans with brief patient education for exacerbations in chronic obstructive pulmonary disease. 2 1 1
4615 21154382 Interventions for treating sexual dysfunction in patients with chronic kidney disease. 3 1 1
196 22258970 Pentoxifylline for endometriosis. 1 1 1
2550 25763979 Surgery for nonarteritic anterior ischemic optic neuropathy. 2 1 1
6217 23235591 Addition of intravenous aminophylline to inhaled beta(2)-agonists in adults with acute asthma. 1 1 1
659 28530031 Celecoxib for osteoarthritis. 3 1 1
660 28597983 Celecoxib for rheumatoid arthritis. 3 1 1
2348 28012165 Stem cell therapy for chronic ischaemic heart disease and congestive heart failure. 2 1 1
4048 16855970 Potassium containing toothpastes for dentine hypersensitivity. 2 1 1
6137 15674876 Acupuncture and dry-needling for low back pain. 1 1 1
6269 20687065 Injection allergen immunotherapy for asthma. 2 1 1
567 27869298 Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the early diagnosis of dementia across a variety of healthcare settings. 1 1 1
6285 15846609 Manual therapy for asthma. 1 1 1
3247 29920656 Antipsychotics for treatment of delirium in hospitalised non-ICU patients. 2 1 1
572 17054228 Massage and touch for dementia. 1 1 1
573 19160343 Memantine for dementia in people with Down syndrome. 3 1 1
6280 22592708 Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children. 1 1 1
6278 22972060 Ionisers for chronic asthma. 1 1 1
6277 27126744 Intravenous magnesium sulfate for treating children with acute asthma in the emergency department. 1 1 1
579 26760674 Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations. 4 1 1
6276 24865567 Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department. 1 1 1
583 30033623 Music-based therapeutic interventions for people with dementia. 2 1 1
4026 26142898 Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes. 2 1 1
4028 26490698 Risk-scoring systems for predicting preterm birth with the aim of reducing associated adverse outcomes. 1 1 1
1805 27171652 Psychosocial interventions for improving quality of life outcomes in adults undergoing strabismus surgery. 1 1 1
1804 23728647 Interventions for intermittent exotropia. 2 1 1
3215 25918921 Interventions for hirsutism (excluding laser and photoepilation therapy alone). 4 1 1
4806 25433518 Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents. 2 1 1
592 27911489 Palliative care interventions in advanced dementia. 1 1 1
595 27851868 Pharmacotherapies for sleep disturbances in dementia. 4 1 1
6216 24089325 Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma. 1 1 1
6218 23235685 Addition of intravenous beta(2)-agonists to inhaled beta(2)-agonists for acute asthma. 1 1 1
2339 28813123 Pharmacotherapy for hypertension in adults aged 18 to 59 years. 2 1 1
654 19821440 Biologics for rheumatoid arthritis: an overview of Cochrane reviews. 2 1 1
4060 25803325 Corneal collagen cross-linking for treating keratoconus. 1 1 1
3212 28589646 Focal laser treatment in addition to chemotherapy for retinoblastoma. 1 1 1
1785 25427003 Treatment for thoracic outlet syndrome. 13 1 1
624 28418065 Vitamin E for Alzheimer's dementia and mild cognitive impairment. 2 1 1
5264 23076907 Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus. 1 1 1
1782 21328260 Treatment for Lambert-Eaton myasthenic syndrome. 15 1 1
627 25629415 ¹⁸F-FDG PET for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). 3 1 1
628 29851031 Vaccines for preventing typhoid fever. 3 1 1
629 19821401 Abatacept for rheumatoid arthritis. 2 1 1
1781 25209127 Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). 16 1 1
2350 26517969 Structured telephone support or non-invasive telemonitoring for patients with heart failure. 1 1 1
5266 24132718 Surgical interventions for the early management of Bell's palsy. 2 1 1
6235 27649894 Cognitive behavioural therapy (CBT) for adults and adolescents with asthma. 1 1 1
634 16034967 Adalimumab for treating rheumatoid arthritis. 2 1 1
635 21328309 Adverse effects of biologics: a network meta-analysis and Cochrane overview. 5 1 1
641 11034691 Antimalarials for treating rheumatoid arthritis. 2 1 1
619 12917907 Validation therapy for dementia. 1 1 1
4063 27176573 Botulinum toxin type B for cervical dystonia. 3 1 1
1773 23744611 Selective serotonin reuptake inhibitors for premenstrual syndrome. 13 1 1
2356 19588353 Treatment blood pressure targets for hypertension. 2 1 1
1770 30596397 Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome. 17 1 1
2358 21975736 Adjuvant chemotherapy for endometrial cancer after hysterectomy. 3 1 1
649 17943920 Balneotherapy for osteoarthritis. 2 1 1
1768 28649802 Punctal occlusion for dry eye syndrome. 15 1 1
1766 22419287 Progesterone for premenstrual syndrome. 14 1 1
1799 28253424 Botulinum toxin for the treatment of strabismus. 4 1 1
3229 18254053 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women. 2 1 1
686 12076504 Electrical stimulation for the treatment of rheumatoid arthritis. 3 1 1
738 21975789 Pain management for rheumatoid arthritis and cardiovascular or renal comorbidity. 3 1 1
6156 24984082 Corticosteroids for dengue infection. 1 1 1
1723 29376560 Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome. 15 1 1
2389 30091808 Amphetamines for attention deficit hyperactivity disorder (ADHD) in adults. 1 1 1
4122 26171904 Interventions for preventing the progression of autosomal dominant polycystic kidney disease. 5 1 1
753 25603545 Rituximab for rheumatoid arthritis. 2 1 1
2394 15846741 Family therapy for attention-deficit disorder or attention-deficit/hyperactivity disorder in children and adolescents. 1 1 1
2974 16625534 Strategies for detecting colon cancer and/or dysplasia in patients with inflammatory bowel disease. 7 1 1
756 22071858 Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis). 6 1 1
6144 22336830 Hyperbaric oxygen therapy for Bell's palsy. 1 1 1
3121 12519620 Chemotherapy for high-grade glioma. 1 1 1
6140 21901707 Neurosurgical interventions for the treatment of classical trigeminal neuralgia. 1 1 1
3119 11687008 Biopsy versus resection for malignant glioma. 1 1 1
3149 17943780 Medical interventions for primary open angle glaucoma and ocular hypertension. 3 1 1
3150 28122126 Neuroprotection for treatment of glaucoma in adults. 2 1 1
3151 26618332 Optic nerve head and fibre layer imaging for diagnosing glaucoma. 1 1 1
715 23450553 Methotrexate for ankylosing spondylitis. 5 1 1
670 23076948 Curcumin for maintenance of remission in ulcerative colitis. 6 1 1
1756 22513943 Patellar taping for patellofemoral pain syndrome in adults. 13 1 1
4082 23888429 Opioids for acute pancreatitis pain. 2 1 1
675 10796412 Cyclosporine for rheumatoid arthritis. 2 1 1
676 19160281 Dietary interventions for rheumatoid arthritis. 2 1 1
1753 26905373 Over the counter (OTC) artificial tear drops for dry eye syndrome. 14 1 1
680 25264908 Down-titration and discontinuation strategies of tumor necrosis factor-blocking agents for rheumatoid arthritis in patients with low disease activity. 2 1 1
681 23152242 Doxycycline for osteoarthritis of the knee or hip. 2 1 1
682 19821388 Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis. 2 1 1
6160 26591003 Airway clearance techniques for bronchiectasis. 1 1 1
1758 27153153 Pharmacological treatment for Kleine-Levin syndrome. 15 1 1
1797 26915340 Topical treatments for scalp psoriasis. 2 1 1
737 22258995 Pain management for inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other spondylarthritis) and gastrointestinal or liver comorbidity. 6 1 1
3227 18253985 Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women. 2 1 1
6258 18425868 House dust mite control measures for asthma. 1 1 1
3226 25164988 Colchicine for pericarditis. 1 1 1
604 29493789 Reminiscence therapy for dementia. 1 1 1
1796 23543539 Topical treatments for chronic plaque psoriasis. 2 1 1
606 19160344 Rivastigmine for dementia in people with Down syndrome. 3 1 1
1789 26598969 Anti-TNF agents for paediatric psoriasis. 3 1 1
6214 28301050 Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma. 1 1 1
3187 25254615 Interventions for the management of oral ulcers in Behçet's disease. 4 1 1
1763 25756795 Positive pressure therapy for Ménière's disease or syndrome. 15 1 1
736 25229835 Oral or transdermal opioids for osteoarthritis of the knee or hip. 2 1 1
3148 16856103 Lens extraction for chronic angle-closure glaucoma. 1 1 1
4105 25503105 Mohs micrographic surgery versus surgical excision for periocular basal cell carcinoma. 3 1 1
6170 19160186 Inhaled steroids for bronchiectasis. 1 1 1
1734 21412917 Intratympanic gentamicin for Ménière's disease or syndrome. 13 1 1
4765 27885650 Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease. 2 1 1
3143 26352007 Intravitreal steroids versus observation for macular edema secondary to central retinal vein occlusion. 3 1 1
726 22258993 Muscle relaxants for pain management in rheumatoid arthritis. 2 1 1
727 22258992 Neuromodulators for pain management in rheumatoid arthritis. 2 1 1
728 23975674 Non-pharmacological interventions for fatigue in rheumatoid arthritis. 2 1 1
1731 23633371 Interventions for treating pain and disability in adults with complex regional pain syndrome. 13 1 1
731 25225849 Non-steroidal anti-inflammatory drugs for acute gout. 2 1 1
1730 27855478 Interventions for treating burning mouth syndrome. 15 1 1
733 14974005 Occupational therapy for rheumatoid arthritis. 2 1 1
735 26258748 Oral fumaric acid esters for psoriasis. 3 1 1
4131 21412875 Antibiotics for trachoma. 1 1 1
4126 27416004 Intracystic bleomycin for cystic craniopharyngiomas in children. 2 1 1
4133 25697765 Face washing promotion for preventing active trachoma. 1 1 1
1706 21563169 Folic acid for fragile X syndrome. 14 1 1
1701 25603546 Exercise for treating patellofemoral pain syndrome. 13 1 1
786 30199097 Antigen-specific active immunotherapy for ovarian cancer. 2 1 1
3102 18254038 Interventions for motor apraxia following stroke. 2 1 1
4738 27760454 Bisphosphonate therapy for osteogenesis imperfecta. 1 1 1
1694 21412893 Dopamine agonists for restless legs syndrome. 13 1 1
2417 30091458 Sodium valproate versus phenytoin monotherapy for epilepsy: an individual participant data review. 3 1 1
4177 26509249 Growth factors for treating diabetic foot ulcers. 3 1 1
1689 20824872 Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy. 15 1 1
1688 25785660 Corticosteroid therapy for nephrotic syndrome in children. 15 1 1
4732 22972070 Empiric antibiotic coverage of atypical pathogens for community-acquired pneumonia in hospitalized adults. 2 1 1
6100 26022367 Directly observed therapy for treating tuberculosis. 1 1 1
6099 27121755 Corticosteroids for managing tuberculous meningitis. 2 1 1
807 27737492 Laparoscopy versus laparotomy for FIGO stage I ovarian cancer. 2 1 1
4165 25188210 Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus. 2 1 1
4168 29205264 Diet, physical activity or both for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased risk of developing type 2 diabetes mellitus. 2 1 1
6061 27010219 Physical fitness training for stroke patients. 1 1 1
1681 21833945 Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome. 13 1 1
4172 16855995 Exercise for type 2 diabetes mellitus. 2 1 1
4173 18646086 Exercise or exercise and diet for preventing type 2 diabetes mellitus. 3 1 1
6086 25072528 Thrombolysis for acute ischaemic stroke. 1 1 1
5345 17636770 Oral water soluble contrast for the management of adhesive small bowel obstruction. 1 1 1
4169 18646120 Dietary advice for the prevention of type 2 diabetes mellitus in adults. 2 1 1
1657 26771164 Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis. 9 1 1
3001 15674897 Interventions for the treatment of burning mouth syndrome. 1 1 1
902 22895952 Psychological therapies for people with borderline personality disorder. 2 1 1
1702 28444695 Exercise therapy for chronic fatigue syndrome. 15 1 1
6126 25403701 Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment. 1 1 1
6025 25353321 Interventions for deliberately altering blood pressure in acute stroke. 1 1 1
6127 17943842 Rifabutin for treating pulmonary tuberculosis. 1 1 1
2429 29192424 Interventions for Old World cutaneous leishmaniasis. 3 1 1
842 26333656 Beta2-agonists for acute cough or a clinical diagnosis of acute bronchitis. 3 1 1
5826 23728638 Mitoxantrone for multiple sclerosis. 2 1 1
848 28626902 Haemophilus influenzae oral vaccination for preventing acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease. 4 1 1
1674 28319266 Benzodiazepines for restless legs syndrome. 14 1 1
4195 22258959 Self-monitoring of blood glucose in patients with type 2 diabetes mellitus who are not using insulin. 2 1 1
3060 25927098 Surgery for small asymptomatic abdominal aortic aneurysms. 3 1 1
1672 29797697 Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome. 15 1 1
2431 24947503 Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease. 3 1 1
6074 27545611 Self management programmes for quality of life in people with stroke. 1 1 1
5356 19370684 Thalidomide and thalidomide analogues for induction of remission in Crohn's disease. 2 1 1
4194 17636824 Rosiglitazone for type 2 diabetes mellitus. 2 1 1
2435 16856010 Ergonomic and physiotherapeutic interventions for treating work-related complaints of the arm, neck or shoulder in adults. 1 1 1
1665 22592702 Acupuncture for treatment of irritable bowel syndrome. 13 1 1
2437 17443508 Local corticosteroid injection for carpal tunnel syndrome. 1 1 1
839 30062732 Antibiotics for prolonged wet cough in children. 2 1 1
838 28626858 Antibiotics for acute bronchitis. 1 1 1
4999 24915629 Intrapartum antibiotics for known maternal Group B streptococcal colonization. 1 1 1
4179 21735405 Insulin detemir versus insulin glargine for type 2 diabetes mellitus. 2 1 1
4155 28787537 Blood pressure targets for hypertension in older adults. 3 1 1
4134 26568232 Interventions for trachoma trichiasis. 2 1 1
2399 29744873 Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of adverse events in non-randomised studies. 2 1 1
2400 26599576 Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD). 1 1 1
775 29271481 Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis. 4 1 1
776 15266544 Tai chi for treating rheumatoid arthritis. 3 1 1
4226 16625645 Exercise or other physical activity for preventing pre-eclampsia and its complications. 2 1 1
2460 17943890 Interventions for the prevention of nutritional rickets in term born children. 1 1 1
1632 28738443 Urethral injection therapy for urinary incontinence in women. 1 1 1
3011 28700811 Probing for congenital nasolacrimal duct obstruction. 5 1 1
5363 17054230 Exercise for women receiving adjuvant therapy for breast cancer. 1 1 1
6052 24026639 Organised inpatient (stroke unit) care for stroke. 1 1 1
860 28181687 Acupuncture for acute hordeolum. 3 1 1
862 28068454 Non-surgical interventions for acute internal hordeolum. 2 1 1
865 20614457 Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD). 2 1 1
4132 22336798 Environmental sanitary interventions for preventing active trachoma. 1 1 1
3036 23076900 Cerebrospinal fluid drainage for thoracic and thoracoabdominal aortic aneurysm surgery. 3 1 1
4707 20464739 Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children. 2 1 1
4706 26594816 Addition of long-acting beta2-agonists to inhaled corticosteroids for chronic asthma in children. 2 1 1
873 19588408 Multiple session early psychological interventions for the prevention of post-traumatic stress disorder. 1 1 1
4704 19821344 Addition of inhaled long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children. 2 1 1
876 25001071 Pharmacological interventions for preventing post-traumatic stress disorder (PTSD). 2 1 1
4216 17443552 Antiplatelet agents for preventing pre-eclampsia and its complications. 2 1 1
879 12076399 Psychological debriefing for preventing post traumatic stress disorder (PTSD). 1 1 1
1642 25992494 Intravenous immunoglobulin for presumed viral myocarditis in children and adults. 5 1 1
6036 18843644 Interventions for treating depression after stroke. 1 1 1
3026 21901699 Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. 2 1 1
884 23235632 Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents. 1 1 1
3024 17253532 Prevention and treatment of cryptosporidiosis in immunocompromised patients. 2 1 1
6032 18646094 Interventions for preventing depression after stroke. 1 1 1
889 20091620 Sports and games for post-traumatic stress disorder (PTSD). 1 1 1
6027 25767912 Interventions for improving community ambulation in individuals with stroke. 1 1 1
3019 25352226 Strategies of testing for syphilis during pregnancy. 3 1 1
894 20687091 Pharmacological interventions for antisocial personality disorder. 4 1 1
895 20556762 Pharmacological interventions for borderline personality disorder. 2 1 1
2442 27845501 Treatment for ulnar neuropathy at the elbow. 3 1 1
1636 23836411 Weighted vaginal cones for urinary incontinence. 1 1 1
6023 24453023 Insulin for glycaemic control in acute ischaemic stroke. 1 1 1
1621 25261861 Surgery for stress urinary incontinence due to presumed sphincter deficiency after prostate surgery. 4 1 1
3010 27003123 Teriflunomide for multiple sclerosis. 4 1 1
4230 23728666 Interventions for clinical and subclinical hypothyroidism pre-pregnancy and during pregnancy. 5 1 1
4232 21154341 Magnesium sulphate versus diazepam for eclampsia. 2 1 1
4233 20824833 Magnesium sulphate versus lytic cocktail for eclampsia. 2 1 1
3005 22336789 Non surgical therapy for anal fissure. 2 1 1
4234 20927719 Magnesium sulphate versus phenytoin for eclampsia. 2 1 1
5384 28707751 Oral antifungal medication for toenail onychomycosis. 1 1 1
5385 17636672 Topical treatments for fungal infections of the skin and nails of the foot. 1 1 1
918 25523166 Intermittent self-dilatation for urethral stricture disease in males. 3 1 1
3045 28548204 Endovascular treatment for ruptured abdominal aortic aneurysm. 4 1 1
2997 29708265 Interventions for preventing occupational irritant hand dermatitis. 1 1 1
2992 22336810 Dietary supplements for established atopic eczema. 1 1 1
2459 25511415 Stereotactic radiotherapy for vestibular schwannoma. 2 1 1
2990 25348587 Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes. 6 1 1
932 20927758 Antibiotic prophylaxis for patients undergoing elective endoscopic retrograde cholangiopancreatography. 4 1 1
5992 28430363 Cerebrolysin for acute ischaemic stroke. 1 1 1
1618 23881652 Simple behavioural interventions for nocturnal enuresis in children. 3 1 1
936 23813477 Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis. 4 1 1
5988 25317988 Beta-blockers for preventing stroke recurrence. 1 1 1
4249 16625644 Rest during pregnancy for preventing pre-eclampsia and its complications in women with normal blood pressure. 2 1 1
5396 16034917 Herbal medicines for treating HIV infection and AIDS. 2 1 1
2479 26756331 Anticoagulant treatment for subsegmental pulmonary embolism. 2 1 1
4679 23235609 Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients. 1 1 1
6020 25387992 Hyperbaric oxygen therapy for acute ischaemic stroke. 1 1 1
3172 21563135 Interventions targeted at women to encourage the uptake of cervical screening. 1 1 1
4207 16235411 Altered dietary salt for preventing pre-eclampsia, and its complications. 2 1 1
687 23450527 Erythropoiesis-stimulating agents for anemia in rheumatoid arthritis. 3 1 1
1307 21249695 Cisapride for intestinal constipation. 3 1 1
4497 30068022 Natalizumab for induction of remission in Crohn's disease. 3 1 1
2702 30379327 Laparoscopy versus laparotomy for the management of early stage endometrial cancer. 3 1 1
5578 23440782 Vitamin C for preventing and treating the common cold. 1 1 1
5579 23775705 Zinc for the common cold. 1 1 1
4500 25087045 Aspirin as adjunctive treatment for giant cell arteritis. 1 1 1
2631 25407135 Tonsillectomy or adenotonsillectomy versus non-surgical treatment for chronic/recurrent acute tonsillitis. 2 1 1
2695 22895938 Chemotherapy for advanced, recurrent or metastatic endometrial carcinoma. 4 1 1
1488 26068959 Reduction in saturated fat intake for cardiovascular disease. 1 1 1
2564 24782304 Oral contraceptives for functional ovarian cysts. 2 1 1
2483 21833941 Anticoagulation for cerebral venous sinus thrombosis. 4 1 1
5448 20824834 Non-steroid agents for idiopathic pulmonary fibrosis. 2 1 1
1005 28771289 Screening for gestational diabetes mellitus based on different risk profiles and settings for improving maternal and infant health. 4 1 1
1008 19588341 Treatments for gestational diabetes. 3 1 1
1577 28631307 Interventions for the prevention of recurrent erysipelas and cellulitis. 2 1 1
2941 27884041 Follow-up strategies for patients treated for non-metastatic colorectal cancer. 2 1 1
1576 20556757 Interventions for cellulitis and erysipelas. 3 1 1
1012 28225198 Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure. 4 1 1
1014 24089293 Anti-vascular endothelial growth factor for neovascular glaucoma. 2 1 1
4294 24357340 Vitamin A and fish oils for retinitis pigmentosa. 2 1 1
1018 22696344 Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract. 1 1 1
5920 17636709 Occupational therapy for patients with Parkinson's disease. 1 1 1
5915 26447539 Interventions for fatigue in Parkinson's disease. 1 1 1
4300 25851268 Antibiotics for asymptomatic bacteriuria. 1 1 1
5441 23076914 Interventions for primary (intrinsic) tracheomalacia in children. 1 1 1
2520 28892556 Parenteral anticoagulation in ambulatory patients with cancer. 4 1 1
5661 25300703 Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment. 1 1 1
5576 25892369 Saline nasal irrigation for acute upper respiratory tract infections. 1 1 1
2502 24804622 Heparin for the prevention of venous thromboembolism in acutely ill medical patients (excluding stroke and myocardial infarction). 4 1 1
4493 20927729 Sedatives for opiate withdrawal in newborn infants. 1 1 1
2656 24500927 Antiviral treatment for preventing postherpetic neuralgia. 1 1 1
5609 18843658 Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people. 2 1 1
2659 23543541 Corticosteroids for preventing postherpetic neuralgia. 1 1 1
1327 26387487 Interventions for preventing postpartum constipation. 1 1 1
2638 23450562 Surgery for Ménière's disease. 1 1 1
2636 11279734 Betahistine for Menière's disease or syndrome. 1 1 1
5651 22696354 Artesunate versus quinine for treating severe malaria. 1 1 1
5566 23818046 Acetaminophen (paracetamol) for the common cold in adults. 1 1 1
2719 25300167 Antibiotics for bronchiolitis in children under two years of age. 3 1 1
5567 26615034 Antihistamines for the common cold. 1 1 1
1287 24604671 Vaccines for preventing influenza in people with cystic fibrosis. 2 1 1
5680 22336792 Intermittent preventive treatment for malaria in children living in areas with seasonal transmission. 1 1 1
5679 25582096 Intermittent preventive antimalarial treatment for children with anaemia. 1 1 1
1290 24823922 Vitamin D supplementation for cystic fibrosis. 1 1 1
4485 27149418 Corticosteroids for the treatment of Duchenne muscular dystrophy. 2 1 1
5675 15106149 Insecticide-treated bed nets and curtains for preventing malaria. 2 1 1
5570 24554461 Echinacea for preventing and treating the common cold. 1 1 1
5673 20393950 Indoor residual spraying for preventing malaria. 1 1 1
5571 25386977 Garlic for the common cold. 1 1 1
5572 28849871 Heated, humidified air for the common cold. 1 1 1
5573 27748955 Nasal decongestants in monotherapy for the common cold. 1 1 1
5574 26387658 Non-steroidal anti-inflammatory drugs for the common cold. 1 1 1
2709 23440805 Primary surgery versus primary radiotherapy with or without chemotherapy for early adenocarcinoma of the uterine cervix. 4 1 1
4492 20927730 Opiate treatment for opiate withdrawal in newborn infants. 1 1 1
5666 17443590 Electronic mosquito repellents for preventing mosquito bites and malaria infection. 1 1 1
2919 18425924 Huperzine A for Alzheimer's disease. 2 1 1
4312 24820100 Intermittent pneumatic compression for treating venous leg ulcers. 1 1 1
2662 26937872 Vaccines for preventing herpes zoster in older adults. 2 1 1
5948 19821336 Pneumococcal conjugate vaccines for preventing vaccine-type invasive pneumococcal disease and X-ray defined pneumonia in children less than two years of age. 1 1 1
5945 24615334 Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults. 1 1 1
2948 29388687 Interventions for weight reduction in obesity to improve survival in women with endometrial cancer. 4 1 1
984 28832911 Different strategies for diagnosing gestational diabetes to improve maternal and infant health. 1 1 1
985 28236296 Different types of dietary advice for women with gestational diabetes mellitus. 5 1 1
5944 30264525 Oral care measures for preventing nursing home-acquired pneumonia. 1 1 1
5943 16625618 Oral antibiotics versus parenteral antibiotics for severe pneumonia in children. 1 1 1
2498 28182249 Fixed dose subcutaneous low molecular weight heparins versus adjusted dose unfractionated heparin for the initial treatment of venous thromboembolism. 1 1 1
989 28639706 Exercise for pregnant women with gestational diabetes for improving maternal and fetal outcomes. 3 1 1
5941 23076954 Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with community-acquired pneumonia. 2 1 1
5940 30601584 Chest physiotherapy for pneumonia in children. 1 1 1
992 28836274 Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes. 1 1 1
5939 23450568 Chest physiotherapy for pneumonia in adults. 1 1 1
994 28472859 Lifestyle interventions for the treatment of women with gestational diabetes. 4 1 1
5938 23733365 Antibiotics for community-acquired pneumonia in children. 1 1 1
2500 30390397 Graduated compression stockings for prevention of deep vein thrombosis. 3 1 1
998 28120427 Oral anti-diabetic pharmacological therapies for the treatment of women with gestational diabetes. 2 1 1
2902 26493047 Prenatal education for congenital toxoplasmosis. 1 1 1
4325 28240353 Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review. 2 1 1
1062 24532038 Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy. 4 1 1
1501 24825181 Yoga for the primary prevention of cardiovascular disease. 1 1 1
5831 12917976 Occupational therapy for multiple sclerosis. 1 1 1
693 23728635 Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis. 3 1 1
5827 17443610 Multidisciplinary rehabilitation for adults with multiple sclerosis. 1 1 1
4372 26992929 Antipsychotic medications for cocaine dependence. 1 1 1
1512 12535426 Tamsulosin for benign prostatic hyperplasia. 3 1 1
5946 22419316 Oxygen therapy for pneumonia in adults. 2 1 1
5949 18425930 Short-course versus long-course antibiotic therapy for non-severe community-acquired pneumonia in children aged 2 months to 59 months. 1 1 1
4313 26932818 Interventions for helping people adhere to compression treatments for venous leg ulceration. 1 1 1
5952 23925826 Vitamin C for preventing and treating pneumonia. 1 1 1
4315 23440784 Skin grafting for venous leg ulcers. 1 1 1
1045 24504975 Occlusion for stimulus deprivation amblyopia. 2 1 1
1553 22513921 Treatment for cramps in amyotrophic lateral sclerosis/motor neuron disease. 3 1 1
1048 28192644 Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery. 2 1 1
1049 26871761 Peripheral iridotomy for pigmentary glaucoma. 5 1 1
1051 25950286 Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments. 4 1 1
1550 22419278 Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND). 3 1 1
5000 25815707 Intravenous immunoglobulin for suspected or proven infection in neonates. 1 1 1
1056 28206671 Surgery for cataracts in people with age-related macular degeneration. 4 1 1
2905 22336839 Antibiotics for leptospirosis. 1 1 1
2904 19588424 Antibiotic prophylaxis for leptospirosis. 1 1 1
1549 23728676 Repetitive transcranial magnetic stimulation for the treatment of amyotrophic lateral sclerosis or motor neuron disease. 3 1 1
1003 24515533 Screening and subsequent management for gestational diabetes for improving maternal and infant health. 1 1 1
5933 17443568 Interventions for pityriasis rosea. 1 1 1
2823 20824827 Short-course antibiotics for acute otitis media. 1 1 1
982 27055233 Different intensities of glycaemic control for women with gestational diabetes mellitus. 4 1 1
1602 25517397 Mechanical devices for urinary incontinence in women. 1 1 1
4673 25526426 Antibiotic regimens for management of intra-amniotic infection. 4 1 1
2488 18843686 Combined intermittent pneumatic leg compression and pharmacological prophylaxis for prevention of venous thromboembolism in high-risk patients. 2 1 1
5415 24832785 Adjuvant chemotherapy for advanced endometrial cancer. 2 1 1
5417 22513918 Adjuvant radiotherapy for stage I endometrial cancer. 2 1 1
1592 27935011 Electrical stimulation with non-implanted electrodes for overactive bladder in adults. 2 1 1
5955 27915460 Zinc supplementation for the prevention of pneumonia in children aged 2 months to 59 months. 1 1 1
2325 28902412 Interventions for treating tuberculous pericarditis. 5 1 1
5953 30024634 Vitamin D as an adjunct to antibiotics for the treatment of acute childhood pneumonia. 1 1 1
1371 26599079 Surgery for complete (full-thickness) rectal prolapse in adults. 2 1 1
4665 16437461 Anticoagulants versus non-steroidal anti-inflammatories or placebo for treatment of venous thromboembolism. 1 1 1
2663 25300166 Antibiotics for community-acquired pneumonia in adult outpatients. 2 1 1
1232 21412868 Inhaled antibiotics for long-term therapy in cystic fibrosis. 1 1 1
2757 26400765 Interventions for renal vasculitis in adults. 7 1 1
2600 17054173 Malaria chemoprophylaxis in sickle cell disease. 3 1 1
1440 26558642 Steroids for symptom control in infectious mononucleosis. 3 1 1
4575 22513963 Anaesthesia for evacuation of incomplete miscarriage. 2 1 1
1438 27933614 Antiviral agents for infectious mononucleosis (glandular fever). 2 1 1
5715 17054281 Vaccines for preventing malaria (blood-stage). 1 1 1
2587 30480767 Gene therapy for sickle cell disease. 2 1 1
5712 25921416 Tafenoquine for preventing relapse in people with Plasmodium vivax malaria. 1 1 1
4458 19588379 The effects of antimicrobial therapy on bacterial vaginosis in non-pregnant women. 2 1 1
2609 25966336 Psychological therapies for sickle cell disease and pain. 1 1 1
5707 21735422 Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries. 1 1 1
5706 25519857 Rapid diagnostic tests for diagnosing uncomplicated non-falciparum or Plasmodium vivax malaria in endemic countries. 1 1 1
2740 29265171 Nebulised hypertonic saline solution for acute bronchiolitis in infants. 2 1 1
1259 27878805 Pancreatic enzyme replacement therapy for people with cystic fibrosis. 1 1 1
1261 29090734 Physical exercise training for cystic fibrosis. 1 1 1
1263 26083308 Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis. 1 1 1
2615 27502327 Treatment for avascular necrosis of bone in people with sickle cell disease. 4 1 1
1266 26270620 Prolonged antibiotics for non-cystic fibrosis bronchiectasis in children and adults. 2 1 1
5693 23986463 Mosquito larval source management for controlling malaria. 1 1 1
5558 24944120 Antimicrobial drugs for treating cholera. 1 1 1
5560 21412922 Oral vaccines for preventing cholera. 1 1 1
1214 25102015 Antioxidant supplementation for lung disease in cystic fibrosis. 1 1 1
2775 23903965 Prenatal administration of progesterone for preventing preterm birth in women considered to be at risk of preterm birth. 2 1 1
1489 28290160 Risk scoring for the primary prevention of cardiovascular disease. 2 1 1
2801 23728660 Autoinflation for hearing loss associated with otitis media with effusion. 1 1 1
1234 27552284 Inhaled corticosteroids for cystic fibrosis. 1 1 1
1447 25133974 Spectacle correction versus no spectacles for prevention of strabismus in hyperopic children. 5 1 1
4404 30117155 Assisted reproductive technology: an overview of Cochrane Reviews. 2 1 1
1448 25315969 Strabismus surgery before versus after completion of amblyopia therapy in children. 2 1 1
696 20091667 Golimumab for rheumatoid arthritis. 3 1 1
5294 17943888 Psychosocial and psychological interventions for treating postpartum depression. 1 1 1
5293 23450532 Psychosocial and psychological interventions for preventing postpartum depression. 1 1 1
1744 27467116 Local anaesthetic sympathetic blockade for complex regional pain syndrome. 14 1 1
2664 17054253 Strontium ranelate for preventing and treating postmenopausal osteoporosis. 3 1 1
6187 11034745 Surgery vs non-surgical treatment for bronchiectasis. 1 1 1
6186 25997166 Stopping long-acting beta2-agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids. 2 1 1
1741 21328278 Levodopa for restless legs syndrome. 13 1 1
4099 28231605 Endonasal versus external dacryocystorhinostomy for nasolacrimal duct obstruction. 1 1 1
3158 27873308 Adjuvant platinum-based chemotherapy for early stage cervical cancer. 2 1 1
704 26258874 Interventions for preventing and treating kidney disease in Henoch-Schönlein Purpura (HSP). 8 1 1
3157 28218404 Topical medication instillation techniques for glaucoma. 3 1 1
1738 26645724 Knee orthoses for treating patellofemoral pain syndrome. 14 1 1
4102 17253489 Interventions for basal cell carcinoma of the skin. 3 1 1
710 12535423 Leflunomide for treating rheumatoid arthritis. 3 1 1
1737 30609006 Iron for the treatment of restless legs syndrome. 14 1 1
5976 23633327 The medical use of cannabis for reducing morbidity and mortality in patients with HIV/AIDS. 1 1 1
5954 21975768 Zinc supplementation as an adjunct to antibiotics in the treatment of pneumonia in children 2 to 59 months of age. 1 1 1
4259 28436019 Antibiotic therapy for pelvic inflammatory disease. 2 1 1
5717 16625647 Vaccines for preventing malaria (SPf66). 1 1 1
2772 25397904 H1-antihistamines for chronic spontaneous urticaria. 1 1 1
1218 24627308 Bisphosphonates for osteoporosis in people with cystic fibrosis. 2 1 1
1220 26688006 Chest physiotherapy compared to no chest physiotherapy for cystic fibrosis. 1 1 1
2769 24558013 Medical treatment for botulism. 2 1 1
4442 26695736 Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy. 2 1 1
1486 22592684 Reduced or modified dietary fat for preventing cardiovascular disease. 1 1 1
714 24065456 Magnetic resonance imaging, magnetic resonance arthrography and ultrasonography for assessing rotator cuff tears in people with shoulder pain for whom surgery is being considered. 4 1 1
1163 12804462 Regular self-examination or clinical examination for early detection of breast cancer. 1 1 1
2623 27900772 Hematopoietic stem cell transplantation for people with ß-thalassaemia major. 2 1 1
1280 27314455 Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease. 3 1 1
1350 28737843 Non-steroidal anti-inflammatory drugs (NSAIDs) for cancer-related pain in children and adolescents. 4 1 1
4511 26488459 Stiripentol for focal refractory epilepsy. 3 1 1
1330 25246307 Interventions for treating postpartum constipation. 1 1 1
5639 22972057 Antipyretic measures for treating fever in malaria. 1 1 1
1334 20614462 Lactulose versus Polyethylene Glycol for Chronic Constipation. 1 1 1
4515 15266488 Pharmacotherapy for patellofemoral pain syndrome. 1 1 1
4517 22972130 Allergen-specific oral immunotherapy for peanut allergy. 3 1 1
5635 27991651 Oxygen therapy for acute myocardial infarction. 1 1 1
4539 24934383 Powered versus manual toothbrushing for oral health. 2 1 1
5632 26310586 Combined oral contraceptives: the risk of myocardial infarction and ischemic stroke. 2 1 1
1381 25809586 Xylitol-containing products for preventing dental caries in children and adults. 2 1 1
4537 21154357 Different powered toothbrushes for plaque control and gingival health. 2 1 1
2675 24293353 Intranasal steroids for acute sinusitis. 1 1 1
1346 26482422 Milnacipran for pain in fibromyalgia in adults. 2 1 1
2651 25228233 Acellular vaccines for preventing whooping cough in children. 1 1 1
5564 20687062 Vaccines for preventing cholera: killed whole cell or other subunit vaccines (injected). 1 1 1
2652 17636756 Antibiotics for whooping cough (pertussis). 1 1 1
2670 26461493 Corticosteroids for the common cold. 3 1 1
5621 21154344 Prophylactic methylxanthine for prevention of apnoea in preterm infants. 1 1 1
4533 23235683 Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis patients. 2 1 1
1164 29620792 Risk-reducing mastectomy for the prevention of primary breast cancer. 2 1 1
2667 30198548 Antibiotics for acute rhinosinusitis in adults. 1 1 1
2653 25243777 Symptomatic treatment of the cough in whooping cough. 1 1 1
2669 24190439 Antibiotics for sore throat. 4 1 1
2625 23986406 Herbal medicines for viral myocarditis. 1 1 1
5626 23543583 Nidotherapy for people with schizophrenia. 2 1 1
1481 29112241 Periodontal therapy for the management of cardiovascular disease in patients with chronic periodontitis. 3 1 1
2798 27290722 Antibiotics for otitis media with effusion in children. 1 1 1
2815 24338106 Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media. 1 1 1
1168 29376219 Selenium for preventing cancer. 11 1 1
2778 20824832 Antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding. 2 1 1
2816 21563132 Oral or topical nasal steroids for hearing loss associated with otitis media with effusion in children. 1 1 1
1485 25519688 Reduced dietary salt for the prevention of cardiovascular disease. 1 1 1
5501 29388196 Vaccines for preventing influenza in healthy adults. 1 1 1
2807 29039160 Influenza vaccines for preventing acute otitis media in infants and children. 3 1 1
2805 29741289 Grommets (ventilation tubes) for recurrent acute otitis media in children. 1 1 1
2802 18646076 Decongestants and antihistamines for acute otitis media in children. 1 1 1
2800 21901683 Antihistamines and/or decongestants for otitis media with effusion (OME) in children. 1 1 1
2586 29546732 Folate supplementation in people with sickle cell disease. 4 1 1
2799 17054203 Antibiotics for the prevention of acute and chronic suppurative otitis media in children. 1 1 1
1166 23737396 Screening for breast cancer with mammography. 1 1 1
2781 19160207 Antibiotics for spontaneous bacterial peritonitis in cirrhotic patients. 2 1 1
4595 25300168 Androgens for the anaemia of chronic kidney disease in adults. 2 1 1
2797 26099233 Antibiotics for acute otitis media in children. 2 1 1
1207 23737089 Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis. 2 1 1
5754 25105982 Surgery for weight loss in adults. 1 1 1
1200 21154394 Second-generation antipsychotics for obsessive compulsive disorder. 1 1 1
1469 25940444 Influenza vaccines for preventing cardiovascular disease. 2 1 1
1208 28440853 Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis. 1 1 1
1474 26272648 Multiple risk factor interventions for primary prevention of cardiovascular disease in low- and middle-income countries. 1 1 1
2795 20091650 Adenoidectomy for otitis media in children. 4 1 1
5520 25730344 Adjuvant chemotherapy for resected early-stage non-small cell lung cancer. 2 1 1
781 22972108 Topical NSAIDs for chronic musculoskeletal pain in adults. 1 0 1
782 12918009 Transcutaneous electrical nerve stimulation (TENS) for the treatment of rheumatoid arthritis in the hand. 2 0 1
783 26468973 Acupuncture for cancer pain in adults. 4 0 1
784 26676202 Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer. 2 0 1
785 21901715 Angiogenesis inhibitors for the treatment of ovarian cancer. 1 0 1
787 22419327 Centralisation of services for gynaecological cancer. 1 0 1
788 10796788 Chemotherapy for advanced ovarian cancer. Advanced Ovarian Cancer Trialists Group. 2 0 1
789 21412906 Chemotherapy for malignant germ cell ovarian cancer in adult patients with early stage, advanced and recurrent disease. 1 0 1
155 21412923 Pharmacological treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for Guillain Barré syndrome. 14 0 1
790 22895947 Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer. 1 0 1
791 10796477 Clomiphene citrate for ovulation induction in women with oligo-amenorrhoea. 1 0 1
818 30298516 Positron emission tomography (PET) and magnetic resonance imaging (MRI) for assessing tumour resectability in advanced epithelial ovarian/fallopian tube/primary peritoneal cancer. 2 0 1
453 20614427 Interventions for treating oral candidiasis for patients with cancer receiving treatment. 2 0 1
452 21069679 Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children. 2 0 1
451 21833970 Interventions for prevention and treatment of vulvovaginal candidiasis in women with HIV infection. 2 0 1
151 25519471 Interventions for fatigue in peripheral neuropathy. 4 0 1
780 23728701 Topical herbal therapies for treating osteoarthritis. 3 0 1
154 25855461 Pharmacological treatment for pain in Guillain-Barré syndrome. 14 0 1
811 20091648 Management of drainage for malignant ascites in gynaecological cancer. 2 0 1
768 19821426 Single dose oral tiaprofenic acid for acute postoperative pain in adults. 5 0 1
779 20614469 Tocilizumab for rheumatoid arthritis. 2 0 1
793 20556785 Cytoreductive surgery plus chemotherapy versus chemotherapy alone for recurrent epithelial ovarian cancer. 1 0 1
812 21833960 Optimal primary surgical treatment for advanced epithelial ovarian cancer. 1 0 1
157 28241090 Plasma exchange for Guillain-Barré syndrome. 14 0 1
813 20614464 Palliative surgery versus medical management for bowel obstruction in ovarian cancer. 1 0 1
814 24142521 Pegylated liposomal doxorubicin for first-line treatment of epithelial ovarian cancer. 4 0 1
815 23835762 Pegylated liposomal doxorubicin for relapsed epithelial ovarian cancer. 4 0 1
816 24027084 Perioperative nutrition interventions for women with ovarian cancer. 1 0 1
806 30907434 Laparoscopy for diagnosing resectability of disease in women with advanced ovarian cancer. 3 0 1
794 20556786 DNA-repair pathway inhibitors for the treatment of ovarian cancer. 1 0 1
792 20091498 Clomiphene citrate for unexplained subfertility in women. 1 0 1
778 12076454 Thermotherapy for treating rheumatoid arthritis. 2 0 1
769 12535502 Splints/orthoses in the treatment of rheumatoid arthritis. 2 0 1
770 15846731 Sulfasalazine for ankylosing spondylitis. 5 0 1
771 10796400 Sulfasalazine for rheumatoid arthritis. 2 0 1
772 20091587 Surgical interventions for the rheumatoid shoulder. 2 0 1
773 23440830 Surgical versus conservative interventions for displaced intra-articular calcaneal fractures. 1 0 1
774 22895975 Surgical versus conservative interventions for treating ankle fractures in adults. 2 0 1
777 12137714 Therapeutic ultrasound for the treatment of rheumatoid arthritis. 2 0 1
810 23813336 Maintenance chemotherapy for ovarian cancer. 1 0 1
156 27846348 Pharmacological treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for Guillain-Barré syndrome. 15 0 1
123 22972132 Topical cyclosporine for atopic keratoconjunctivitis. 3 0 1
208 30650189 Postoperative epidural analgesia versus systemic analgesia for thoraco-lumbar spine surgery in children. 3 0 1
120 30480774 Probiotics for treating eczema. 2 0 1
130 17943841 Dehydroepiandrosterone for systemic lupus erythematosus. 3 0 1
131 25879093 Dehydroepiandrosterone for women in the peri- or postmenopausal phase. 2 0 1
132 28476075 Drugs for discoid lupus erythematosus. 3 0 1
148 10908498 Corticosteroids for treating Guillain-Barré syndrome. 1 0 1
133 29607496 Enteral nutritional therapy for induction of remission in Crohn's disease. 6 0 1
136 11279732 Laser resurfacing for facial acne scars. 1 0 1
137 21735412 Lifestyle changes in women with polycystic ovary syndrome. 3 0 1
140 30484286 Oral isotretinoin for acne. 5 0 1
141 29125183 Ovarian surgery for symptom relief in women with polycystic ovary syndrome. 19 0 1
142 22419284 Progestagens and anti-progestagens for pain associated with endometriosis. 3 0 1
143 28742263 Progesterone receptor modulators for endometriosis. 3 0 1
144 23633314 Skin patch and vaginal ring versus combined oral contraceptives for contraception. 5 0 1
145 19370553 Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne. 2 0 1
146 21975784 Statins for women with polycystic ovary syndrome not actively trying to conceive. 15 0 1
134 17253562 Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome. 5 0 1
175 27094925 Endometrial biomarkers for the non-invasive diagnosis of endometriosis. 1 0 1
808 16034922 Long term hormone therapy for perimenopausal and postmenopausal women. 2 0 1
177 25005450 Fluid and pharmacological agents for adhesion prevention after gynaecological surgery. 2 0 1
178 14583930 Gonadotrophin-releasing hormone analogues for endometriosis: bone mineral density. 1 0 1
126 25141071 Budesonide for maintenance of remission in Crohn's disease. 4 0 1
119 30666626 Oral H1 antihistamines as 'add-on' therapy to topical treatment for eczema. 3 0 1
158 17253522 Treatment for Fisher syndrome, Bickerstaff's brainstem encephalitis and related disorders. 4 0 1
117 30343498 Leukotriene receptor antagonists for eczema. 2 0 1
159 20614424 Vaccines for preventing influenza in healthy adults. 1 0 1
160 21901713 Acupuncture for pain in endometriosis. 1 0 1
161 20238362 Anti-TNF-alpha treatment for pelvic pain associated with endometriosis. 1 0 1
150 11687068 Gangliosides for acute ischaemic stroke. 2 0 1
162 23543560 Anti-TNF-α treatment for pelvic pain associated with endometriosis. 1 0 1
164 25924805 Barrier agents for adhesion prevention after gynaecological surgery. 2 0 1
165 10796548 Barrier agents for preventing adhesions after surgery for subfertility. 1 0 1
166 27132058 Blood biomarkers for the non-invasive diagnosis of endometriosis. 2 0 1
168 27405583 Combination of the non-invasive tests for the diagnosis of endometriosis. 1 0 1
169 25072731 Continuous or extended cycle vs. cyclic use of combined hormonal contraceptives for contraception. 3 0 1
170 16034942 Continuous or extended cycle vs. cyclic use of combined oral contraceptives for contraception. 3 0 1
171 17943735 Danazol for pelvic pain associated with endometriosis. 3 0 1
172 10796484 Danazol for unexplained infertilty. 2 0 1
173 17253444 Danazol for unexplained subfertility. 1 0 1
163 23913583 Antioxidants for female subfertility. 2 0 1
174 27000311 Dietary supplements for dysmenorrhoea. 1 0 1
149 16034978 Gabapentin for acute and chronic pain. 2 0 1
147 27775812 Corticosteroids for Guillain-Barré syndrome. 14 0 1
116 30338526 Infant formulas containing hydrolysed protein for prevention of allergic disease. 8 0 1
809 27356090 Luteinising hormone releasing hormone (LHRH) agonists for the treatment of relapsed epithelial ovarian cancer. 4 0 1
747 18254021 Post-operative therapy for metacarpophalangeal arthroplasty. 2 0 1
805 24563459 Laparoscopy for diagnosing resectability of disease in patients with advanced ovarian cancer. 1 0 1
899 25267897 Pharmacological interventions for schizotypal personality disorder. 2 0 1
901 25267901 Psychological interventions for obsessive-compulsive personality disorder. 2 0 1
903 27168519 Psychosocial interventions for self-harm in adults. 1 0 1
904 24984083 Short-term psychodynamic psychotherapies for common mental disorders. 1 0 1
905 28829911 Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer. 4 0 1
820 30141832 Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations. 2 0 1
701 10796386 Injectable gold for rheumatoid arthritis. 2 0 1
819 23943232 Risk of ovarian cancer in women treated with ovarian stimulating drugs for infertility. 2 0 1
817 25991068 Poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer. 2 0 1
742 11034719 Penicillamine for treating rheumatoid arthritis. 2 0 1
743 18254117 Pharmacological agents (anti-inflammatory and analgesic) for managing symptoms in people with cystic fibrosis-related arthritis. 2 0 1
744 10796413 Pharmacotherapy for Behcet's syndrome. 2 0 1
745 28436583 Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews. 6 0 1
746 12804509 Physiotherapy interventions for shoulder pain. 4 0 1
748 19588419 Pregabalin for acute and chronic pain in adults. 3 0 1
749 27150167 Professional interventions for general practitioners on the management of musculoskeletal conditions. 3 0 1
750 30939227 Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents. 5 0 1
741 10796440 Penicillamine for rheumatoid arthritis. 2 0 1
751 23235601 Psychological therapies for the management of chronic and recurrent pain in children and adolescents. 1 0 1
754 15674912 Rofecoxib for rheumatoid arthritis. 4 0 1
900 20556783 Psychological interventions for antisocial personality disorder. 3 0 1
898 16437535 Pharmacological interventions for people with borderline personality disorder. 2 0 1
795 26801659 Effectiveness of tranexamic acid in reducing blood loss during cytoreductive surgery for advanced ovarian cancer. 2 0 1
897 25267902 Pharmacological interventions for paranoid personality disorder. 2 0 1
933 17253585 Cholecystectomy versus no cholecystectomy in patients with silent gallstones. 4 0 1
921 29757454 Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome. 15 0 1
210 25908428 Surgical versus non-surgical interventions in people with adolescent idiopathic scoliosis. 1 0 1
908 16437440 Combined chemotherapy and radiotherapy (without surgery) compared with radiotherapy alone in localized carcinoma of the esophagus. 2 0 1
907 19821327 Chinese herbal medicines for esophageal cancer. 1 0 1
906 17054195 Chemotherapy for metastatic carcinoma of the esophagus and gastro-esophageal junction. 2 0 1
880 27726123 Psychological therapies for children and adolescents exposed to trauma. 1 0 1
881 24338345 Psychological therapies for chronic post-traumatic stress disorder (PTSD) in adults. 1 0 1
882 27040448 Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder. 2 0 1
883 29975811 Psychological therapies for the treatment of mental disorders in low- and middle-income countries affected by humanitarian crises. 1 0 1
885 17636792 Psychological treatment for anxiety in people with traumatic brain injury. 3 0 1
886 17636720 Psychological treatment of post-traumatic stress disorder (PTSD). 1 0 1
887 25386846 Psychological, social and welfare interventions for psychological health and well-being of torture survivors. 1 0 1
888 19821365 Psychosocial interventions for the prevention of disability following traumatic physical injury. 1 0 1
890 22972131 Bendamustine for patients with indolent B cell lymphoid malignancies including chronic lymphocytic leukaemia. 3 0 1
891 17943799 Chemotherapy plus Rituximab versus chemotherapy alone for B-cell non-Hodgkin's lymphoma. 4 0 1
892 20166067 Antiepileptics for aggression and associated impulsivity. 6 0 1
893 22696385 Crisis interventions for people with borderline personality disorder. 2 0 1
896 25267900 Pharmacological interventions for obsessive-compulsive personality disorder. 2 0 1
755 12137705 Rofecoxib for the treatment of rheumatoid arthritis. 4 0 1
757 21901691 Screening programmes for developmental dysplasia of the hip in newborn infants. 3 0 1
758 15266426 Short-term low-dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis. 2 0 1
759 24150982 Single dose oral celecoxib for acute postoperative pain in adults. 3 0 1
723 25650566 Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and rheumatoid arthritis. 3 0 1
724 15106190 Mobile bearing vs fixed bearing prostheses for total knee arthroplasty for post-operative functional status in patients with osteoarthritis and rheumatoid arthritis. 3 0 1
725 10796420 Moderate-term, low-dose corticosteroids for rheumatoid arthritis. 2 0 1
729 25375291 Non-pharmacological interventions for preventing job loss in workers with inflammatory arthritis. 7 0 1
730 28770976 Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. 6 0 1
732 20614443 Non-surgical interventions for paediatric pes planus. 2 0 1
719 11687174 Methotrexate for treating juvenile idiopathic arthritis. 2 0 1
765 19821419 Single dose oral lornoxicam for acute postoperative pain in adults. 3 0 1
766 19821429 Single dose oral meloxicam for acute postoperative pain in adults. 2 0 1
767 19821428 Single dose oral nabumetone for acute postoperative pain in adults. 2 0 1
796 30321910 Epidermal growth factor receptor blockers for the treatment of ovarian cancer. 2 0 1
797 25198378 Evaluation of follow-up strategies for patients with epithelial ovarian cancer following completion of primary treatment. 1 0 1
798 24497188 Exenterative surgery for recurrent gynaecological malignancies. 1 0 1
799 19588362 Green tea (Camellia sinensis) for the prevention of cancer. 8 0 1
800 25101365 Hysterectomy versus hysterectomy plus oophorectomy for premenopausal women. 1 0 1
801 23740789 Interferon after surgery for women with advanced (Stage II-IV) epithelial ovarian cancer. 1 0 1
802 26747297 Interval debulking surgery for advanced epithelial ovarian cancer. 2 0 1
803 26930463 Intraoperative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses. 2 0 1
804 26755441 Intraperitoneal chemotherapy for the initial management of primary epithelial ovarian cancer. 2 0 1
722 20393970 Methotrexate monotherapy versus methotrexate combination therapy with non-biologic disease modifying anti-rheumatic drugs for rheumatoid arthritis. 2 0 1
721 27571502 Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying anti-rheumatic drugs for rheumatoid arthritis: A network meta-analysis. 3 0 1
720 24916606 Methotrexate for treating rheumatoid arthritis. 2 0 1
703 23440816 Interventions for nail psoriasis. 5 0 1
760 12804506 Single dose oral celecoxib for postoperative pain. 3 0 1
761 20393958 Single dose oral diflunisal for acute postoperative pain in adults. 3 0 1
762 19588426 Single dose oral etodolac for acute postoperative pain in adults. 3 0 1
763 24809657 Single dose oral etoricoxib for acute postoperative pain in adults. 3 0 1
752 16235383 Retention versus sacrifice of the posterior cruciate ligament in total knee replacement for treatment of osteoarthritis and rheumatoid arthritis. 3 0 1
764 15495100 Single dose oral indometacin for the treatment of acute postoperative pain. 1 0 1
740 12804484 Patient education for adults with rheumatoid arthritis. 2 0 1
734 22071805 Opioid therapy for treating rheumatoid arthritis pain. 3 0 1
705 10908464 Interventions for psoriatic arthritis. 3 0 1
718 10796399 Methotrexate for rheumatoid arthritis. 2 0 1
706 22513948 Interventions for the management of temporomandibular joint osteoarthritis. 2 0 1
708 23633379 Intra-articular glucocorticoids for acute gout. 4 0 1
709 16437446 Intra-articular steroids and splints/rest for children with juvenile idiopathic arthritis and adults with rheumatoid arthritis. 2 0 1
711 10796491 Local opinion leaders: effects on professional practice and health care outcomes. 3 0 1
713 10796462 Low level laser therapy (classes I, II and III) in the treatment of rheumatoid arthritis. 2 0 1
716 25099640 Methotrexate for induction of remission in refractory Crohn's disease. 4 0 1
717 30656673 Methotrexate for psoriatic arthritis. 5 0 1
739 14974037 Paracetamol versus nonsteroidal anti-inflammatory drugs for rheumatoid arthritis. 2 0 1
209 26423318 Surgery for scoliosis in Duchenne muscular dystrophy. 3 0 1
107 11406067 Home versus in-patient treatment for deep vein thrombosis. 2 0 1
211 22972137 Arthroplasty versus fusion in single-level cervical degenerative disc disease. 3 0 1
81 22071825 Chinese medicinal herbs for measles. 1 0 1
78 22513898 Zuclopenthixol acetate for acute schizophrenia and similar serious mental illnesses. 2 0 1
54 18425951 Paliperidone for schizophrenia. 3 0 1
55 22696377 Paliperidone palmitate for schizophrenia. 3 0 1
56 26225902 Pharmacological treatment for psychotic depression. 1 0 1
57 17054176 Pharmacological treatments for psychosis-related polydipsia. 2 0 1
58 23740790 Preventive interventions for postnatal psychosis. 1 0 1
59 25953641 Psychoeducation for siblings of people with severe mental illness. 1 0 1
60 28116752 Psychological interventions for post-traumatic stress disorder (PTSD) in people with severe mental illness. 2 0 1
61 20091600 Quetiapine versus other atypical antipsychotics for schizophrenia. 1 0 1
62 23728667 Quetiapine versus typical antipsychotic medications for schizophrenia. 4 0 1
63 29634083 Risperidone for psychosis-induced aggression or agitation (rapid tranquillisation). 3 0 1
64 21249678 Risperidone versus other atypical antipsychotics for schizophrenia. 4 0 1
65 16034864 Sertindole for schizophrenia. 4 0 1
66 19370652 Sertindole versus other atypical antipsychotics for schizophrenia. 4 0 1
68 19588393 Therapeutic interventions for symptomatic treatment in Huntington's disease. 3 0 1
69 23450559 Training to recognise the early signs of recurrence in schizophrenia. 2 0 1
70 19160215 Treatment for amphetamine psychosis. 3 0 1
72 25003310 Trifluoperazine versus low-potency first-generation antipsychotic drugs for schizophrenia. 3 0 1
73 23934958 Tripterygium wilfordii Hook F (a traditional Chinese medicine) for primary nephrotic syndrome. 14 0 1
80 11034721 Antibiotics for preventing pneumonia in children with measles. 2 0 1
96 23963793 Desferrioxamine mesylate for managing transfusional iron overload in people with transfusion-dependent thalassaemia. 4 0 1
51 26690687 Interventions for psychotic symptoms concomitant with epilepsy. 2 0 1
108 16034853 Hospital at home versus in-patient hospital care. 2 0 1
53 17943786 Open general medical wards versus specialist psychiatric units for acute psychoses. 1 0 1
83 25408540 Interventions aimed at communities to inform and/or educate about early childhood vaccination. 3 0 1
84 12519624 Interventions aimed at improving immunization rates. 3 0 1
85 28169420 Parents' and informal caregivers' views and experiences of communication about routine childhood vaccination: a synthesis of qualitative evidence. 3 0 1
86 16034918 Patient reminder and patient recall systems to improve immunization rates. 5 0 1
87 29342498 Patient reminder and recall interventions to improve immunization rates. 5 0 1
88 24687262 Post-exposure passive immunisation for preventing measles. 1 0 1
89 27580345 Routine vitamin A supplementation for the prevention of blindness due to measles infection in children. 1 0 1
90 22336803 Vaccines for measles, mumps and rubella in children. 9 0 1
93 21154399 Vitamin A supplementation for preventing morbidity and mortality in children from 6 months to 5 years of age. 3 0 1
82 27378094 Integrated management of childhood illness (IMCI) strategy for children under five. 4 0 1
94 28282701 Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. 3 0 1
97 23966105 Oral deferiprone for iron chelation in people with thalassaemia. 4 0 1
98 22592731 Pacing for drug-refractory or drug-intolerant hypertrophic cardiomyopathy. 4 0 1
99 27296775 Splenectomy for people with thalassaemia major or intermedia. 3 0 1
101 16235291 Surgical versus non-surgical management of pleural empyema. 4 0 1
103 24323411 Compression stockings for the initial treatment of varicose veins in patients without venous ulceration. 1 0 1
104 21975750 Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus conventional surgery for great saphenous vein varices. 1 0 1
106 27898181 Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for short saphenous varicose veins. 1 0 1
74 11687047 Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder. 3 0 1
75 26252640 Voxel-based morphometry for separation of schizophrenia from other types of psychosis in first episode psychosis. 2 0 1
77 29605970 Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia. 2 0 1
111 23749738 Surgery for varicose veins: use of tourniquet. 1 0 1
394 23943189 Postnatal phenobarbital for the prevention of intraventricular haemorrhage in preterm infants. 3 0 1
384 12535400 Moderately early (7-14 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. 7 0 1
395 17943755 Postnatal phenobarbital for the prevention of intraventricular hemorrhage in preterm infants. 3 0 1
372 23152207 Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome. 15 0 1
370 17943779 Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome. 5 0 1
348 15495010 Pharmacotherapy for social phobia. 3 0 1
349 20091554 Placebo interventions for all clinical conditions. 3 0 1
350 21154392 Second-generation antipsychotics for anxiety disorders. 4 0 1
351 10908557 Tricyclic drugs for depression in children and adolescents. 1 0 1
352 25922859 Acupuncture for mumps in children. 1 0 1
353 25887348 Chinese medicinal herbs for mumps. 1 0 1
354 19370695 Animal derived surfactant extract for treatment of respiratory distress syndrome. 7 0 1
355 26301526 Animal derived surfactant extract versus protein free synthetic surfactant for the prevention and treatment of respiratory distress syndrome. 16 0 1
356 27960245 Bronchodilators for the prevention and treatment of chronic lung disease in preterm infants. 4 0 1
371 12076463 Early versus delayed initiation of continuous distending pressure for respiratory distress syndrome in preterm infants. 4 0 1
359 10908543 Continuous distending airway pressure for respiratory distress syndrome in preterm infants. 1 0 1
361 12076445 Continuous distending pressure for respiratory distress syndrome in preterm infants. 2 0 1
928 12076457 Interventions for preventing eating disorders in children and adolescents. 2 0 1
362 30701528 Continuous positive airway pressure (CPAP) for acute bronchiolitis in children. 2 0 1
393 30548249 Point-of-care ultrasonography for diagnosing thoracoabdominal injuries in patients with blunt trauma. 1 0 1
392 26436599 Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery. 2 0 1
390 15846639 Neuromuscular paralysis for newborn infants receiving mechanical ventilation. 2 0 1
379 28141899 Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit. 2 0 1
231 29620793 Antidepressants versus placebo for panic disorder in adults. 2 0 1
233 25268297 Azapirones versus placebo for panic disorder in adults. 7 0 1
234 30921478 Benzodiazepines versus placebo for panic disorder in adults. 2 0 1
374 26945780 Frequency of endotracheal suctioning for the prevention of respiratory morbidity in ventilated newborns. 3 0 1
375 26899543 High flow nasal cannula for respiratory support in preterm infants. 1 0 1
376 28555461 High-flow nasal cannulae for respiratory support in adult intensive care patients. 4 0 1
377 29985541 Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of stay and lung injury in adults without acute lung injury. 1 0 1
378 26641378 Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of stay and lung injury in patients without acute lung injury. 1 0 1
380 21735428 Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants with or at risk of respiratory distress syndrome. 15 0 1
389 29077984 Neurally adjusted ventilatory assist compared to other forms of triggered ventilation for neonatal respiratory support. 4 0 1
381 23633311 Lung lavage for meconium aspiration syndrome in newborn infants. 15 0 1
382 10796577 Lung volume reduction surgery for diffuse emphysema. 1 0 1
373 11279696 Endotracheal intubation at birth for preventing morbidity and mortality in vigorous, meconium-stained infants born at term. 4 0 1
383 12519575 Mechanical ventilation for newborn infants with respiratory failure due to pulmonary disease. 3 0 1
385 10796305 Multiple versus single dose natural surfactant extract for severe neonatal respiratory distress syndrome. 5 0 1
386 19160177 Multiple versus single doses of exogenous surfactant for the prevention or treatment of neonatal respiratory distress syndrome. 9 0 1
387 11405951 Natural surfactant extract versus synthetic surfactant for neonatal respiratory distress syndrome. 7 0 1
388 30707441 Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn. 1 0 1
52 20238348 Olanzapine versus other atypical antipsychotics for schizophrenia. 2 0 1
15 17636744 Antipsychotic medication for childhood-onset schizophrenia. 3 0 1
212 21735434 Botulinum toxin for subacute/chronic neck pain. 2 0 1
183 21069706 Interventions for women with endometrioma prior to assisted reproductive technology. 1 0 1
185 19821276 Laparoscopic surgery for pelvic pain associated with endometriosis. 1 0 1
186 20091519 Laparoscopic surgery for subfertility associated with endometriosis. 1 0 1
187 23440798 Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery. 1 0 1
188 10908491 Liquid and fluid agents for preventing adhesions after surgery for subfertility. 2 0 1
189 16437491 Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. 2 0 1
190 10796731 Modern combined oral contraceptives for pain associated with endometriosis. 5 0 1
191 16235379 Non-steroidal anti-inflammatory drugs for pain in women with endometriosis. 2 0 1
192 24595586 Non-surgical interventions for the management of chronic pelvic pain. 4 0 1
193 28114727 Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. 2 0 1
194 29786828 Oral contraceptives for pain associated with endometriosis. 2 0 1
195 17636607 Ovulation suppression for endometriosis. 1 0 1
197 19588441 Pentoxifylline versus medical therapies for subfertile women with endometriosis. 1 0 1
198 15266496 Pre and post operative medical therapy for endometriosis surgery. 2 0 1
199 16235288 Surgical interruption of pelvic nerve pathways for primary and secondary dysmenorrhoea. 2 0 1
200 26695425 Urinary biomarkers for the non-invasive diagnosis of endometriosis. 1 0 1
201 23235619 Adjuvant antiviral therapy for recurrent respiratory papillomatosis. 3 0 1
202 27643712 Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children. 3 0 1
114 30376593 Gamma aminobutyric acid (GABA) receptor agonists for acute stroke. 5 0 1
230 24163112 Behavioral interventions for improving condom use for dual protection. 2 0 1
184 24696265 Laparoscopic surgery for endometriosis. 1 0 1
182 11034686 Interventions for treating chronic pelvic pain in women. 5 0 1
24 25314586 Cannabis and schizophrenia. 2 0 1
180 19160262 Hormone therapy for endometriosis and surgical menopause. 1 0 1
213 20091597 Chinese herbal medicine for chronic neck pain due to cervical degenerative disc disease. 3 0 1
214 23979926 Electrotherapy for neck pain. 2 0 1
215 25629215 Exercises for mechanical neck disorders. 2 0 1
216 24379134 Immunotherapy for idiopathic lumbosacral plexopathy. 3 0 1
207 20166095 Physical examination for lumbar radiculopathy due to disc herniation in patients with low-back pain. 2 0 1
217 18646151 Mechanical traction for neck pain with or without radiculopathy. 1 0 1
219 28530786 Morphine for chronic neuropathic pain in adults. 3 0 1
220 29199767 Oxcarbazepine for neuropathic pain. 5 0 1
221 19160247 Patient education for neck pain with or without radiculopathy. 1 0 1
222 22419306 Patient education for neck pain. 2 0 1
223 11686992 Surgery for cervical radiculomyelopathy. 3 0 1
225 23996081 Topiramate for neuropathic pain and fibromyalgia in adults. 3 0 1
226 17253498 Recombinant growth hormone for children and adolescents with Turner syndrome. 1 0 1
227 12917993 Recombinant growth hormone in children and adolescents with Turner syndrome. 1 0 1
228 19588414 Treatment for idiopathic and hereditary neuralgic amyotrophy (brachial neuritis). 4 0 1
218 25184502 Minimally invasive discectomy versus microdiscectomy/open discectomy for symptomatic lumbar disc herniation. 2 0 1
206 27572719 Pharmacological treatments for Friedreich ataxia. 3 0 1
205 22895967 Exercises for adolescent idiopathic scoliosis. 1 0 1
203 22513953 Antioxidants and other pharmacological treatments for Friedreich ataxia. 3 0 1
113 29125628 Genomics-based non-invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women. 6 0 1
110 26477632 Interventions for varicose veins and leg oedema in pregnancy. 2 0 1
29 24190251 Collaborative care approaches for people with severe mental illness. 2 0 1
30 10908541 Cyclophosphamide versus methylprednisolone for the treatment of neuropsychiatric involvement in systemic lupus erythematosus. 7 0 1
2 27977064 Anti-vascular endothelial growth factor for choroidal neovascularisation in people with pathological myopia. 6 0 1
3 24937100 Excimer laser refractive surgery versus phakic intraocular lenses for the correction of moderate to high myopia. 3 0 1
5 16235380 Laser photocoagulation for choroidal neovascularisation in pathologic myopia. 1 0 1
6 23440799 Laser-assisted in-situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia. 1 0 1
8 26899152 Laser-assisted subepithelial keratectomy (LASEK) versus photorefractive keratectomy (PRK) for correction of myopia. 2 0 1
9 16625626 Photorefractive keratectomy (PRK) versus laser-assisted in-situ keratomileusis (LASIK) for myopia. 1 0 1
11 12076447 Antidepressants for people with both schizophrenia and depression. 2 0 1
12 26725721 Antiglucocorticoid and related treatments for psychosis. 2 0 1
13 12804499 Antipsychotic drug treatment for elderly people with late-onset schizophrenia. 3 0 1
26 11279762 Clotiapine for acute psychotic illnesses. 4 0 1
14 15106251 Antipsychotic drugs for non-affective psychosis during pregnancy and postpartum. 1 0 1
16 29308601 Aripiprazole (intramuscular) for psychosis-induced aggression or agitation (rapid tranquillisation). 1 0 1
17 21833956 Aripiprazole versus placebo for schizophrenia. 3 0 1
18 18646161 Aripiprazole versus typical antipsychotic drugs for schizophrenia. 2 0 1
19 18254107 Aripiprazole versus typicals for schizophrenia. 2 0 1
20 24129841 Atypical antipsychotics for psychosis in adolescents. 2 0 1
21 16235313 Benzodiazepines alone or in combination with antipsychotic drugs for acute psychosis. 2 0 1
22 29219171 Benzodiazepines for psychosis-induced aggression or agitation. 1 0 1
23 23152236 Benzodiazepines for schizophrenia. 2 0 1
25 20393959 Chlorpromazine for psychosis induced aggression or agitation. 3 0 1
27 26397173 Clozapine for psychotic disorders in adults with intellectual disabilities. 2 0 1
50 23076932 Information and communication technology in patient education and support for people with schizophrenia. 2 0 1
39 16625545 Educational games for mental health professionals. 1 0 1
31 16625558 Cyclophosphamide versus methylprednisolone for treating neuropsychiatric involvement in systemic lupus erythematosus. 5 0 1
32 30019748 De-escalation techniques for managing non-psychosis induced aggression in adults. 1 0 1
33 28368091 De-escalation techniques for psychosis-induced aggression or agitation. 1 0 1
34 14584007 Depot risperidone for schizophrenia. 2 0 1
35 27007216 Dietary advice for people with schizophrenia. 3 0 1
36 15495037 Droperidol for acute psychosis. 3 0 1
37 27976370 Droperidol for psychosis-induced aggression or agitation. 5 0 1
28 26488686 Cognitive behavioural therapy (brief versus standard duration) for schizophrenia. 2 0 1
41 25879096 First rank symptoms for schizophrenia. 2 0 1
40 16235377 Estrogen for schizophrenia. 2 0 1
42 25177834 Flupenthixol versus low-potency first-generation antipsychotic drugs for schizophrenia. 4 0 1
43 25087165 Fluphenazine versus low-potency first-generation antipsychotic drugs for schizophrenia. 4 0 1
44 27889922 Haloperidol for long-term aggression in psychosis. 1 0 1
45 28758203 Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). 2 0 1
46 15654706 Haloperidol plus promethazine for psychosis induced aggression. 1 0 1
47 27885664 Haloperidol plus promethazine for psychosis-induced aggression. 2 0 1
48 25592299 Haloperidol versus first-generation antipsychotics for the treatment of schizophrenia and other psychotic disorders. 2 0 1
49 25007358 Haloperidol versus low-potency first-generation antipsychotic drugs for schizophrenia. 2 0 1
930 15266434 Psychotherapy for bulimia nervosa and binging. 3 0 1
584 22161372 Naftidrofuryl for dementia. 3 0 1
927 30663033 Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders. 3 0 1
616 30520514 Traditional Chinese herbal medicine for vascular dementia. 2 0 1
617 12917999 Transcutaneous electrical nerve stimulation (TENS) for dementia. 3 0 1
620 30293233 Valproate preparations for agitation in dementia. 1 0 1
621 15106227 Valproic acid for agitation in dementia. 1 0 1
622 12535455 Vinpocetine for cognitive impairment and dementia. 4 0 1
623 30383288 Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment. 2 0 1
625 17443586 Yizhi capsule for vascular dementia. 3 0 1
626 15495123 Zhiling decoction for vascular dementia. 2 0 1
630 16437479 Acetaminophen for osteoarthritis. 2 0 1
631 12137715 Acupuncture and electroacupuncture for the treatment of RA. 2 0 1
632 16235342 Acupuncture and electroacupuncture for the treatment of rheumatoid arthritis. 2 0 1
618 15495135 Trazodone for agitation in dementia. 3 0 1
633 15846753 Acupuncture for shoulder pain. 6 0 1
603 26102272 Regional cerebral blood flow single photon emission computed tomography for detection of Frontotemporal dementia in people with suspected dementia. 3 0 1
601 24449085 Psychological treatments for depression and anxiety in dementia and mild cognitive impairment. 1 0 1
576 30106471 Mindfulness-based stress reduction for family carers of people with dementia. 1 0 1
577 25922857 Mini-Cog for the diagnosis of Alzheimer's disease dementia and other dementias within a community setting. 2 0 1
578 29470861 Mini-Cog for the diagnosis of Alzheimer's disease dementia and other dementias within a primary care setting. 3 0 1
580 30251253 Modifying the consistency of food and fluids for swallowing difficulties in dementia. 2 0 1
581 10908486 Music therapy for dementia symptoms. 1 0 1
605 24435941 Respite care for people with dementia and their carers. 1 0 1
615 11686961 Thioridazine for dementia. 1 0 1
3068 27783843 Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease. 5 0 1
614 16625595 The effects of blood pressure lowering on development of cognitive impairment and dementia in patients without apparent prior cerebrovascular disease. 4 0 1
3070 17636818 Endoscopic retrograde cholangiopancreaticography with or without stenting in patients with pancreaticobiliary malignancy, prior to surgery. 3 0 1
3071 29934987 Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery. 1 0 1
3072 17253517 Ileostomy or colostomy for temporary decompression of colorectal anastomosis. 3 0 1
3073 30160300 Immunonutrition for patients undergoing surgery for head and neck cancer. 3 0 1
3074 22972115 Interposition vein cuff for infragenicular prosthetic bypass graft. 1 0 1
3075 29106711 Interventions for treating central venous haemodialysis catheter malfunction. 3 0 1
3076 30113083 Interventions for treating oro-antral communications and fistulae due to dental procedures. 1 0 1
3077 30480758 Omega-3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease. 6 0 1
3078 28898386 Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction for the prevention of postoperative pancreatic fistula following pancreaticoduodenectomy. 2 0 1
3055 28079254 Pharmacological treatment of vascular risk factors for reducing mortality and cardiovascular events in patients with abdominal aortic aneurysm. 3 0 1
3655 14583994 Combined corticosteroid and longacting beta-agonist in one inhaler for chronic obstructive pulmonary disease. 1 0 1
1846 22336783 Effectiveness of organisational infrastructures to promote evidence-based nursing practice. 1 0 1
1843 30537080 Dressings and topical agents for preventing pressure ulcers. 1 0 1
607 28418586 Simulated presence therapy for dementia. 2 0 1
608 12519587 Snoezelen for dementia. 2 0 1
609 19821370 Special care units for dementia individuals with behavioural problems. 2 0 1
610 27610945 Statin withdrawal in people with dementia. 1 0 1
611 26727124 Statins for the prevention of dementia. 4 0 1
613 10796545 Support for carers of people with Alzheimer's type dementia. 2 0 1
582 15266489 Music therapy for people with dementia. 1 0 1
585 25177209 Neuropsychological tests for the diagnosis of Alzheimer's disease dementia and other dementias: a generic protocol for cross-sectional and delayed-verification studies. 2 0 1
586 12137606 Nimodipine for primary degenerative, mixed and vascular dementia. 5 0 1
602 11034699 Reality orientation for dementia. 1 0 1
683 10796342 Dynamic exercise therapy for rheumatoid arthritis. 2 0 1
668 12535501 Corticosteroid injections for shoulder pain. 4 0 1
684 20091657 Effect of cyclosporine on blood pressure. 4 0 1
688 30303519 Eszopiclone for insomnia. 4 0 1
689 23728649 Etanercept for the treatment of rheumatoid arthritis. 2 0 1
690 30063798 Exercise for rheumatoid arthritis of the hand. 2 0 1
691 18425929 Exercise therapy in juvenile idiopathic arthritis. 2 0 1
692 23152264 Febuxostat for treating chronic gout. 2 0 1
694 24151647 Folic acid supplementation for rheumatoid arthritis patients on methotrexate: the good gets better. 2 0 1
695 15846645 Glucosamine therapy for treating osteoarthritis. 2 0 1
697 11279783 Herbal therapy for treating osteoarthritis. 2 0 1
698 21328257 Herbal therapy for treating rheumatoid arthritis. 2 0 1
685 17253590 Effects of glucocorticoids on radiological progression in rheumatoid arthritis. 2 0 1
667 12804511 Continuous passive motion following total knee arthroplasty. 3 0 1
666 24500904 Continuous passive motion following total knee arthroplasty in people with arthritis. 1 0 1
665 21975788 Combination therapy for pain management in inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis). 6 0 1
639 22071859 Antidepressants for pain management in rheumatoid arthritis. 2 0 1
640 10796401 Antimalarials for rheumatoid arthritis. 2 0 1
642 19821383 Assistive technology for rheumatoid arthritis. 2 0 1
679 22972107 Disease modifying anti-rheumatic drugs in people with cystic fibrosis-related arthritis. 4 0 1
678 11034708 Dietary marine fatty acids (fish oil) for asthma. 2 0 1
677 12137622 Dietary marine fatty acids (fish oil) for asthma in adults and children. 2 0 1
599 18843698 Procaine treatments for cognition and dementia. 1 0 1
587 17253573 Non-pharmacological interventions for wandering of people with dementia in the domestic setting. 1 0 1
589 16437528 Omega 3 fatty acid for the prevention of dementia. 1 0 1
591 25972091 Opioids for agitation in dementia. 1 0 1
593 18254118 Personal assistance for older adults (65+) without dementia. 1 0 1
594 29438597 Personally tailored activities for improving psychosocial outcomes for people with dementia in long-term care. 1 0 1
596 18646158 Physical activity programs for persons with dementia. 1 0 1
597 11405971 Piracetam for dementia or cognitive impairment. 3 0 1
598 24913723 Plasma and cerebrospinal fluid amyloid beta for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). 2 0 1
600 12804440 Propentofylline for dementia. 3 0 1
674 11034702 Cyclophosphamide for treating rheumatoid arthritis. 7 0 1
588 22696350 Omega 3 fatty acid for the prevention of cognitive decline and dementia. 1 0 1
636 19160248 Anakinra for rheumatoid arthritis. 2 0 1
637 10796384 Analgesia and non-aspirin, non-steroidal anti-inflammatory drugs for osteoarthritis of the hip. 3 0 1
638 26798057 Anti-inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis-related arthritis. 3 0 1
669 30480764 Corticosteroids for septic arthritis in children. 2 0 1
671 18646168 Custom-made foot orthoses for the treatment of foot pain. 4 0 1
672 29297205 Cyclophosphamide for connective tissue disease-associated interstitial lung disease. 13 0 1
673 10796419 Cyclophosphamide for rheumatoid arthritis. 7 0 1
3069 29099149 Closure methods for laparotomy incisions for preventing incisional hernias and other wound complications. 1 0 1
3067 28386958 Amylase in drain fluid for the diagnosis of pancreatic leak in post-pancreatic resection. 1 0 1
644 14974011 Azathioprine as an oral corticosteroid sparing agent for asthma. 4 0 1
3048 22336843 Intraoperative mild hypothermia for postoperative neurological deficits in intracranial aneurysm patients. 3 0 1
3050 27541335 Intravenous heparin during ruptured abdominal aortic aneurysmal repair. 3 0 1
3051 28471523 Laparoscopic surgery for elective abdominal aortic aneurysm repair. 3 0 1
3052 26184395 Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts. 4 0 1
3041 16235314 Endovascular coiling versus neurosurgical clipping for patients with aneurysmal subarachnoid haemorrhage. 2 0 1
3028 29543980 Macrolide antibiotics for bronchiectasis. 6 0 1
3027 24173771 Lactose avoidance for young children with acute diarrhoea. 2 0 1
3025 23076931 Antibiotics for treating human brucellosis. 1 0 1
2998 23440843 Selenium supplementation for the primary prevention of cardiovascular disease. 2 0 1
2999 27819748 Topical antibiotics for preventing surgical site infection in wounds healing by primary intention. 3 0 1
3000 16235358 Topical vitamin A, or its derivatives, for treating and preventing napkin dermatitis in infants. 1 0 1
3002 26513427 Psychological therapies for the management of chronic neuropathic pain in adults. 1 0 1
3003 20614450 Incision and drainage of perianal abscess with or without treatment of anal fistula. 2 0 1
3004 20464741 Surgical intervention for anorectal fistula. 2 0 1
3006 22071803 Operative procedures for fissure in ano. 1 0 1
3007 23235673 Interventions for anal canal intraepithelial neoplasia. 2 0 1
3008 29178444 Alemtuzumab versus interferon beta 1a for relapsing-remitting multiple sclerosis. 2 0 1
3009 25900414 Dimethyl fumarate for multiple sclerosis. 4 0 1
3012 18843696 Antimotility agents for chronic diarrhoea in people with HIV/AIDS. 2 0 1
3013 19588378 Family support for reducing morbidity and mortality in people with HIV/AIDS. 2 0 1
3049 27000210 Intraoperative mild hypothermia for postoperative neurological deficits in people with intracranial aneurysm. 3 0 1
3047 25173678 Endovascular versus open repair of asymptomatic popliteal artery aneurysm. 1 0 1
3066 28598495 Ultrasonography for endoleak detection after endoluminal abdominal aortic aneurysm repair. 3 0 1
3046 23152237 Endovascular versus conventional medical treatment for uncomplicated chronic type B aortic dissection. 1 0 1
364 11406065 Cromolyn sodium for the prevention of chronic lung disease in preterm infants. 2 0 1
3186 21249694 Acupuncture for cancer pain in adults. 1 0 1
3107 14583980 Exercise therapy for patellofemoral pain syndrome. 5 0 1
3106 27283591 Electrotherapy modalities for rotator cuff disease. 4 0 1
3105 12519601 Deep transverse friction massage for treating tendinitis. 2 0 1
3104 25380079 Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis. 2 0 1
3030 22161412 Probiotics for maintenance of remission in ulcerative colitis. 9 0 1
3031 14973994 Rotavirus vaccine for preventing diarrhoea. 1 0 1
3032 18646177 Tacrolimus (FK506) for induction of remission in refractory ulcerative colitis. 4 0 1
3033 27012320 Vitamin A supplementation for postpartum women. 1 0 1
3034 23990381 Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage. 2 0 1
3035 10796337 Calcium antagonists for aneurysmal subarachnoid haemorrhage. 2 0 1
3037 29897100 Controlled hypotension versus normotensive resuscitation strategy for people with ruptured abdominal aortic aneurysm. 5 0 1
3038 22419329 Distal aortic perfusion during thoracoabdominal aneurysm repair for prevention of paraplegia. 3 0 1
3039 14583985 Early extubation for adult cardiac surgical patients. 2 0 1
3029 16856044 Oral versus intravenous rehydration for treating dehydration due to gastroenteritis in children. 5 0 1
3040 23728673 Early versus delayed mobilisation for aneurysmal subarachnoid haemorrhage. 1 0 1
3042 30110521 Endovascular coiling versus neurosurgical clipping for people with aneurysmal subarachnoid haemorrhage. 2 0 1
3044 25879695 Endovascular repair versus open repair for inflammatory abdominal aortic aneurysms. 3 0 1
3014 20091575 Home-based care for reducing morbidity and mortality in people infected with HIV/AIDS. 3 0 1
3015 23450564 Interventions for squamous cell carcinoma of the conjunctiva in HIV-infected individuals. 4 0 1
3016 21154354 Micronutrient supplementation in children and adults with HIV infection. 1 0 1
3017 20556793 Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection. 1 0 1
3096 30480754 Moxibustion for alleviating side effects of chemotherapy or radiotherapy in people with cancer. 2 0 1
3097 15846660 Single agent versus combination chemotherapy for metastatic breast cancer. 1 0 1
3098 26845108 The role of iron in the management of chemotherapy-induced anemia in cancer patients receiving erythropoiesis-stimulating agents. 3 0 1
3099 30776082 Transcatheter arterial chemoembolisation followed by three-dimensional conformal radiotherapy versus transcatheter arterial chemoembolisation alone for primary hepatocellular carcinoma in adults. 3 0 1
3100 18646142 Intervention for childhood apraxia of speech. 1 0 1
3101 16235357 Interventions for apraxia of speech following stroke. 2 0 1
3103 21491397 Non-pharmacological interventions for perceptual disorders following stroke and other adult-acquired, non-progressive brain injury. 2 0 1
3093 10796557 Azathioprine or 6-mercaptopurine for inducing remission of Crohn's disease. 5 0 1
3081 26418347 Preoperative vascular access evaluation for haemodialysis patients. 3 0 1
3080 28589547 Preoperative exercise training for patients with non-small cell lung cancer. 4 0 1
3079 26741512 Pre-emptive correction for haemodialysis arteriovenous access stenosis. 2 0 1
3057 26402164 Stent graft types for endovascular repair of abdominal aortic aneurysms. 3 0 1
3058 26402041 Stent graft types for endovascular repair of thoracic aortic aneurysms. 1 0 1
3059 22592728 Stent placement versus surgery for coarctation of the thoracic aorta. 2 0 1
3061 27265222 Thoracic stent graft versus surgery for thoracic aneurysm. 4 0 1
3062 11405999 Timing of surgery for aneurysmal subarachnoid haemorrhage. 2 0 1
3063 24578199 Totally percutaneous versus standard femoral artery access for elective bifurcated abdominal endovascular aneurysm repair. 3 0 1
3064 28221665 Totally percutaneous versus surgical cut-down femoral artery access for elective bifurcated abdominal endovascular aneurysm repair. 3 0 1
3065 26848807 Transperitoneal versus retroperitoneal approach for elective open abdominal aortic aneurysm repair. 3 0 1
3095 23633324 Chinese herbal medicines for induction of remission in advanced or late gastric cancer. 1 0 1
3094 26517527 Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease. 3 0 1
3092 16856005 Addition of drug/s to a chemotherapy regimen for metastatic breast cancer. 1 0 1
3056 17443519 Screening for abdominal aortic aneurysm. 3 0 1
3018 28291302 Psychosocial group interventions to improve psychological well-being in adults living with HIV. 1 0 1
3020 25072817 Structural and community-level interventions for increasing condom use to prevent the transmission of HIV and other sexually transmitted infections. 3 0 1
3021 24980859 Task shifting from doctors to non-doctors for initiation and maintenance of antiretroviral therapy. 2 0 1
3022 23728688 Telephone delivered interventions for preventing HIV infection in HIV-negative persons. 1 0 1
3023 21975747 Treatment for anemia in people with AIDS. 3 0 1
3053 19821267 Patch angioplasty versus primary closure for carotid endarterectomy. 1 0 1
3216 16034856 Laparoscopic "drilling" by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. 3 0 1
3054 15106141 Patches of different types for carotid patch angioplasty. 1 0 1
3083 27905673 Single versus multiple visits for endodontic treatment of permanent teeth. 2 0 1
3082 29928755 Prophylactic abdominal drainage for pancreatic surgery. 1 0 1
3084 23633353 Somatostatin analogues for pancreatic surgery. 1 0 1
3085 26544925 Stapler versus scalpel resection followed by hand-sewn closure of the pancreatic remnant for distal pancreatectomy. 2 0 1
3086 27153248 Stents for the prevention of pancreatic fistula following pancreaticoduodenectomy. 2 0 1
3087 26820670 Surgery versus medical therapy for heavy menstrual bleeding. 1 0 1
3088 26264829 Surgical approach to hysterectomy for benign gynaecological disease. 2 0 1
3089 18254120 Tumor necrosis factor-alpha antibody for maintenance of remission in Crohn's disease. 2 0 1
3090 29756637 Withdrawal of immunosuppressant or biologic therapy for patients with quiescent Crohn's disease. 4 0 1
3091 16625617 Drugs for treating paracoccidioidomycosis. 1 0 1
643 10796461 Auranofin versus placebo in rheumatoid arthritis. 2 0 1
645 10796441 Azathioprine for rheumatoid arthritis. 2 0 1
926 14583998 Individual psychotherapy in the outpatient treatment of adults with anorexia nervosa. 2 0 1
454 20238328 Non-surgical interventions for eosinophilic esophagitis. 6 0 1
702 28273330 Interventions for hereditary haemochromatosis: an attempted network meta-analysis. 10 0 1
849 17054150 Haemophilus influenzae oral whole cell vaccination for preventing acute exacerbations of chronic bronchitis. 1 0 1
850 23543575 Inhaled corticosteroids for subacute and chronic cough in adults. 2 0 1
851 22895919 Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease. 2 0 1
853 24718923 Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. 4 0 1
854 18646148 Pelargonium sidoides extract for acute respiratory tract infections. 3 0 1
855 24146345 Pelargonium sidoides extract for treating acute respiratory tract infections. 3 0 1
856 12535510 Prophylactic antibiotic therapy for chronic bronchitis. 1 0 1
857 28322440 Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease. 3 0 1
858 23728681 Tacrolimus versus cyclosporin as primary immunosuppression for lung transplant recipients. 4 0 1
847 10796676 Haemophilus influenzae oral vaccination against acute bronchitis. 1 0 1
859 27931077 Antibiotics for the neurological complications of Lyme disease. 3 0 1
863 10796724 Brief psychological interventions ("debriefing") for trauma-related symptoms and the prevention of post traumatic stress disorder. 1 0 1
864 22592679 Cognitive-behavioural interventions for children who have been sexually abused. 1 0 1
866 25858181 Debriefing interventions for the prevention of psychological trauma in women following childbirth. 1 0 1
867 25488158 Diaries for recovery from critical illness. 1 0 1
868 20238359 Early psychological interventions to treat acute traumatic stress symptoms. 1 0 1
869 30388297 Follow-up services for improving long-term outcomes in intensive care unit (ICU) survivors. 3 0 1
870 30316199 Information or education interventions for adult intensive care unit (ICU) patients and their carers. 1 0 1
700 12137712 Infliximab for the treatment of rheumatoid arthritis. 2 0 1
571 15106228 Light therapy for managing sleep, behaviour, and mood disturbances in dementia. 1 0 1
539 30864747 Computerised cognitive training for preventing dementia in people with mild cognitive impairment. 3 0 1
538 30909318 Cognitive training for people with mild to moderate dementia. 1 0 1
513 29164602 18F PET with flutemetamol for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). 3 0 1
514 12804452 Acetyl-L-carnitine for dementia. 2 0 1
515 17443563 Acupuncture for vascular dementia. 2 0 1
516 30828783 AD-8 for detection of dementia across a variety of healthcare settings. 1 0 1
517 18646159 Adjunctive therapies for AIDS dementia complex. 3 0 1
518 21412915 Almitrine-Raubasine combination for dementia. 2 0 1
519 14974062 Alpha lipoic acid for dementia. 2 0 1
521 12917949 Aroma therapy for dementia. 1 0 1
523 30215847 Art therapy for people with dementia. 1 0 1
524 11034710 Aspirin for vascular dementia. 2 0 1
525 28602027 Assistive technology for memory support in dementia. 1 0 1
526 19821318 Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. 4 0 1
527 30024023 Blood pressure-lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients with a history of stroke or transient ischaemic attack. 2 0 1
529 25560977 Case management approaches to home support for people with dementia. 1 0 1
530 23440834 Cerebrolysin for vascular dementia. 3 0 1
532 12917981 Cholinesterase inhibitors for dementia with Lewy bodies. 2 0 1
533 16437494 Cholinesterase inhibitors for Parkinson's disease dementia. 2 0 1
535 14583963 Cognitive rehabilitation and cognitive training for early-stage Alzheimer's disease and vascular dementia. 3 0 1
537 23740535 Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia. 3 0 1
871 30550643 Internet-based cognitive and behavioural therapies for post-traumatic stress disorder (PTSD) in adults. 1 0 1
872 24018460 Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults. 1 0 1
861 23633345 Interventions for acute internal hordeolum. 2 0 1
874 26439374 Non-pharmacological interventions for sleep promotion in the intensive care unit. 2 0 1
831 27092708 Eradication therapy for peptic ulcer disease in Helicobacter pylori-positive people. 2 0 1
875 24249541 Non-specialist health worker interventions for the care of mental, neurological and substance-abuse disorders in low- and middle-income countries. 2 0 1
877 25601826 Pharmacotherapy for anxiety and comorbid alcohol use disorders. 3 0 1
878 16437445 Pharmacotherapy for post traumatic stress disorder (PTSD). 1 0 1
910 23152259 Omentoplasty for esophagogastrostomy after esophagectomy. 1 0 1
911 25988291 Preoperative chemotherapy for resectable thoracic esophageal cancer. 3 0 1
912 16235286 Preoperative radiotherapy for esophageal carcinoma. 2 0 1
913 10796823 Preoperative radiotherapy for esophageal carcinoma. Oeosphageal Cancer Collaborative Group. 2 0 1
914 12519549 Allopurinol for chronic prostatitis. 2 0 1
915 30682211 Antibiotics for treating urogenital Chlamydia trachomatis infection in men and non-pregnant women. 5 0 1
916 23934982 Antimicrobial therapy for chronic bacterial prostatitis. 2 0 1
917 25504418 Antioxidants for male subfertility. 1 0 1
919 11279750 Interventions for chronic abacterial prostatitis. 3 0 1
909 17443549 Medicinal herbs for esophageal cancer. 2 0 1
920 22071840 Lycopene for the prevention of prostate cancer. 4 0 1
922 22895982 Pregabalin for chronic prostatitis. 1 0 1
923 16437485 Antidepressants for anorexia nervosa. 2 0 1
924 30320438 Family therapy approaches for anorexia nervosa. 2 0 1
925 26212713 Individual psychological therapy in the outpatient treatment of adults with anorexia nervosa. 2 0 1
843 22336804 Chinese medicinal herbs for acute bronchitis. 1 0 1
841 21735384 Beta2-agonists for acute bronchitis. 2 0 1
840 25749735 Azithromycin for acute lower respiratory tract infections. 1 0 1
827 17443601 Epinephrine injection versus epinephrine injection and a second endoscopic method in high risk bleeding ulcers. 1 0 1
846 10796542 Educational outreach visits: effects on professional practice and health care outcomes. 2 0 1
844 23633320 Delayed antibiotics for respiratory infections. 3 0 1
821 22258988 Robotic assisted surgery for gynaecological cancer. 3 0 1
822 23450588 Surgical cytoreduction for recurrent epithelial ovarian cancer. 1 0 1
823 20238312 Tamoxifen for relapse of ovarian cancer. 2 0 1
824 18425923 Topotecan for ovarian cancer. 1 0 1
825 21491400 Ultra-radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer. 1 0 1
826 28301676 Deprescribing versus continuation of chronic proton pump inhibitor use in adults. 6 0 1
828 25308912 Epinephrine injection versus epinephrine injection and a second endoscopic method in high-risk bleeding ulcers. 1 0 1
837 22419331 Airway clearance techniques for chronic obstructive pulmonary disease. 2 0 1
829 16625554 Eradication of Helicobacter pylori for non-ulcer dyspepsia. 2 0 1
845 15495108 Delayed antibiotics for symptoms and complications of respiratory infections. 5 0 1
830 16625592 Eradication therapy for peptic ulcer disease in Helicobacter pylori positive patients. 2 0 1
832 15106235 H. pylori eradication therapy vs. antisecretory non-eradication therapy (with or without long-term maintenance antisecretory therapy) for the prevention of recurrent bleeding from peptic ulcer. 1 0 1
833 23450555 Laparoscopic repair for perforated peptic ulcer disease. 2 0 1
834 26852297 Periodontal therapy as adjunctive treatment for gastric Helicobacter pylori infection. 2 0 1
835 12535398 Vaginal misoprostol for cervical ripening and induction of labour. 1 0 1
836 23728642 Acetylcysteine and carbocysteine for acute upper and lower respiratory tract infections in paediatric patients without chronic broncho-pulmonary disease. 1 0 1
512 29164603 18F PET with florbetapir for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). 3 0 1
540 28328043 CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). 3 0 1
646 11034720 Azathioprine for treating rheumatoid arthritis. 2 0 1
487 27841441 Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients. 2 0 1
489 28950030 Compression therapy for prevention of post-thrombotic syndrome. 16 0 1
490 14584008 Compression therapy for treating stage I and II (Widmer) post-thrombotic syndrome. 2 0 1
491 18843687 Interventions for preventing venous thromboembolism in adults undergoing knee arthroscopy. 2 0 1
492 14974060 Non-pharmaceutical measures for prevention of post-thrombotic syndrome. 3 0 1
481 25013384 Comparison of intraocular lens types for cataract surgery in eyes with uveitis. 2 0 1
493 23857562 Once versus twice daily low molecular weight heparin for the initial treatment of venous thromboembolism. 1 0 1
495 27814432 Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis. 5 0 1
496 30406639 Rutosides for prevention of post-thrombotic syndrome. 16 0 1
497 30406640 Rutosides for treatment of post-thrombotic syndrome. 16 0 1
498 24026801 Systemic treatments for the prevention of venous thrombo-embolic events in paediatric cancer patients with tunnelled central venous catheters. 3 0 1
499 27830895 Thrombolysis for acute deep vein thrombosis. 5 0 1
500 29226949 Thrombolysis for acute upper extremity deep vein thrombosis. 5 0 1
503 22161424 Topical interventions for genital lichen sclerosus. 3 0 1
504 27092951 A comparison of different antibiotic regimens for the treatment of infective endocarditis. 2 0 1
506 12918006 Antibiotics to prevent complications following dental implant treatment. 2 0 1
494 26123214 Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of deep vein thrombosis. 4 0 1
507 24395715 Beta lactam antibiotic monotherapy versus beta lactam-aminoglycoside antibiotic combination therapy for sepsis. 1 0 1
480 11869630 Antibiotics versus control for toxoplasma retinochoroiditis. 1 0 1
478 30562409 Anti-tumour necrosis factor biological therapies for the treatment of uveitic macular oedema (UMO) for non-infectious uveitis. 1 0 1
488 29040800 Ocriplasmin for symptomatic vitreomacular adhesion. 2 0 1
486 24590672 Types of intraocular lenses for cataract surgery in eyes with uveitis. 3 0 1
541 28155990 Dance movement therapy for dementia. 2 0 1
485 27801522 Prophylactic non-steroidal anti-inflammatory drugs for the prevention of macular oedema after cataract surgery. 2 0 1
647 20464755 Balance training (proprioceptive training) for patients with rheumatoid arthritis. 2 0 1
648 25862243 Balneotherapy (or spa therapy) for rheumatoid arthritis. 2 0 1
650 10796385 Balneotherapy for rheumatoid arthritis and osteoarthritis. 3 0 1
651 14583923 Balneotherapy for rheumatoid arthritis. 2 0 1
652 27271314 Biologic interventions for fatigue in rheumatoid arthritis. 2 0 1
653 27855242 Biologic or tofacitinib monotherapy for rheumatoid arthritis in people with traditional disease-modifying anti-rheumatic drug (DMARD) failure: a Cochrane Systematic Review and network meta-analysis (NMA). 3 0 1
655 28481462 Biologics or tofacitinib for people with rheumatoid arthritis naive to methotrexate: a systematic review and network meta-analysis. 2 0 1
656 28282491 Biologics or tofacitinib for people with rheumatoid arthritis unsuccessfully treated with biologics: a systematic review and network meta-analysis. 2 0 1
657 27175934 Biologics or tofacitinib for rheumatoid arthritis in incomplete responders to methotrexate or other traditional disease-modifying anti-rheumatic drugs: a systematic review and network meta-analysis. 3 0 1
658 20824874 Botulinum toxin for shoulder pain. 3 0 1
661 23076921 Cemented, cementless or hybrid fixation options in total knee arthroplasty for osteoarthritis and other non-traumatic diseases. 3 0 1
662 28884785 Certolizumab pegol (CDP870) for rheumatoid arthritis in adults. 2 0 1
663 14583965 Chloroquine as a steroid sparing agent for asthma. 5 0 1
664 17054279 Colchicine for acute gout. 2 0 1
575 24563468 Metal protein attenuating compounds for the treatment of Alzheimer's dementia. 2 0 1
699 26513223 High-intensity versus low-intensity physical activity or exercise in people with hip or knee osteoarthritis. 4 0 1
574 30891742 Memantine for dementia. 5 0 1
570 19821317 Light therapy for managing cognitive, sleep, functional, behavioural, or psychiatric disturbances in dementia. 1 0 1
483 26186173 Non-steroidal anti-inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non-radiographic axial spondyloarthritis). 5 0 1
456 17943774 Oral versus intra-vaginal imidazole and triazole anti-fungal treatment of uncomplicated vulvovaginal candidiasis (thrush). 2 0 1
457 10796567 Prevention of oral mucositis or oral candidiasis for patients with cancer receiving chemotherapy (excluding head and neck cancer). 4 0 1
459 28417451 Prophylactic anti-staphylococcal antibiotics for cystic fibrosis. 2 0 1
460 12917916 Prophylactic antibiotics for cystic fibrosis. 2 0 1
547 12519608 Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia. 2 0 1
548 25177838 Efficacy and experiences of telephone counselling for informal carers of people with dementia. 1 0 1
549 11687175 Efficacy of nicergoline in dementia and other age associated forms of cognitive impairment. 2 0 1
550 26074478 Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery. 2 0 1
552 30021248 Environmental and behavioural modifications for improving food and fluid intake in people with dementia. 2 0 1
554 14584018 Folic acid with or without vitamin B12 for cognition and dementia. 5 0 1
555 22336826 Functional analysis-based interventions for challenging behaviour in dementia. 1 0 1
544 25632881 Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies. 2 0 1
558 12076456 Haloperidol for agitation in dementia. 1 0 1
560 19160224 Hormone replacement therapy to maintain cognitive function in women with dementia. 2 0 1
561 19370686 Huperzine A for vascular dementia. 2 0 1
562 11405961 Hydergine for dementia. 1 0 1
563 22786527 Hyperbaric oxygen therapy for vascular dementia. 2 0 1
564 24990271 Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a general practice (primary care) setting. 1 0 1
565 25754745 Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. 1 0 1
566 24719028 Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within community dwelling populations. 1 0 1
568 12917896 Lecithin for dementia and cognitive impairment. 3 0 1
569 24574061 Light therapy for improving cognition, activities of daily living, sleep, challenging behaviour, and psychiatric disturbances in dementia. 1 0 1
559 12535487 Homeopathy for dementia. 1 0 1
546 28617932 Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia. 3 0 1
545 23990315 Driving assessment for maintaining mobility and safety in drivers with dementia. 1 0 1
511 29164600 18F PET with florbetaben for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). 5 0 1
470 29667726 Interventions for infantile haemangiomas of the skin. 1 0 1
461 11687074 Topical treatment for vaginal candidiasis (thrush) in pregnancy. 1 0 1
462 10796183 Topical treatment for vaginal candidiasis in pregnancy. 1 0 1
464 10796480 Combined inhaled anticholinergic agents and beta-2-agonists for initial treatment of acute asthma in children. 1 0 1
465 17636617 Corticosteroids for preventing relapse following acute exacerbations of asthma. 2 0 1
466 24037768 Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma. 2 0 1
479 19821414 Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema. 1 0 1
467 12917881 Holding chambers versus nebulisers for beta-agonist treatment of acute asthma. 1 0 1
469 29424930 Inhaled mannitol for cystic fibrosis. 2 0 1
471 23152273 Ketamine for management of acute exacerbations of asthma in children. 2 0 1
509 15106220 Penicillins for the prophylaxis of bacterial endocarditis in dentistry. 1 0 1
472 10796650 Magnesium sulfate for treating exacerbations of acute asthma in the emergency department. 1 0 1
473 22972146 Medical treatment for small abdominal aortic aneurysms. 4 0 1
474 12917931 Neuraminidase inhibitors for preventing and treating influenza in children. 1 0 1
475 25806562 Prophylactic milrinone for the prevention of low cardiac output syndrome and mortality in children undergoing surgery for congenital heart disease. 15 0 1
476 28727896 ProSeal versus Classic laryngeal mask airway (LMA) for positive pressure ventilation in adults undergoing elective surgery. 2 0 1
477 24014230 Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese patients. 3 0 1
468 16625566 Inhaled hyperosmolar agents for bronchiectasis. 2 0 1
508 23904048 Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications. 2 0 1
363 28075489 Cough augmentation techniques for extubation or weaning critically ill patients from mechanical ventilation. 2 0 1
1647 12804477 Heparin for pregnant women with acquired or inherited thrombophilias. 5 0 1
365 10796748 Deoxyribonuclease for cystic fibrosis. 1 0 1
1612 12076473 Physical therapies for prevention of urinary and faecal incontinence in adults. 1 0 1
1614 16034933 Prevention and treatment of urinary incontinence after stroke in adults. 1 0 1
1615 10796861 Prompted voiding for the management of urinary incontinence in adults. 1 0 1
1616 28176333 Selective versus routine use of episiotomy for vaginal birth. 2 0 1
1617 16034945 Serotonin and noradrenaline reuptake inhibitors (SNRI) for stress urinary incontinence in adults. 1 0 1
1619 28746980 Single-incision sling operations for urinary incontinence in women. 1 0 1
1620 11686996 Suburethral sling operations for urinary incontinence in women. 1 0 1
1622 27901278 Surgery for women with anterior compartment prolapse. 1 0 1
1623 27696355 Surgery for women with apical vaginal prolapse. 1 0 1
1624 30121956 Surgery for women with pelvic organ prolapse with or without stress urinary incontinence. 3 0 1
1625 23633316 Surgical management of pelvic organ prolapse in women. 2 0 1
1626 14973993 Timed voiding for the management of urinary incontinence in adults. 1 0 1
1627 28743177 Traditional suburethral sling operations for urinary incontinence in women. 1 0 1
1628 25785555 Transurethral radiofrequency collagen denaturation for the treatment of women with urinary incontinence. 1 0 1
1659 27197069 Fasting for haemostasis in children with gastrointestinal bleeding. 7 0 1
1376 16625620 Total versus subtotal hysterectomy for benign gynaecological conditions. 2 0 1
1660 19370633 Vaccines for preventing anthrax. 1 0 1
1662 27996088 Oral zinc for treating diarrhoea in children. 1 0 1
1695 28832903 Drug-eluting stents versus bare-metal stents for acute coronary syndrome. 14 0 1
1696 21678378 Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome. 14 0 1
1613 26196961 Planned caesarean section for term breech delivery. 2 0 1
1611 17636740 Periurethral injection therapy for urinary incontinence in women. 1 0 1
1644 23884904 Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction. 5 0 1
1610 30288727 Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women. 1 0 1
1633 22336788 Urinary diversion and bladder reconstruction/replacement using intestinal segments for intractable incontinence or following cystectomy. 8 0 1
1646 14973983 Corticosteroids for HELLP syndrome in pregnancy. 5 0 1
1648 24249524 Interventions for hyperthyroidism pre-pregnancy and during pregnancy. 5 0 1
1649 20824882 Interventions for preventing and treating hyperthyroidism in pregnancy. 5 0 1
1650 25390767 Interventions for preventing or reducing domestic violence against pregnant women. 1 0 1
1651 12535464 Interventions for treating placental abruption. 1 0 1
1652 21069663 Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. 3 0 1
1653 28407219 Multiple-micronutrient supplementation for women during pregnancy. 3 0 1
1654 26599471 Planned early delivery versus expectant management of the term suspected compromised baby for improving outcomes. 7 0 1
1655 26415762 Vitamin C supplementation in pregnancy. 4 0 1
1656 26343254 Vitamin E supplementation in pregnancy. 4 0 1
3184 30246875 Antibiotics for treating scrub typhus. 3 0 1
1631 18254050 Treatment of urinary incontinence after stroke in adults. 2 0 1
1630 23450602 Treatment of recurrent stress urinary incontinence after failed minimally invasive synthetic suburethral tape surgery in women. 1 0 1
1629 26858090 Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse. 1 0 1
1606 28741303 Open retropubic colposuspension for urinary incontinence in women. 2 0 1
1607 26526663 Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary incontinence in women. 1 0 1
1608 29271473 Pelvic floor muscle training for prevention and treatment of urinary and faecal incontinence in antenatal and postnatal women. 1 0 1
1609 11279716 Pelvic floor muscle training for urinary incontinence in women. 1 0 1
1697 24482073 Endoscopic release for carpal tunnel syndrome. 15 0 1
1698 26845288 Enzyme replacement therapy with idursulfase for mucopolysaccharidosis type II (Hunter syndrome). 16 0 1
1699 22259003 Ergonomic positioning or equipment for treating carpal tunnel syndrome. 13 0 1
1700 22696387 Exercise and mobilisation interventions for carpal tunnel syndrome. 13 0 1
1668 25361381 Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome. 15 0 1
1669 25749695 Antibiotics for treating acute chest syndrome in people with sickle cell disease. 14 0 1
1670 23728677 Antidepressants for polycystic ovary syndrome. 14 0 1
1671 28968483 Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome. 17 0 1
1673 24563180 Aromatase inhibitors for subfertile women with polycystic ovary syndrome. 14 0 1
1675 29110304 Beta-blockers for preventing aortic dissection in Marfan syndrome. 15 0 1
1676 25521793 Biologics, colchicine, corticosteroids, immunosuppressants and interferon-alpha for Neuro-Behçet's Syndrome. 14 0 1
1677 29304272 Botulinum toxin for motor and phonic tics in Tourette's syndrome. 14 0 1
1678 22161392 Botulinum toxin injections for adults with overactive bladder syndrome. 13 0 1
1679 23728685 Breathing exercises for dysfunctional breathing/hyperventilation syndrome in adults. 12 0 1
1680 24347088 Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children. 13 0 1
1682 22336848 Cabergoline for preventing ovarian hyperstimulation syndrome. 13 0 1
1683 23999944 Cervico-thoracic or lumbar sympathectomy for neuropathic pain and complex regional pain syndrome. 13 0 1
1684 27731904 Chinese herbal medicine for subfertile women with polycystic ovarian syndrome. 14 0 1
1685 23740567 Chinese herbal medicine Huangqi type formulations for nephrotic syndrome. 15 0 1
1686 28535578 Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome. 14 0 1
1687 26690260 Comparison of animal-derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants. 13 0 1
1661 20687081 Antibiotic therapy for Shigella dysentery. 1 0 1
1845 29800486 Education of healthcare professionals for preventing pressure ulcers. 1 0 1
1667 28806480 Aerosolized prostacyclins for acute respiratory distress syndrome (ARDS). 14 0 1
1666 20687093 Aerosolized prostacyclin for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). 13 0 1
1664 30521680 Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome. 14 0 1
1712 26202854 Hyperbaric oxygen therapy for acute coronary syndrome. 13 0 1
1703 28295159 First and second trimester serum tests with and without first trimester ultrasound tests for Down's syndrome screening. 13 0 1
1704 26617074 First trimester serum tests for Down's syndrome screening. 12 0 1
1705 28295158 First trimester ultrasound tests alone or in combination with first trimester serum tests for Down's syndrome screening. 13 0 1
1693 27901279 Dopamine agonists for preventing ovarian hyperstimulation syndrome. 14 0 1
1707 26350625 Gonadotrophins for ovulation induction in women with polycystic ovarian syndrome. 14 0 1
1709 23740697 High versus low positive end-expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute lung injury and acute respiratory distress syndrome. 13 0 1
1710 27043185 High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome. 14 0 1
1711 23450549 High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome. 13 0 1
1713 30677127 Immunonutrition for acute respiratory distress syndrome (ARDS) in adults. 14 0 1
1663 30105749 Acupuncture and acupressure for premenstrual syndrome. 14 0 1
1714 25318831 Immunosuppressive treatment for idiopathic membranous nephropathy in adults with nephrotic syndrome. 15 0 1
1715 30480769 In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction. 14 0 1
1716 28378502 Infant pacifiers for reduction in risk of sudden infant death syndrome. 14 0 1
1717 27673392 Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease. 16 0 1
1708 30648738 Gonadotrophins for ovulation induction in women with polycystic ovary syndrome. 15 0 1
1692 22161366 Diuretics for respiratory distress syndrome in preterm infants. 14 0 1
1691 21249645 Digoxin for preventing or treating neonatal respiratory distress syndrome. 15 0 1
1690 25348770 Deferasirox for managing iron overload in people with myelodysplastic syndrome. 14 0 1
1645 28949421 Calcium supplementation commencing before or early in pregnancy, or food fortification with calcium, for preventing hypertensive disorders of pregnancy. 4 0 1
1643 16235350 Trypanocidal drugs for late stage, symptomatic Chagas disease (Trypanosoma cruzi infection). 4 0 1
1775 25178118 Statins for acute coronary syndrome. 15 0 1
1740 22696324 Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. 14 0 1
1743 24327265 Lipid-lowering agents for nephrotic syndrome. 16 0 1
1745 23450544 Lung protective ventilation strategy for the acute respiratory distress syndrome. 13 0 1
1746 23543530 Megestrol acetate for treatment of anorexia-cachexia syndrome. 12 0 1
1747 28118681 Metformin during ovulation induction with gonadotrophins followed by timed intercourse or intrauterine insemination for subfertility associated with polycystic ovary syndrome. 16 0 1
1748 22513976 Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome. 13 0 1
1749 23076945 Nebulised surfactant in preterm infants with or at risk of respiratory distress syndrome. 14 0 1
1736 22592724 Iron for restless legs syndrome. 14 0 1
1786 28272834 Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer. 15 0 1
1787 26662198 Urine tests for Down's syndrome screening. 12 0 1
1788 27577848 Volume expanders for the prevention of ovarian hyperstimulation syndrome. 15 0 1
1820 23784872 High-dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin lymphoma. 1 0 1
1821 18254036 High-dose chemotherapy with autologous stem cell transplantation in the first line treatment of aggressive non-Hodgkin lymphoma (NHL) in adults. 3 0 1
1823 19588373 Interventions for previously untreated patients with AIDS-associated non-Hodgkin's lymphoma. 3 0 1
1824 17443616 Interventions for treating AIDS-associated Hodgkin s lymphoma in treatment-naive adults. 2 0 1
1825 26840029 Meditation for adults with haematological malignancies. 1 0 1
1826 30001476 Nivolumab for adults with Hodgkin's lymphoma (a rapid review using the software RobotReviewer). 6 0 1
1827 28901021 Optimisation of chemotherapy and radiotherapy for untreated Hodgkin lymphoma patients with respect to second malignant neoplasms, overall and progression-free survival: individual participant data analysis. 3 0 1
1828 25572491 Positron emission tomography-adapted therapy for first-line treatment in individuals with Hodgkin lymphoma. 2 0 1
1829 23152274 Role of chemotherapy additional to high-dose methotrexate for primary central nervous system lymphoma (PCNSL). 2 0 1
1742 30921477 Lifestyle changes in women with polycystic ovary syndrome. 15 0 1
1739 25985235 L-acetylcarnitine for treating fragile X syndrome. 15 0 1
1641 30326162 Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X-linked dilated cardiomyopathy. 5 0 1
1735 21735432 Intratympanic steroids for Ménière's disease or syndrome. 13 0 1
1777 28953318 Terlipressin versus other vasoactive drugs for hepatorenal syndrome. 14 0 1
1778 29943803 Terlipressin versus placebo or no intervention for people with cirrhosis and hepatorenal syndrome. 15 0 1
1779 23543580 Therapeutic ultrasound for carpal tunnel syndrome. 13 0 1
1780 23818100 Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol. 14 0 1
1783 22696361 Treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome. 14 0 1
1771 22696388 Second trimester serum tests for Down's Syndrome screening. 12 0 1
1784 25984923 Treatment for postpolio syndrome. 14 0 1
1752 22336820 Oral contraceptives containing drospirenone for premenstrual syndrome. 13 0 1
1750 29231243 Neuromuscular electrical stimulation (NMES) for patellofemoral pain syndrome. 14 0 1
1722 24385385 Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome. 14 0 1
1724 29183107 Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. 16 0 1
1725 27819409 Interventions for chronic kidney disease-associated restless legs syndrome. 18 0 1
1726 27726125 Interventions for idiopathic steroid-resistant nephrotic syndrome in children. 15 0 1
1727 22513919 Interventions for preventing infection in nephrotic syndrome. 13 0 1
1728 25781421 Interventions for the treatment of Frey's syndrome. 13 0 1
1729 24482008 Interventions for the treatment of twin-twin transfusion syndrome. 12 0 1
1732 21328249 Intra-venous fluids for the prevention of severe ovarian hyperstimulation syndrome. 13 0 1
1733 21563168 Intratracheal Clara cell secretory protein (CCSP) administration in preterm infants with or at risk of respiratory distress syndrome. 14 0 1
1751 24166716 Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children. 13 0 1
1819 18843642 Granulopoiesis-stimulating factors to prevent adverse effects in the treatment of malignant lymphoma. 2 0 1
1830 24931518 The role of additional radiotherapy for primary central nervous system lymphoma. 1 0 1
1832 17054245 Therapeutic interventions for Burkitt's lymphoma in children. 1 0 1
1834 29734473 Treatment for hepatitis C virus-associated mixed cryoglobulinaemia. 8 0 1
1806 29178265 Surgical interventions for vertical strabismus in superior oblique palsy. 2 0 1
1807 29105728 Tests for detecting strabismus in children aged 1 to 6 years in the community. 1 0 1
1808 26484982 Additional plerixafor to granulocyte colony-stimulating factors for haematopoietic stem cell mobilisation for autologous transplantation in people with malignant lymphoma or multiple myeloma. 3 0 1
1809 30827035 Adjuvant gonadotropin-releasing hormone analogues for the prevention of chemotherapy-induced premature ovarian failure in premenopausal women. 4 0 1
1810 30702150 Aerobic physical exercise for adult patients with haematological malignancies. 3 0 1
1811 23986525 Allogeneic stem cell transplantation versus conventional therapy for advanced primary cutaneous T-cell lymphoma. 3 0 1
1812 27548292 Alternatives, and adjuncts, to prophylactic platelet transfusion for people with haematological malignancies undergoing intensive chemotherapy or stem cell transplantation. 2 0 1
1813 22258955 Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy. 1 0 1
1814 26784573 Antibody therapies for lymphoma in children. 1 0 1
1815 28447341 Chemotherapy alone versus chemotherapy plus radiotherapy for adults with early stage Hodgkin lymphoma. 1 0 1
1721 25927089 Inositol in preterm infants at risk for or having respiratory distress syndrome. 16 0 1
1720 30570133 Inositol for subfertile women with polycystic ovary syndrome. 14 0 1
1719 22419275 Inositol for respiratory distress syndrome in preterm infants. 16 0 1
1718 27347773 Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults. 15 0 1
1634 12137680 Urodynamic investigations for management of urinary incontinence in adults. 1 0 1
1635 24166676 Urodynamic studies for management of urinary incontinence in children and adults. 1 0 1
1637 30816997 Yoga for treating urinary incontinence in women. 2 0 1
1638 29081716 Yoga for treatment of urinary incontinence in women. 1 0 1
1640 24683002 Anticoagulation versus placebo for heart failure in sinus rhythm. 5 0 1
1803 12804487 Interventions for intermittent distance exotropia. 2 0 1
1802 23897277 Interventions for infantile esotropia. 2 0 1
1801 29505103 Interventions for eye movement disorders due to acquired brain injury. 4 0 1
1818 12519588 Granulopoiesis-stimulating factors in the prevention for adverse effects in the therapeutic treatment of malignant lymphoma. 2 0 1
1835 25188452 Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer. 6 0 1
1836 14974022 Tumor necrosis factor-alpha antibody for induction of remission in Crohn's disease. 3 0 1
1837 21412895 Vaccines for prophylaxis of viral infections in patients with hematological malignancies. 5 0 1
1838 24919720 Yoga in addition to standard care for patients with haematological malignancies. 2 0 1
1839 15106214 Dual chamber versus single chamber ventricular pacemakers for sick sinus syndrome and atrioventricular block. 4 0 1
1840 30932166 Constraint-induced movement therapy in children with unilateral cerebral palsy. 2 0 1
1841 22336851 Aloe vera for treating acute and chronic wounds. 1 0 1
1831 21735399 Therapeutic interventions for Burkitt lymphoma in children. 2 0 1
1817 16235316 Chemotherapy, radiotherapy and combined modality for Hodgkin's disease, with emphasis on second cancer risk. 4 0 1
1800 26587695 Interventions for dissociated vertical deviation. 3 0 1
1816 21328291 Chemotherapy alone versus chemotherapy plus radiotherapy for early stage Hodgkin lymphoma. 1 0 1
1790 30835819 Antistreptococcal interventions for guttate and chronic plaque psoriasis. 2 0 1
1791 16437433 Interventions for chronic palmoplantar pustulosis. 2 0 1
1792 10796758 Interventions for guttate psoriasis. 1 0 1
1793 26443004 Interventions for hidradenitis suppurativa. 3 0 1
1794 24151011 Narrow-band ultraviolet B phototherapy versus broad-band ultraviolet B or psoralen-ultraviolet A photochemotherapy for psoriasis. 1 0 1
1795 30958563 Non-antistreptococcal interventions for acute guttate psoriasis or an acute guttate flare of chronic psoriasis. 1 0 1
1798 29527670 Adjustable versus non-adjustable sutures for strabismus. 1 0 1
1375 14974049 Tegaserod for the treatment of irritable bowel syndrome. 3 0 1
1373 16235347 Tacrolimus versus cyclosporin as primary immunosuppression for kidney transplant recipients. 2 0 1
1080 12804433 Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer. 2 0 1
979 28046205 Dietary advice interventions in pregnancy for preventing gestational diabetes mellitus. 5 0 1
981 27602537 Dietary supplementation with myo-inositol in women during pregnancy for treating gestational diabetes. 3 0 1
983 29081069 Different methods and settings for glucose monitoring for gestational diabetes during pregnancy. 3 0 1
973 26678256 Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. 2 0 1
986 11406020 Elective delivery in diabetic pregnant women. 1 0 1
961 27362975 Short-acting insulin analogues versus regular human insulin for adults with type 1 diabetes mellitus. 2 0 1
959 19160294 Metformin added to insulin therapy for type 1 diabetes mellitus in adolescents. 2 0 1
939 27610712 Non-steroid anti-inflammatory drugs for biliary colic. 5 0 1
940 23939652 Percutaneous cholecystostomy for high-risk surgical patients with acute calculous cholecystitis. 1 0 1
941 17443609 Routine abdominal drainage for uncomplicated open cholecystectomy. 2 0 1
942 24000011 Routine abdominal drainage versus no abdominal drainage for uncomplicated laparoscopic cholecystectomy. 1 0 1
943 25177839 Computed tomography angiography or magnetic resonance angiography for detection of intracranial vascular malformations in patients with intracerebral haemorrhage. 1 0 1
944 26130264 Surgery for epilepsy. 5 0 1
945 27409709 Rapamycin and rapalogs for tuberous sclerosis complex. 4 0 1
946 23832787 Anthracycline-containing regimens for treatment of follicular lymphoma in adults. 2 0 1
947 22258971 High-dose therapy with autologous stem cell transplantation versus chemotherapy or immuno-chemotherapy for follicular lymphoma in adults. 2 0 1
960 17443539 Routine hospital admission versus out-patient or home care in children at diagnosis of type 1 diabetes mellitus. 2 0 1
948 20091564 Interferon-alpha for maintenance of follicular lymphoma. 3 0 1
950 20091555 Glucocorticosteroids for primary sclerosing cholangitis. 7 0 1
951 28417463 Pharmacological interventions for primary sclerosing cholangitis: an attempted network meta-analysis. 7 0 1
980 10796112 Dietary regulation for 'gestational diabetes'. 1 0 1
978 18425961 Dietary advice in pregnancy for preventing gestational diabetes mellitus. 3 0 1
1081 17443560 Chinese medicinal herbs to treat the side-effects of chemotherapy in breast cancer patients. 5 0 1
977 26068707 Diet or exercise, or both, for preventing excessive weight gain in pregnancy. 3 0 1
1124 23633376 Mammography in combination with breast ultrasonography versus mammography for breast cancer screening in women at average risk. 1 0 1
1053 30616299 Routine preoperative medical testing for cataract surgery. 1 0 1
1149 17943751 Phytoestrogens for vasomotor menopausal symptoms. 1 0 1
1052 20464726 Radiotherapy for neovascular age-related macular degeneration. 3 0 1
1047 26133124 Peribulbar versus retrobulbar anaesthesia for cataract surgery. 1 0 1
963 27128768 Transition of care for adolescents from paediatric services to adult health services. 2 0 1
964 18425919 Antacids for preventing oesophagogastric variceal bleeding and rebleeding in cirrhotic patients. 1 0 1
965 30372514 Carvedilol versus traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices. 1 0 1
966 23450530 Drugs for treating Schistosoma mansoni infection. 3 0 1
967 25966446 Endoscopic injection of cyanoacrylate glue versus other endoscopic procedures for acute bleeding gastric varices in people with portal hypertension. 3 0 1
968 16856046 Endothelin receptor antagonists for pulmonary arterial hypertension. 6 0 1
969 28850173 Interventions for preventing and managing advanced liver disease in cystic fibrosis. 6 0 1
970 28351116 Management of people with early- or very early-stage hepatocellular carcinoma: an attempted network meta-analysis. 4 0 1
971 28281295 Management of people with intermediate-stage hepatocellular carcinoma: an attempted network meta-analysis. 4 0 1
962 25220222 Steroid avoidance or withdrawal for pancreas and pancreas with kidney transplant recipients. 4 0 1
972 30378107 Surgical portosystemic shunts versus transjugular intrahepatic portosystemic shunt for variceal haemorrhage in people with cirrhosis. 3 0 1
974 29129039 Combined diet and exercise interventions for preventing gestational diabetes mellitus. 4 0 1
975 27272351 Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes. 3 0 1
976 25864059 Diet and exercise interventions for preventing gestational diabetes mellitus. 4 0 1
952 22258980 Continuous glucose monitoring systems for type 1 diabetes mellitus. 2 0 1
953 20091571 Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus. 3 0 1
954 22696371 Enhanced glucose control for preventing and treating diabetic neuropathy. 4 0 1
955 23543528 Hormonal versus non-hormonal contraceptives in women with diabetes mellitus type 1 and 2. 2 0 1
1041 28245346 N-acetylcarnosine (NAC) drops for age-related cataract. 1 0 1
1042 28570745 Nd:YAG laser vitreolysis versus pars plana vitrectomy for vitreous floaters. 5 0 1
1043 24532137 Non-penetrating filtration surgery versus trabeculectomy for open-angle glaucoma. 2 0 1
1044 22336801 Non-steroidal anti-inflammatory agents for treating cystoid macular oedema following cataract surgery. 1 0 1
1046 30848830 Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments. 4 0 1
1036 24114262 Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus phacoemulsification with posterior chamber intraocular lens for age-related cataract. 1 0 1
1023 28125765 Corticosteroids as adjuvant therapy for ocular toxoplasmosis. 3 0 1
1022 29460275 Community screening for visual impairment in older people. 2 0 1
1021 26171900 Combined surgery versus cataract surgery alone for eyes with cataract and glaucoma. 2 0 1
991 29103210 Insulin for the treatment of women with gestational diabetes. 3 0 1
993 22258997 Interventions for pregnant women with hyperglycaemia not meeting gestational diabetes and type 2 diabetes diagnostic criteria. 1 0 1
995 30039871 Metformin for women who are overweight or obese during pregnancy for improving maternal and infant outcomes. 6 0 1
996 29045765 Oral anti-diabetic agents for women with established diabetes/impaired glucose tolerance or previous gestational diabetes planning pregnancy, or pregnant women with pre-existing diabetes. 3 0 1
997 20927764 Oral anti-diabetic agents for women with pre-existing diabetes mellitus/impaired glucose tolerance or previous gestational diabetes mellitus. 3 0 1
999 29423911 Planned birth at or near term for improving health outcomes for pregnant women with pre-existing diabetes and their infants. 1 0 1
1000 15846641 Prevention of recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulant. 2 0 1
1001 24574258 Probiotics for preventing gestational diabetes. 4 0 1
1002 24638998 Reminder systems for women with previous gestational diabetes mellitus to increase uptake of testing for type 2 diabetes or impaired glucose tolerance. 3 0 1
1004 26387772 Screening and subsequent management for thyroid dysfunction pre-pregnancy and during pregnancy for improving maternal and infant health. 8 0 1
1040 27943250 Multifocal versus monofocal intraocular lenses after cataract extraction. 1 0 1
1039 26545176 Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. 2 0 1
1038 22972069 Medical versus surgical interventions for open angle glaucoma. 2 0 1
1026 28931202 Different-sized incisions for phacoemulsification in age-related cataract. 3 0 1
956 23744560 Hormone replacement therapy for women with type 1 diabetes mellitus. 2 0 1
957 24526393 Intensive glucose control versus conventional glucose control for type 1 diabetes mellitus. 3 0 1
958 18646147 Intermediate acting versus long acting insulin for type 1 diabetes mellitus. 2 0 1
949 19370640 Rituximab as maintenance therapy for patients with follicular lymphoma. 2 0 1
987 16856038 Exercise for diabetic pregnant women. 1 0 1
988 22786521 Exercise for pregnant women for preventing gestational diabetes mellitus. 5 0 1
990 29264871 Exercise for pregnant women with pre-existing diabetes for improving maternal and fetal outcomes. 1 0 1
1025 26625212 Device-modified trabeculectomy for glaucoma. 2 0 1
1027 14583947 Interventions for normal tension glaucoma. 3 0 1
1037 30640411 Medical interventions for traumatic hyphema. 3 0 1
1028 22972103 Interventions for preventing falls in older people living in the community. 2 0 1
1029 20166069 Interventions for preventing posterior capsule opacification. 1 0 1
1030 16856079 Interventions for stimulus deprivation amblyopia. 3 0 1
1031 29119547 Interventions to improve access to cataract surgical services and their impact on equity in low- and middle-income countries. 1 0 1
1032 16235305 Intra-operative mitomycin C for glaucoma surgery. 3 0 1
1034 27387849 Laser-assisted cataract surgery versus standard ultrasound phacoemulsification cataract surgery. 1 0 1
1024 26524611 Day care versus in-patient surgery for age-related cataract. 2 0 1
1035 25405603 Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract. 2 0 1
1123 28093732 Long-term hormone therapy for perimenopausal and postmenopausal women. 7 0 1
1122 22786488 Long term hormone therapy for perimenopausal and postmenopausal women. 5 0 1
1121 26718728 Localization techniques for guided surgical excision of non-palpable breast lesions. 1 0 1
1066 21069675 Addition of drug/s to a chemotherapy regimen for metastatic breast cancer. 2 0 1
1054 26308931 Sub-Tenon's anaesthesia versus topical anaesthesia for cataract surgery. 1 0 1
1055 19370663 Submacular surgery for choroidal neovascularisation secondary to age-related macular degeneration. 3 0 1
1057 24357418 Surgery for post-vitrectomy cataract. 3 0 1
1058 29364503 Surgery for postvitrectomy cataract. 2 0 1
1059 17943833 Surgical implantation of steroids with antiangiogenic characteristics for treating neovascular age-related macular degeneration. 1 0 1
1060 17054134 Surgical interventions for age-related cataract. 1 0 1
1061 16855998 Surgical interventions for bilateral congenital cataract. 4 0 1
1063 17636793 Topical anaesthesia alone versus topical anaesthesia with intracameral lidocaine for phacoemulsification. 1 0 1
1064 25965055 Vitrectomy for idiopathic macular hole. 3 0 1
1077 29542106 Breast surgery for metastatic breast cancer. 2 0 1
1065 23897589 Acupuncture for menopausal hot flushes. 1 0 1
1067 18646135 Antenatal breast examination for promoting breastfeeding. 1 0 1
1068 15106193 Antibiotics / anti-inflammatories for reducing acute inflammatory episodes in lymphoedema of the limbs. 2 0 1
1069 15495049 Antitumour antibiotic containing regimens for metastatic breast cancer. 1 0 1
1070 19821307 Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women. 1 0 1
1071 27960229 Automated telephone communication systems for preventive healthcare and management of long-term conditions. 7 0 1
1072 28052186 Axillary treatment for operable primary breast cancer. 3 0 1
1073 15106192 Benzo-pyrones for reducing and controlling lymphoedema of the limbs. 1 0 1
1074 27479272 Bioidentical hormones for women with vasomotor symptoms. 3 0 1
1076 16034900 Bisphosphonates for breast cancer. 2 0 1
1078 22336791 Cancer genetic risk assessment for individuals at risk of familial breast cancer. 1 0 1
1100 16034886 High dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with early poor prognosis breast cancer. 1 0 1
1089 27650122 Exercise for women receiving adjuvant therapy for breast cancer. 2 0 1
1082 24347031 Combination versus sequential single agent chemotherapy for metastatic breast cancer. 2 0 1
1083 25677413 Conservative interventions for preventing clinically detectable upper-limb lymphoedema in patients who are at risk of developing lymphoedema after breast cancer therapy. 2 0 1
1084 25565627 Dance/movement therapy for improving psychological and physical outcomes in cancer patients. 3 0 1
1085 26613337 Decision aids for people considering taking part in clinical trials. 5 0 1
1086 28402085 Decision aids for people facing health treatment or screening decisions. 2 0 1
1087 27182693 Different types of implants for reconstructive breast surgery. 1 0 1
1088 23152233 Exercise for the management of cancer-related fatigue in adults. 2 0 1
1079 21678342 Cardioprotective interventions for cancer patients receiving anthracyclines. 2 0 1
1091 20556760 Exercise interventions for upper-limb dysfunction due to breast cancer treatment. 2 0 1
1090 30536366 Exercise interventions for people undergoing multimodal cancer treatment that includes surgery. 2 0 1
1092 22895961 Exercise interventions on health-related quality of life for cancer survivors. 2 0 1
1093 22895974 Exercise interventions on health-related quality of life for people with cancer during active treatment. 1 0 1
1094 23904353 Exercise training undertaken by people within 12 months of lung resection for non-small cell lung cancer. 4 0 1
1095 23728694 Fibrin glue instillation under skin flaps to prevent seroma-related morbidity following breast and axillary surgery. 1 0 1
1096 27230946 Follow-up strategies for women treated for early breast cancer. 2 0 1
1097 27425588 Fraction size in radiation therapy for breast conservation in early breast cancer. 2 0 1
1098 21069678 Fraction size in radiation treatment for breast conservation in early breast cancer. 1 0 1
1099 28043088 Fulvestrant for hormone-sensitive metastatic breast cancer. 2 0 1
1075 29082518 Bisphosphonates and other bone agents for breast cancer. 3 0 1
1101 16034887 High dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with metastatic breast cancer. 1 0 1
1120 29926477 Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children. 1 0 1
1102 27241086 High dose, high risk? What updated evidence tells us about chemotherapy dosing in early breast cancer. 2 0 1
1127 17636820 Methods of communicating a primary diagnosis of breast cancer to patients. 1 0 1
1126 27258432 Massage with or without aromatherapy for symptom relief in people with cancer. 2 0 1
1125 25994425 Manual lymphatic drainage for lymphedema following breast cancer treatment. 3 0 1
1104 28836379 Home-based multidimensional survivorship programmes for breast cancer survivors. 3 0 1
1105 19370613 Homeopathic medicines for adverse effects of cancer treatments. 3 0 1
1106 29763969 Hormone replacement therapy for women previously treated for endometrial cancer. 5 0 1
1107 21735435 Immediate versus delayed reconstruction following surgery for breast cancer. 1 0 1
1108 30229557 Interventions for promoting habitual exercise in people living with and beyond cancer. 3 0 1
1109 28185268 Interventions for raising breast cancer awareness in women. 2 0 1
1110 18254010 Interventions for relieving the pain and discomfort of screening mammography. 1 0 1
1111 26830050 Interventions for sexual dysfunction following treatments for cancer in women. 3 0 1
1112 26919630 Interventions for treating bisphosphonate-related osteonecrosis of the jaw (BRONJ). 4 0 1
1113 26405010 Interventions to enhance return-to-work for cancer patients. 3 0 1
1114 29406579 Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews. 1 0 1
1115 15674924 Lay health workers in primary and community health care. 2 0 1
1116 26649916 Levonorgestrel intrauterine system for endometrial protection in women with breast cancer on adjuvant tamoxifen. 5 0 1
1117 23737032 Levonorgestrel-releasing intrauterine system for atypical endometrial hyperplasia. 4 0 1
1118 19821328 LHRH agonists for adjuvant therapy of early breast cancer in premenopausal women. 1 0 1
1119 23076930 Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery. 1 0 1
1139 12804406 Oestrogens for urinary incontinence in women. 2 0 1
1148 24323914 Phytoestrogens for menopausal vasomotor symptoms. 1 0 1
1147 15495042 Physical therapies for reducing and controlling lymphoedema of the limbs. 1 0 1
1136 20824841 Non-hormonal interventions for hot flushes in women with a history of breast cancer. 1 0 1
1103 27200512 High-dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with early poor prognosis breast cancer. 2 0 1
1129 18425885 Mistletoe therapy in oncology. 3 0 1
1130 27513824 Mobile clinics for women's and children's health. 1 0 1
1131 25140980 Motivational interviewing for alcohol misuse in young adults. 2 0 1
1132 11869577 Multi-agent chemotherapy for early breast cancer. 1 0 1
1133 23235677 Multidisciplinary rehabilitation for follow-up of women treated for breast cancer. 1 0 1
1134 27898991 Nipple- and areola-sparing mastectomy for the treatment of breast cancer. 5 0 1
1135 28257559 Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome. 16 0 1
1137 27529826 Non-pharmacological interventions for cognitive impairment due to systemic cancer treatment. 4 0 1
1146 29376559 Physical activity for women with breast cancer after adjuvant therapy. 2 0 1
1128 30916356 Mindfulness-based stress reduction for women diagnosed with breast cancer. 2 0 1
1138 23076892 Oestrogen therapy for urinary incontinence in post-menopausal women. 2 0 1
1140 28278559 Online support groups for women with breast cancer. 2 0 1
1141 30521671 Oral and intrauterine progestogens for atypical endometrial hyperplasia. 4 0 1
1142 10908474 Ovarian ablation for early breast cancer. 1 0 1
1143 27425375 Partial breast irradiation for early breast cancer. 5 0 1
1144 17054144 Personalised risk communication for informed decision making about taking screening tests. 1 0 1
1145 21069692 Pharmacological treatments for fatigue associated with palliative care. 2 0 1
1776 22972083 Terlipressin for hepatorenal syndrome. 13 0 1
1774 22786532 Splinting for carpal tunnel syndrome. 13 0 1
366 29121400 Dexamethasone as an adjuvant to peripheral nerve block. 3 0 1
329 30536850 Laryngeal mask airway versus endotracheal tube for percutaneous dilatational tracheostomy in critically ill adults. 2 0 1
321 26058966 Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcomes. 2 0 1
331 28056166 Nitric oxide for respiratory failure in infants born at or near term. 4 0 1
333 30701543 Phosphodiesterase 5 inhibitors for pulmonary hypertension. 5 0 1
334 18843713 Physical training for interstitial lung disease. 4 0 1
335 29303230 Planned birth at or near term for improving health outcomes for pregnant women with gestational diabetes and their infants. 7 0 1
337 26410043 Pulse oximeters to self monitor oxygen saturation levels as part of a personalised asthma action plan for people with asthma. 2 0 1
338 18425931 Targeted therapy for advanced renal cell carcinoma. 3 0 1
339 28976555 Techniques for preventing hypotension during spinal anaesthesia for caesarean section. 3 0 1
340 26222247 The use of propofol for procedural sedation in emergency departments. 1 0 1
341 22161374 Tracheal suctioning without disconnection in intubated ventilated neonates. 2 0 1
342 15846679 Universal neonatal hearing screening versus selective screening as part of the management of childhood deafness. 1 0 1
332 24801519 Permissive hypoxaemia versus normoxaemia for mechanically ventilated critically ill patients. 1 0 1
320 12535393 Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease. 2 0 1
319 23440789 Cooling for newborns with hypoxic ischaemic encephalopathy. 4 0 1
318 12076402 Continuous positive airways pressure for obstructive sleep apnoea. 1 0 1
295 30671926 Clinically-indicated replacement versus routine replacement of peripheral venous catheters. 2 0 1
296 16235300 Heparin for prolonging peripheral intravenous catheter use in neonates. 4 0 1
297 11034778 Intravenous prostaglandin for induction of labour. 1 0 1
298 26888026 Lidocaine for reducing propofol-induced pain on induction of anaesthesia in adults. 1 0 1
330 12804388 Nasal continuous positive airways pressure immediately after extubation for preventing morbidity in preterm infants. 2 0 1
328 24979320 Laryngeal mask airway versus endotracheal tube for percutaneous dilatational tracheostomy in critically ill adult patients. 5 0 1
247 26593309 Aminophylline for bradyasystolic cardiac arrest in adults. 1 0 1
327 10796212 Kinesthetic stimulation for treating apnea in preterm infants. 1 0 1
249 26904970 Biphasic versus monophasic waveforms for transthoracic defibrillation in out-of-hospital cardiac arrest. 3 0 1
252 25626888 Cooling for cerebral protection during brain surgery. 7 0 1
253 18425873 Emergency intubation for acutely ill and injured patients. 1 0 1
254 12804491 Epinephrine for the resuscitation of apparently stillborn or extremely bradycardic newborn infants. 1 0 1
255 25608845 Extracorporeal membrane oxygenation for critically ill adults. 2 0 1
257 28657160 Ketamine as an adjuvant to opioids for cancer pain. 2 0 1
258 30125048 Mechanical versus manual chest compressions for cardiac arrest. 2 0 1
259 24464831 Neuraxial blockade for the prevention of postoperative mortality and major morbidity: an overview of Cochrane systematic reviews. 1 0 1
260 27488764 Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non-cardiac surgery. 3 0 1
261 23881653 Partial liquid ventilation for preventing death and morbidity in adults with acute lung injury and acute respiratory distress syndrome. 17 0 1
291 21735416 Sublingual immunotherapy for treating allergic conjunctivitis. 5 0 1
934 17054258 Early versus delayed laparoscopic cholecystectomy for acute cholecystitis. 1 0 1
292 11687081 Tartrazine exclusion for allergic asthma. 2 0 1
294 26982376 Catheter impregnation, coating or bonding for reducing central venous catheter-related infections in adults. 1 0 1
322 19588382 Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer. 2 0 1
323 30380135 Gene therapy for peripheral arterial disease. 3 0 1
324 27404120 Immediate versus deferred delivery of the preterm baby with suspected fetal compromise for improving outcomes. 4 0 1
325 18254121 Inhaled nitric oxide for acute chest syndrome in people with sickle cell disease. 3 0 1
326 28653390 Interventions for preventing high altitude illness: Part 1. Commonly-used classes of drugs. 1 0 1
299 16437480 Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus). 3 0 1
300 30596479 Tranexamic acid for patients with nasal haemorrhage (epistaxis). 1 0 1
302 29478266 Treatment for superficial thrombophlebitis of the leg. 1 0 1
303 28594443 Growth factors for angiogenesis in peripheral arterial disease. 3 0 1
1522 24848893 Laparoscopy for the management of acute lower abdominal pain in women of childbearing age. 1 0 1
1523 21735437 Single incision versus conventional multi-incision appendicectomy for suspected appendicitis. 1 0 1
1524 26171909 Effects of opioid, hypnotic and sedating medications on sleep-disordered breathing in adults with obstructive sleep apnoea. 2 0 1
1526 25113164 Pharmacological interventions for sleepiness and sleep disturbances caused by shift work. 2 0 1
1513 28358980 Pharmacological interventions for non-alcohol related fatty liver disease (NAFLD): an attempted network meta-analysis. 8 0 1
1529 24833028 Adjuvant treatment of anaplastic oligodendrogliomas and oligoastrocytomas. 2 0 1
1533 24526345 Endothelial keratoplasty versus penetrating keratoplasty for Fuchs endothelial dystrophy. 1 0 1
1535 14583978 Amino acids for amyotrophic lateral sclerosis / motor neuron disease. 3 0 1
1536 17253482 Antioxidant treatment for amyotrophic lateral sclerosis / motor neuron disease. 3 0 1
1538 15266526 Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis/motor neuron disease. 3 0 1
1539 23235621 Creatine for amyotrophic lateral sclerosis/motor neuron disease. 3 0 1
1540 23740607 Drug therapy for pain in amyotrophic lateral sclerosis or motor neuron disease. 3 0 1
1542 28067943 Gamma aminobutyric acid (GABA) modulators for amyotrophic lateral sclerosis/motor neuron disease. 4 0 1
1543 22258985 Interventions for fatigue and weight loss in adults with advanced progressive illness. 9 0 1
1544 22972143 Magnesium for skeletal muscle cramps. 3 0 1
1530 26118544 Early versus delayed postoperative radiotherapy for treatment of low-grade gliomas. 5 0 1
1546 19821416 Multidisciplinary care for adults with amyotrophic lateral sclerosis or motor neuron disease. 3 0 1
1511 22513975 Sildenafil citrate for erectile dysfunction in patients with multiple sclerosis. 4 0 1
1509 25715323 Remediating buildings damaged by dampness and mould for preventing or reducing respiratory tract symptoms, infections and asthma. 3 0 1
1520 25300594 Intranasal fentanyl for the management of acute pain in children. 2 0 1
1519 28574593 Early versus delayed appendicectomy for appendiceal phlegmon or abscess. 2 0 1
1518 29190038 Closure methods of the appendix stump for complications during laparoscopic appendectomy. 1 0 1
313 10796239 Cardiotocography for antepartum fetal assessment. 1 0 1
304 23076910 Chinese herbs combined with Western medicine for severe acute respiratory syndrome (SARS). 14 0 1
305 17943895 Interventions for the interruption or reduction of the spread of respiratory viruses. 3 0 1
307 15846636 Psychological interventions for non-ulcer dyspepsia. 2 0 1
308 17943915 Psychotherapies for hypochondriasis. 1 0 1
309 12076387 Ambulatory oxygen for chronic obstructive pulmonary disease. 2 0 1
310 24957353 Ambulatory oxygen for people with chronic obstructive pulmonary disease who are not hypoxaemic at rest. 2 0 1
311 20238334 Antibiotics for community-acquired pneumonia in children. 1 0 1
312 27574910 Blood transfusions for treating acute chest syndrome in people with sickle cell disease. 18 0 1
314 28125772 Cardiotocography versus intermittent auscultation of fetal heart on admission to labour ward for assessment of fetal wellbeing. 2 0 1
1515 11686991 Antibiotics versus placebo for prevention of postoperative infection after appendectomy. 2 0 1
315 29341066 Cerebral near-infrared spectroscopy (NIRS) for perioperative monitoring of brain oxygenation in children and adults. 2 0 1
316 25081420 Continuous positive airway pressure (CPAP) during the postoperative period for prevention of postoperative morbidity and mortality following major abdominal surgery. 2 0 1
317 16855960 Continuous positive airways pressure for obstructive sleep apnoea in adults. 1 0 1
293 17253485 Topical nasal steroids for intermittent and persistent allergic rhinitis in children. 2 0 1
935 18843746 Early versus delayed laparoscopic cholecystectomy for biliary colic. 6 0 1
937 23813478 Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic. 5 0 1
938 24558020 Fewer-than-four ports versus four ports for laparoscopic cholecystectomy. 1 0 1
1514 29741752 Abdominal drainage to prevent intra-peritoneal abscess after open appendectomy for complicated appendicitis. 2 0 1
248 26646017 Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death. 3 0 1
246 30653257 Adrenaline and vasopressin for cardiac arrest. 1 0 1
1772 26046493 Selective serotonin reuptake inhibitors for fibromyalgia syndrome. 14 0 1
443 16034902 Inhaled fluticasone at different doses for chronic asthma in adults and children. 3 0 1
445 11687040 Inhaled fluticasone propionate for chronic asthma. 2 0 1
446 15846637 Inhaled fluticasone versus inhaled beclomethasone or inhaled budesonide for chronic asthma in adults and children. 4 0 1
447 15106173 Inhaled fluticasone versus inhaled beclomethasone or inhaled budesonide for chronic asthma. 4 0 1
448 15846649 Inhaled fluticasone versus placebo for chronic asthma in adults and children. 3 0 1
439 17943772 Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children. 4 0 1
424 17253542 Elective surgery for benign liver tumours. 2 0 1
423 22895989 Dietary flavonoid for preventing colorectal neoplasms. 3 0 1
422 28064440 Dietary fibre for the prevention of recurrent colorectal adenomas and carcinomas. 2 0 1
399 22513957 Prophylactic antibiotics to reduce morbidity and mortality in newborn infants with intercostal catheters. 1 0 1
400 10796380 Prophylactic natural surfactant extract for preventing morbidity and mortality in preterm infants. 7 0 1
401 20091513 Prophylactic protein free synthetic surfactant for preventing morbidity and mortality in preterm infants. 9 0 1
402 10796410 Prophylactic synthetic surfactant for preventing morbidity and mortality in preterm infants. 9 0 1
403 10796379 Prophylactic versus selective use of surfactant for preventing morbidity and mortality in preterm infants. 7 0 1
404 11405966 Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants. 7 0 1
405 10796364 Rescue high frequency oscillatory ventilation versus conventional ventilation for pulmonary dysfunction in preterm infants. 1 0 1
407 10796463 Surfactant for meconium aspiration syndrome in full term infants. 3 0 1
408 17636695 Surfactant for meconium aspiration syndrome in full term/near term infants. 3 0 1
409 25504256 Surfactant for meconium aspiration syndrome in term and late preterm infants. 15 0 1
410 23543527 Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants. 4 0 1
444 11869675 Inhaled fluticasone at different doses for chronic asthma. 2 0 1
442 22786484 Inhaled corticosteroids for stable chronic obstructive pulmonary disease. 2 0 1
245 17054240 Adenosine versus intravenous calcium channel antagonists for the treatment of supraventricular tachycardia in adults. 2 0 1
441 18843640 Fluticasone versus placebo for chronic asthma in adults and children. 3 0 1
367 15846747 Early introduction of lipids to parenterally-fed preterm infants. 6 0 1
368 12076469 Early surfactant administration with brief ventilation vs selective surfactant and continued mechanical ventilation for preterm infants with or at risk for RDS. 5 0 1
369 15266470 Early surfactant administration with brief ventilation vs selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome. 5 0 1
360 26141572 Continuous distending pressure for respiratory distress in preterm infants. 4 0 1
396 11279724 Postnatal phenobarbitone for the prevention of intraventricular hemorrhage in preterm infants. 3 0 1
397 23152283 Preoperative physical therapy for elective cardiac surgery patients. 2 0 1
398 11686960 Preoxygenation for tracheal suctioning in intubated, ventilated newborn infants. 1 0 1
426 19821329 Single dose oral rofecoxib for acute postoperative pain in adults. 1 0 1
427 30109701 Transabdominal ultrasound and endoscopic ultrasound for diagnosis of gallbladder polyps. 2 0 1
428 26011829 Water infusion versus air insufflation for colonoscopy. 3 0 1
430 25922860 Antenatal lower genital tract infection screening and treatment programs for preventing preterm delivery. 2 0 1
431 25350672 Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section. 3 0 1
432 15266443 Antibiotics for preventing recurrent urinary tract infection in non-pregnant women. 2 0 1
433 20166083 Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections. 2 0 1
434 11687183 Budesonide for chronic asthma in children and adults. 3 0 1
435 18425977 Ciclesonide versus other inhaled steroids for chronic asthma in children and adults. 2 0 1
425 22258983 Narrow band imaging versus conventional white light colonoscopy for the detection of colorectal polyps. 3 0 1
438 18843646 Fluticasone at different doses for chronic asthma in adults and children. 3 0 1
440 11869636 Fluticasone versus beclomethasone or budesonide for chronic asthma. 3 0 1
411 28707404 Sustained versus standard inflations during neonatal resuscitation to prevent mortality and improve respiratory outcomes. 4 0 1
412 27581993 Synchronized mechanical ventilation for respiratory support in newborn infants. 3 0 1
413 10796417 Synthetic surfactant for respiratory distress syndrome in preterm infants. 9 0 1
414 25217732 Techniques to ascertain correct endotracheal tube placement in neonates. 1 0 1
281 21154359 Inferior turbinate surgery for nasal obstruction in allergic rhinitis after failed medical treatment. 3 0 1
282 14583983 Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis. 2 0 1
283 10796150 Maternal antigen avoidance during pregnancy for preventing atopic disease in infants of women at high risk. 3 0 1
284 14583912 Maternal dietary antigen avoidance during pregnancy and/or lactation for preventing or treating atopic disease in the child. 4 0 1
285 22972039 Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. 4 0 1
288 17054183 Soy formula for prevention of allergy and food intolerance in infants. 4 0 1
289 21154351 Sublingual immunotherapy for allergic rhinitis. 2 0 1
290 26315994 Sublingual immunotherapy for asthma. 4 0 1
279 22513973 Helminth therapy (worms) for allergic rhinitis. 2 0 1
264 11687021 Techniques for preventing hypotension during spinal anaesthesia for caesarean section. 1 0 1
263 29022989 Prophylactic intravenous calcium therapy for exchange blood transfusion in the newborn. 2 0 1
262 26978162 Pre-hospital versus in-hospital initiation of cooling for survival and neuroprotection after out-of-hospital cardiac arrest. 2 0 1
235 17253502 Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia. 3 0 1
236 17253512 Passiflora for anxiety disorder. 6 0 1
238 27730622 Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults. 2 0 1
240 17054208 Valerian for anxiety disorders. 6 0 1
242 21975772 Interventions for prevention of neonatal hyperglycemia in very low birth weight infants. 2 0 1
243 20091569 Partial exchange transfusion to prevent neurodevelopmental disability in infants with polycythemia. 3 0 1
244 24052483 Active chest compression-decompression for cardiopulmonary resuscitation. 2 0 1
280 20614426 House dust mite avoidance measures for perennial allergic rhinitis. 3 0 1
278 23728641 Drug therapy for obstructive sleep apnoea in adults. 4 0 1
265 30820938 The use of ultrasound guidance for perioperative neuraxial and peripheral nerve blocks in children. 1 0 1
344 15106246 Treatment for swallowing difficulties (dysphagia) in chronic muscle disease. 4 0 1
415 26361135 Ultrasound guidance for upper and lower limb blocks. 1 0 1
416 22071820 Ultrasound use for the placement of haemodialysis catheters. 1 0 1
417 27544827 Venous cutdown versus the Seldinger technique for placement of totally implantable venous access ports. 1 0 1
418 29039883 Volume-targeted versus pressure-limited ventilation in neonates. 4 0 1
419 21069677 Volume-targeted versus pressure-limited ventilation in the neonate. 4 0 1
421 12076480 Dietary fibre for the prevention of colorectal adenomas and carcinomas. 2 0 1
347 25695214 Morita therapy for anxiety disorders in adults. 4 0 1
345 25692403 Cognitive behavioural therapy for anxiety disorders in children and adolescents. 4 0 1
343 27844477 Videolaryngoscopy versus direct laryngoscopy for adult patients requiring tracheal intubation. 2 0 1
277 15266430 Dietary salt reduction or exclusion for allergic asthma. 3 0 1
266 15495104 Betamimetics for inhibiting preterm labour. 3 0 1
267 18425866 Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. 1 0 1
268 12535425 Inhaled versus systemic corticosteroids for preventing chronic lung disease in ventilated very low birth weight preterm neonates. 1 0 1
269 21975769 Interventions for treatment of neonatal hyperglycemia in very low birth weight infants. 3 0 1
270 28141913 Systemic corticosteroid regimens for prevention of bronchopulmonary dysplasia in preterm infants. 4 0 1
271 17253469 Allergen injection immunotherapy for seasonal allergic rhinitis. 2 0 1
272 18425925 Anti-histamines for prolonged non-specific cough in children. 3 0 1
274 16625604 Capsaicin for allergic rhinitis in adults. 2 0 1
1482 30484282 Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease. 4 0 1
1483 26068956 Qigong for the primary prevention of cardiovascular disease. 1 0 1
1484 12917977 Reduced dietary salt for prevention of cardiovascular disease. 1 0 1
1396 28541603 Comparison of first-line chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for people with early unfavourable or advanced stage Hodgkin lymphoma. 5 0 1
1388 28752910 Antioxidants for female subfertility. 1 0 1
1423 20393968 Preconception lifestyle advice for people with subfertility. 2 0 1
1424 29139105 Preoperative medical therapy before surgery for uterine fibroids. 1 0 1
1425 11034767 Recombinant versus urinary follicle stimulating hormone for ovarian stimulation in assisted reproduction cycles. 2 0 1
1455 30027631 Blood pressure targets for the treatment of people with hypertension and cardiovascular disease. 4 0 1
1456 12519577 Chelation therapy for atherosclerotic cardiovascular disease. 1 0 1
1457 21249668 Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease. 4 0 1
1458 25474484 Co-enzyme Q10 supplementation for the primary prevention of cardiovascular disease. 1 0 1
1459 21833977 Considerable uncertainty remains in the evidence for primary prevention of cardiovascular disease. 1 0 1
1460 22071819 Creatine and creatine analogues in hypertension and cardiovascular disease. 4 0 1
1461 26758499 Dietary fibre for the primary prevention of cardiovascular disease. 1 0 1
1462 30480766 Ezetimibe for the prevention of cardiovascular disease and all-cause mortality events. 4 0 1
1463 27849333 Fibrates for primary prevention of cardiovascular disease events. 2 0 1
1454 14974027 Advice to reduce dietary salt for prevention of cardiovascular disease. 1 0 1
1464 26497361 Fibrates for secondary prevention of cardiovascular disease and stroke. 2 0 1
1466 23780706 Green and black tea for the primary prevention of cardiovascular disease. 5 0 1
1467 15846631 Hormone replacement therapy for preventing cardiovascular disease in post-menopausal women. 1 0 1
1468 25754617 Hormone therapy for preventing cardiovascular disease in post-menopausal women. 2 0 1
1470 28759107 Low glycaemic index diets for the prevention of cardiovascular disease. 3 0 1
1397 15674898 Depot versus daily administration of gonadotrophin releasing hormone agonist protocols for pituitary desensitization in assisted reproduction cycles. 2 0 1
1395 21833963 Comparison of chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for patients with early unfavourable or advanced stage Hodgkin lymphoma. 7 0 1
1487 10796866 Reduced or modified dietary fat for prevention of cardiovascular disease. 1 0 1
1394 25110856 Closure versus non-closure of the peritoneum at caesarean section: short- and long-term outcomes. 2 0 1
1422 19370571 Postoperative procedures for improving fertility following pelvic reproductive surgery. 2 0 1
1400 16625541 Fluid and pharmacological agents for adhesion prevention after gynaecological surgery. 1 0 1
1398 23440788 Depot versus daily administration of gonadotrophin-releasing hormone agonist protocols for pituitary down regulation in assisted reproduction cycles. 3 0 1
1377 27841439 Transcutaneous electrical stimulation (TES) for treatment of constipation in children. 2 0 1
1378 24096644 Transdermal fentanyl for cancer pain. 1 0 1
1379 25238582 Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents. 3 0 1
1380 11687009 What is the role of stimulant laxatives in the management of childhood constipation and soiling?. 1 0 1
1382 18843737 Acupuncture and assisted conception. 1 0 1
1383 23888428 Acupuncture and assisted reproductive technology. 1 0 1
1384 27136291 Acupuncture for polycystic ovarian syndrome. 15 0 1
1385 26608695 Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction. 1 0 1
1386 10796496 Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia. 2 0 1
1399 27296541 Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination. 2 0 1
1387 17943756 Antibiotics for incomplete abortion. 2 0 1
1389 30866036 Antioxidants for male subfertility. 1 0 1
1390 10796498 Bromocriptine for idiopathic oligo/asthenospermia. 5 0 1
1391 19821295 Clomiphene and anti-oestrogens for ovulation induction in PCOS. 3 0 1
1392 27976369 Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome. 16 0 1
1393 10908459 Clomiphene citrate for unexplained subfertility in women. 1 0 1
1471 30864165 Mediterranean-style diet for the primary and secondary prevention of cardiovascular disease. 2 0 1
1472 28455948 Mobile phone text messaging to improve medication adherence in secondary prevention of cardiovascular disease. 2 0 1
1473 29932455 Mobile phone-based interventions for improving adherence to medication prescribed for the primary prevention of cardiovascular disease in adults. 2 0 1
1475 26411417 Nut consumption for the primary prevention of cardiovascular disease. 1 0 1
1445 18843683 Interventions for unilateral refractive amblyopia. 1 0 1
1446 16034962 Screening for amblyopia in childhood. 1 0 1
1449 27236587 Systemic treatment for blepharokeratoconjunctivitis in children. 2 0 1
1450 28170093 Topical treatments for blepharokeratoconjunctivitis in children. 3 0 1
1478 30521670 Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. 2 0 1
1603 28756647 Mid-urethral sling operations for stress urinary incontinence in women. 1 0 1
1604 19821363 Minimally invasive synthetic suburethral sling operations for stress urinary incontinence in women. 1 0 1
1605 18425910 Oestrogens for preventing recurrent urinary tract infection in postmenopausal women. 1 0 1
1755 23450545 Partial liquid ventilation for the prevention of mortality and morbidity in paediatric acute lung injury and acute respiratory distress syndrome. 14 0 1
1757 26513128 Pharmacological interventions for cognitive decline in people with Down syndrome. 14 0 1
1759 21412918 Pharyngeal instillation of surfactant before the first breath for prevention of morbidity and mortality in preterm infants at risk of respiratory distress syndrome. 14 0 1
1760 26905470 Physiotherapy for pain and disability in adults with complex regional pain syndrome (CRPS) types I and II. 14 0 1
1761 22258957 Positive end expiratory pressure for preterm infants requiring conventional mechanical ventilation for respiratory distress syndrome or bronchopulmonary dysplasia. 15 0 1
1762 30820939 Positive end-expiratory pressure for preterm infants requiring conventional mechanical ventilation for respiratory distress syndrome or bronchopulmonary dysplasia. 16 0 1
1764 26350479 Post-exposure passive immunisation for preventing rubella and congenital rubella syndrome. 13 0 1
1765 25586462 Pressure-controlled versus volume-controlled ventilation for acute respiratory failure due to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). 14 0 1
1767 28770972 Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery for congenital heart disease. 15 0 1
1754 30321454 Parent-mediated interventions for promoting communication and language development in young children with Down syndrome. 14 0 1
1769 27855477 Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation. 14 0 1
1444 22513928 Interventions for unilateral and bilateral refractive amblyopia. 1 0 1
1443 25051925 Interventions for strabismic amblyopia. 3 0 1
1442 19821369 Conventional occlusion versus pharmacologic penalization for amblyopia. 1 0 1
1429 12804495 Reduction of the number of fetuses for women with triplet and higher order multiple pregnancies. 1 0 1
1476 15495044 Omega 3 fatty acids for prevention and treatment of cardiovascular disease. 1 0 1
1465 25267903 Fixed-dose combination therapy for the prevention of cardiovascular disease. 1 0 1
1453 23152231 Adenosine-diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2 diabetes mellitus. 6 0 1
1452 25267918 'Mediterranean' dietary pattern for the primary prevention of cardiovascular disease. 1 0 1
1451 19588363 Vision screening for amblyopia in childhood. 1 0 1
1426 27106604 Recombinant versus urinary human chorionic gonadotrophin for final oocyte maturation triggering in IVF and ICSI cycles. 4 0 1
1427 15846677 Recombinant versus urinary human chorionic gonadotrophin for ovulation induction in assisted conception. 1 0 1
1428 26544079 Reduction of the number of fetuses for women with a multiple pregnancy. 1 0 1
1430 27623210 Screening for genital chlamydia infection. 6 0 1
1441 26263202 Binocular versus standard occlusion or blurring treatment for unilateral amblyopia in children aged three to eight years. 3 0 1
1431 28112384 Surgery for tubal infertility. 2 0 1
1432 16856021 Surgical treatment of fibroids for subfertility. 1 0 1
1433 25528596 Synchronised approach for intrauterine insemination in subfertile couples. 2 0 1
1434 16625531 Techniques for pelvic surgery in subfertility. 1 0 1
1435 16855991 Techniques for surgical retrieval of sperm prior to ICSI for azoospermia. 2 0 1
1436 18425884 Techniques for surgical retrieval of sperm prior to intra-cytoplasmic sperm injection (ICSI) for azoospermia. 2 0 1
1437 25929235 Tubal flushing for subfertility. 1 0 1
1439 23076943 Corticosteroids as standalone or add-on treatment for sore throat. 1 0 1
1412 12519555 Laparoscopic surgery for subfertility associated with endometriosis. 1 0 1
1421 22696356 Peri-implantation glucocorticoid administration for assisted reproductive technology cycles. 1 0 1
1420 24482059 Ovulation triggers in anovulatory women undergoing ovulation induction. 3 0 1
1575 30312988 Vasodilators for women undergoing fertility treatment. 1 0 1
1582 23235594 Anticholinergic drugs versus non-drug active therapies for non-neurogenic overactive bladder syndrome in adults. 15 0 1
1583 17054163 Anticholinergic drugs versus non-drug active therapies for overactive bladder syndrome in adults. 2 0 1
1584 28742262 Bladder neck needle suspension for urinary incontinence in women. 1 0 1
1585 14973967 Bladder training for urinary incontinence in adults. 2 0 1
1586 22161451 Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women. 1 0 1
1587 11406013 Conservative management for post prostatectomy urinary incontinence. 1 0 1
1588 25602133 Conservative management for postprostatectomy urinary incontinence. 1 0 1
1579 23818069 Acupuncture for stress urinary incontinence in adults. 1 0 1
1589 10796825 Conservative management of post prostatectomy incontinence. 1 0 1
1591 29271482 Electrical stimulation with non-implanted devices for stress urinary incontinence in women. 1 0 1
1593 23740763 Electrical stimulation with non-implanted electrodes for urinary incontinence in men. 1 0 1
1594 26222251 Endoscopic third ventriculostomy (ETV) for idiopathic normal pressure hydrocephalus (iNPH). 3 0 1
1595 19160176 Episiotomy for vaginal birth. 1 0 1
1596 21735442 Feedback or biofeedback to augment pelvic floor muscle training for urinary incontinence in women. 1 0 1
1597 15106179 Habit retraining for the management of urinary incontinence in adults. 1 0 1
1598 24497276 Hyaluronidase for reducing perineal trauma. 1 0 1
1599 30706461 Interventions for treating urinary incontinence after stroke in adults. 2 0 1
1600 30059147 Laparoscopic colposuspension for urinary incontinence in women. 1 0 1
1590 23235587 Drugs for nocturnal enuresis in children (other than desmopressin and tricyclics). 2 0 1
1581 28759116 Anterior vaginal repair for urinary incontinence in women. 1 0 1
1580 16034867 Adrenergic drugs for urinary incontinence in adults. 2 0 1
1551 28072907 Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease. 4 0 1
1499 26389791 Vitamin K for the primary prevention of cardiovascular disease. 1 0 1
1490 25267917 Selenium supplementation for the primary prevention of cardiovascular disease. 1 0 1
1491 26905928 Sexual counselling for sexual problems in patients with cardiovascular disease. 1 0 1
1492 25855824 Should hormone therapy be recommended for prevention of cardiovascular disease? 1 0 1
1494 25278808 Supplemental plant sterols and stanols for serum cholesterol and cardiovascular disease. 1 0 1
1495 26824223 Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease. 1 0 1
1510 12804396 Risperidone versus typical antipsychotic medication for schizophrenia. 1 0 1
1496 24715694 Tai chi for primary prevention of cardiovascular disease. 1 0 1
1498 28301692 Vitamin C supplementation for the primary prevention of cardiovascular disease. 2 0 1
1500 28836672 Whole grain cereals for the primary or secondary prevention of cardiovascular disease. 3 0 1
1548 23152212 Recombinant human insulin-like growth factor I (rhIGF-I) for the treatment of amyotrophic lateral sclerosis/motor neuron disease. 3 0 1
1502 20091663 Adenoidectomy for recurrent or chronic nasal symptoms in children. 3 0 1
1504 12137610 Antibiotics for the common cold. 2 0 1
1505 17054180 Formulas containing hydrolysed protein for prevention of allergy and food intolerance in infants. 4 0 1
1506 28293923 Infant formulas containing hydrolysed protein for prevention of allergic disease and food allergy. 5 0 1
1507 22336840 Interventions for atrophic rhinitis. 3 0 1
1508 16625573 Metrifonate for Alzheimer's disease. 4 0 1
1497 25436436 Transcendental meditation for the primary prevention of cardiovascular disease. 1 0 1
1547 17943766 Recombinant human insulin-like growth factor I (rhIGF-I) for amyotrophic lateral sclerosis/motor neuron disease. 3 0 1
1578 17443507 Absorbent products for light urinary incontinence in women. 1 0 1
1574 26984325 Ultrasound versus 'clinical touch' for catheter guidance during embryo transfer in women. 1 0 1
1419 10796697 Ovulation suppression for endometriosis. 2 0 1
1552 23728653 Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease. 3 0 1
1479 30488422 Omega-6 fats for the primary and secondary prevention of cardiovascular disease. 2 0 1
1477 26571451 Omega 6 fatty acids for the primary prevention of cardiovascular disease. 1 0 1
1402 12535497 Human menopausal gonadotropin versus recombinant follicle stimulation hormone for ovarian stimulation in assisted reproductive cycles. 2 0 1
1403 22513911 In vitro fertilisation for unexplained subfertility. 1 0 1
1404 19160291 In vitro maturation in sub fertile women with polycystic ovarian syndrome undergoing assisted reproduction. 2 0 1
1405 12804403 Intra-cytoplasmic sperm injection versus conventional techniques for oocyte insemination during in vitro fertilisation in patients with non-male subfertility. 2 0 1
1406 10796764 Intra-cytoplasmic sperm injection versus partial zona dissection, subzonal insemination and conventional techniques for oocyte insemination during in vitro fertilisation. 1 0 1
1407 19370567 Intra-uterine insemination versus fallopian tube sperm perfusion for non-tubal infertility. 1 0 1
1408 16235303 Intra-uterine insemination versus timed intercourse for cervical hostility in subfertile couples. 2 0 1
1409 10796709 Intra-uterine versus cervical insemination of donor sperm for subfertility. 1 0 1
1410 15266448 Intrauterine insemination versus fallopian tube sperm perfusion for non tubal infertility. 1 0 1
1401 17943837 Gonadotrophins for idiopathic male factor subfertility. 2 0 1
1411 24174382 Intrauterine insemination versus fallopian tube sperm perfusion for non-tubal infertility. 2 0 1
1413 23076922 Long versus short course treatment with metformin and clomiphene citrate for ovulation induction in women with PCOS. 3 0 1
1414 25406011 Metformin treatment before and during IVF or ICSI in women with polycystic ovary syndrome. 16 0 1
1415 29274129 Newborn screening for galactosaemia. 2 0 1
1416 12918007 Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes. 3 0 1
1417 10796691 Oil-soluble versus water-soluble media for assessing tubal patency with hysterosalpingography or laparoscopy in subfertile women. 1 0 1
1418 15674894 Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation. 3 0 1
1601 21735436 Low-dose rate brachytherapy for men with localized prostate cancer. 2 0 1
1480 28453187 PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease. 2 0 1
1573 15846676 Tubal flushing for subfertility. 1 0 1
1562 17943898 Chinese herbal medicines in the treatment of ectopic pregnancy. 1 0 1
1554 19160266 Treatment for familial amyotrophic lateral sclerosis/motor neuron disease. 3 0 1
1555 21563158 Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis. 5 0 1
1556 22336799 Treatment for spasticity in amyotrophic lateral sclerosis/motor neuron disease. 3 0 1
1557 29293261 Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease. 4 0 1
1558 25561409 Adhesion prevention agents for gynaecological surgery: an overview of Cochrane reviews. 1 0 1
1559 29489026 Application of seminal plasma to female genital tract prior to embryo transfer in assisted reproductive technology cycles (IVF, ICSI and frozen embryo transfer). 1 0 1
1560 27807847 Aspirin for in vitro fertilisation. 1 0 1
1561 21735404 Chinese herbal medicine in the treatment of ectopic pregnancy. 1 0 1
1563 27976360 Day three versus day two embryo transfer following in vitro fertilization or intracytoplasmic sperm injection. 1 0 1
1572 10796702 Techniques for pelvic surgery in subfertility. 1 0 1
1564 20091563 Interventions for 'poor responders' to controlled ovarian hyper stimulation (COH) in in-vitro fertilisation (IVF). 1 0 1
1565 17253448 Interventions for tubal ectopic pregnancy. 1 0 1
1566 17943739 Intra-uterine insemination for male subfertility. 2 0 1
1567 30341915 Intrauterine administration of human chorionic gonadotropin (hCG) for subfertile women undergoing assisted reproduction. 1 0 1
1568 26171903 Long-acting FSH versus daily FSH for women undergoing assisted reproduction. 2 0 1
1569 29547689 Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies. 1 0 1
1570 11686974 Periconceptional supplementation with folate and/or multivitamins for preventing neural tube defects. 1 0 1
1571 20091531 Surgical treatment for tubal disease in women due to undergo in vitro fertilisation. 1 0 1
3185 18254030 Antidepressant drugs for narcolepsy. 2 0 1
3586 22972084 Restriction of oral intake of water for aspiration lung disease in children. 1 0 1
3183 30311942 Type II or type III radical hysterectomy compared to chemoradiotherapy as a primary intervention for stage IB2 cervical cancer. 2 0 1
2043 12519550 Magnesium sulphate for preventing preterm birth in threatened preterm labour. 1 0 1
2046 27022888 Melatonin for women in pregnancy for neuroprotection of the fetus. 1 0 1
2047 29926474 Neonatal interventions for preventing cerebral palsy: an overview of Cochrane Systematic Reviews. 8 0 1
2048 25768935 Pharmacological interventions for pain in children and adolescents with life-limiting conditions. 3 0 1
2049 11405952 Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage. 1 0 1
2050 24307518 Prophylactic antibiotics for inhibiting preterm labour with intact membranes. 1 0 1
1962 17943843 Family interventions for bipolar disorder. 1 0 1
2077 21833964 Psychosocial interventions for premature ejaculation. 2 0 1
1961 24158923 Dietary supplements for preventing postnatal depression. 4 0 1
1959 18254070 Antiglucocorticoid treatments for mood disorders. 1 0 1
1877 17054157 Anabolic-androgenic steroids for alcoholic liver disease. 4 0 1
1878 16437522 Antiangiogenic therapy with interferon alfa for neovascular age-related macular degeneration. 2 0 1
1879 24590589 Antibiotic prophylaxis for preventing post solid organ transplant tuberculosis. 3 0 1
1880 24880007 Antibody induction versus corticosteroid induction for liver transplant recipients. 3 0 1
1881 24901467 Antibody induction versus placebo, no induction, or another type of antibody induction for liver transplant recipients. 3 0 1
1882 21412909 Antioxidant supplements for liver diseases. 4 0 1
1884 21154370 Antiviral prophylactic intervention for chronic hepatitis C virus in patients undergoing liver transplantation. 2 0 1
1886 20091608 Antiviral therapy for recurrent liver graft infection with hepatitis C virus. 2 0 1
1888 17054206 Bicyclol for chronic hepatitis B. 3 0 1
1876 24937404 Aminoadamantanes versus other antiviral drugs for chronic hepatitis C. 5 0 1
2044 19160238 Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus. 4 0 1
2042 19160189 Late (>7 days) postnatal corticosteroids for chronic lung disease in preterm infants. 4 0 1
2072 22161390 Complementary and miscellaneous interventions for nocturnal enuresis in children. 1 0 1
2040 24825542 Late (> 7 days) postnatal corticosteroids for chronic lung disease in preterm infants. 3 0 1
2074 12137645 Desmopressin for nocturnal enuresis in children. 1 0 1
2075 15106210 Simple behavioural and physical interventions for nocturnal enuresis in children. 1 0 1
2076 26789925 Tricyclic and related drugs for nocturnal enuresis in children. 2 0 1
2066 26602956 Use of biochemical tests of placental function for improving pregnancy outcome. 3 0 1
2053 22258977 Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants. 2 0 1
2052 21154342 Prophylactic methylxanthines for endotracheal extubation in preterm infants. 5 0 1
2051 12137607 Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. 1 0 1
2027 17443595 Early developmental intervention programs post hospital discharge to prevent motor and cognitive impairments in preterm infants. 1 0 1
2028 12535402 Early postnatal (<96 hours) corticosteroids for preventing chronic lung disease in preterm infants. 7 0 1
2029 15106166 Early volume expansion for prevention of morbidity and mortality in very preterm infants. 1 0 1
2030 28398697 Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants. 3 0 1
2031 25785789 Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. 6 0 1
2032 28602046 Exercise interventions for cerebral palsy. 1 0 1
2033 28762235 Fluid supplementation for neonatal unconjugated hyperbilirubinaemia. 3 0 1
2034 23900969 Gastrostomy feeding versus oral feeding alone for children with cerebral palsy. 1 0 1
2035 29551014 Immunoglobulin for alloimmune hemolytic disease in neonates. 4 0 1
2036 28191626 Intermittent auscultation (IA) of fetal heart rate in labour for fetal well-being. 1 0 1
2038 23076958 Interventions for oropharyngeal dysphagia in children with neurological impairment. 5 0 1
2039 26563961 Intrathecal baclofen for treating spasticity in children with cerebral palsy. 1 0 1
1889 17253534 Bicyclol for chronic hepatitis C. 3 0 1
1891 10796646 Blood transfusion for treating malarial anaemia. 3 0 1
1892 27271960 Booster dose vaccination for preventing hepatitis B. 2 0 1
1893 17054264 Caesarean section versus vaginal delivery for preventing mother to infant hepatitis C virus transmission. 2 0 1
1865 10796158 Oxytocin for promoting successful lactation. 1 0 1
1866 21069690 Clozapine versus other atypical antipsychotics for schizophrenia. 2 0 1
1867 17443558 Dipyrone for acute primary headaches. 2 0 1
1868 29737522 Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia. 4 0 1
1869 18646130 Pharmacological interventions for clozapine-induced hypersalivation. 1 0 1
1870 20824835 Single dose dipyrone for acute postoperative pain. 3 0 1
1871 12519613 Single dose dipyrone for acute renal colic pain. 2 0 1
1872 11687057 Single-dose dipyrone for acute postoperative pain. 3 0 1
1862 26373268 Wound-care teams for preventing and treating pressure ulcers. 1 0 1
1902 12804461 Dopamine agonists for cocaine dependence. 3 0 1
1903 24101439 Early and late renal adverse effects after potentially nephrotoxic treatment for childhood cancer. 6 0 1
1904 22972122 Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin treatment for 48 weeks in chronic hepatitis C genotype 1 infected slow-responder adult patients. 2 0 1
1937 28368093 Pharmacological interventions for alcoholic liver disease (alcohol-related liver disease): an attempted network meta-analysis. 6 0 1
1938 21491412 Phyllanthus species for chronic hepatitis B virus infection. 2 0 1
1939 23633363 Phyllanthus species versus antiviral drugs for chronic hepatitis B virus infection. 2 0 1
1940 28444987 Platelet count, spleen length, and platelet count-to-spleen length ratio for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis. 6 0 1
1942 30865287 Probiotics to prevent infantile colic. 5 0 1
1943 21678335 Propylthiouracil for alcoholic liver disease. 5 0 1
1944 30521696 Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users. 3 0 1
1864 15266468 Scopolamine for preventing and treating motion sickness. 1 0 1
1860 28225152 Topical phenytoin for treating pressure ulcers. 1 0 1
1874 22972059 Alpha-foetoprotein and/or liver ultrasonography for screening of hepatocellular carcinoma in patients with chronic hepatitis B. 5 0 1
1875 24793264 Aminoadamantanes for chronic hepatitis C. 2 0 1
1894 12076433 Carbamazepine for cocaine dependence. 3 0 1
1895 25613473 Cell salvage in emergency trauma surgery. 1 0 1
1896 11406038 Chinese medicinal herbs for asymptomatic carriers of hepatitis B virus infection. 4 0 1
1897 11279742 Chinese medicinal herbs for chronic hepatitis B. 2 0 1
1898 11687017 Colchicine for alcoholic and non-alcoholic liver fibrosis and cirrhosis. 2 0 1
1899 22513932 Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB). 6 0 1
1890 17943781 Bile acids for viral hepatitis. 9 0 1
1900 29190036 Devices for preventing percutaneous exposure injuries caused by needles in healthcare personnel. 2 0 1
1873 12804438 Alpha-fetoprotein and/or liver ultrasonography for liver cancer screening in patients with chronic hepatitis B. 6 0 1
1859 30307602 Support surfaces for treating pressure ulcers. 1 0 1
1848 29025198 Foam dressings for treating pressure ulcers. 1 0 1
1849 26081072 Massage therapy for preventing pressure ulcers. 1 0 1
1850 25992684 Negative pressure wound therapy for treating pressure ulcers. 1 0 1
1852 30536917 Organisation of health services for preventing and treating pressure ulcers. 1 0 1
1853 25019295 Phototherapy for treating pressure ulcers. 1 0 1
1854 27919120 Reconstructive surgery for treating pressure ulcers. 1 0 1
1855 24700291 Repositioning for pressure ulcer prevention in adults. 1 0 1
1857 30702158 Risk assessment tools for the prevention of pressure ulcers. 1 0 1
2073 14974076 Complex behavioural and educational interventions for nocturnal enuresis in children. 1 0 1
2070 23235630 Interventions to facilitate return to work in adults with adjustment disorders. 1 0 1
1946 19821346 Ribavirin monotherapy for chronic hepatitis C. 2 0 1
2621 29861660 Computer and mobile technology interventions to promote medication adherence and disease management in people with thalassemia. 2 0 1
2317 22071816 Hydralazine for essential hypertension. 8 0 1
2316 30102428 Hospitalisation in short-stay units for adults with internal medicine diseases and conditions. 2 0 1
2315 25590290 Homocysteine-lowering interventions for preventing cardiovascular events. 1 0 1
1995 30521681 Reflectance confocal microscopy for diagnosing cutaneous melanoma in adults. 2 0 1
1996 30521687 Reflectance confocal microscopy for diagnosing keratinocyte skin cancers in adults. 5 0 1
1998 30521685 Smartphone applications for triaging adults with skin lesions that are suspicious for melanoma. 2 0 1
2003 30521686 Teledermatology for diagnosing skin cancer in adults. 6 0 1
2004 30521688 Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults. 4 0 1
2005 30521684 Visual inspection for diagnosing cutaneous melanoma in adults. 2 0 1
2006 25387103 Wound drainage following groin dissection for malignant disease in adults. 3 0 1
2007 23740536 Magnesium for alcohol withdrawal. 3 0 1
2008 10796733 Cognitive behaviour therapy for adults with chronic fatigue syndrome. 1 0 1
1994 30521690 Optical coherence tomography for diagnosing skin cancer in adults. 6 0 1
2010 19821361 Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome. 1 0 1
2013 28399330 Arginine supplementation for prevention of necrotising enterocolitis in preterm infants. 1 0 1
2014 24500892 Betamimetics for inhibiting preterm labour. 2 0 1
2015 20091546 Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy (UPDATE). 2 0 1
2016 15495055 Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy. 2 0 1
2017 10796784 Botulinum toxin type A in the treatment of lower limb spasticity in cerebral palsy. 1 0 1
2655 18843734 Antiviral therapy for Ramsay Hunt syndrome (herpes zoster oticus with facial palsy) in adults. 2 0 1
2620 23807756 Zinc supplements for treating thalassaemia and sickle cell disease. 1 0 1
2069 29683474 Antidepressants for the treatment of depression in people with cancer. 4 0 1
2619 28105733 Vitamin D supplementation for sickle cell disease. 7 0 1
2622 22336831 Deferasirox for managing iron overload in people with thalassaemia. 1 0 1
2598 26451693 Laser therapy for retinopathy in sickle cell disease. 4 0 1
2599 26684281 Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease. 1 0 1
2601 10796837 Neonatal screening for sickle cell disease. 2 0 1
2602 16625580 Pain management for sickle cell disease. 2 0 1
2603 29446825 Phytomedicines (medicines derived from plants) for sickle cell disease. 2 0 1
2604 26869149 Piracetam for reducing the incidence of painful sickle cell disease crises. 1 0 1
2605 14974042 Pneumococcal vaccines for sickle cell disease. 1 0 1
2606 27049331 Preoperative blood transfusions for sickle cell disease. 4 0 1
2607 28994899 Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease. 2 0 1
2608 10796098 Prophylactic versus selective blood transfusion for sickle cell anaemia during pregnancy. 1 0 1
2610 30067867 Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews. 6 0 1
2611 27198469 Regular long-term red blood cell transfusions for managing chronic chest complications in sickle cell disease. 3 0 1
2612 29112240 Splenectomy versus conservative management for acute sequestration crises in people with sickle cell disease. 2 0 1
2613 17443618 Steroid hormones for contraception in women with sickle cell disease. 1 0 1
2614 30578732 Transfusion of red blood cells stored for shorter versus longer duration for all conditions. 2 0 1
2616 27103509 Treatment of dental complications in sickle cell disease. 2 0 1
2617 28926088 Treatments for priapism in boys and men with sickle cell disease. 4 0 1
2618 30521695 Vaccines for preventing invasive salmonella infections in people with sickle cell disease. 2 0 1
2018 17443542 Constraint-induced movement therapy in the treatment of the upper limb in children with hemiplegic cerebral palsy. 1 0 1
2019 28157275 Continuous cardiotocography (CTG) as a form of electronic fetal monitoring (EFM) for fetal assessment during labour. 1 0 1
2020 11405949 Continuous electronic heart rate monitoring for fetal assessment during labor. 1 0 1
2021 25523279 Creatine for women in pregnancy for neuroprotection of the fetus. 1 0 1
1987 30521682 Dermoscopy, with and without visual inspection, for diagnosing melanoma in adults. 2 0 1
1988 30521689 Exfoliative cytology for diagnosing basal cell carcinoma and other skin cancers in adults. 5 0 1
1976 22161389 Tiagabine in the maintenance treatment of bipolar disorder. 1 0 1
2023 24825456 Early (< 8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. 6 0 1
2025 23235624 Early developmental intervention programmes post-hospital discharge to prevent motor and cognitive impairments in preterm infants. 1 0 1
2026 26597166 Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants. 2 0 1
2055 28384379 Repeated lumbar or ventricular punctures in newborns with intraventricular haemorrhage. 2 0 1
2056 11279684 Repeated lumbar or ventricular punctures in newborns with intraventricular hemorrhage. 2 0 1
2057 26524348 Sleep positioning systems for children with cerebral palsy. 1 0 1
2059 16235349 Surgical treatment for the thumb-in-palm deformity in patients with cerebral palsy. 2 0 1
2060 17253539 The effect of inotropes on morbidity and mortality in preterm infants with low systemic or organ blood flow. 3 0 1
2061 10796406 Thyroid hormone for preventing of neurodevelopmental impairment in preterm infants. 4 0 1
2062 11687092 Thyroid hormones for preventing neurodevelopmental impairment in preterm infants. 4 0 1
2063 28755534 Treadmill interventions in children under six years of age at risk of neuromotor delay. 4 0 1
2064 22161449 Treadmill interventions with partial body weight support in children under six years of age at risk of neuromotor delay. 3 0 1
2054 17253571 Prophylactic postnatal thyroid hormones for prevention of morbidity and mortality in preterm infants. 6 0 1
2065 29763510 Trihexyphenidyl for dystonia in cerebral palsy. 4 0 1
2067 20091505 Vitamin K prior to preterm birth for preventing neonatal periventricular haemorrhage. 2 0 1
2068 20238354 Antidepressants for depression in physically ill people. 2 0 1
1986 23740609 Cryotherapy for liver metastases. 5 0 1
1985 30521691 Computer-assisted diagnosis techniques (dermoscopy and spectroscopy-based) for diagnosing skin cancer in adults. 6 0 1
1984 17253556 Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma. 1 0 1
1968 11687035 Lithium for maintenance treatment of mood disorders. 2 0 1
2011 15846632 Air versus oxygen for resuscitation of infants at birth. 6 0 1
2022 12535401 Delayed (>3 weeks) postnatal corticosteroids for chronic lung disease in preterm infants. 5 0 1
1993 17943854 Interventions for preventing non-melanoma skin cancers in high-risk groups. 2 0 1
1989 30521683 High-frequency ultrasound for diagnosing skin cancer in adults. 6 0 1
1963 16856043 Haloperidol alone or in combination for acute mania. 2 0 1
1964 26374731 Hemodialysis for lithium poisoning. 1 0 1
1965 17253526 Interventions for helping people recognise early signs of recurrence in bipolar disorder. 1 0 1
1966 27668891 Interventions to encourage uptake of cancer screening for people with severe mental illness. 2 0 1
1971 22161387 Oxcarbazepine for acute affective episodes in bipolar disorder. 2 0 1
1982 24132760 Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder. 1 0 1
1972 18254071 Oxcarbazepine in the maintenance treatment of bipolar disorder. 1 0 1
1973 17054229 Risperidone in long-term treatment for bipolar disorder. 2 0 1
1974 29355909 Risperidone versus other antipsychotics for people with severe mental illness and co-occurring substance misuse. 3 0 1
1990 29247502 Immunotherapy (excluding checkpoint inhibitors) for stage I to III non-small cell lung cancer treated with surgery or radiotherapy with curative intent. 3 0 1
1975 23235614 Tiagabine for acute affective episodes in bipolar disorder. 1 0 1
1977 16856081 Tiagabine in the maintenance treatment of bipolar disorders. 1 0 1
1978 16856056 Tiagabine in the treatment of acute affective episodes in bipolar disorder: efficacy and acceptability. 2 0 1
1979 27591453 Topiramate for acute affective episodes in bipolar disorder in adults. 1 0 1
1945 30941748 Radix Sophorae flavescentis versus no intervention or placebo for chronic hepatitis B. 6 0 1
1936 28285495 Pharmacological interventions for acute hepatitis C infection: an attempted network meta-analysis. 5 0 1
3182 24874726 Surgical treatment of stage IA2 cervical cancer. 1 0 1
2265 11687190 Anticoagulation for heart failure in sinus rhythm. 3 0 1
2267 22161375 Antiplatelet agents and anticoagulants for hypertension. 4 0 1
2268 11687189 Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm. 1 0 1
2269 27629776 Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm. 4 0 1
2270 21678330 Antithrombotic agents for preventing thrombosis after infrainguinal arterial bypass surgery. 2 0 1
2271 28102899 B-type natriuretic peptide-guided treatment for heart failure. 1 0 1
2272 27764523 Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults. 4 0 1
2273 25879091 Beta-adrenergic blockers for perioperative cardiac risk reduction in people undergoing vascular surgery. 2 0 1
2274 29952095 Beta-blockers and inhibitors of the renin-angiotensin aldosterone system for chronic heart failure with preserved ejection fraction. 1 0 1
2275 26820557 Beta-blockers for congestive heart failure in children. 2 0 1
2276 25411555 Beta-blockers for heart failure. 2 0 1
2279 29998494 Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion-dependent beta thalassaemia. 3 0 1
2280 20687074 Calcium channel blockers versus other classes of drugs for hypertension. 2 0 1
2281 25503364 Cardiac rehabilitation for people with heart disease: an overview of Cochrane systematic reviews. 1 0 1
2282 11406056 Cardioselective beta-blocker use in patients with reversible airway disease. 3 0 1
2284 12519582 Cardioselective beta-blockers for reversible airway disease. 2 0 1
2285 22972058 Clinical service organisation for heart failure. 1 0 1
2286 24049047 Coenzyme Q10 for heart failure. 2 0 1
2205 16034977 Carbamazepine for acute and chronic pain. 3 0 1
2204 29939406 Botulinum toxins for the prevention of migraine in adults. 1 0 1
2266 16625532 Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. 2 0 1
2264 25820938 Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation. 2 0 1
2294 28489279 Dipeptidyl-peptidase (DPP)-4 inhibitors and glucagon-like peptide (GLP)-1 analogues for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased risk for the development of type 2 diabetes mellitus. 3 0 1
2263 25267889 Angiotensin receptor blockers for heart failure. 1 0 1
2296 30620776 Disease management interventions for heart failure. 2 0 1
2299 15266549 Effect of longer-term modest salt reduction on blood pressure. 1 0 1
2300 23744578 Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers. 3 0 1
2301 23450552 Endothelin receptor antagonists for pulmonary arterial hypertension. 4 0 1
2290 19821337 Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy. 1 0 1
2302 28245343 Eplerenone for hypertension. 3 0 1
2304 22895912 Evidence-informed policy decisions on remote monitoring for chronic heart failure. Is it enough? 1 0 1
2305 20393935 Exercise based rehabilitation for heart failure. 1 0 1
2307 30270428 Exercise-based cardiac rehabilitation for people with implantable ventricular assist devices. 2 0 1
2308 11034729 Exercise-based rehabilitation for coronary heart disease. 1 0 1
2310 30480768 First-line drugs inhibiting the renin angiotensin system versus other first-line antihypertensive drug classes for hypertension. 3 0 1
2311 27482837 Guanylate cyclase stimulators for pulmonary hypertension. 4 0 1
2312 18254076 Hawthorn extract for treating chronic heart failure. 1 0 1
2313 28665511 Home-based versus centre-based cardiac rehabilitation. 1 0 1
2314 19821378 Homocysteine lowering interventions for preventing cardiovascular events. 2 0 1
2303 20091643 Erythropoiesis-stimulating agents for anaemia in chronic heart failure patients. 3 0 1
2289 20464735 Different anthracycline derivates for reducing cardiotoxicity in cancer patients. 1 0 1
2288 16034890 Continuous infusion versus bolus injection of loop diuretics in congestive heart failure. 2 0 1
2287 26816301 Colchicine for prevention of cardiovascular events. 1 0 1
2202 28084009 Aspirin for acute treatment of episodic tension-type headache in adults. 1 0 1
2201 23797674 Antiepileptics other than gabapentin, pregabalin, topiramate, and valproate for the prophylaxis of episodic migraine in adults. 1 0 1
2119 15266455 Pit and fissure sealants for preventing dental decay in the permanent teeth of children and adolescents. 1 0 1
2121 26780162 Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents. 1 0 1
2088 23728699 Lifestyle interventions for chronic gout. 2 0 1
2089 20238366 Pegloticase for chronic gout. 4 0 1
2090 18425920 Systemic corticosteroids for acute gout. 1 0 1
2091 25392987 Uricosuric medications for chronic gout. 2 0 1
2092 26954446 Adhesively bonded versus non-bonded amalgam restorations for dental caries. 1 0 1
2093 24343855 Antibacterial agents in composite restorations for the prevention of dental caries. 1 0 1
2095 29284075 Atraumatic restorative treatment versus conventional restorative treatment for managing dental caries. 1 0 1
2097 25867816 Chlorhexidine treatment for the prevention of dental caries in children and adolescents. 1 0 1
2098 14973992 Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride for preventing dental caries in children and adolescents. 1 0 1
2099 27629283 Community-based population-level interventions for promoting child oral health. 2 0 1
2101 26334643 Fluoridated milk for preventing dental caries. 1 0 1
2104 29059464 Fluoride supplementation (with tablets, drops, lozenges or chewing gum) in pregnant women for preventing dental caries in the primary teeth of their children. 1 0 1
2105 22161414 Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children. 1 0 1
2106 12535435 Fluoride toothpastes for preventing dental caries in children and adolescents. 1 0 1
2108 30829399 Fluoride toothpastes of different concentrations for preventing dental caries. 1 0 1
2109 23846772 Fluoride varnishes for preventing dental caries in children and adolescents. 1 0 1
2110 30968949 Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal diseases and dental caries. 3 0 1
2111 24353078 Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults. 3 0 1
2112 14973991 One topical fluoride (toothpastes, or mouthrinses, or gels, or varnishes) versus another for preventing dental caries in children and adolescents. 1 0 1
2115 23543523 Operative caries management in adults and children. 1 0 1
2116 22895934 Optimal duration of exclusive breastfeeding. 2 0 1
2117 15266519 Ozone therapy for the treatment of dental caries. 1 0 1
2129 24310847 Triclosan/copolymer containing toothpastes for oral health. 5 0 1
2122 23728691 Primary school-based behavioural interventions for preventing caries. 1 0 1
2123 29852056 Pulp treatment for extensive decay in primary teeth. 1 0 1
2124 10796172 Pyridoxine (vitamin B6) supplementation in pregnancy. 1 0 1
2125 17943814 Recall intervals for oral health in primary care patients. 5 0 1
2126 23543512 Sealants for preventing dental decay in the permanent teeth. 1 0 1
2127 29495063 Slow-release fluoride devices for the control of dental decay. 1 0 1
2128 14583954 Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and adolescents. 1 0 1
2118 28759120 Pit and fissure sealants for preventing dental decay in permanent teeth. 1 0 1
2131 21975786 Allogeneic hematopoietic cell transplantation for adult acute lymphoblastic leukemia (ALL) in first complete remission. 2 0 1
2130 26092033 Water fluoridation for the prevention of dental caries. 2 0 1
2133 14583971 Antidepressants versus placebo for people with bulimia nervosa. 1 0 1
2134 11687197 Antidepressants versus psychological treatments and their combination for bulimia nervosa. 1 0 1
2135 22161411 Adjuvant radiotherapy following radical prostatectomy for prostate cancer. 1 0 1
2136 25379840 Anaesthetic techniques for risk of malignant tumour recurrence. 1 0 1
2137 29278410 Bisphosphonates for advanced prostate cancer. 5 0 1
2138 17054249 Chemotherapy for hormone-refractory prostate cancer. 2 0 1
2139 17636783 Cryotherapy for localised prostate cancer. 4 0 1
2140 11686990 Decision aids for people facing health treatment or screening decisions. 1 0 1
2295 20091507 Discharge planning from hospital to home. 1 0 1
2293 24771511 Digitalis for treatment of heart failure in patients in sinus rhythm. 3 0 1
1947 20091577 Ribavirin plus interferon versus interferon for chronic hepatitis C. 2 0 1
1919 12076394 Interferon for interferon naive patients with chronic hepatitis C. 2 0 1
1921 26287983 Interventions for dialysis patients with hepatitis C virus (HCV) infection. 5 0 1
1922 27513591 Isolation as a strategy for controlling the transmission of hepatitis C virus (HCV) infection in haemodialysis units. 4 0 1
1923 20614442 Lamivudine or adefovir dipivoxil alone or combined with immunoglobulin for preventing hepatitis B recurrence after liver transplantation. 4 0 1
1924 22161435 Lamivudine with or without adefovir dipivoxil for postoperative hepatocellular carcinoma. 4 0 1
1925 11687177 Medicinal herbs for hepatitis C virus infection. 2 0 1
1927 30091147 Needle size for vaccination procedures in children and adolescents. 5 0 1
1928 28922449 Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs. 2 0 1
1929 24706397 Nitazoxanide for chronic hepatitis C. 6 0 1
1930 22592729 Nutritional support for liver disease. 7 0 1
1931 24585451 Peginterferon alpha-2a versus peginterferon alpha-2b for chronic hepatitis C. 2 0 1
1932 24585509 Peginterferon plus ribavirin versus interferon plus ribavirin for chronic hepatitis C. 6 0 1
1960 28303578 Compulsory community and involuntary outpatient treatment for people with severe mental disorders. 1 0 1
2078 21328302 Screening for testicular cancer. 3 0 1
2079 29957821 Immunosuppressive treatment for proliferative lupus nephritis. 4 0 1
2082 25314636 Allopurinol for chronic gout. 2 0 1
2237 25931277 Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) for the prevention of tension-type headache in adults. 1 0 1
2238 27096578 Single dose dipyrone (metamizole) for acute postoperative pain in adults. 2 0 1
2239 26171993 Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults. 1 0 1
2240 25927097 Single dose oral ibuprofen plus codeine for acute postoperative pain in adults. 1 0 1
1920 23440791 Interferon for interferon nonresponding and relapsing patients with chronic hepatitis C. 5 0 1
1918 11869573 Interferon for acute hepatitis C. 2 0 1
2292 15106182 Digitalis for treatment of congestive heart failure in patients in sinus rhythm. 3 0 1
1916 19370595 Immunoglobulins for preventing hepatitis A. 2 0 1
1949 11869633 Ribavirin with or without alpha interferon versus no intervention, placebo or alpha interferon for chronic hepatitis C. 2 0 1
1950 16034852 Sequential combination of glucocorticosteroids and alfa interferon versus alfa interferon alone for HBeAg-positive chronic hepatitis B. 2 0 1
1951 27490232 Statins for age-related macular degeneration. 4 0 1
1952 25612182 Transient elastography for diagnosis of stages of hepatic fibrosis and cirrhosis in people with alcoholic liver disease. 4 0 1
1953 25525951 Treatment for cryoglobulinemic and non-cryoglobulinemic peripheral neuropathy associated with hepatitis C virus infection. 5 0 1
1954 26934429 Ultrasonography for diagnosis of alcoholic cirrhosis in people with alcoholic liver disease. 6 0 1
1956 29099543 Vitamin D supplementation for chronic liver diseases in adults. 8 0 1
1957 17943849 Bisphosphonate therapy for children and adolescents with secondary osteoporosis. 2 0 1
1958 20393940 Family therapy for anorexia nervosa. 1 0 1
1948 12076442 Ribavirin with or without alpha interferon for chronic hepatitis C. 2 0 1
1935 30521693 Pharmacological interventions for acute hepatitis C infection. 5 0 1
1934 28321877 Pharmacological interventions for acute hepatitis B infection: an attempted network meta-analysis. 9 0 1
1933 19821406 Pentoxifylline for alcoholic hepatitis. 3 0 1
1905 24610769 Gloves, extra gloves or special types of gloves for preventing percutaneous exposure injuries in healthcare personnel. 3 0 1
1906 30964545 Glucocorticosteroids for people with alcoholic hepatitis. 4 0 1
1907 15106184 Glucocorticosteroids for viral hepatitis C. 3 0 1
1908 21735424 Hepatic late adverse effects after antineoplastic treatment for childhood cancer. 2 0 1
1911 18677780 Hepatitis B immunisation in persons not previously exposed to hepatitis B or with unknown exposure status. 2 0 1
1915 25300375 Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection. 2 0 1
2241 23801549 Single dose oral ibuprofen plus oxycodone for acute postoperative pain in adults. 1 0 1
2242 23794268 Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. 1 0 1
2243 27654994 Single fixed-dose oral dexketoprofen plus tramadol for acute postoperative pain in adults. 2 0 1
2244 24865446 Sumatriptan (all routes of administration) for acute migraine attacks in adults - overview of Cochrane reviews. 1 0 1
2214 30938843 Herbal medicinal products or preparations for neuropathic pain. 3 0 1
2216 20614434 Interventions for treating brain arteriovenous malformations in adults. 2 0 1
2217 28409830 Magnesium for treating sickle cell disease. 3 0 1
2234 11687054 Rizatriptan for acute migraine. 1 0 1
2220 26263042 Methotrexate for maintenance of remission in ulcerative colitis. 8 0 1
2222 15266458 Non-invasive physical treatments for chronic/recurrent headache. 2 0 1
2223 26544675 Non-prescription (OTC) oral analgesics for acute pain - an overview of Cochrane reviews. 1 0 1
2224 18646121 Normobaric and hyperbaric oxygen therapy for migraine and cluster headache. 2 0 1
2226 12917936 Oral sumatriptan for acute migraine. 1 0 1
2228 26093662 Pharmacological agents for the prevention of vestibular migraine. 1 0 1
2229 18254013 Pharmacological interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood. 4 0 1
2230 11869650 Pharmacological interventions for recurrent abdominal pain (RAP) in childhood. 2 0 1
2231 15106196 Propranolol for migraine prophylaxis. 1 0 1
2232 30270423 Psychological therapies for the management of chronic and recurrent pain in children and adolescents. 7 0 1
2221 24142263 Naproxen with or without an antiemetic for acute migraine headaches in adults. 1 0 1
2260 29509957 Alpha-2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery. 1 0 1
2261 30592787 Alpha-glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased risk of developing type 2 diabetes mellitus. 4 0 1
2262 21154374 Altered dietary salt intake for preventing and treating diabetic kidney disease. 2 0 1
2291 26938118 Different dosage schedules for reducing cardiotoxicity in people with cancer receiving anthracycline chemotherapy. 2 0 1
2213 23797675 Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults. 1 0 1
2212 25892430 Feverfew for preventing migraine. 1 0 1
2211 11687056 Eletriptan for acute migraine. 1 0 1
2254 30941745 Transcutaneous electrical nerve stimulation (TENS) for chronic pain - an overview of Cochrane Reviews. 1 0 1
2245 22336867 Sumatriptan (intranasal route of administration) for acute migraine attacks in adults. 1 0 1
2236 25829028 Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) for the prevention of migraine in adults. 1 0 1
2246 22336849 Sumatriptan (oral route of administration) for acute migraine attacks in adults. 1 0 1
2248 22336869 Sumatriptan (subcutaneous route of administration) for acute migraine attacks in adults. 1 0 1
2249 24142431 Sumatriptan plus naproxen for acute migraine attacks in adults. 1 0 1
2250 25267911 Sumatriptan plus naproxen for acute migraine headaches in adults. 1 0 1
2252 14584010 The effect of vitamin B6 on cognition. 3 0 1
2253 23797676 Topiramate for the prophylaxis of episodic migraine in adults. 1 0 1
2255 18646088 Transcutaneous electrical nerve stimulation (TENS) for chronic pain. 1 0 1
2210 25267910 Eletriptan for acute migraine headaches in adults. 1 0 1
2256 24353996 Triptans for acute cluster headache. 2 0 1
2258 24848613 Zolmitriptan for acute migraine attacks in adults. 1 0 1
2247 22336868 Sumatriptan (rectal route of administration) for acute migraine attacks in adults. 1 0 1
2259 25267904 Zolmitriptan for acute migraine headaches in adults. 1 0 1
2235 16034880 Selective serotonin re-uptake inhibitors (SSRIs) for preventing migraine and tension-type headaches. 1 0 1
2233 25408622 Rizatriptan for acute migraine headaches in adults. 1 0 1
2207 14583952 Drugs for preventing migraine headaches in children. 1 0 1
2209 30110718 E-Health interventions for anxiety and depression in children and adolescents with long-term physical conditions. 2 0 1
2624 24136037 Corticosteroids for viral myocarditis. 1 0 1
2626 11034668 Antibiotics for sore throat. 2 0 1
2641 18843747 Galactomannan detection for invasive aspergillosis in immunocompromized patients. 3 0 1
2363 25400254 Chemotherapy with cetuximab versus chemotherapy alone for chemotherapy-naive advanced non-small cell lung cancer. 6 0 1
2365 11034766 Cranial irradiation for preventing brain metastases of small cell lung cancer in patients in complete remission. 2 0 1
2366 30550641 De-intensified adjuvant (chemo)radiotherapy versus standard adjuvant chemoradiotherapy post transoral minimally invasive surgery for resectable HPV-positive oropharyngeal carcinoma. 3 0 1
2367 25300170 High dose rate versus low dose rate intracavity brachytherapy for locally advanced uterine cervix cancer. 3 0 1
2368 29637538 Hyperbaric oxygenation for tumour sensitisation to radiotherapy. 4 0 1
2359 19588370 Adjuvant platinum-based chemotherapy for early stage cervical cancer. 1 0 1
2369 24474579 Image guided surgery for the resection of brain tumours. 2 0 1
2343 22071813 Public release of performance data in changing the behaviour of healthcare consumers, professionals or organisations. 1 0 1
2341 24963623 Promoting patient uptake and adherence in cardiac rehabilitation. 1 0 1
2319 30537022 Implantable cardiac defibrillators for people with non-ischaemic cardiomyopathy. 2 0 1
2320 24014205 Inspiratory muscle training for asthma. 4 0 1
2321 27749986 Insulin secretagogues for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus. 3 0 1
2322 26343551 Interactive telemedicine: effects on professional practice and health care outcomes. 2 0 1
2323 29953167 Interventions for chronic non-hypovolaemic hypotonic hyponatraemia. 2 0 1
2324 20824881 Interventions for treating peripartum cardiomyopathy to improve outcomes for women and babies. 3 0 1
2326 30706942 Interventions to promote patient utilisation of cardiac rehabilitation. 1 0 1
2327 26694949 Iron therapy for pre-operative anaemia. 2 0 1
2328 27552363 Medical interventions for treating anthracycline-induced symptomatic and asymptomatic cardiotoxicity during and after treatment for childhood cancer. 2 0 1
2342 15674906 Psychological interventions for depression in heart failure. 1 0 1
2329 19821316 Methyldopa for primary hypertension. 3 0 1
2364 25908299 Corticosteroids for the management of cancer-related pain in adults. 2 0 1
2362 20238327 Chemotherapy for advanced gastric cancer. 1 0 1
2504 14583929 Heparins and mechanical methods for thromboprophylaxis in colorectal surgery. 1 0 1
2361 12917954 Calcitonin for metastatic bone pain. 1 0 1
2506 28124411 Imaging for the exclusion of pulmonary embolism in pregnancy. 1 0 1
2507 27243372 Interventions for lowering plasma homocysteine levels in dialysis patients. 5 0 1
2508 18254082 Interventions for preventing venous thromboembolism following abdominal aortic surgery. 5 0 1
2426 23641479 Cochrane reviews on neglected diseases: the case of cutaneous leishmaniasis. 2 0 1
2535 23881695 Topical application of tranexamic acid for the reduction of bleeding. 2 0 1
2425 23440831 Red flags to screen for vertebral fracture in patients presenting with low-back pain. 1 0 1
2423 22972054 Interventions for recurrent corneal erosions. 1 0 1
2345 21735439 Reduced dietary salt for the prevention of cardiovascular disease. 1 0 1
2346 22071853 Sargramostim (GM-CSF) for induction of remission in Crohn's disease. 4 0 1
2347 24733159 Shengmai (a traditional Chinese herbal medicine) for heart failure. 1 0 1
2349 26419913 Stem cell treatment for acute myocardial infarction. 2 0 1
2351 20687083 Structured telephone support or telemonitoring programmes for patients with chronic heart failure. 1 0 1
2352 21833931 Telemonitoring for chronic heart failure: not ready for prime time. 1 0 1
2353 25994229 Tong-xin-luo capsule for patients with coronary heart disease after percutaneous coronary intervention. 1 0 1
2354 18843664 Tongxinluo capsule for acute stroke. 3 0 1
2355 25721946 Transmyocardial laser revascularization versus medical therapy for refractory angina. 1 0 1
2344 25897628 Red blood cell transfusion for people undergoing hip fracture surgery. 1 0 1
2357 21563164 Treatment of valvular heart disease during pregnancy for improving maternal and neonatal outcome. 1 0 1
2360 20238360 Angiogenesis-inhibitors for metastatic thyroid cancer. 2 0 1
2331 23922186 Nitrates for acute heart failure syndromes. 1 0 1
2332 18425927 Non-pharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases. 3 0 1
2333 26689943 Nurse-led titration of angiotensin converting enzyme inhibitors, beta-adrenergic blocking agents, and angiotensin receptor blockers for people with heart failure with reduced ejection fraction. 1 0 1
2334 18646110 Oxygen therapy for dyspnoea in adults. 1 0 1
2415 27701747 Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children. 3 0 1
2416 28220472 Renal denervation for resistant hypertension. 4 0 1
2418 26465274 Tonsillectomy or adenotonsillectomy versus non-surgical management for obstructive sleep-disordered breathing in children. 3 0 1
2419 25464111 Long-term proton pump inhibitor (PPI) use and the development of gastric pre-malignant lesions. 7 0 1
2420 16856003 Autologous cartilage implantation for full thickness articular cartilage defects of the knee. 2 0 1
2421 20927732 Autologous chondrocyte implantation for full thickness articular cartilage defects of the knee. 2 0 1
2422 12519540 Heparin, low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following surgery for hip fractures. 4 0 1
2412 26407098 Calcium channel blockers for pulmonary arterial hypertension. 3 0 1
2398 20556767 Meditation therapies for attention-deficit/hyperactivity disorder (ADHD). 1 0 1
2397 10796802 Interventions for pathological gambling. 3 0 1
2396 25230710 Immediate-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults. 2 0 1
2373 23450565 Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer. 1 0 1
2374 21735393 Radioisotopes for metastatic bone pain. 2 0 1
2375 25989478 Rapid COJEC versus standard induction therapies for high-risk neuroblastoma. 3 0 1
2376 25634649 Retinoic acid post consolidation therapy for high-risk neuroblastoma patients treated with autologous hematopoietic stem cell transplantation. 2 0 1
2377 28840597 Retinoic acid postconsolidation therapy for high-risk neuroblastoma patients treated with autologous haematopoietic stem cell transplantation. 2 0 1
2378 19821394 Selective internal radiation therapy for liver metastases from colorectal cancer. 2 0 1
2379 24970683 Sentinel node assessment for diagnosis of groin lymph node involvement in vulval cancer. 1 0 1
2380 16437498 Surgery versus radiosurgery for patients with a solitary brain metastasis from non-small cell lung cancer. 2 0 1
2414 18646145 Intranasal corticosteroids for nasal airway obstruction in children with moderate to severe adenoidal hypertrophy. 2 0 1
2413 28828761 Coblation versus other surgical techniques for tonsillectomy. 2 0 1
2411 24018587 Botulinum toxin for masseter hypertrophy. 2 0 1
2372 26233609 Platinum versus non-platinum chemotherapy regimens for small cell lung cancer. 4 0 1
2335 26816003 Perioperative angiotensin-converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing mortality and morbidity in adults. 1 0 1
2336 29533470 Perioperative beta-blockers for preventing surgery-related mortality and morbidity. 1 0 1
2337 25733495 Personalised care planning for adults with chronic or long-term health conditions. 1 0 1
2338 27388039 Pharmacological interventions for treating heart failure in patients with Chagas cardiomyopathy. 3 0 1
2340 15674893 Phosphodiesterase III inhibitors for heart failure. 1 0 1
2330 27748503 Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease. 3 0 1
2370 15106258 Palliation of metastatic bone pain: single fraction versus multifraction radiotherapy - a systematic review of the randomised trials. 1 0 1
2371 30888060 Palliative interventions for controlling vaginal bleeding in advanced cervical cancer. 3 0 1
2402 22161373 Parent training interventions for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 5 to 18 years. 3 0 1
2401 29159857 Methylphenidate for children and adolescents with autism spectrum disorder. 4 0 1
2403 25419178 Parent training interventions for attention deficit hyperactivity disorder. 1 0 1
2404 29944175 Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders. 3 0 1
2405 22786509 Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents. 1 0 1
2406 27678554 Polyunsaturated fatty acids (PUFAs) for children with specific learning disorders. 1 0 1
2407 22336841 Pycnogenol(®) for the treatment of chronic disorders. 3 0 1
2408 22513958 Pycnogenol® (extract of French maritime pine bark) for the treatment of chronic disorders. 3 0 1
2409 19370667 Risperidone for attention-deficit hyperactivity disorder in people with intellectual disabilities. 2 0 1
2410 22161422 Social skills training for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 5 to 18 years. 1 0 1
2505 29315455 Home versus in-patient treatment for deep vein thrombosis. 3 0 1
2503 19588346 Heparin for the prevention of venous thromboembolism in general medical patients (excluding stroke and myocardial infarction). 4 0 1
2650 26144877 Vaccines for women for preventing neonatal tetanus. 6 0 1
2468 30004571 Parent training interventions for parents with intellectual disability. 2 0 1
2454 24146298 Treatment of vaginal bleeding irregularities induced by progestin only contraceptives. 1 0 1
2452 30566226 Medical and surgical abortion for women living with HIV. 1 0 1
2427 25742878 Honey as a topical treatment for wounds. 3 0 1
2428 19370612 Interventions for American cutaneous and mucocutaneous leishmaniasis. 1 0 1
2430 29578237 Nutritional supplements for patients being treated for active visceral leishmaniasis. 2 0 1
2432 26246011 Vector and reservoir control for preventing leishmaniasis. 3 0 1
2433 29390170 Absorbable versus non-absorbable sutures for skin closure after carpal tunnel decompression surgery. 2 0 1
2434 14974016 Ergonomic and physiotherapeutic interventions for treating upper extremity work related disorders in adults. 1 0 1
2436 22972082 High-flux versus low-flux membranes for end-stage kidney disease. 3 0 1
2438 12535461 Non-surgical treatment (other than steroid injection) for carpal tunnel syndrome. 1 0 1
2439 26884379 Rehabilitation following carpal tunnel release. 2 0 1
2453 25429714 Strategies for improving postpartum contraceptive use: evidence from non-randomized studies. 1 0 1
2440 17943805 Surgical treatment options for carpal tunnel syndrome. 1 0 1
2443 15846690 20 mcg versus >20 mcg estrogen combined oral contraceptives for contraception. 1 0 1
2444 18843653 20 microg versus >20 microg estrogen combined oral contraceptives for contraception. 1 0 1
2445 23904209 20 µg versus >20 µg estrogen combined oral contraceptives for contraception. 1 0 1
2446 16855983 Biphasic versus monophasic oral contraceptives for contraception. 1 0 1
2447 10796473 Bromocriptine for unexplained subfertility in women. 1 0 1
2448 23641480 Combination injectable contraceptives for contraception. 1 0 1
2478 14583989 Anticoagulant and aspirin prophylaxis for preventing thromboembolism after major gynaecological surgery. 1 0 1
2477 15846745 Risperidone versus olanzapine for schizophrenia. 2 0 1
2501 25159027 Haemodilution for acute ischaemic stroke. 2 0 1
2476 17636774 Psychosocial interventions for erectile dysfunction. 1 0 1
6766 27093058 Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff. 1 0 1
2456 28245347 Autologous serum eye drops for dry eye. 3 0 1
2457 24006231 Interventions for the management of dry mouth: non-pharmacological interventions. 1 0 1
2458 22161442 Interventions for the management of dry mouth: topical therapies. 3 0 1
2461 15674949 Recombinant growth hormone therapy for X-linked hypophosphatemia in children. 3 0 1
2462 27826955 Vitamin D supplementation for preventing infections in children under five years of age. 3 0 1
2463 25922863 Early versus late antiepileptic drug withdrawal for people with epilepsy in remission. 4 0 1
2464 25326792 Non-pharmaceutical management of respiratory morbidity in children with severe global developmental delay. 1 0 1
2465 25805060 Non-speech oral motor treatment for children with developmental speech sound disorders. 2 0 1
2466 18843752 Organising health care services for persons with an intellectual disability. 1 0 1
2455 22071807 Triphasic versus monophasic oral contraceptives for contraception. 1 0 1
2467 27065018 Organising healthcare services for persons with an intellectual disability. 1 0 1
2469 20556787 Parent training support for intellectually disabled parents. 1 0 1
2470 26333428 Pharmacological interventions for epilepsy in people with intellectual disabilities. 3 0 1
2471 23633366 Pharmacological interventions for self-injurious behaviour in adults with intellectual disabilities. 1 0 1
2472 26511368 Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in patients with stroke or transient ischaemic attack. 2 0 1
2473 29197071 Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack. 2 0 1
2474 24343728 Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity. 3 0 1
2475 20927745 Finasteride for benign prostatic hyperplasia. 3 0 1
2449 17253481 Cyclophosphamide for multiple sclerosis. 3 0 1
2450 12137636 Education for contraceptive use by women after childbirth. 1 0 1
2451 14583931 Lactational amenorrhea for family planning. 1 0 1
2441 18843618 Surgical versus non-surgical treatment for carpal tunnel syndrome. 1 0 1
2534 23543562 Thromboprophylaxis for trauma patients. 2 0 1
2524 26091835 Primary prophylaxis for venous thromboembolism in patients undergoing cardiac or thoracic surgery. 1 0 1
2511 24966161 Low molecular weight heparin versus unfractionated heparin for perioperative thromboprophylaxis in patients with cancer. 2 0 1
2510 28780771 Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-limb immobilization. 1 0 1
2509 24615288 Low molecular weight heparin for prevention of central venous catheterization-related thrombosis in children. 4 0 1
2484 29856471 Anticoagulation for people with cancer and central venous catheters. 3 0 1
2485 29993117 Anticoagulation for perioperative thromboprophylaxis in people with cancer. 4 0 1
2486 17636845 Anticoagulation for thrombosis prophylaxis in cancer patients with central venous catheters. 3 0 1
2487 25956410 Antifibrinolytic drugs for acute traumatic injury. 2 0 1
2489 27600864 Combined intermittent pneumatic leg compression and pharmacological prophylaxis for prevention of venous thromboembolism. 2 0 1
2490 24590565 Combined oral contraceptives: venous thrombosis. 2 0 1
2491 27624857 Compression stockings for preventing deep vein thrombosis in airline passengers. 3 0 1
2492 25069620 Continuous passive motion for preventing venous thromboembolism after total knee arthroplasty. 1 0 1
2493 27494075 D-dimer test for excluding the diagnosis of pulmonary embolism. 1 0 1
2494 25528992 Different types of intermittent pneumatic compression devices for preventing venous thromboembolism in patients after total hip replacement. 2 0 1
2495 25749503 Effect of testing for cancer on cancer- and venous thromboembolism (VTE)-related mortality and morbidity in patients with unprovoked VTE. 3 0 1
2496 28832905 Effect of testing for cancer on cancer- and venous thromboembolism (VTE)-related mortality and morbidity in people with unprovoked VTE. 3 0 1
2497 30407621 Effect of testing for cancer on cancer- or venous thromboembolism (VTE)-related mortality and morbidity in people with unprovoked VTE. 3 0 1
2499 10796593 Fixed dose subcutaneous low molecular weight heparins versus adjusted dose unfractionated heparin for venous thromboembolism. 1 0 1
2533 26222250 Surgical versus nonsurgical interventions for flail chest. 4 0 1
2532 19370590 Surgery for obesity. 2 0 1
2531 28195640 Subcutaneous unfractionated heparin for the initial treatment of venous thromboembolism. 2 0 1
2518 30839095 Outpatient versus inpatient treatment for acute pulmonary embolism. 1 0 1
2480 27027384 Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or hip fracture repair. 2 0 1
2481 25764172 Anticoagulants for acute ischaemic stroke. 3 0 1
2482 12519565 Anticoagulation for cerebral sinus thrombosis. 3 0 1
2513 29161465 Neuromuscular electrical stimulation for the prevention of venous thromboembolism. 2 0 1
2514 27898998 Nutritional supplementation for hip fracture aftercare in older people. 2 0 1
2515 17443622 Oral anticoagulation for prolonging survival in patients with cancer. 2 0 1
2516 29285754 Oral anticoagulation in people with cancer who have no therapeutic or prophylactic indication for anticoagulation. 3 0 1
2517 26636644 Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of pulmonary embolism. 2 0 1
2519 17636846 Parenteral anticoagulation for prolonging survival in patients with cancer who have no other indication for anticoagulation. 2 0 1
2530 30707445 Subacromial decompression surgery for rotator cuff disease. 3 0 1
2521 27797404 Pentasaccharides for the prevention of venous thromboembolism. 3 0 1
2522 20687069 Physical methods for preventing deep vein thrombosis in stroke. 4 0 1
2512 28374884 Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke. 3 0 1
2523 22336844 Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy. 1 0 1
2525 30916777 Prolonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery. 1 0 1
2526 28005272 Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy. 6 0 1
2527 24519568 Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period. 1 0 1
2529 16856092 Strontium ranelate for preventing and treating postmenopausal osteoporosis. 1 0 1
2381 30125049 Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis. 1 0 1
2382 21491399 Surgical management for upper urinary tract transitional cell carcinoma. 3 0 1
2383 15674905 Surgical resection and whole brain radiation therapy versus whole brain radiation therapy alone for single brain metastases. 1 0 1
2573 26058964 Vitamin K for upper gastrointestinal bleeding in people with acute or chronic liver diseases. 2 0 1
2575 26041152 Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease. 3 0 1
2576 26408070 Antibiotics for preventing lower respiratory tract infections in high-risk children aged 12 years and under. 3 0 1
2577 23076916 Antibiotics for treating community acquired pneumonia in people with sickle cell disease. 3 0 1
2578 27841444 Antibiotics for treating community-acquired pneumonia in people with sickle cell disease. 4 0 1
2579 27841931 Antibiotics for treating osteomyelitis in people with sickle cell disease. 3 0 1
2580 28094851 Blood transfusion for preventing primary and secondary stroke in people with sickle cell disease. 6 0 1
2571 22972075 Vitamin K for upper gastrointestinal bleeding in patients with acute or chronic liver diseases. 2 0 1
2581 11869654 Blood transfusion for preventing stroke in people with sickle cell disease. 2 0 1
2583 24893174 Deferasirox for managing transfusional iron overload in people with sickle cell disease. 3 0 1
2584 30338520 Drugs for preventing red blood cell dehydration in people with sickle cell disease. 2 0 1
2585 28759112 Fluid replacement therapy for acute episodes of pain in people with sickle cell disease. 2 0 1
2588 19160312 Hematopoietic stem cell transplantation for children with sickle cell disease. 1 0 1
2589 27194464 Hematopoietic stem cell transplantation for people with sickle cell disease. 2 0 1
2590 28426137 Hydroxyurea (hydroxycarbamide) for sickle cell disease. 4 0 1
2591 11406036 Hydroxyurea for sickle cell disease. 1 0 1
2592 28672087 Interventions for chronic kidney disease in people with sickle cell disease. 8 0 1
2593 27711980 Interventions for patients and caregivers to improve knowledge of sickle cell disease and recognition of its related complications. 2 0 1
2582 30125338 Conjugate Haemophilus influenzae type b vaccines for sickle cell disease. 2 0 1
2594 28500860 Interventions for preventing silent cerebral infarcts in people with sickle cell disease. 5 0 1
2574 22696373 Topical microbicides for prevention of sexually transmitted infections. 5 0 1
2572 18677778 Vitamin K for upper gastrointestinal bleeding in patients with liver diseases. 2 0 1
2384 28945270 Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases. 1 0 1
2654 23450543 Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients. 2 0 1
2725 26833493 Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old. 2 0 1
2726 24186774 Continuous negative extrathoracic pressure or continuous positive airway pressure compared to conventional ventilation for acute hypoxaemic respiratory failure in children. 2 0 1
2727 18254028 Continuous negative extrathoracic pressure or continuous positive airway pressure for acute hypoxemic respiratory failure in children. 2 0 1
2728 21678340 Epinephrine for bronchiolitis. 1 0 1
2729 23733383 Glucocorticoids for acute viral bronchiolitis in infants and young children. 1 0 1
2730 24318607 Heliox for croup in children. 1 0 1
2731 26384333 Heliox inhalation therapy for bronchiolitis in infants. 2 0 1
2732 24442856 High-flow nasal cannula therapy for infants with bronchiolitis. 2 0 1
2733 24604698 High-flow nasal cannula therapy for respiratory support in children. 1 0 1
2734 17054220 Immunoglobulin treatment for respiratory syncytial virus infection. 2 0 1
2735 17253528 Inhaled corticosteroids during acute bronchiolitis in the prevention of post-bronchiolitic wheezing. 1 0 1
2736 23450591 Inhaled corticosteroids for subacute cough in children. 1 0 1
2737 25331331 Interventions for managing asthma in pregnancy. 3 0 1
2738 25773054 Leukotriene inhibitors for bronchiolitis in infants and young children. 1 0 1
2739 23152257 Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months. 3 0 1
2741 18843717 Nebulized hypertonic saline solution for acute bronchiolitis in infants. 2 0 1
2660 17443559 Topical lidocaine for the treatment of postherpetic neuralgia. 1 0 1
2537 22258969 Tranexamic acid for upper gastrointestinal bleeding. 2 0 1
2657 21249671 Carbamazepine for acute and chronic pain in adults. 1 0 1
2570 28350426 Pharmacological interventions for primary biliary cholangitis: an attempted network meta-analysis. 5 0 1
2568 26058965 Antifibrinolytic amino acids for upper gastrointestinal bleeding in people with acute or chronic liver disease. 2 0 1
2539 28431186 Unfractionated heparin versus low molecular weight heparins for avoiding heparin-induced thrombocytopenia in postoperative patients. 5 0 1
2541 23076894 Vitamin K antagonists or low-molecular-weight heparin for the long term treatment of symptomatic venous thromboembolism. 2 0 1
2628 22419300 Chinese medicinal herbs for sore throat. 2 0 1
2629 24022333 Oral rinses, mouthwashes and sprays for improving recovery following tonsillectomy. 1 0 1
2630 19160201 Tonsillectomy or adeno-tonsillectomy versus non-surgical treatment for chronic/recurrent acute tonsillitis. 2 0 1
2632 10796824 Tonsillectomy versus non-surgical treatment for chronic / recurrent acute tonsillitis. 1 0 1
2633 16856014 Quinolones for uncomplicated acute cystitis in women. 2 0 1
2634 21328261 Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and palate. 1 0 1
2635 25803231 Treatment for IgG and IgA paraproteinaemic neuropathy. 4 0 1
2637 16856015 Diuretics for Ménière's disease or syndrome. 1 0 1
2639 23744349 Interventions for the restorative care of amelogenesis imperfecta in children and adolescents. 1 0 1
2627 10796842 Antistreptococcal interventions for guttate and chronic plaque psoriasis. 1 0 1
2640 26716951 Galactomannan detection for invasive aspergillosis in immunocompromised patients. 3 0 1
2642 28944952 Bypassing agent prophylaxis in people with hemophilia A or B with inhibitors. 3 0 1
2643 21901684 Clotting factor concentrates given to prevent bleeding and bleeding-related complications in people with hemophilia A or B. 3 0 1
2644 27992070 Exercise for haemophilia. 3 0 1
2645 25165992 Interventions for treating acute bleeding episodes in people with acquired hemophilia A. 2 0 1
2646 27387850 Rituximab for eradicating inhibitors in people with acquired haemophilia A. 2 0 1
2647 28685500 Rituximab for treating inhibitors in people with inherited severe hemophilia. 2 0 1
2648 21735423 Interventions for improving coverage of child immunization in low- and middle-income countries. 3 0 1
2649 27394698 Interventions for improving coverage of childhood immunisation in low- and middle-income countries. 4 0 1
2597 19160301 Interventions for treating painful sickle cell crisis during pregnancy. 1 0 1
2596 25485858 Interventions for treating leg ulcers in people with sickle cell disease. 1 0 1
2595 28759700 Interventions for treating intrahepatic cholestasis in people with sickle cell disease. 4 0 1
2551 18425946 Maintenance agonist treatments for opiate dependent pregnant women. 2 0 1
2542 26822633 Warfarin initiation nomograms for venous thromboembolism. 1 0 1
2543 27075622 Antihelminthics in helminth-endemic areas: effects on HIV disease progression. 5 0 1
2544 25758180 Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas. 2 0 1
2546 10796476 Interventions for treating schistosomiasis haematobium. 3 0 1
2547 10796552 Interventions for treating schistosomiasis mansoni. 2 0 1
2548 30073663 Surgical portosystemic shunts versus devascularisation procedures for prevention of variceal rebleeding in people with hepatosplenic schistosomiasis. 2 0 1
2549 18254104 Treatment of helminth co-infection in HIV-1 infected individuals in resource-limited settings. 1 0 1
2569 15846629 Colchicine for alcoholic and non-alcoholic liver fibrosis and cirrhosis. 2 0 1
2553 30828791 Interventions for infantile seborrhoeic dermatitis (including cradle cap). 3 0 1
2552 24366859 Maintenance agonist treatments for opiate-dependent pregnant women. 3 0 1
2554 24838779 Topical anti-inflammatory agents for seborrhoeic dermatitis of the face or scalp. 2 0 1
2556 12917934 Corticosteroids for idiopathic pulmonary fibrosis. 4 0 1
2557 12137662 Nebulised morphine for severe interstitial lung disease. 8 0 1
2561 29127772 Interventions for treating collagenous colitis. 3 0 1
2563 28540977 Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing assisted reproductive techniques. 4 0 1
2565 25502626 Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility. 2 0 1
2566 17253575 Antifibrinolytic amino acids for acquired coagulation disorders in patients with liver disease. 2 0 1
2567 22972089 Antifibrinolytic amino acids for upper gastrointestinal bleeding in patients with acute or chronic liver disease. 2 0 1
2724 24937099 Bronchodilators for bronchiolitis. 1 0 1
2723 16034861 Anticholinergic drugs for wheeze in children under the age of two years. 1 0 1
2722 24282128 Antibody induction therapy for lung transplant recipients. 2 0 1
2672 27731501 Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS). 1 0 1
2691 19370647 Recruitment manoeuvres for adults with acute lung injury receiving mechanical ventilation. 1 0 1
2703 19821400 Levonorgestrel intrauterine system for endometrial protection in women with breast cancer on adjuvant tamoxifen. 1 0 1
2705 27021481 Non-surgical versus surgical treatment for oesophageal cancer. 5 0 1
2706 23728671 Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach, gastroesophageal junction, and lower esophagus. 1 0 1
2707 25393718 PET-CT for assessing mediastinal lymph node involvement in patients with suspected resectable non-small cell lung cancer. 4 0 1
2708 20091590 Primary surgery versus primary radiation therapy with or without chemotherapy for early adenocarcinoma of the uterine cervix. 4 0 1
2710 29740819 Prophylactic vaccination against human papillomaviruses to prevent cervical cancer and its precursors. 4 0 1
2711 18425932 Resection versus no intervention or other surgical interventions for colorectal cancer liver metastases. 2 0 1
2712 23235651 Screening for oesophageal cancer. 3 0 1
2713 17943820 Second or third additional chemotherapy drug for non-small cell lung cancer in patients with advanced disease. 5 0 1
2714 12535492 Short versus long duration infusions of paclitaxel for any adenocarcinoma. 2 0 1
2704 27432490 Molecular-targeted first-line therapy for advanced gastric cancer. 2 0 1
2715 21563139 Short versus long duration infusions of paclitaxel for any advanced adenocarcinoma. 3 0 1
2690 26561745 Prone position for acute respiratory failure in adults. 2 0 1
2688 27169365 Lateral positioning for critically ill adult patients. 2 0 1
2661 21412911 Vaccination for preventing postherpetic neuralgia. 1 0 1
2665 24515610 Antibiotics for acute maxillary sinusitis in adults. 1 0 1
2666 18425861 Antibiotics for acute maxillary sinusitis. 1 0 1
2668 12519551 Antibiotics for persistent nasal discharge (rhinosinusitis) in children. 2 0 1
2701 27030301 Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer. 5 0 1
2700 17054246 Laparoscopic versus open total mesorectal excision for rectal cancer. 1 0 1
2699 26198377 Helicobacter pylori eradication for the prevention of gastric neoplasia. 2 0 1
2395 17943868 Homeopathy for attention deficit/hyperactivity disorder or hyperkinetic disorder. 2 0 1
2385 16856022 Whole brain radiotherapy for the treatment of multiple brain metastases. 1 0 1
2386 22513917 Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases. 1 0 1
2387 21491402 Acupuncture for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents. 1 0 1
2388 19160313 Amfetamine for attention deficit hyperactivity disorder in people with intellectual disabilities. 4 0 1
2390 26844979 Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents. 2 0 1
2391 22972123 Atypical antipsychotics for disruptive behaviour disorders in children and youths. 4 0 1
2392 28965364 Bupropion for attention deficit hyperactivity disorder (ADHD) in adults. 2 0 1
2393 29566425 Cognitive-behavioural interventions for attention deficit hyperactivity disorder (ADHD) in adults. 1 0 1
2424 27457359 Patching for corneal abrasion. 1 0 1
2698 26267122 Extent of lymph node dissection for adenocarcinoma of the stomach. 2 0 1
2318 24297433 Immunosuppressive T-cell antibody induction for heart transplant recipients. 1 0 1
2536 23440847 Tranexamic acid for reducing mortality in emergency and urgent surgery. 2 0 1
2538 22972111 Unfractionated heparin versus low molecular weight heparin for avoiding heparin-induced thrombocytopenia in postoperative patients. 4 0 1
2692 15106222 Ventilation with lower tidal volumes versus traditional tidal volumes in adults for acute lung injury and acute respiratory distress syndrome. 1 0 1
2693 25470408 Adjuvant chemotherapy after concurrent chemoradiation for locally advanced cervical cancer. 5 0 1
2694 17636789 Adjuvant chemotherapy for small intestine adenocarcinoma. 2 0 1
2696 28796882 Cytology versus HPV testing for cervical cancer screening in the general population. 3 0 1
2697 15495024 Extended versus limited lymph nodes dissection technique for adenocarcinoma of the stomach. 1 0 1
2671 29750825 Cyclamen europaeum extract for acute sinusitis. 1 0 1
2673 21735433 Functional endoscopic balloon dilation of sinus ostia for chronic rhinosinusitis. 1 0 1
2721 28828759 Antibiotics for persistent cough or wheeze following acute bronchiolitis in children. 2 0 1
2674 16856048 Functional endoscopic sinus surgery for chronic rhinosinusitis. 2 0 1
2752 25758322 HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypass. 1 0 1
2753 23881659 Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function. 2 0 1
2754 27699760 Intensity of continuous renal replacement therapy for acute kidney injury. 1 0 1
2745 19821351 Atrial natriuretic peptide for preventing and treating acute kidney injury. 1 0 1
2755 29851032 Interventions for necrotizing soft tissue infections in adults. 4 0 1
2758 28258686 Ischaemic preconditioning for the reduction of renal ischaemia reperfusion injury. 1 0 1
2759 22895948 Nutritional support for acute kidney injury. 1 0 1
2760 29199769 Peritoneal dialysis for acute kidney injury. 1 0 1
2761 22696382 Sodium bicarbonate supplements for treating acute kidney injury. 1 0 1
2762 20556772 Teicoplanin versus vancomycin for proven or suspected infection. 1 0 1
2763 23440810 Thyroid hormones for acute kidney injury. 3 0 1
2764 22696364 Tidal versus other forms of peritoneal dialysis for acute kidney injury. 1 0 1
2765 30560582 Timing of renal replacement therapy initiation for acute kidney injury. 1 0 1
2766 20091556 Acupuncture for depression. 1 0 1
2756 24027097 Interventions for protecting renal function in the perioperative period. 1 0 1
2744 26595825 Amphotericin B deoxycholate versus liposomal amphotericin B: effects on kidney function. 1 0 1
2743 26299681 Surfactant therapy for bronchiolitis in critically ill infants. 2 0 1
2742 21249676 Steam inhalation or humidified oxygen for acute bronchiolitis in children up to three years of age. 1 0 1
2720 21678346 Antibiotics for bronchiolitis in children. 3 0 1
2751 23440825 High-volume haemofiltration for sepsis. 2 0 1
2750 28141912 High-volume haemofiltration for sepsis in adults. 2 0 1
2749 30488949 Effects of peri-operative nonsteroidal anti-inflammatory drugs on post-operative kidney function for adults with normal kidney function. 2 0 1
2684 26593456 Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis. 7 0 1
2676 27115217 Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis. 3 0 1
2689 15495113 Pharmacologic therapies for adults with acute lung injury and acute respiratory distress syndrome. 1 0 1
2677 23922214 Laquinimod for multiple sclerosis. 5 0 1
2679 24310855 Rituximab for relapsing-remitting multiple sclerosis. 3 0 1
2680 20238351 Saline nasal irrigation for acute upper respiratory tract infections. 1 0 1
2681 17443574 Steroids for acute sinusitis. 1 0 1
2682 24664368 Systemic corticosteroids for acute sinusitis. 1 0 1
2683 21833965 Topical and systemic antifungal therapy for the symptomatic treatment of chronic rhinosinusitis. 2 0 1
2685 19160284 Chinese herbal medicine for premenstrual syndrome. 1 0 1
2748 24929959 Continuous renal replacement therapy (CRRT) for rhabdomyolysis. 1 0 1
2686 20614430 Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) and acute lung injury in children and adults. 2 0 1
2687 19160304 Interventions for preventing critical illness polyneuropathy and critical illness myopathy. 1 0 1
2678 25997528 Percutaneous endoscopic gastrostomy versus nasogastric tube feeding for adults with swallowing disturbances. 2 0 1
2716 24062262 Surveillance of gastric intestinal metaplasia for the prevention of gastric cancer. 3 0 1
2717 20091557 Treatment for Barrett's oesophagus. 2 0 1
2718 10796630 Anti-cholinergic drugs for wheeze in children under the age of two years. 1 0 1
2746 24992903 Bicarbonate versus lactate solutions for acute peritoneal dialysis. 1 0 1
2747 25740673 Bicarbonate- versus lactate-buffered solutions for acute continuous haemodiafiltration or haemofiltration. 1 0 1
2113 22419315 One-to-one dietary interventions undertaken in a dental setting to change dietary behaviour. 1 0 1
2114 30380139 One-to-one oral hygiene advice provided in a dental setting for oral health. 2 0 1
2141 11869665 Early versus deferred androgen suppression in the treatment of advanced prostatic cancer. 1 0 1
2901 16856096 Management of toxoplasmic encephalitis in HIV-infected adults (with an emphasis on resource-poor settings). 3 0 1
2906 11034711 Antibiotics for preventing leptospirosis. 1 0 1
2907 10796767 Antibiotics for treating leptospirosis. 2 0 1
2908 15494992 Anticoagulants versus antiplatelet therapy for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attack. 3 0 1
2909 12804399 Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage. 1 0 1
2910 12917893 Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery. 1 0 1
2911 17636753 Arginine supplementation for prevention of necrotising enterocolitis in preterm infants. 1 0 1
2912 21249702 Botulinum toxin injections for low-back pain and sciatica. 1 0 1
2900 23866317 Routine surgery in addition to chemotherapy for treating spinal tuberculosis. 2 0 1
2939 24085634 Flexible sigmoidoscopy versus faecal occult blood testing for colorectal cancer screening in asymptomatic individuals. 1 0 1
2940 19588444 Fluoropyrimidine-HAI (hepatic arterial infusion) versus systemic chemotherapy (SCT) for unresectable liver metastases from colorectal cancer. 1 0 1
2942 27760282 Heated insufflation with or without humidification for laparoscopic abdominal surgery. 3 0 1
2969 19370656 Second-line chemotherapy in advanced and metastatic CRC. 1 0 1
2970 28128439 Second-line systemic therapy for metastatic colorectal cancer. 2 0 1
2971 22258964 Single layer versus double layer suture anastomosis of the gastrointestinal tract. 2 0 1
2972 22336786 Stapled versus handsewn methods for colorectal anastomosis surgery. 2 0 1
2973 21901690 Stapled versus handsewn methods for ileocolic anastomoses. 3 0 1
2976 23821339 Surgery for faecal incontinence in adults. 2 0 1
2977 30480771 Survival differences with immediate versus delayed chemotherapy for asymptomatic incurable metastatic colorectal cancer. 3 0 1
2978 18254064 Systemic prokinetic pharmacologic treatment for postoperative adynamic ileus following abdominal surgery in adults. 3 0 1
2903 10796268 Treatments for toxoplasmosis in pregnancy. 2 0 1
2899 17054237 Operative versus non-operative treatment for thoracolumbar burst fractures without neurological deficit. 1 0 1
2930 19588372 Anti-angiogenic therapies for metastatic colorectal cancer. 1 0 1
2914 27490003 Drug-eluting balloon angioplasty versus uncoated balloon angioplasty for peripheral arterial disease of the lower limbs. 5 0 1
2932 26661580 Blood CEA levels for detecting recurrent colorectal cancer. 2 0 1
2933 15674951 Chinese medical herbs for chemotherapy side effects in colorectal cancer patients. 1 0 1
2934 27056645 Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum. 2 0 1
2935 22071835 Colorectal stents for the management of malignant colonic obstructions. 1 0 1
2936 19588384 Concomitant hyperthermia and radiation therapy for treating locally advanced rectal cancer. 1 0 1
2937 20091614 Duration of adjuvant chemotherapy for patients with non-metastatic colorectal cancer. 1 0 1
2928 17054174 Lithium versus antidepressants in the long-term treatment of unipolar affective disorder. 1 0 1
2938 21563161 Energy source instruments for laparoscopic colectomy. 1 0 1
2915 16856061 Early invasive versus conservative strategies for unstable angina & non-ST-elevation myocardial infarction in the stent era. 3 0 1
2913 14974068 Donepezil for vascular cognitive impairment. 4 0 1
2890 30289565 Interventionist versus expectant care for severe pre-eclampsia between 24 and 34 weeks' gestation. 5 0 1
2891 18646089 Interventions for renal vasculitis in adults. 2 0 1
2892 10796832 Low protein diets delay end-stage renal disease in non diabetic adults with chronic renal failure. 1 0 1
2893 19588328 Low protein diets for chronic kidney disease in non diabetic adults. 3 0 1
2894 11406017 Low protein diets for chronic renal failure in non diabetic adults. 1 0 1
2895 17943784 Modes of administration of antibiotics for symptomatic severe urinary tract infections. 1 0 1
2896 28770975 Paracetamol (acetaminophen) for chronic non-cancer pain in children and adolescents. 2 0 1
2897 22071826 Prostaglandins for adult liver transplanted patients. 1 0 1
2898 24510598 Red cell transfusion management for patients undergoing cardiac surgery for congenital heart disease. 2 0 1
2979 20927750 Traditional Chinese Medicine herbs for stopping bleeding from haemorrhoids. 1 0 1
2968 17253456 Screening for colorectal cancer using the faecal occult blood test, Hemoccult. 1 0 1
2980 21328306 Transparent Cap Colonoscopy versus Standard Colonoscopy for Investigation of Gastrointestinal Tract Conditions. 2 0 1
2982 22419309 Workload and surgeon's specialty for outcome after colorectal cancer surgery. 1 0 1
2954 18425886 Long-term results of laparoscopic colorectal cancer resection. 2 0 1
2955 15674882 Mechanical bowel preparation for elective colorectal surgery. 1 0 1
2956 30209805 Mesh versus non-mesh for inguinal and femoral hernia repair. 3 0 1
2957 24122576 Microwave coagulation for liver metastases. 4 0 1
2958 22895981 Non-resection versus resection for an asymptomatic primary tumour in patients with unresectable stage IV colorectal cancer. 1 0 1
2959 28752564 Oral versus intravenous fluoropyrimidines for colorectal cancer. 6 0 1
2960 10796809 Palliative chemotherapy for advanced or metastatic colorectal cancer. Colorectal Meta-analysis Collaboration. 1 0 1
2961 16437512 Perioperative blood transfusions for the recurrence of colorectal cancer. 1 0 1
2962 23450534 Personalised risk communication for informed decision making about taking screening tests. 1 0 1
2963 22419291 Postoperative adjuvant chemotherapy in rectal cancer operated for cure. 2 0 1
2964 19160325 Pre and peri-operative erythropoietin for reducing allogeneic blood transfusions in colorectal cancer surgery. 1 0 1
2889 12137674 Interventionist versus expectant care for severe pre-eclampsia before term. 3 0 1
2993 16856040 Disposable nappies for preventing napkin dermatitis in infants. 1 0 1
2888 28594069 Glucose targets for preventing diabetic kidney disease and its progression. 4 0 1
2886 10796261 Drugs for rapid treatment of very high blood pressure during pregnancy. 3 0 1
2810 10796720 Interventions for chronic suppurative otitis media. 1 0 1
2811 23633358 Interventions for the prevention of postoperative ear discharge after insertion of ventilation tubes (grommets) in children. 1 0 1
2812 16235325 Interventions to improve antibiotic prescribing practices in ambulatory care. 2 0 1
2813 22513907 Neuraminidase inhibitors for preventing and treating influenza in children (published trials only). 2 0 1
2953 24265176 Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation. 3 0 1
2952 24737031 Laparoscopic versus open total mesorectal excision for rectal cancer. 2 0 1
2951 21249684 Laparoscopic versus Open surgery for small bowel Crohn's disease. 3 0 1
2981 23235654 Transparent cap colonoscopy versus standard colonoscopy to improve caecal intubation. 2 0 1
2983 11406045 A comparison of speech and language therapy techniques for dysarthria in Parkinson's disease. 2 0 1
2984 18646143 Intervention for dysarthria associated with acquired brain injury in children and adolescents. 1 0 1
2985 29845607 Interventions for childhood apraxia of speech. 2 0 1
2986 28121021 Interventions for dysarthria due to stroke and other adult-acquired, non-progressive brain injury. 3 0 1
2987 16034872 Speech and language therapy for dysarthria due to non-progressive brain damage. 1 0 1
2988 11406044 Speech and language therapy for dysarthria in Parkinson's disease. 2 0 1
2989 27428115 Speech therapy for children with dysarthria acquired before three years of age. 2 0 1
2991 27007217 Antimicrobial dressings for the prevention of catheter-related infections in newborn infants with central venous catheters. 2 0 1
2967 22696357 Radiofrequency ablation in the treatment of liver metastases from colorectal cancer. 1 0 1
2950 26869023 Irinotecan chemotherapy combined with fluoropyrimidines versus irinotecan alone for overall survival and progression-free survival in patients with advanced and/or metastatic colorectal cancer. 4 0 1
2966 23235607 Quality of life after rectal resection for cancer, with or without permanent colostomy. 1 0 1
2965 15495028 Prophylactic anastomotic drainage for colorectal surgery. 1 0 1
2943 17054184 Hepatic artery adjuvant chemotherapy for patients having resection or ablation of colorectal cancer metastatic to the liver. 1 0 1
2944 22592697 Herbal medicines for advanced colorectal cancer. 1 0 1
2945 22895966 Histamine type 2 receptor antagonists as adjuvant treatment for resected colorectal cancer. 1 0 1
2946 28542712 Histologic scoring indices for evaluation of disease activity in ulcerative colitis. 4 0 1
2947 24065550 Interventions for promoting habitual exercise in people living with and beyond cancer. 1 0 1
2949 19160246 Intra-peritoneal prophylactic agents for preventing adhesions and adhesive intestinal obstruction after non-gynaecological abdominal surgery. 3 0 1
2931 22336793 Antibiotic prophylaxis for hernia repair. 2 0 1
2929 29144545 Music therapy for depression. 1 0 1
3492 25420029 Laser photocoagulation for proliferative diabetic retinopathy. 3 0 1
3460 25914907 Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease. 2 0 1
3462 27575957 Interventions for men and women with their first episode of genital herpes. 4 0 1
3493 25961835 Macular grid laser photocoagulation for branch retinal vein occlusion. 3 0 1
3218 10796690 Ovulation induction with urinary follicle stimulating hormone versus human menopausal gonadotropin for clomiphene-resistant polycystic ovary syndrome. 2 0 1
3495 30320466 Monotherapy laser photocoagulation for diabetic macular oedema. 2 0 1
3497 18425965 Pentoxifylline for diabetic retinopathy. 2 0 1
3524 16034970 Granulocyte transfusions for treating infections in patients with neutropenia or neutrophil dysfunction. 1 0 1
3525 27128488 Granulocyte transfusions for treating infections in people with neutropenia or neutrophil dysfunction. 1 0 1
3527 27755646 Hydroxyurea for reducing blood transfusion in non-transfusion dependent beta thalassaemias. 3 0 1
3528 26544114 Interleukin-2 as maintenance therapy for children and adults with acute myeloid leukaemia in first complete remission. 2 0 1
3529 25860512 Janus kinase-1 and Janus kinase-2 inhibitors for treating myelofibrosis. 6 0 1
3530 27107610 Low bacterial diet versus control diet to prevent infection in cancer patients treated with chemotherapy causing episodes of neutropenia. 2 0 1
3531 24105485 Oral versus intravenous antibiotic treatment for febrile neutropenia in cancer patients. 1 0 1
3532 30168576 Probiotics for the prevention or treatment of chemotherapy- or radiotherapy-related diarrhoea in people with cancer. 2 0 1
3533 24277633 Prophylactic antibiotics for preventing Gram positive infections associated with long-term central venous catheters in oncology patients. 1 0 1
3523 26118415 Granulocyte transfusions for preventing infections in people with neutropenia or neutrophil dysfunction. 1 0 1
3534 19160320 Prophylactic antibiotics or G-CSF for the prevention of infections and improvement of survival in cancer patients undergoing chemotherapy. 1 0 1
3536 23152253 Rituximab, ofatumumab and other monoclonal anti-CD20 antibodies for chronic lymphocytic leukaemia. 2 0 1
3537 25188768 Routine versus selective antifungal administration for control of fungal infections in patients with cancer. 1 0 1
3538 10796426 Thienopyridine derivatives (ticlopidine, clopidogrel) versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients. 4 0 1
3461 26068958 Devices and dressings to secure peripheral venous catheters to prevent complications. 1 0 1
3459 24895299 Aloe vera for prevention and treatment of infusion phlebitis. 1 0 1
2927 25000907 Alternating current cranial electrotherapy stimulation (CES) for depression. 1 0 1
3458 17943744 Vitamin A supplementation to prevent mortality and short and long-term morbidity in very low birthweight infants. 4 0 1
3465 11687138 Tirilazad for acute ischaemic stroke. 2 0 1
3464 28005271 Progesterone for acute traumatic brain injury. 1 0 1
3463 26244380 Intravenous in-line filters for preventing morbidity and mortality in neonates. 1 0 1
3442 11687094 Gradual versus abrupt discontinuation of oxygen in preterm or low birth weight infants. 2 0 1
3443 12804488 Indomethacin for asymptomatic patent ductus arteriosus in preterm infants. 3 0 1
3444 29035425 Inhaled versus systemic corticosteroids for the treatment of bronchopulmonary dysplasia in ventilated very low birth weight preterm infants. 5 0 1
3445 29431872 Interventions to prevent hypothermia at birth in preterm and/or low birth weight infants. 5 0 1
3446 30776084 Late erythropoiesis-stimulating agents to prevent red blood cell transfusion in preterm or low birth weight infants. 2 0 1
3447 24760628 Late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. 2 0 1
3448 21901708 Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity. 2 0 1
3449 27716943 Paracetamol (acetaminophen) for prevention or treatment of pain in newborns. 2 0 1
3450 10796444 Peripheral retinal ablation for threshold retinopathy of prematurity in preterm infants. 2 0 1
3451 17443527 Prolonged versus short course of indomethacin for the treatment of patent ductus arteriosus in preterm infants. 4 0 1
3452 18254095 Prophylactic surgical ligation of patent ductus arteriosus for prevention of mortality and morbidity in extremely low birth weight infants. 5 0 1
3453 19160188 Restricted versus liberal oxygen exposure for preventing morbidity and mortality in preterm or low birth weight infants. 2 0 1
3454 14583967 Selenium supplementation to prevent short-term morbidity in preterm neonates. 2 0 1
3455 23440783 Sucrose for analgesia in newborn infants undergoing painful procedures. 2 0 1
3456 12804470 Supplemental oxygen for the treatment of prethreshold retinopathy of prematurity. 2 0 1
3457 12519545 Vitamin A supplementation for preventing morbidity and mortality in very low birthweight infants. 4 0 1
3540 15106163 Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis. 1 0 1
3541 21328265 Thymic peptides for treatment of cancer patients. 1 0 1
3542 11687144 Ticlopidine versus oral anticoagulation for coronary stenting. 5 0 1
3543 26899263 Very early discharge versus early discharge versus non-early discharge in children with cancer and febrile neutropenia. 2 0 1
3515 20556756 Concurrent chemoradiotherapy in non-small cell lung cancer. 2 0 1
3516 30605229 Early discontinuation of antibiotics for febrile neutropenia versus continuation until neutropenia resolution in people with cancer. 2 0 1
3517 27943261 Efavirenz or nevirapine in three-drug combination therapy with two nucleoside or nucleotide-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals. 2 0 1
3518 12917944 G-CSF and GM-CSF for treating or preventing neonatal infections. 1 0 1
3519 29336009 Gefitinib for advanced non-small cell lung cancer. 3 0 1
3496 25564068 Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy. 2 0 1
1847 16625564 Electromagnetic therapy for treating pressure ulcers. 1 0 1
3217 17636653 Laparoscopic 'drilling' by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. 2 0 1
3214 12917943 Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome. 3 0 1
2917 21249686 Factor Xa inhibitors for acute coronary syndromes. 1 0 1
2918 25097101 Gamma aminobutyric acid (GABA) receptor agonists for acute stroke. 2 0 1
2920 27611108 Immediate versus delayed treatment for recently symptomatic carotid artery stenosis. 3 0 1
2921 16034869 Oral anticoagulants for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks. 3 0 1
2922 12917910 Primary angioplasty versus intravenous thrombolysis for acute myocardial infarction. 2 0 1
2923 29237099 Calcium channel blockers for primary and secondary Raynaud's phenomenon. 4 0 1
2924 23450535 Cyclophosphamide versus methylprednisolone for treating neuropsychiatric involvement in systemic lupus erythematosus. 2 0 1
2925 15106233 Light therapy for non-seasonal depression. 1 0 1
2926 27727432 S-adenosyl methionine (SAMe) for depression in adults. 1 0 1
2916 20238333 Early invasive versus conservative strategies for unstable angina and non-ST elevation myocardial infarction in the stent era. 3 0 1
3514 25356786 Colony-stimulating factors for chemotherapy-induced febrile neutropenia. 1 0 1
3513 16034921 Colony stimulating factors for prevention of myelosupressive therapy induced febrile neutropenia in children with acute lymphoblastic leukaemia. 1 0 1
3512 12917942 Colony stimulating factors for chemotherapy induced febrile neutropenia. 1 0 1
3500 25686158 Topical non-steroidal anti-inflammatory agents for diabetic cystoid macular oedema. 3 0 1
3544 16855999 Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy. 2 0 1
3545 20393938 Surgical management of pelvic organ prolapse in women. 1 0 1
3535 16856041 Purine antagonists for chronic lymphocytic leukaemia. 3 0 1
3522 19160254 Granulocyte transfusions for preventing infections in patients with neutropenia or neutrophil dysfunction. 1 0 1
3521 21975741 Granulocyte transfusions for neonates with confirmed or suspected sepsis and neutropenia. 1 0 1
3520 26880256 Granulocyte and granulocyte-macrophage colony stimulating factors for newly diagnosed patients with myelodysplastic syndromes. 2 0 1
3498 17253568 Postnatal thyroid hormones for preterm infants with transient hypothyroxinaemia. 2 0 1
3499 24214280 Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus. 3 0 1
3501 18254110 Vitamin C and superoxide dismutase (SOD) for diabetic retinopathy. 2 0 1
3511 23949842 Cisplatin versus carboplatin in combination with third-generation drugs for advanced non-small cell lung cancer. 4 0 1
3502 27455388 Dopamine agonists for preventing future miscarriage in women with idiopathic hyperprolactinemia and recurrent miscarriage history. 2 0 1
3503 25188673 Amphotericin B lipid soluble formulations versus amphotericin B in cancer patients with neutropenia. 1 0 1
3504 10908480 Amphotericin B lipid soluble formulations vs amphotericin B in cancer patients with neutropenia. 1 0 1
3505 25188769 Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients. 1 0 1
3506 10908468 Amphotericin B vs fluconazole for controlling fungal infections in neutropenic cancer patients. 1 0 1
3507 21069685 Anti-pseudomonal beta-lactams for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams. 2 0 1
3508 23813455 Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropenia. 1 0 1
3510 25879092 Chemotherapy for children with medulloblastoma. 3 0 1
2814 22258949 Neuraminidase inhibitors for preventing and treating influenza in children. 2 0 1
2817 27977844 Paracetamol (acetaminophen) or non-steroidal anti-inflammatory drugs, alone or combined, for pain relief in acute otitis media in children. 2 0 1
2818 11869626 Pneumococcal vaccine for asthma. 1 0 1
3132 23728656 Acupuncture for glaucoma. 2 0 1
3108 11405956 Interventions for treating acute and chronic Achilles tendinitis. 1 0 1
3109 18254085 Surgery for rotator cuff disease. 4 0 1
3110 19588386 Topical glyceryl trinitrate for rotator cuff disease. 1 0 1
3111 23740534 Treatment of infantile spasms. 2 0 1
3112 19588412 Interventions for erythema nodosum leprosum. 2 0 1
3113 17253535 Antioxidant supplements for non-alcoholic fatty liver disease and/or steatohepatitis. 4 0 1
3114 20091629 Bariatric surgery for non-alcoholic steatohepatitis in obese patients. 5 0 1
3115 17253543 Probiotics for non-alcoholic fatty liver disease and/or steatohepatitis. 4 0 1
3116 30480778 Anti-angiogenic therapy for high-grade glioma. 2 0 1
3131 27526051 Ab interno trabecular bypass surgery with Trabectome for open angle glaucoma. 1 0 1
3117 25242542 Antiangiogenic therapy for high-grade glioma. 2 0 1
3120 18646178 Chemotherapeutic wafers for High Grade Glioma. 1 0 1
3122 21412902 Chemotherapy wafers for high grade glioma. 1 0 1
3123 27541334 External beam radiation dose escalation for high grade glioma. 1 0 1
3124 29355914 Intraoperative imaging technology to maximise extent of resection for glioma. 1 0 1
3125 29357120 Magnetic resonance perfusion for differentiating low-grade from high-grade gliomas at first presentation. 1 0 1
3126 28744879 Procarbazine, lomustine and vincristine for recurrent high-grade glioma. 1 0 1
3127 27378212 Radiotherapy for diffuse brainstem glioma in children and young adults. 2 0 1
3128 23543552 Maternal position during caesarean section for preventing maternal and neonatal complications. 1 0 1
3130 30919929 Ab interno trabecular bypass surgery with iStent for open-angle glaucoma. 1 0 1
3161 23076924 Chemotherapy for metastatic and recurrent cervical cancer. 1 0 1
2819 14973970 Pneumococcal vaccines for preventing otitis media. 1 0 1
3145 29897635 Iridotomy to slow progression of visual field loss in angle-closure glaucoma. 1 0 1
3135 25774087 Combination medical treatment for primary open angle glaucoma and ocular hypertension: a network meta-analysis. 3 0 1
3136 29694684 Cyclodestructive procedures for non-refractory glaucoma. 2 0 1
3137 30852841 Cyclodestructive procedures for refractory glaucoma. 4 0 1
3138 30801132 Endoscopic cyclophotocoagulation (ECP) for open angle glaucoma and primary angle closure. 1 0 1
3139 26599668 Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma. 1 0 1
3140 23633333 Interventions for improving adherence to ocular hypotensive therapy. 2 0 1
3141 22972097 Interventions for late trabeculectomy bleb leak. 1 0 1
3142 28838031 Interventions for the management of CMV-associated anterior segment inflammation. 1 0 1
3133 26769010 Anti-vascular endothelial growth factor for control of wound healing in glaucoma surgery. 2 0 1
3144 27551238 Iridotomy to slow progression of angle-closure glaucoma. 1 0 1
3146 22336823 Laser peripheral iridoplasty for angle-closure. 1 0 1
3147 17943806 Laser trabeculoplasty for open angle glaucoma. 1 0 1
3152 28231380 Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty. 1 0 1
3153 11686977 Post-operative 5-Fluorouracil for glaucoma surgery. 1 0 1
3154 17054274 Screening for prevention of optic nerve damage due to chronic open angle glaucoma. 1 0 1
3155 30554418 Subconjunctival draining minimally-invasive glaucoma devices for medically uncontrolled glaucoma. 2 0 1
3156 25636153 Surgical interventions for primary congenital glaucoma. 2 0 1
3159 19821430 Adjuvant radiotherapy and chemoradiation after surgery for cervical cancer. 1 0 1
3160 28109160 Antibiotics for infection prevention after excision of the cervical transformation zone. 4 0 1
3129 24554410 5-Fluorouracil for glaucoma surgery. 1 0 1
3118 21833969 Antiepileptic drugs for treating seizures in adults with brain tumours. 1 0 1
3162 16034873 Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix. 1 0 1
3163 30362204 Extended-field radiotherapy for locally advanced cervical cancer. 2 0 1
3191 10908485 Azoles for allergic bronchopulmonary aspergillosis. 3 0 1
3190 15266440 Azoles for allergic bronchopulmonary aspergillosis associated with asthma. 4 0 1
3189 27153247 Non-absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic encephalopathy in people with cirrhosis. 6 0 1
3165 25562623 Follow-up strategies after treatment (large loop excision of the transformation zone (LLETZ)) for cervical intraepithelial neoplasia (CIN): Impact of human papillomavirus (HPV) test. 2 0 1
3166 23543559 Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions. 2 0 1
3167 25847525 Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer. 2 0 1
3168 28125861 Immediate referral to colposcopy versus cytological surveillance for minor cervical cytological abnormalities in the absence of HPV test. 1 0 1
3169 21491379 Interventions for encouraging sexual behaviours intended to prevent cervical cancer. 1 0 1
3170 10796735 Interventions for encouraging sexual lifestyles and behaviours intended to prevent cervical cancer. 3 0 1
3171 22161395 Interventions for reducing anxiety in women undergoing colposcopy. 1 0 1
3173 24085528 Laparoscopically assisted radical vaginal hysterectomy versus radical abdominal hysterectomy for the treatment of early cervical cancer. 1 0 1
3174 15106161 Neoadjuvant chemotherapy for locally advanced cervix cancer. 1 0 1
3175 23235641 Neoadjuvant chemotherapy plus surgery versus surgery for cervical cancer. 1 0 1
3176 30746689 Nerve-sparing radical hysterectomy compared to standard radical hysterectomy for women with early stage cervical cancer (stage Ia2 to IIa). 2 0 1
3177 29095502 Obstetric outcomes after conservative treatment for cervical intraepithelial lesions and early invasive disease. 4 0 1
3178 23543561 Pre-treatment surgical para-aortic lymph node assessment in locally advanced cervical cancer. 1 0 1
3179 22592722 Radiotherapy and chemoradiation after surgery for early cervical cancer. 1 0 1
3180 20091664 Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: individual patient data meta-analysis. 2 0 1
3181 16856035 Screening programmes for the early detection and prevention of oral cancer. 1 0 1
3203 22419292 Central venous access sites for the prevention of venous thrombosis, stenosis and infection. 2 0 1
3213 11034687 Gonadotrophin therapy for ovulation induction in subfertility associated with polycystic ovary syndrome. 2 0 1
3211 26107113 Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia. 7 0 1
3200 30004572 Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid antibodies. 6 0 1
3164 24277645 Follow-up protocols for women with cervical cancer after primary treatment. 1 0 1
3193 26424726 Polymerase chain reaction blood tests for the diagnosis of invasive aspergillosis in immunocompromised people. 1 0 1
3194 16437492 Voriconazole versus amphotericin B in cancer patients with neutropenia. 2 0 1
3195 24563222 Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia. 2 0 1
3196 23450583 Prophylactic gastrojejunostomy for unresectable periampullary carcinoma. 3 0 1
3197 20556784 Anticoagulant therapy for deep vein thrombosis (DVT) in pregnancy. 2 0 1
3198 27098266 Antiepileptic drugs for the primary and secondary prevention of seizures after intracranial venous thrombosis. 1 0 1
3199 25695213 Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery. 2 0 1
3201 25271409 Capsule endoscopy for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis. 3 0 1
3210 14974030 Thrombolysis for cerebral vein and dural sinus thrombosis. 1 0 1
3192 29587336 Oral versus inhaled antibiotics for bronchiectasis. 4 0 1
3202 17636746 Central venous access sites for the prevention of venous thrombosis, stenosis and infection in patients requiring long-term intravenous therapy. 2 0 1
3204 18425882 Continuous heparin infusion to prevent thrombosis and catheter occlusion in neonates with peripherally placed percutaneous central venous catheters. 2 0 1
3205 24590623 Different unfractionated heparin doses for preventing arterial thrombosis in children undergoing cardiac catheterization. 3 0 1
3206 20614425 Elastic compression stockings for prevention of deep vein thrombosis. 2 0 1
3207 27820879 Heparin for the treatment of thrombosis in neonates. 6 0 1
3208 22592717 Knee length versus thigh length graduated compression stockings for prevention of deep vein thrombosis in postoperative surgical patients. 2 0 1
3209 29199766 Pentasaccharides for the treatment of deep vein thrombosis. 4 0 1
3134 28750481 Aqueous shunts for glaucoma. 1 0 1
2996 27841440 Interventions for preventing and treating incontinence-associated dermatitis in adults. 1 0 1
2995 11406053 Gold as an oral corticosteroid sparing agent in stable asthma. 2 0 1
2867 16856064 Late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. 5 0 1
2782 11687020 Antibiotics for spontaneous bacterial peritonitis in cirrhotics. 2 0 1
2783 28390069 Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients. 2 0 1
2784 30362116 Biocompatible dialysis fluids for peritoneal dialysis. 1 0 1
2806 17253499 Identification of children in the first four years of life for early treatment for otitis media with effusion. 1 0 1
2785 15495125 Catheter type, placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients. 2 0 1
2787 25117423 Double bag or Y-set versus standard transfer systems for continuous ambulatory peritoneal dialysis in end-stage kidney disease. 2 0 1
2788 11406068 Double bag or Y-set versus standard transfer systems for continuous ambulatory peritoneal dialysis in end-stage renal disease. 1 0 1
2789 26630451 Etrolizumab for induction of remission in ulcerative colitis. 3 0 1
2790 21901677 Mechanical bowel preparation for elective colorectal surgery. 1 0 1
2791 18843708 Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers. 1 0 1
2792 17253565 Primary closure versus T-tube drainage after open common bile duct exploration. 1 0 1
2793 26568111 Surgical versus non-surgical management of abdominal injury. 1 0 1
2794 24771351 Treatment for peritoneal dialysis-associated peritonitis. 1 0 1
2796 15266512 Antibiotic prophylaxis in clean and clean-contaminated ear surgery. 2 0 1
2786 17443624 Continuous ambulatory peritoneal dialysis versus automated peritoneal dialysis for end-stage renal disease. 1 0 1
2837 26421585 Cyclophosphamide versus ifosfamide for paediatric and young adult bone and soft tissue sarcoma patients. 2 0 1
2838 12917960 Doxorubicin-based chemotherapy for the palliative treatment of adult patients with locally advanced or metastatic soft tissue sarcoma. 2 0 1
2839 28654140 Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer. 5 0 1
2865 18254020 Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. 5 0 1
2780 15846719 Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults. 2 0 1
2779 19370611 Antibiotic prophylaxis for spontaneous bacterial peritonitis in cirrhotic patients with ascites, without gastro-intestinal bleeding. 3 0 1
2777 28516471 Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions. 2 0 1
2832 11034717 Adjuvant chemotherapy for localised resectable soft tissue sarcoma in adults. 2 0 1
2820 24955444 Preventing otitis media with pneumococcal conjugate vaccine: more data than certainty? 1 0 1
2809 27854381 Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube) insertion. 1 0 1
2821 12804500 Screening children in the first four years of life to undergo early treatment for otitis media with effusion. 1 0 1
2825 29543327 Systemic corticosteroids for acute otitis media in children. 1 0 1
2826 16856108 Topical analgesia for acute otitis media. 1 0 1
2827 16235370 Topical antibiotics without steroids for chronically discharging ears with underlying eardrum perforations. 2 0 1
2828 11869601 Vitamin A for treating measles in children. 1 0 1
2831 21249664 Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults. 2 0 1
2833 10796873 Adjuvant chemotherapy for localised resectable soft tissue sarcoma in adults. Sarcoma Meta-analysis Collaboration (SMAC). 2 0 1
2776 30566763 Single herbal medicine for diabetic retinopathy. 3 0 1
2834 23450567 Chemotherapy and/or radiotherapy in combination with surgery for ovarian carcinosarcoma. 2 0 1
2835 28290161 Corticosteroids for tuberculous pleurisy. 3 0 1
2822 10796591 Short course antibiotics for acute otitis media. 1 0 1
2836 12917946 Cotrimoxazole prophylaxis for opportunistic infections in adults with HIV. 4 0 1
2808 20091565 Interventions for acute otitis externa. 3 0 1
2803 28881007 Delayed antibiotic prescriptions for respiratory infections. 3 0 1
2773 22419335 Histamine H2-receptor antagonists for urticaria. 2 0 1
2774 23543544 Prebiotics in infants for prevention of allergy. 2 0 1
2866 17636641 Inhaled nitric oxide for respiratory failure in preterm infants. 1 0 1
2868 29726010 Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth. 3 0 1
2994 10796254 Emollient ointment for preventing infection in preterm infants. 1 0 1
2869 25699678 Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants. 1 0 1
2843 25313415 Treatment of severe or progressive Kaposi's sarcoma in HIV-infected adults. 3 0 1
2844 17054286 Bisphosphonates for advanced prostate cancer. 1 0 1
2845 20238320 Bisphosphonates in multiple myeloma. 3 0 1
2846 22592688 Bisphosphonates in multiple myeloma: a network meta-analysis. 3 0 1
2847 29253322 Bisphosphonates in multiple myeloma: an updated network meta-analysis. 3 0 1
2848 27096326 Bortezomib for the treatment of multiple myeloma. 5 0 1
2849 12535504 Early versus deferred treatment for early stage multiple myeloma. 3 0 1
2850 23076906 First-line tandem high-dose chemotherapy and autologous stem cell transplantation versus single high-dose chemotherapy and autologous stem cell transplantation in multiple myeloma, a systematic review of controlled studies. 1 0 1
2851 27906452 Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy. 2 0 1
2852 26630252 Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants. 8 0 1
2853 28869278 Cerebral near-infrared spectroscopy monitoring for prevention of brain injury in very preterm infants. 4 0 1
2854 17054219 Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates. 7 0 1
2855 18843729 Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth. 3 0 1
2856 12917901 Dopamine versus dobutamine for hypotensive preterm infants. 1 0 1
2857 12137683 Dopamine versus no treatment to prevent renal dysfunction in indomethacin-treated preterm newborn infants. 2 0 1
2858 29145693 Early erythropoiesis-stimulating agents in preterm or low birth weight infants. 3 0 1
2859 16856062 Early erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. 5 0 1
2860 22895933 Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes. 2 0 1
2887 29181841 Epidural therapy for the treatment of severe pre-eclampsia in non labouring women. 7 0 1
2842 12917957 Treatment of Kaposi's sarcoma in HIV-1 infected individuals with emphasis on resource poor settings. 2 0 1
2841 24464843 Treatment of Kaposi sarcoma in children with HIV-1 infection. 1 0 1
2840 21154373 High-dose chemotherapy for children and young adults with stage IV rhabdomyosarcoma. 3 0 1
2878 11279743 Superoxide dismutase for preventing chronic lung disease in mechanically ventilated preterm infants. 6 0 1
2870 14584009 Pentoxifylline for neonatal sepsis. 1 0 1
2871 25418278 Pentoxifylline for the prevention of bronchopulmonary dysplasia in preterm infants. 4 0 1
2872 25751631 Pentoxifylline for treatment of sepsis and necrotizing enterocolitis in neonates. 3 0 1
2873 11406029 Permissive hypercapnia for the prevention of morbidity and mortality in mechanically ventilated newborn infants. 1 0 1
2864 12804469 Ibuprofen for the treatment of a patent ductus arteriosus in preterm and/or low birth weight infants. 5 0 1
2874 22513930 Recombinant human activated protein C for severe sepsis in neonates. 1 0 1
2876 27384151 Sealing procedures for preterm prelabour rupture of membranes. 3 0 1
2877 25633155 Sound reduction management in the neonatal intensive care unit for preterm or very low birth weight infants. 5 0 1
2879 12076462 Tracheal gas insufflation for the prevention of morbidity and mortality in mechanically ventilated newborn infants. 3 0 1
2861 28658720 Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants. 1 0 1
2880 23543571 Vasopressin and its analogues for the treatment of refractory hypotension in neonates. 3 0 1
2881 29633784 Optical correction of refractive error for preventing and treating eye symptoms in computer users. 2 0 1
2882 15654703 Screening for correctable visual acuity deficits in school-age children and adolescents. 1 0 1
2883 29446439 Vision screening for correctable visual acuity deficits in school-age children and adolescents. 1 0 1
2885 30073665 Colloids versus crystalloids for fluid resuscitation in critically ill people. 1 0 1
2875 17636741 Repeat doses of prenatal corticosteroids for women at risk of preterm birth for preventing neonatal respiratory disease. 3 0 1
2863 29505664 Higher versus lower amino acid intake in parenteral nutrition for newborn infants. 3 0 1
2862 28727900 Head midline position for preventing the occurrence or extension of germinal matrix-intraventricular hemorrhage in preterm infants. 3 0 1
3479 21563152 Methotrexate for high-grade osteosarcoma in children and young adults. 1 0 1
3491 29333660 Interventions to increase attendance for diabetic retinopathy screening. 2 0 1
2767 23152246 Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents. 2 0 1
3431 26523368 Chest shielding for prevention of a haemodynamically significant patent ductus arteriosus in preterm infants receiving phototherapy. 3 0 1
3433 27508358 Cycled light in the intensive care unit for preterm and low birth weight infants. 2 0 1
3434 24002688 D-Penicillamine for preventing retinopathy of prematurity in preterm infants. 2 0 1
3435 20091516 Early (< 8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. 2 0 1
3436 24771408 Early erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. 2 0 1
3437 23922202 Early light reduction for preventing retinopathy of prematurity in very low birth weight infants. 2 0 1
3428 15266486 Pharmacological and nutritional treatment for McArdle's disease (Glycogen Storage Disease type V). 3 0 1
3413 26417855 Fertility and early pregnancy outcomes after conservative treatment for cervical intraepithelial neoplasia. 1 0 1
3412 12076416 Surgical versus non-surgical treatment for carpal tunnel syndrome. 1 0 1
3411 26486929 Sodium channel blockers for neuroprotection in multiple sclerosis. 4 0 1
1 29308602 Anti-vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity. 5 0 1
3386 29608022 Ivermectin and permethrin for treating scabies. 1 0 1
3387 10796757 Antibiotics for acute bacterial conjunctivitis. 1 0 1
3389 28937705 Interventions for treating genital Chlamydia trachomatis infection in pregnancy. 2 0 1
3391 16856012 Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis. 1 0 1
3392 20091517 Dietary interventions for phenylketonuria. 1 0 1
3393 25723866 Protein substitute for children and adults with phenylketonuria. 3 0 1
3394 25812600 Sapropterin dihydrochloride for phenylketonuria. 1 0 1
3395 23737086 Tyrosine supplementation for phenylketonuria. 1 0 1
3398 17636649 Danazol for heavy menstrual bleeding. 1 0 1
3432 18254092 Continuous infusion versus intermittent bolus doses of indomethacin for patent ductus arteriosus closure in symptomatic preterm infants. 7 0 1
3430 29499081 Beta-blockers for prevention and treatment of retinopathy of prematurity in preterm infants. 2 0 1
3344 10796457 Calcitonin for the treatment and prevention of corticosteroid-induced osteoporosis. 2 0 1
3429 19370635 Antistaphylococcal immunoglobulins to prevent staphylococcal infection in very low birth weight infants. 3 0 1
3346 16625624 Calcium supplementation for improving bone mineral density in children. 1 0 1
3347 14974070 Calcium supplementation on bone loss in postmenopausal women. 1 0 1
3348 24599707 Chinese herbal medicines for treating osteoporosis. 1 0 1
3349 12535486 Closed reduction methods for treating distal radial fractures in adults. 1 0 1
3339 12137688 Anaesthesia for treating distal radial fracture in adults. 1 0 1
3380 22161382 Conservative prevention and management of pelvic organ prolapse in women. 1 0 1
3381 15106231 Mechanical devices for pelvic organ prolapse in women. 1 0 1
3382 30121957 Perioperative interventions in pelvic organ prolapse surgery. 1 0 1
3415 29431861 Non-steroidal anti-inflammatory agents to induce regression and prevent the progression of cervical intraepithelial neoplasia. 3 0 1
3416 27428114 Pain relief for women with cervical intraepithelial neoplasia undergoing colposcopy treatment. 1 0 1
3417 24302546 Surgery for cervical intraepithelial neoplasia. 1 0 1
3418 18843726 Acyclovir for treating primary herpetic gingivostomatitis. 1 0 1
3420 19588350 Antiviral agents for treatment of herpes simplex virus infection in neonates. 4 0 1
3421 28967695 Intravenous immunoglobulin for the treatment of childhood encephalitis. 7 0 1
3424 19160309 High versus low dose of initial thyroid hormone replacement for congenital hypothyroidism. 2 0 1
3425 27594276 Statins for aortic valve stenosis. 2 0 1
3426 17253521 Creatine for treating muscle disorders. 2 0 1
3414 24302533 Interventions for preventing blood loss during the treatment of cervical intraepithelial neoplasia. 3 0 1
3427 25391139 Pharmacological and nutritional treatment for McArdle disease (Glycogen Storage Disease type V). 3 0 1
3399 22513939 Drug treatment for spinal muscular atrophy type I. 3 0 1
3400 22513940 Drug treatment for spinal muscular atrophy types II and III. 3 0 1
3401 26691378 Interventions for central serous chorioretinopathy: a network meta-analysis. 1 0 1
3402 21563155 Interventions for infantile haemangiomas (strawberry birthmarks) of the skin. 1 0 1
3258 26982236 Forward thinking: where next for delirium prevention research? 1 0 1
3260 17443600 Interventions for preventing delirium in hospitalised patients. 2 0 1
3261 24488526 Interventions for preventing delirium in older people in institutional long-term care. 1 0 1
3262 30484283 Interventions for preventing intensive care unit delirium in adults. 1 0 1
3263 30129968 Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. 2 0 1
3264 15106152 Multidisciplinary team interventions for delirium in patients with chronic cognitive impairment. 1 0 1
3265 28553701 Opioid antagonists with minimal sedation for opioid withdrawal. 1 0 1
3266 25879099 Palliative pharmacological sedation for terminally ill adults. 1 0 1
3267 29761891 Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and cognitive dysfunction following non-cardiac and non-neurosurgical procedures in adults. 2 0 1
3257 25212274 Effects of sevoflurane versus other general anaesthesia on emergence agitation in children. 1 0 1
3268 11034735 Subjective barriers to prevent wandering of cognitively impaired people. 1 0 1
3244 19160273 Open versus laparoscopic (assisted) ileo pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis. 3 0 1
3242 14583988 Vitamin E supplementation for prevention of morbidity and mortality in preterm infants. 5 0 1
3219 22972055 Progestogens with or without oestrogen for irregular uterine bleeding associated with anovulation. 3 0 1
3220 14973957 Pulsatile gonadotrophin releasing hormone for ovulation induction in subfertility associated with polycystic ovary syndrome. 3 0 1
3221 10796718 Pulsatile luteinising hormone releasing hormone for ovulation induction in subfertility associated with polycystic ovary syndrome. 3 0 1
3222 11406034 Recombinant FSH versus urinary gonadotrophins or recombinant FSH for ovulation induction in subfertility associated with polycystic ovary syndrome. 2 0 1
3223 28349511 Risk of endometrial cancer in women treated with ovary-stimulating drugs for subfertility. 4 0 1
3224 26020622 Zinc supplementation for the prevention of type 2 diabetes mellitus in adults with insulin resistance. 6 0 1
3256 15106261 Drug therapy for delirium in terminally ill patients. 2 0 1
3245 25879090 Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients. 1 0 1
3255 23152226 Drug therapy for delirium in terminally ill adult patients. 1 0 1
3438 10796266 Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome. 4 0 1
3404 27577677 Local oestrogen for vaginal atrophy in postmenopausal women. 3 0 1
3405 17253578 Management of the fractured edentulous atrophic mandible. 1 0 1
3406 30821348 Physical exercise training for type 3 spinal muscular atrophy. 4 0 1
3407 24234875 Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding. 3 0 1
3408 10796747 Pre-operative endometrial thinning agents before hysteroscopic surgery for heavy menstrual bleeding. 1 0 1
3409 23450594 Progestogens or progestogen-releasing intrauterine systems for uterine fibroids. 2 0 1
3410 17943761 Progestogens versus oestrogens and progestogens for irregular uterine bleeding associated with anovulation. 3 0 1
3327 24194433 Pimozide for schizophrenia or related psychoses. 4 0 1
3326 10796559 Newer atypical antipsychotic medication versus clozapine for schizophrenia. 1 0 1
3254 25005604 Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive mechanical ventilation. 1 0 1
3324 27045703 Chlorpromazine versus atypical antipsychotic drugs for schizophrenia. 2 0 1
3246 17443602 Antipsychotics for delirium. 3 0 1
3248 20238336 Benzodiazepines for alcohol withdrawal. 2 0 1
3249 19821364 Benzodiazepines for delirium. 1 0 1
3250 29464690 BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the intensive care unit and its impact on clinical outcomes and resource utilization. 2 0 1
3251 18254077 Cholinesterase inhibitors for delirium. 1 0 1
3252 29952000 Cholinesterase inhibitors for the treatment of delirium in non-ICU settings. 2 0 1
3253 29385235 Comprehensive geriatric assessment for older people admitted to a surgical service. 1 0 1
3345 10796394 Calcium and vitamin D for corticosteroid-induced osteoporosis. 1 0 1
3343 22972105 Black cohosh (Cimicifuga spp.) for menopausal symptoms. 3 0 1
3490 11406028 Early volume expansion versus inotrope for prevention of morbidity and mortality in very preterm infants. 1 0 1
2200 29243813 Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. 2 0 1
2172 18425935 Pancreaticoduodenectomy (classic Whipple) versus pylorus-preserving pancreaticoduodenectomy (pp Whipple) for surgical treatment of periampullary and pancreatic carcinoma. 2 0 1
2171 27043078 Laparoscopic versus open distal pancreatectomy for pancreatic cancer. 4 0 1
2170 30246878 Insulin and glucose-lowering agents for treating people with diabetes and chronic kidney disease. 8 0 1
2146 17943864 Interventions for sexual dysfunction following treatments for cancer. 3 0 1
2147 29360138 Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers. 2 0 1
2148 28895658 Laparoscopic and robotic-assisted versus open radical prostatectomy for the treatment of localised prostate cancer. 2 0 1
2149 10796804 Maximal androgen blockade for advanced prostate cancer. 2 0 1
2150 17054269 Neo-adjuvant and adjuvant hormone therapy for localised and locally advanced prostate cancer. 1 0 1
2151 24979481 Non-steroidal antiandrogen monotherapy compared with luteinising hormone-releasing hormone agonists or surgical castration monotherapy for advanced prostate cancer. 1 0 1
2152 30352488 Penile rehabilitation for postprostatectomy erectile dysfunction. 1 0 1
2153 29683475 Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with pelvic radiotherapy in adults. 1 0 1
2154 29845595 Primary cryotherapy for localised or locally advanced prostate cancer. 2 0 1
2155 24368598 Psychosocial interventions for men with prostate cancer. 1 0 1
2157 25835541 Reiki for depression and anxiety. 1 0 1
2158 23440794 Screening for prostate cancer. 1 0 1
2159 24475492 Screening for prostate cancer: shaping the debate on benefits and harms. 1 0 1
2160 30909317 Systematic screening and assessment of psychosocial well-being and care needs of people with cancer. 3 0 1
2161 30320443 Taxane-based chemohormonal therapy for metastatic hormone-sensitive prostate cancer. 2 0 1
2162 30556597 Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life. 2 0 1
2186 26661940 Urethral (indwelling or intermittent) or suprapubic routes for short-term catheterisation in hospitalised adults. 2 0 1
2199 17943857 Antidepressants for neuropathic pain. 3 0 1
3341 10796432 Bisphosphonates for steroid induced osteoporosis. 2 0 1
2198 15266476 Anticonvulsant drugs for migraine prophylaxis. 1 0 1
2143 17943832 Intermittent versus continuous androgen suppression for prostatic cancer. 4 0 1
2145 28983908 Interventions for managing medication-related osteonecrosis of the jaw. 3 0 1
2175 15266485 Supportive care for patients with gastrointestinal cancer. 2 0 1
2176 20393967 Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries. 2 0 1
2177 21249687 Anti-inflammatory medications for obstructive sleep apnea in children. 4 0 1
2178 26943923 Enzyme replacement therapy with galsulfase for mucopolysaccharidosis type VI. 7 0 1
2179 23983011 Opioids compared to placebo or other treatments for chronic low-back pain. 2 0 1
2180 30798570 Corticosteroids as adjunctive therapy in the treatment of influenza. 2 0 1
2181 16235326 Interventions to improve antibiotic prescribing practices for hospital inpatients. 1 0 1
2182 23744516 Nutritional screening for improving professional practice for patient outcomes in hospital and primary care settings. 1 0 1
2184 25248140 Types of indwelling urethral catheters for short-term catheterisation in hospitalised adults. 2 0 1
2173 26905229 Pylorus-preserving pancreaticoduodenectomy (pp Whipple) versus pancreaticoduodenectomy (classic Whipple) for surgical treatment of periampullary and pancreatic carcinoma. 2 0 1
2185 18425896 Types of urethral catheters for management of short-term voiding problems in hospitalised adults. 2 0 1
2189 23543520 Infant position in neonates receiving mechanical ventilation. 1 0 1
2190 26677103 Interventions for treating traumatised ankylosed permanent front teeth. 1 0 1
2193 11279710 Acupuncture for idiopathic headache. 1 0 1
2194 19160193 Acupuncture for migraine prophylaxis. 1 0 1
2195 19160338 Acupuncture for tension-type headache. 1 0 1
2197 16034857 Anticonvulsant drugs for acute and chronic pain. 4 0 1
2163 27689801 Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy. 2 0 1
2165 29557103 Chemotherapy and radiotherapy for advanced pancreatic cancer. 3 0 1
2166 16855985 Chemotherapy and radiotherapy for inoperable advanced pancreatic cancer. 2 0 1
2167 27631326 Diagnostic accuracy of different imaging modalities following computed tomography (CT) scanning for assessing the resectability with curative intent in pancreatic and periampullary cancer. 3 0 1
3375 25822346 Surgical interventions for treating distal tibial metaphyseal fractures in adults. 1 0 1
3376 26964506 Treatment for osteoporosis in people with ß-thalassaemia. 3 0 1
3377 19370554 Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis. 1 0 1
3368 20464719 Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period. 1 0 1
3379 17054190 Conservative management of pelvic organ prolapse in women. 1 0 1
3352 24519664 Dietary interventions for preventing complications in idiopathic hypercalciuria. 2 0 1
3350 12804395 Conservative interventions for treating distal radial fractures in adults. 1 0 1
3328 19370666 Pimozide for tics in Tourette's syndrome. 1 0 1
3329 25866243 Pyridoxal 5 phosphate for neuroleptic-induced tardive dyskinesia. 2 0 1
3330 27078222 Risperidone (depot) for schizophrenia. 2 0 1
3331 16625629 Risperidone versus olanzapine for schizophrenia. 3 0 1
3332 17636833 Testosterone for schizophrenia. 3 0 1
3333 15106171 Drug treatment for facioscapulohumeral muscular dystrophy. 2 0 1
3334 19588347 Rehabilitation interventions for foot drop in neuromuscular disease. 6 0 1
3335 20091543 Scapular fixation in muscular dystrophy. 2 0 1
3337 25906204 Planned early delivery versus expectant management for monoamniotic twins. 4 0 1
3351 18254098 Corticosteroids for the long-term treatment in multiple sclerosis. 3 0 1
3338 30480776 Adverse side effects of dexamethasone in surgical patients. 3 0 1
3340 22161446 Bisphosphonates for osteoporosis in primary biliary cirrhosis. 3 0 1
3374 12917953 Surgical interventions for treating distal radial fractures in adults. 1 0 1
3373 24960023 Steroidal contraceptives: effect on bone fractures in women. 1 0 1
3372 27115214 Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis. 3 0 1
3361 20091583 Interventions for improving the appropriate use of imaging in people with musculoskeletal conditions. 1 0 1
2169 26837472 Duodenum-preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis. 3 0 1
2144 20464744 Interventions for improving the adoption of shared decision making by healthcare professionals. 1 0 1
2768 19370690 Honey and lozenges for children with non-specific cough. 3 0 1
2770 26252373 Interventions for prevention of herpes simplex labialis (cold sores on the lips). 2 0 1
2771 24453061 Yellow fever vaccine for patients with HIV infection. 1 0 1
3356 11687195 Etidronate for treating and preventing postmenopausal osteoporosis. 1 0 1
3359 15846681 Glucocorticosteroids for primary biliary cirrhosis. 4 0 1
3360 22161447 Hormone replacement for osteoporosis in women with primary biliary cirrhosis. 3 0 1
3362 17443607 Interventions for the treatment of decreased bone mineral density associated with HIV infection. 1 0 1
3371 27113367 Short-course oral steroids alone for chronic rhinosinusitis. 2 0 1
3363 28117876 Interventions to prevent and treat corticosteroid-induced osteoporosis and prevent osteoporotic fractures in Duchenne muscular dystrophy. 3 0 1
3364 27545902 Nutritional interventions for survivors of childhood cancer. 2 0 1
3365 20824855 Oestrogens for treatment or prevention of pelvic organ prolapse in postmenopausal women. 3 0 1
3366 16034972 Oral corticosteroids for stable chronic obstructive pulmonary disease. 2 0 1
3354 25698124 Email for clinical communication between healthcare professionals. 1 0 1
3367 30399208 Percutaneous vertebroplasty for osteoporotic vertebral compression fracture. 3 0 1
3369 26403335 Rehabilitation for distal radial fractures in adults. 1 0 1
3370 14584020 Risedronate for the prevention and treatment of postmenopausal osteoporosis. 1 0 1
3225 17253560 Zinc supplementation for the prevention of type 2 diabetes mellitus. 6 0 1
3228 29192423 Bisphosphonates for Paget's disease of bone in adults. 3 0 1
3230 16625650 Adjuvant chemotherapy for invasive bladder cancer (individual patient data). 3 0 1
3632 20464737 Action plans with limited patient education only for exacerbations of chronic obstructive pulmonary disease. 1 0 1
3634 27583824 Admission avoidance hospital at home. 1 0 1
3635 12519615 Anti-cholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease. 1 0 1
3637 24105424 Beclometasone for chronic obstructive pulmonary disease. 1 0 1
3638 12519593 Benzodiazepines and related drugs for insomnia in palliative care. 4 0 1
3640 27569680 Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD. 1 0 1
3641 10796474 Bronchopulmonary hygiene physical therapy for chronic obstructive pulmonary disease and bronchiectasis. 2 0 1
3642 28230230 Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease. 2 0 1
3630 16235392 Action plans for chronic obstructive pulmonary disease. 1 0 1
3643 11279770 Carbonic anhydrase inhibitors for hypercapnic ventilatory failure in chronic obstructive pulmonary disease. 2 0 1
3645 21412920 Combination inhaled steroid and long-acting beta(2)-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease. 1 0 1
3646 23728670 Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease. 1 0 1
3647 27271056 Combination inhaled steroid and long-acting beta₂-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease. 2 0 1
3648 30536566 Combined aclidinium bromide and long-acting beta2-agonist for chronic obstructive pulmonary disease (COPD). 2 0 1
3649 15266502 Combined corticosteroid and long acting beta-agonist in one inhaler for chronic obstructive pulmonary disease. 1 0 1
3651 17943917 Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease. 1 0 1
3652 17943918 Combined corticosteroid and long-acting beta-agonist in one inhaler versus long-acting beta-agonists for chronic obstructive pulmonary disease. 1 0 1
3653 17943798 Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease. 1 0 1
3654 24214176 Combined corticosteroid and long-acting beta₂-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease. 1 0 1
3644 11869646 Cardioselective beta-blockers for reversible airway disease. 1 0 1
3633 30306545 Active mind-body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with chronic obstructive pulmonary disease. 2 0 1
3599 24652601 Interventions based on the Theory of Mind cognitive model for autism spectrum disorder (ASD). 2 0 1
3243 15106236 Non steroidal anti-inflammatory drugs (NSAID) and Aspirin for preventing colorectal adenomas and carcinomas. 1 0 1
3598 27737490 Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD). 2 0 1
3553 23862185 Galantamine for vascular cognitive impairment. 3 0 1
3554 23543524 Ginkgo biloba for tinnitus. 3 0 1
3555 12137718 Hormone replacement therapy to maintain cognitive function in women with dementia. 1 0 1
3556 25740785 Mini-Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI). 4 0 1
3557 23728651 Rivastigmine for vascular cognitive impairment. 2 0 1
3558 12076438 Bisphosphonates for the relief of pain secondary to bone metastases. 1 0 1
3572 15106252 Inhaled cromones for prolonged non-specific cough in children. 1 0 1
3559 16856000 Calcitonin for metastatic bone pain. 1 0 1
3561 24085657 Enzyme replacement therapy with laronidase (Aldurazyme) for treating mucopolysaccharidosis type I. 7 0 1
3562 30387126 Caseworker-assigned discharge plans to prevent hospital readmission for acute exacerbations in children with chronic respiratory illness. 2 0 1
3563 25242448 Clinical pathways for chronic cough in children. 1 0 1
3564 29889304 Dual antibiotics for bronchiectasis. 2 0 1
3565 26544672 Exercise training to improve exercise capacity and quality of life in people with non-malignant dust-related respiratory diseases. 4 0 1
3566 23450585 Housing improvements for health and associated socio-economic outcomes. 1 0 1
3567 19160285 Impact of tuberculosis preventive therapy on tuberculosis and mortality in HIV-infected children. 2 0 1
3569 16856075 Indoor air modification interventions for prolonged non-specific cough in children. 1 0 1
3570 14974067 Inhaled anti-cholinergics for prolonged non-specific cough in children. 1 0 1
3560 27033167 Enzyme replacement therapy with laronidase (Aldurazyme(®)) for treating mucopolysaccharidosis type I. 8 0 1
3597 18425890 Gluten- and casein-free diets for autistic spectrum disorder. 1 0 1
3628 28434203 Topiramate monotherapy for juvenile myoclonic epilepsy. 3 0 1
3627 30687937 Topiramate for juvenile myoclonic epilepsy. 3 0 1
3626 24254932 Antiepileptic drugs for the treatment of severe myoclonic epilepsy in infancy. 3 0 1
3600 16034901 Intravenous secretin for autism spectrum disorder. 3 0 1
3547 15846729 Anticoagulants for the treatment of recurrent pregnancy loss in women without antiphospholipid syndrome. 2 0 1
3546 29460276 Surgery for trigger finger. 1 0 1
3468 20927720 Antithrombotic drugs for carotid artery dissection. 1 0 1
3469 25879115 Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. 3 0 1
3470 12917935 Interventions for herpes simplex virus epithelial keratitis. 3 0 1
3471 27902849 Oral antivirals for preventing recurrent herpes simplex keratitis in people with corneal grafts. 4 0 1
3472 22786503 Orbital radiotherapy for adult thyroid eye disease. 1 0 1
3473 22161415 Surgical orbital decompression for thyroid eye disease. 2 0 1
3474 18254009 Therapeutic interventions for herpes simplex virus epithelial keratitis. 3 0 1
3475 30480323 Tocilizumab for thyroid eye disease. 2 0 1
3476 15266431 Surgery or embolisation for varicocele in subfertile men. 1 0 1
3467 30912133 Vaccines for preventing rotavirus diarrhoea: vaccines in use. 1 0 1
3478 27669661 Medical interventions for the prevention of platinum-induced hearing loss in children with cancer. 3 0 1
3480 17443623 Nitric oxide for preventing pre-eclampsia and its complications. 3 0 1
3482 25342124 Anti-vascular endothelial growth factor for diabetic macular oedema. 3 0 1
3484 23440840 Anti-vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion. 3 0 1
3485 23235642 Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema. 2 0 1
3488 29543992 Different lasers and techniques for proliferative diabetic retinopathy. 2 0 1
3489 12535415 Dipyridamole for preventing stroke and other vascular events in patients with vascular disease. 2 0 1
3548 19160241 Aspirin or anticoagulants for treating recurrent miscarriage in women without antiphospholipid syndrome. 3 0 1
3549 15106147 Cytidinediphosphocholine (CDP choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. 2 0 1
3625 28521067 Antiepileptic drugs for the treatment of infants with severe myoclonic epilepsy. 4 0 1
3609 22786515 Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD). 1 0 1
3601 22513913 Intravenous secretin for autism spectrum disorders (ASD). 1 0 1
3602 16625601 Music therapy for autistic spectrum disorder. 1 0 1
3603 24936966 Music therapy for people with autism spectrum disorder. 2 0 1
3604 22071839 Omega-3 fatty acids supplementation for autism spectrum disorders (ASD). 1 0 1
3605 12535477 Parent-mediated early intervention for young children with autism spectrum disorder. 2 0 1
3606 23633377 Parent-mediated early intervention for young children with autism spectrum disorders (ASD). 1 0 1
3607 17253538 Risperidone for autism spectrum disorder. 2 0 1
3608 23959778 Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). 1 0 1
3610 22696338 Antifungal therapy for newborn infants with invasive fungal infection. 2 0 1
3623 27169520 Systemic antifungal therapy for tinea capitis in children. 2 0 1
3611 14974045 Systemic antifungal drugs for invasive fungal infection in preterm infants. 2 0 1
3612 29845610 Stent placement versus surgical palliation for adults with malignant gastric outlet obstruction. 1 0 1
3614 10796761 Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer. 2 0 1
3615 30095168 Home parenteral nutrition for people with inoperable malignant bowel obstruction. 1 0 1
3616 26727399 Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer. 3 0 1
3618 10908558 Carbamazepine versus valproate monotherapy for epilepsy. 2 0 1
3619 16625587 Oxcarbazepine versus phenytoin monotherapy for epilepsy. 1 0 1
3620 25685898 Loop diuretics for patients receiving blood transfusions. 1 0 1
3552 12804479 Electroconvulsive therapy for the depressed elderly. 4 0 1
3551 11406005 Efficacy and safety of nicotine on Alzheimer's disease patients. 2 0 1
3550 15846601 Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. 3 0 1
3276 24639018 Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy. 1 0 1
3310 30306544 Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia. 2 0 1
3300 28884476 Probiotics for preventing urinary tract infection in people with neuropathic bladder. 3 0 1
3311 30480763 Phosphodiesterase inhibitors for lower urinary tract symptoms consistent with benign prostatic hyperplasia. 2 0 1
3315 12519611 Terazosin for benign prostatic hyperplasia. 2 0 1
3316 14973951 Antibiotics for acute otitis media in children. 1 0 1
3317 26923064 Antibiotics for preventing suppurative complications from undifferentiated acute respiratory infections in children under five years of age. 2 0 1
3318 25330045 Acupuncture for schizophrenia. 3 0 1
3319 12076408 Amisulpride for schizophrenia. 2 0 1
3320 29409162 Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia. 1 0 1
3321 24385408 Aripiprazole versus other atypical antipsychotics for schizophrenia. 2 0 1
3322 26599405 Asenapine versus placebo for schizophrenia. 5 0 1
3323 28407198 Chlorpromazine dose for people with schizophrenia. 2 0 1
3314 29161773 Silodosin for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia. 2 0 1
3299 28731207 Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients. 2 0 1
3298 30932167 Long-term antibiotics for preventing recurrent urinary tract infection in children. 1 0 1
3297 26221993 Interventions for preventing recurrent urinary tract infection during pregnancy. 2 0 1
3272 23996298 Abdominal lift for laparoscopic cholecystectomy. 1 0 1
3273 28635028 Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery. 1 0 1
3274 21249696 Heated CO(2) with or without humidification for minimally invasive abdominal surgery. 2 0 1
3309 22972068 Microwave thermotherapy for benign prostatic hyperplasia. 2 0 1
3308 10796739 Cernilton for benign prostatic hyperplasia. 2 0 1
3306 30759311 Aquablation of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia. 2 0 1
3240 25626128 Screening with urinary dipsticks for reducing morbidity and mortality. 3 0 1
3231 21491413 Gemcitabine for unresectable, locally advanced or metastatic bladder cancer. 5 0 1
3233 12917955 Intravesical bacillus Calmette-Guerin versus mitomycin C for Ta and T1 bladder cancer. 1 0 1
3234 21563157 Intravesical Bacillus Calmette-Guérin versus epirubicin for Ta and T1 bladder cancer. 3 0 1
3235 28268259 Intravesical Bacillus Calmette-Guérin with interferon-alpha versus intravesical Bacillus Calmette-Guérin for treating non-muscle-invasive bladder cancer. 4 0 1
3236 28898400 Intravesical electromotive drug administration for non-muscle invasive bladder cancer. 4 0 1
3237 22259002 Intravesical gemcitabine for non-muscle invasive bladder cancer. 1 0 1
3238 15846746 Neoadjuvant chemotherapy for invasive bladder cancer. 3 0 1
3239 10796791 Neoadjuvant cisplatin for advanced bladder cancer. 1 0 1
3241 11869621 Surgery versus radiotherapy for muscle invasive bladder cancer. 1 0 1
3305 27090883 Urinary alkalisation for symptomatic uncomplicated urinary tract infection in women. 2 0 1
3232 11034738 Intravesical Bacillus Calmette-Guerin in Ta and T1 Bladder Cancer. 1 0 1
3269 10908517 Thioridazine for schizophrenia. 3 0 1
3270 30075057 Diagnostic tests for autism spectrum disorder (ASD) in preschool children. 5 0 1
3271 22786486 Positioning for acute respiratory distress in hospitalised infants and children. 1 0 1
3301 25603480 Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children. 1 0 1
3302 25679346 Routine blood cultures in the management of pyelonephritis in pregnancy for improving outcomes. 1 0 1
3303 25479008 Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing cesarean delivery. 2 0 1
3304 21249652 Treatments for symptomatic urinary tract infections during pregnancy. 1 0 1
3275 30699235 Interventions to reduce shoulder pain following gynaecological laparoscopic procedures. 1 0 1
3277 24668032 Methods of intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy. 1 0 1
3571 16235355 Inhaled corticosteroids for non-specific chronic cough in children. 1 0 1
3278 28374886 Total intravenous anaesthesia versus inhalational anaesthesia for adults undergoing transabdominal robotic assisted laparoscopic surgery. 2 0 1
3579 16034969 Methylxanthines for prolonged non-specific cough in children. 1 0 1
3580 10796798 Nebulised hypertonic saline for cystic fibrosis. 1 0 1
3581 27606629 Oral health education (advice and training) for people with serious mental illness. 1 0 1
3582 11279699 Orthodontic treatment for posterior crossbites. 1 0 1
3583 10796087 Prenatal thyrotropin-releasing hormone for preterm birth. 2 0 1
3574 28045472 Inhaled nitric oxide for respiratory failure in preterm infants. 4 0 1
3584 27315509 Prophylactic nasal continuous positive airway pressure for preventing morbidity and mortality in very preterm infants. 3 0 1
1007 12917965 Treatments for gestational diabetes and impaired glucose tolerance in pregnancy. 1 0 1
3587 20166097 Singing for children and adults with bronchiectasis. 3 0 1
3588 24265169 Thyrotropin-releasing hormone added to corticosteroids for women at risk of preterm birth for preventing neonatal respiratory disease. 2 0 1
3590 21901712 Acupuncture for autism spectrum disorders (ASD). 1 0 1
3591 22161380 Auditory integration training and other sound therapies for autism spectrum disorders (ASD). 1 0 1
3592 26106752 Chelation for autism spectrum disorder (ASD). 1 0 1
3593 16235322 Combined vitamin B6-magnesium treatment in autism spectrum disorder. 2 0 1
3594 30395694 Communication interventions for autism spectrum disorder in minimally verbal children. 2 0 1
3595 29742275 Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD). 1 0 1
3585 26058963 Regional (spinal, epidural, caudal) versus general anaesthesia in preterm infants undergoing inguinal herniorrhaphy in early infancy. 2 0 1
3596 28509404 Family therapy for autism spectrum disorders. 2 0 1
3573 14583933 Inhaled long acting beta agonists for stable chronic asthma. 1 0 1
3578 24127118 Long-acting beta2-agonists for chronic obstructive pulmonary disease. 2 0 1
3577 17253458 Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid. 2 0 1
3576 16625643 Leukotriene receptor antagonist for prolonged non-specific cough in children. 1 0 1
3289 18253993 Interventions for minimal change disease in adults with nephrotic syndrome. 2 0 1
3279 25734590 Cholinesterase inhibitors for rarer dementias associated with neurological conditions. 7 0 1
3280 19588392 Therapeutic interventions for disease progression in Huntington's disease. 1 0 1
3281 20927757 Anti-vascular endothelial growth factor for macular edema secondary to central retinal vein occlusion. 2 0 1
3283 19821373 Cannabinoids for Tourette's Syndrome. 1 0 1
3284 28129459 Corticosteroids for the treatment of Kawasaki disease in children. 3 0 1
3286 17054199 Salicylate for the treatment of Kawasaki disease in children. 2 0 1
3287 24763974 Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B. 1 0 1
3288 18646090 Immunosuppressive treatment for focal segmental glomerulosclerosis in adults. 4 0 1
3290 18254005 Non-corticosteroid treatment for nephrotic syndrome in children. 1 0 1
3575 26171905 Interventions for bronchiectasis: an overview of Cochrane systematic reviews. 3 0 1
3291 28837221 Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults. 2 0 1
3292 11869656 Tryptophan and 5-hydroxytryptophan for depression. 2 0 1
3295 15846726 Duration of antibacterial treatment for uncomplicated urinary tract infection in women. 2 0 1
3296 26560337 Duration of treatment for asymptomatic bacteriuria during pregnancy. 2 0 1
3325 24515383 Dopamine agents for hepatic encephalopathy. 4 0 1
3439 11687095 Early versus late discontinuation of oxygen in preterm or low birth weight infants. 2 0 1
3440 23076909 Early versus late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. 2 0 1
3441 22419305 Enteral iron supplementation in preterm and low birth weight infants. 2 0 1
1006 24782359 Techniques of monitoring blood glucose during pregnancy for women with pre-existing diabetes. 1 0 1
5864 26501380 Interventions for smokeless tobacco use cessation. 1 0 1
1009 30103263 Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews. 4 0 1
4176 15846663 Group based training for self-management strategies in people with type 2 diabetes mellitus. 2 0 1
4180 27640062 Insulin monotherapy compared with the addition of oral glucose-lowering agents to insulin for people with type 2 diabetes already on insulin therapy and inadequate glycaemic control. 2 0 1
4181 15495054 Insulin monotherapy versus combinations of insulin with oral hypoglycaemic agents in patients with type 2 diabetes mellitus. 2 0 1
4182 15846672 Interventions for improving adherence to treatment recommendations in people with type 2 diabetes mellitus. 2 0 1
4183 17443605 Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus. 2 0 1
4170 17636747 Dietary advice for treatment of type 2 diabetes mellitus in adults. 2 0 1
4101 26252202 Total or near-total thyroidectomy versus subtotal thyroidectomy for multinodular non-toxic goitre in adults. 3 0 1
4316 28504325 Therapeutic ultrasound for venous leg ulcers. 1 0 1
4318 24353155 Local versus general anaesthesia for carotid endarterectomy. 2 0 1
4455 12804391 Interventions for treating trichomoniasis in women. 2 0 1
4456 21563127 Interventions for trichomoniasis in pregnancy. 2 0 1
4457 21975773 Natalizumab for relapsing remitting multiple sclerosis. 3 0 1
4459 18646136 Acupuncture for dysphagia in acute stroke. 2 0 1
4460 24801118 Botulinum toxin for upper oesophageal sphincter dysfunction in neurological swallowing disorders. 2 0 1
4461 17943817 Early versus delayed (traditional) oral fluids and food for reducing complications after major abdominal gynaecologic surgery. 2 0 1
4462 25502897 Early versus delayed oral fluids and food for reducing complications after major abdominal gynaecologic surgery. 2 0 1
4463 28898404 High versus standard volume enteral feeds to promote growth in preterm or low birth weight infants. 5 0 1
4464 29987845 Interventions for the treatment of brain radionecrosis after radiotherapy or radiosurgery. 1 0 1
4465 30191961 Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants. 2 0 1
4467 16625621 Rapid versus slow withdrawal of antiepileptic drugs. 2 0 1
4178 19160249 Individual patient education for people with type 2 diabetes mellitus. 2 0 1
4175 21975753 Glucagon-like peptide analogues for type 2 diabetes mellitus. 2 0 1
4204 25586198 Palliative radiotherapy regimens for patients with thoracic symptoms from non-small cell lung cancer. 4 0 1
4174 25686270 Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. 1 0 1
4206 22696321 Abdominal decompression in normal pregnancy. 2 0 1
4208 20687086 Alternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia. 2 0 1
4209 26184394 Alternative versus standard packages of antenatal care for low-risk pregnancy. 2 0 1
4187 15674929 Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus. 3 0 1
4186 18254017 Omega-3 polyunsaturated fatty acids (PUFA) for type 2 diabetes mellitus. 2 0 1
4185 22895968 Momordica charantia for type 2 diabetes mellitus. 2 0 1
4184 17443551 Meglitinide analogues for type 2 diabetes mellitus. 2 0 1
4157 12137644 Interventions in the management of serum lipids for preventing stroke recurrence. 1 0 1
4158 24711093 Screening for peripheral arterial disease. 2 0 1
4159 19370582 Statins for the prevention of dementia. 1 0 1
4160 15846673 Alpha-glucosidase inhibitors for type 2 diabetes mellitus. 3 0 1
4161 15266492 Chinese herbal medicines for type 2 diabetes mellitus. 2 0 1
4162 23235674 Colesevelam for type 2 diabetes mellitus. 2 0 1
4163 22161431 Computer-assisted versus oral-and-written family history taking for identifying people with elevated risk of type 2 diabetes mellitus. 2 0 1
4164 23543567 Computer-based diabetes self-management interventions for adults with type 2 diabetes mellitus. 2 0 1
4166 18646153 Culturally appropriate health education for type 2 diabetes mellitus in ethnic minority groups. 2 0 1
4314 27977053 Protease-modulating matrix treatments for healing venous leg ulcers. 1 0 1
4167 30371961 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia. 2 0 1
4171 18425967 Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus. 2 0 1
4468 29267988 Respiratory muscle training for multiple sclerosis. 2 0 1
4469 27562477 Therapeutic exercises for affecting post-treatment swallowing in people treated for advanced-stage head and neck cancers. 4 0 1
4470 23450542 Transpyloric versus gastric tube feeding for preterm infants. 4 0 1
4471 23728650 Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa. 1 0 1
4446 19160213 Nutrition support for bone marrow transplant patients. 1 0 1
4447 26301790 Nutritional support in children and young people with cancer undergoing chemotherapy. 2 0 1
4448 28722116 Opioids for cancer-related pain in children and adolescents. 2 0 1
4449 26037486 The effects of idarubicin versus other anthracyclines for induction therapy of patients with newly diagnosed leukaemia. 1 0 1
4450 30148542 Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance. 3 0 1
4452 23744347 Opioid antagonists for smoking cessation. 1 0 1
4430 29543325 Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users. 2 0 1
4477 16856018 Neoadjuvant chemoradiation for advanced primary vulvar cancer. 4 0 1
4479 10796849 Surgical interventions for early squamous cell carcinoma of the vulva. 3 0 1
4508 30357813 Gabapentin add-on treatment for drug-resistant focal epilepsy. 2 0 1
4509 22972056 Levetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane Review. 2 0 1
4510 29355908 Losigamone add-on therapy for focal epilepsy. 2 0 1
4512 30335200 Zonisamide add-on therapy for focal epilepsy. 2 0 1
4513 11869672 Deep transverse friction massage for treating tendinitis. 1 0 1
4514 12076444 Orthotic devices for treating patellofemoral pain syndrome. 1 0 1
4516 11687194 Therapeutic ultrasound for treating patellofemoral pain syndrome. 2 0 1
4518 29064090 Different communication strategies for disclosing a diagnosis of schizophrenia and related disorders. 4 0 1
4519 25997589 Treatments for delusional disorder. 1 0 1
4520 27820878 Integrated versus non-integrated orbital implants for treating anophthalmic sockets. 1 0 1
4445 25061777 Mycophenolate mofetil versus methotrexate for prevention of graft-versus-host disease in people receiving allogeneic hematopoietic stem cell transplantation. 1 0 1
4444 20687070 Interventions for treating oral mucositis for patients with cancer receiving treatment. 1 0 1
4443 20687072 Interventions for replacing missing teeth: maintaining and recovering soft tissue health around dental implants. 1 0 1
4431 28257562 Planned early birth versus expectant management for women with preterm prelabour rupture of membranes prior to 37 weeks' gestation for improving pregnancy outcome. 4 0 1
4472 21491387 Chemoradiation for advanced primary vulval cancer. 2 0 1
4473 24532092 De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma. 2 0 1
4474 26021841 Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions. 3 0 1
4475 23794286 Interventions for cutaneous Bowen's disease. 2 0 1
4454 11034678 Antibiotics for acute bronchitis. 2 0 1
4476 27943254 Minimally invasive surgery versus radiotherapy/chemoradiotherapy for small-volume primary oropharyngeal carcinoma. 3 0 1
4453 28185257 System change interventions for smoking cessation. 1 0 1
4451 28421600 Lay-led and peer support interventions for adolescents with asthma. 2 0 1
4432 28155226 Propofol versus thiopental sodium for the treatment of refractory status epilepticus. 2 0 1
4441 29181845 Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors. 2 0 1
4433 28537052 Recombinant luteinizing hormone (rLH) and recombinant follicle stimulating hormone (rFSH) for ovarian stimulation in IVF/ICSI cycles. 2 0 1
4434 29747241 Stiripentol add-on therapy for focal refractory epilepsy. 4 0 1
4435 28657646 Wendan decoction (Traditional Chinese medicine) for schizophrenia. 2 0 1
4436 28956893 Yoga versus non-standard care for schizophrenia. 2 0 1
4437 23836382 Low molecular weight heparin for prevention of microvascular occlusion in digital replantation. 1 0 1
4438 23450574 Interventions for smoking cessation and reduction in individuals with schizophrenia. 4 0 1
4439 26799001 Chinese herbal medicine for oesophageal cancer. 2 0 1
4440 21491378 Interventions for preventing oral mucositis for patients with cancer receiving treatment. 1 0 1
4205 22696313 Abdominal decompression for suspected fetal compromise/pre-eclampsia. 2 0 1
4203 17054152 Palliative radiotherapy regimens for non-small cell lung cancer. 2 0 1
4308 16034924 Urinary catheter policies for short-term bladder drainage in adults. 1 0 1
4283 28616956 Tramadol for neuropathic pain in adults. 2 0 1
4285 19588376 Corticosteroid injection for de Quervain's tenosynovitis. 1 0 1
4286 27551927 Concomitant atrial fibrillation surgery for people undergoing cardiac surgery. 3 0 1
4288 30821845 Epidural analgesia for adults undergoing cardiac surgery with or without cardiopulmonary bypass. 3 0 1
4212 25352443 Antibiotics for prelabour rupture of membranes at or near term. 4 0 1
4211 23440836 Antenatal interventions for reducing weight in obese women for improving pregnancy outcome. 2 0 1
4210 12076403 Ambulatory versus conventional methods for monitoring blood pressure during pregnancy. 2 0 1
4129 21249654 Percutaneous needle aspiration, injection, and re-aspiration with or without benzimidazole coverage for uncomplicated hepatic hydatid cysts. 1 0 1
4130 16625588 Percutaneous needle aspiration, injection, and reaspiration with or without benzimidazole coverage for uncomplicated hepatic hydatid cysts. 1 0 1
4135 12917937 Balloon angioplasty versus medical therapy for hypertensive patients with renal artery obstruction. 3 0 1
4136 30484284 Autologous platelet concentrates for treating periodontal infrabony defects. 2 0 1
4137 28362061 Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. 3 0 1
4138 19821315 Enamel matrix derivative (Emdogain(R)) for periodontal tissue regeneration in intrabony defects. 1 0 1
4139 16235343 Enamel matrix derivative (Emdogain) for periodontal tissue regeneration in intrabony defects. 1 0 1
4140 27759881 Endodontic procedures for retreatment of periapical lesions. 1 0 1
4141 18254056 Full-mouth disinfection for the treatment of adult chronic periodontitis. 1 0 1
4142 25884249 Full-mouth treatment modalities (within 24 hours) for chronic periodontitis in adults. 1 0 1
4143 16625546 Guided tissue regeneration for periodontal infra-bony defects. 1 0 1
4144 18646117 Occlusal interventions for periodontitis in adults. 1 0 1
4145 17443571 Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases. 3 0 1
4284 20464756 Treatment for leiomyosarcoma and leiomyoma in children with HIV infection. 2 0 1
4282 30673120 Pregabalin for neuropathic pain in adults. 2 0 1
4202 18254091 Whole grain foods for the prevention of type 2 diabetes mellitus. 2 0 1
4281 25737049 Physical rehabilitation for critical illness myopathy and neuropathy. 2 0 1
4310 23152202 Compression for venous leg ulcers. 1 0 1
4311 15106239 Hyperbaric oxygen therapy for chronic wounds. 1 0 1
4290 15846675 Pharmacological cardioversion for atrial fibrillation and flutter. 2 0 1
4266 29624206 Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants. 2 0 1
4289 23925867 Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation. 1 0 1
4287 11869642 Electrical cardioversion for atrial fibrillation and flutter. 1 0 1
4268 19370621 Effect of administration of antihelminthics for soil transmitted helminths during pregnancy. 2 0 1
4269 26087057 Effect of administration of antihelminthics for soil-transmitted helminths during pregnancy. 2 0 1
4270 24214100 Pharmacotherapy for trichotillomania. 1 0 1
4271 16856105 Antidepressants for the negative symptoms of schizophrenia. 2 0 1
4272 29802811 Mirtazapine adjunct for people with schizophrenia. 2 0 1
4273 11034761 Prophylactic vitamin K for vitamin K deficiency bleeding in neonates. 2 0 1
4274 29077194 Metformin for endometrial hyperplasia. 6 0 1
4275 11869645 Rapid correction of early metabolic acidaemia in comparison with placebo, no intervention or slow correction in LBW infants. 1 0 1
4276 18646138 Decompressive surgery of lower limbs for symmetrical diabetic peripheral neuropathy. 3 0 1
4277 28631805 Drug therapy for chronic idiopathic axonal polyneuropathy. 1 0 1
4278 24838845 Imipramine for neuropathic pain in adults. 2 0 1
4279 24477672 Interventions for preventing critical illness polyneuropathy and critical illness myopathy. 3 0 1
4280 25000215 Levetiracetam for neuropathic pain in adults. 2 0 1
4146 30590875 Routine scale and polish for periodontal health in adults. 4 0 1
4147 29291254 Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis. 3 0 1
4148 30259968 Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults. 2 0 1
4149 28605006 Treating periodontal disease for preventing adverse birth outcomes in pregnant women. 6 0 1
4120 10796330 Repeated lumbar or ventricular punctures for preventing disability or shunt dependence in newborn infants with intraventricular hemorrhage. 1 0 1
4121 12137677 Shunting for normal pressure hydrocephalus (NPH). 2 0 1
4123 20824879 Interventions for the treatment of keratocystic odontogenic tumours (KCOT, odontogenic keratocysts (OKC)). 1 0 1
4125 28158933 Interventions for treating simple bone cysts in the long bones of children. 2 0 1
4153 17443517 Intravenous magnesium for acute myocardial infarction. 5 0 1
4154 23076940 Antioxidants for chronic kidney disease. 4 0 1
4156 29240976 Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events. 1 0 1
4188 17253475 Phosphodiesterase inhibitors for erectile dysfunction in patients with diabetes mellitus. 3 0 1
4189 17054272 Pioglitazone for type 2 diabetes mellitus. 2 0 1
4190 28799164 Preconception care for diabetic women for improving maternal and infant health. 1 0 1
4191 17943769 Protein restriction for diabetic renal disease. 1 0 1
4192 28954185 Psychological interventions for diabetes-related distress in adults with type 2 diabetes mellitus. 2 0 1
4193 20393934 Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. 3 0 1
4196 30556900 Short-acting insulin analogues versus regular human insulin for adult, non-pregnant persons with type 2 diabetes mellitus. 2 0 1
4197 27101360 Sodium-glucose cotransporter (SGLT) 2 inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk for the development of type 2 diabetes mellitus. 2 0 1
4198 12804458 Specialist nurses in diabetes mellitus. 2 0 1
4199 24788670 Steroidal contraceptives: effect on carbohydrate metabolism in women without diabetes mellitus. 2 0 1
4200 23633364 Sulphonylurea monotherapy for patients with type 2 diabetes mellitus. 2 0 1
4201 24000051 Sweet potato for type 2 diabetes mellitus. 2 0 1
4119 17943743 Intraventricular streptokinase after intraventricular hemorrhage in newborn infants. 2 0 1
4118 23728696 Flow-regulated versus differential pressure-regulated shunt valves for adult patients with normal pressure hydrocephalus. 2 0 1
4117 12137707 Fibrinolytic therapy for intraventricular hemorrhage in adults. 1 0 1
4106 30620051 Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis. 3 0 1
4150 26545069 Treatment of periodontal disease for glycaemic control in people with diabetes mellitus. 3 0 1
4151 20464734 Treatment of periodontal disease for glycaemic control in people with diabetes. 2 0 1
4128 24941398 Levothyroxine or minimally invasive therapies for benign thyroid nodules. 4 0 1
4152 15846734 Hyperbaric oxygen therapy for acute coronary syndrome. 1 0 1
4127 23846831 Intravenous versus inhalation anaesthesia for one-lung ventilation. 1 0 1
4124 26545201 Interventions for the treatment of keratocystic odontogenic tumours. 1 0 1
4103 20393962 Interventions for non-metastatic squamous cell carcinoma of the skin. 3 0 1
4104 24163070 Interventions for the treatment of Paget's disease of the vulva. 2 0 1
4107 16235339 Albendazole for lymphatic filariasis. 2 0 1
4116 10796510 Drugs for treating neurocysticercosis (tapeworm infection of the brain). 3 0 1
4108 17253495 Diethylcarbamazine (DEC)-medicated salt for community-based control of lymphatic filariasis. 2 0 1
4109 20464765 Caffeine for the prevention of injuries and errors in shift workers. 1 0 1
4110 25267894 Interventions for preventing injuries caused by impaired alertness in individuals with jet lag and shift work disorder. 1 0 1
4111 11279722 Melatonin for preventing and treating jet lag. 1 0 1
4112 12076414 Melatonin for the prevention and treatment of jet lag. 1 0 1
4113 29498416 Workplace lighting for improving alertness and mood in daytime workers. 2 0 1
4114 29971813 Acute tocolysis for uterine tachysystole or suspected fetal distress. 1 0 1
4115 26455722 Antiepileptic drugs for seizure control in people with neurocysticercosis. 1 0 1
4521 30754073 Active versus expectant management for women in the third stage of labour. 1 0 1
4522 17443599 Antenatal phenobarbital for reducing neonatal jaundice after red cell isoimmunization. 1 0 1
4523 26334436 Anti-D administration in pregnancy for preventing Rhesus alloimmunisation. 1 0 1
4390 30407616 Cannabis for the treatment of Crohn's disease. 4 0 1
4394 24859388 Antibiotic therapy versus no antibiotic therapy for children aged two to 59 months with WHO-defined non-severe pneumonia and wheeze. 2 0 1
4396 18254083 Corticosteroids for preventing postherpetic neuralgia. 1 0 1
4397 22336836 Surfactant for bacterial pneumonia in late preterm and term infants. 2 0 1
4398 26561037 Interventions for metabolic bone disease in children with chronic kidney disease. 4 0 1
4399 24752440 Physical activity programs for promoting bone mineralization and growth in preterm infants. 2 0 1
4400 27140827 Alpha₂-adrenergic agonists for the management of opioid withdrawal. 2 0 1
4401 28658507 Antibiotics for neonates born through meconium-stained amniotic fluid. 2 0 1
4402 26848926 Antioxidant treatments for schizophrenia. 3 0 1
4391 30406638 Cannabis for the treatment of ulcerative colitis. 3 0 1
4530 23235611 Rehabilitation for hamstring injuries. 1 0 1
4100 21154350 Hyperfractionated or accelerated radiotherapy for head and neck cancer. 4 0 1
4097 30155883 Autologous cells derived from different sources and administered using different regimens for 'no-option' critical lower limb ischaemia patients. 1 0 1
3820 25691262 Altered dietary salt intake for people with chronic kidney disease. 3 0 1
3821 30277556 Antihypertensive drug therapy for mild to moderate hypertension during pregnancy. 4 0 1
3822 19588343 Antihypertensive treatment for kidney transplant recipients. 1 0 1
3823 25335553 Astragalus (a traditional Chinese medicine) for treating chronic kidney disease. 3 0 1
3824 25519252 Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease. 3 0 1
3825 15106158 Corticosteroid therapy for nephrotic syndrome in children. 1 0 1
3826 30855726 Early and late adverse renal effects after potentially nephrotoxic treatment for childhood cancer. 4 0 1
4393 16856093 Psychotherapeutic interventions for cannabis abuse and/or dependence in outpatient settings. 2 0 1
4317 19821353 Carotid endarterectomy for carotid stenosis in patients selected for coronary artery bypass graft surgery. 3 0 1
4524 24901312 Calcium channel blockers for inhibiting preterm labour and birth. 1 0 1
4389 14974077 Therapy with glatiramer acetate for multiple sclerosis. 2 0 1
4420 27126581 Gonadotrophin-releasing hormone antagonists for assisted reproductive technology. 2 0 1
4421 27149997 High frequency jet ventilation versus high frequency oscillatory ventilation for pulmonary dysfunction in preterm infants. 1 0 1
4422 27852101 Human chorionic gonadotrophin priming for fertility treatment with in vitro maturation. 2 0 1
4423 28746752 Immunotherapy for diabetic amyotrophy. 2 0 1
4424 29388198 Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI). 2 0 1
4425 28111738 Interventions for the prevention of OHSS in ART cycles: an overview of Cochrane reviews. 2 0 1
4426 30566764 Interventions for treating wrist fractures in children. 2 0 1
4407 27732740 Bifeprunox versus placebo for schizophrenia. 2 0 1
4406 28822350 Baclofen for alcohol withdrawal. 2 0 1
4405 29938790 Automated monitoring compared to standard care for the early detection of sepsis in critically ill patients. 1 0 1
4403 26915339 Assisted reproductive technologies for male subfertility. 2 0 1
4378 21154372 Antipsychotic switching for people with schizophrenia who have neuroleptic-induced weight or metabolic problems. 2 0 1
4379 17253544 Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis. 4 0 1
4380 24374462 Statins for non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. 4 0 1
4381 29761473 Glucocorticosteroids for infants with biliary atresia following Kasai portoenterostomy. 1 0 1
4384 14973987 Nitrates for achalasia. 1 0 1
4385 22336856 Surgery for congenital choanal atresia. 1 0 1
4386 20556765 Human growth hormone and glutamine for patients with short bowel syndrome. 2 0 1
4387 17943899 Microwave therapy for cervical ectropion. 3 0 1
3827 20824845 Heparin and related substances for preventing diabetic kidney disease. 2 0 1
3828 24470059 HMG CoA reductase inhibitors (statins) for kidney transplant recipients. 3 0 1
3829 24880031 HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis. 4 0 1
3830 26235292 Immunosuppressive agents for treating IgA nephropathy. 4 0 1
3805 22895935 Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis. 3 0 1
3806 26859621 Interventions for dysphagia in long-term, progressive muscle disease. 3 0 1
3807 22513954 Interventions for treating acute elbow dislocations in adults. 2 0 1
3808 15266537 Methotrexate for ankylosing spondylitis. 1 0 1
3810 17054251 Continuous positive airway pressure delivery interfaces for obstructive sleep apnoea. 1 0 1
3811 28166390 Emollients and moisturisers for eczema. 3 0 1
3812 15674885 Interventions for photodamaged skin. 1 0 1
3813 20556758 Interventions for preventing occupational irritant hand dermatitis. 1 0 1
3815 28759701 Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy. 1 0 1
3817 18425908 Excisional surgery versus ablative surgery for ovarian endometriomata. 3 0 1
3791 17636838 Therapeutic touch for anxiety disorders. 1 0 1
3841 23440822 Acupuncture for hypoxic ischemic encephalopathy in neonates. 1 0 1
3843 18425971 Allopurinol for preventing mortality and morbidity in newborn infants with suspected hypoxic-ischaemic encephalopathy. 3 0 1
3869 29542112 Laryngeal mask airway versus bag-mask ventilation or endotracheal intubation for neonatal resuscitation. 1 0 1
3870 24696187 Magnesium supplementation in pregnancy. 3 0 1
3871 12804504 Metalloporphyrins for treatment of unconjugated hyperbilirubinemia in neonates. 6 0 1
3872 14974047 Naloxone for preventing morbidity and mortality in newborn infants of greater than 34 weeks' gestation with suspected perinatal asphyxia. 2 0 1
3873 10908536 Near-infrared spectroscopy for fetal assessment during labour. 1 0 1
3874 15106187 Nonabsorbable disaccharides for hepatic encephalopathy. 2 0 1
3804 25416525 Aspiration of the elbow joint for treating radial head fractures. 3 0 1
3803 23970462 Chemotherapy for thymic carcinoma and advanced thymoma in adults. 4 0 1
3802 15674941 Botulinum toxin type B for cervical dystonia. 1 0 1
3819 24782282 Aldosterone antagonists for preventing the progression of chronic kidney disease. 3 0 1
3831 10796237 Interventions for varicosities and leg oedema in pregnancy. 3 0 1
3832 21412884 Non-immunosuppressive treatment for IgA nephropathy. 3 0 1
3833 22336824 Pentoxifylline for diabetic kidney disease. 2 0 1
3834 10796272 Plasma volume expansion for treatment of women with pre-eclampsia. 3 0 1
3835 20464745 Prostaglandin E1 for preventing the progression of diabetic kidney disease. 2 0 1
3836 29084343 Uric acid lowering therapies for preventing or delaying the progression of chronic kidney disease. 4 0 1
3837 27198122 Midazolam for sedation before procedures. 2 0 1
3838 18254073 Dietary exclusions for established atopic eczema. 4 0 1
3840 30610762 Acetyl-L-carnitine for patients with hepatic encephalopathy. 4 0 1
3801 27782297 Botulinum toxin type A versus botulinum toxin type B for cervical dystonia. 4 0 1
3818 10796530 Gonadotrophin-releasing hormone analogues for pain associated with endometriosis. 1 0 1
3816 18843668 Grommets (ventilation tubes) for recurrent acute otitis media in children. 1 0 1
3793 23881657 Intermittent drug techniques for schizophrenia. 2 0 1
3794 29144549 Zuclopenthixol dihydrochloride for schizophrenia. 3 0 1
3796 22161423 Face-down positioning or posturing after macular hole surgery. 1 0 1
3798 15674969 Botulinum toxin type A therapy for blepharospasm. 3 0 1
3799 29230798 Botulinum toxin type A therapy for cervical dystonia. 5 0 1
3800 15674939 Botulinum toxin type A versus anticholinergics for cervical dystonia. 3 0 1
4419 28349525 Glucocorticoid supplementation during ovarian stimulation for IVF or ICSI. 2 0 1
4418 29489032 Ghrelin for the management of cachexia associated with cancer. 2 0 1
4417 28349510 Fresh versus frozen embryo transfers in assisted reproduction. 2 0 1
4363 27502170 Normal saline versus lower-chloride solutions for kidney transplantation. 1 0 1
4496 27618521 Antidepressants and benzodiazepines for panic disorder in adults. 2 0 1
4498 18843701 Azithromycin for treating uncomplicated typhoid and paratyphoid fever (enteric fever). 1 0 1
4499 21975746 Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). 1 0 1
4501 18425906 Multidisciplinary rehabilitation programmes following joint replacement at the hip and knee in chronic arthropathy. 1 0 1
4502 26704192 Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions. 1 0 1
4503 23235622 Supplemental perioperative steroids for surgical patients with adrenal insufficiency. 3 0 1
4505 29862492 Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units. 2 0 1
4429 29534303 Orthodontic treatment for prominent upper front teeth (Class II malocclusion) in children and adolescents. 2 0 1
4428 29096046 Oral medications including clomiphene citrate or aromatase inhibitors with gonadotropins for controlled ovarian stimulation in women undergoing in vitro fertilisation. 2 0 1
4427 26842828 Legislative smoking bans for reducing harms from secondhand smoke exposure, smoking prevalence and tobacco consumption. 1 0 1
4352 12535396 Selegiline for Alzheimer's disease. 3 0 1
4353 10908463 Tacrine for Alzheimer's disease. 2 0 1
4354 23235635 Simple urethral dilatation, endoscopic urethrotomy, and urethroplasty for urethral stricture disease in adult men. 1 0 1
4355 29859007 Medical and surgical interventions for the treatment of urinary stones in children. 2 0 1
4357 30659577 Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery. 2 0 1
4358 26606533 Thyroid surgery for Graves' disease and Graves' ophthalmopathy. 6 0 1
4359 15846651 Base administration or fluid bolus for preventing morbidity and mortality in preterm infants with metabolic acidosis. 1 0 1
4360 17253467 Correction of chronic metabolic acidosis for chronic kidney disease patients. 4 0 1
4361 23881744 Early versus late administration of amino acids in preterm infants receiving parenteral nutrition. 1 0 1
4495 22258982 Intramedullary nailing for tibial shaft fractures in adults. 2 0 1
4494 20556771 Bone morphogenetic protein (BMP) for fracture healing in adults. 1 0 1
4491 26346107 Symphysial fundal height (SFH) measurement in pregnancy for detecting abnormal fetal growth. 1 0 1
4504 18843745 Interventions for the management of oral submucous fibrosis. 1 0 1
4525 12535434 Calcium channel blockers for inhibiting preterm labour. 1 0 1
4526 12917992 Early intravenous nutrition for the prevention of neonatal jaundice. 1 0 1
4527 11279748 Fibreoptic phototherapy for neonatal jaundice. 1 0 1
4528 26059051 Impact of Haemophilus influenzae type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes. 2 0 1
4529 30246877 Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour. 1 0 1
4507 28718878 Deep brain and cortical stimulation for epilepsy. 3 0 1
4478 11687151 Primary groin irradiation vs primary groin surgery for early vulvar cancer. 3 0 1
4506 30920649 Brivaracetam add-on therapy for drug-resistant epilepsy. 2 0 1
4480 15266429 Hormone replacement therapy in postmenopausal women: endometrial hyperplasia and irregular bleeding. 4 0 1
4490 18425914 Surfactant for pulmonary hemorrhage in neonates. 3 0 1
4481 22895916 Hormone therapy in postmenopausal women and risk of endometrial hyperplasia. 3 0 1
4482 22895965 Mifepristone for uterine fibroids. 2 0 1
4483 18254026 Pharmacological interventions for hypertensive emergencies. 1 0 1
4484 18843663 Calcium antagonists for Duchenne muscular dystrophy. 2 0 1
4486 18254031 Glucocorticoid corticosteroids for Duchenne muscular dystrophy. 2 0 1
4487 20166090 Interventions for increasing ankle range of motion in patients with neuromuscular disease. 5 0 1
4488 26384956 Interventions for heartburn in pregnancy. 1 0 1
4489 22786495 Surfactant for pulmonary haemorrhage in neonates. 3 0 1
4362 16437468 Higher versus lower protein intake in formula-fed low birth weight infants. 1 0 1
4364 28933805 Perioperative administration of buffered versus non-buffered crystalloid intravenous fluid to improve outcomes following adult surgical procedures. 1 0 1
4416 30039850 Early versus delayed antiretroviral treatment in HIV-positive people with cryptococcal meningitis. 2 0 1
4365 23235602 Perioperative buffered versus non-buffered fluid administration for surgery in adults. 3 0 1
4338 23828580 Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB. 2 0 1
4339 25306866 Acupuncture for functional dyspepsia. 2 0 1
4341 28779487 Antidepressants for chronic non-cancer pain in children and adolescents. 6 0 1
4342 22071801 Antiplatelet agents for intermittent claudication. 3 0 1
4343 16235292 Initial management strategies for dyspepsia. 1 0 1
4345 29543326 Non-invasive diagnostic tests for Helicobacter pylori infection. 2 0 1
4347 28700091 Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer pain in adults. 2 0 1
4349 11405996 Physostigmine for Alzheimer's disease. 2 0 1
4375 26014366 Dopamine agonists for the treatment of cocaine dependence. 1 0 1
4376 20166094 Efficacy of psychostimulant drugs for cocaine dependence. 1 0 1
4377 27670244 Psychostimulant drugs for cocaine dependence. 1 0 1
4408 28220474 Buprenorphine for managing opioid withdrawal. 2 0 1
4409 28387925 Chlorpromazine versus clotiapine for schizophrenia. 4 0 1
4410 28333365 Clozapine combined with different antipsychotic drugs for treatment-resistant schizophrenia. 2 0 1
4411 28613384 Communication skills training for mental health professionals working with people with severe mental illness. 2 0 1
4412 30075059 Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term. 1 0 1
4413 28334433 Dietary interventions for recurrent abdominal pain in childhood. 3 0 1
4414 27574798 Early additional food and fluids for healthy breastfed full-term infants. 3 0 1
4415 27976361 Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants. 2 0 1
4337 11869663 Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection. 1 0 1
4336 22071842 Adjuvant gonadotropin-releasing hormone analogues for the prevention of chemotherapy induced premature ovarian failure in premenopausal women. 1 0 1
4334 27824221 School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents. 2 0 1
4350 30335201 Prokinetics for functional dyspepsia. 1 0 1
4366 25822171 Strategies to increase the ownership and use of insecticide-treated bednets to prevent malaria. 2 0 1
4367 14583927 Cyproterone acetate for hirsutism. 2 0 1
4368 12535507 Interventions for mucous membrane pemphigoid and epidermolysis bullosa acquisita. 3 0 1
4370 22161371 Antidepressants for cocaine dependence and problematic cocaine use. 1 0 1
4371 12804445 Antidepressants for cocaine dependence. 1 0 1
4373 16437523 Auricular acupuncture for cocaine dependence. 1 0 1
4351 29161458 Proton pump inhibitors for functional dyspepsia. 1 0 1
4374 20091613 Disulfiram for the treatment of cocaine dependence. 1 0 1
4348 17054151 Pharmacological interventions for non-ulcer dyspepsia. 1 0 1
4332 21678366 Male circumcision for prevention of homosexual acquisition of HIV in men. 2 0 1
4319 17943745 Percutaneous transluminal angioplasty and stenting for carotid artery stenosis. 2 0 1
4320 22972047 Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis. 2 0 1
4321 29298459 Embolisation for pulmonary arteriovenous malformation. 1 0 1
4324 30353945 Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review. 2 0 1
4327 24519702 Psychological and behavioural treatments for adults with non-epileptic attack disorder. 3 0 1
4328 11687130 Specialist epilepsy nurses for treating epilepsy. 2 0 1
4329 11687127 Aciclovir for Bell's palsy (idiopathic facial paralysis). 3 0 1
4330 19821283 Antiviral treatment for Bell's palsy (idiopathic facial paralysis). 1 0 1
4309 23235639 Thrombophilia testing for prevention of recurrent venous thromboembolism. 1 0 1
4307 22895939 Urinary catheter policies for long-term bladder drainage. 1 0 1
3876 28050900 Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more). 8 0 1
6237 23633340 Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children. 1 0 1
6239 19160317 Combination formoterol and inhaled steroid versus beta2-agonist as relief medication for chronic asthma in adults and children. 1 0 1
6229 27070225 Breathing exercises for children with asthma. 1 0 1
6240 28076656 Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma. 1 0 1
6242 23760885 Dehumidifiers for chronic asthma. 2 0 1
6243 21412865 Dietary sodium manipulation and asthma. 1 0 1
6244 27176676 Different oral corticosteroid regimens for acute asthma. 1 0 1
6245 23235589 Early use of inhaled corticosteroids in the emergency department treatment of acute asthma. 1 0 1
6246 17636712 Education interventions for adults who attend the emergency room for acute asthma. 1 0 1
6247 27580628 Exhaled nitric oxide levels to guide treatment for adults with asthma. 1 0 1
6248 27825189 Exhaled nitric oxide levels to guide treatment for children with asthma. 1 0 1
6249 15846599 Family therapy for chronic asthma in children. 1 0 1
6250 16625634 Fluticasone versus HFA-beclomethasone dipropionate for chronic asthma in adults and children. 1 0 1
6241 28828760 Culture-specific programs for children and adults from minority groups who have asthma. 1 0 1
6251 20824877 Formoterol versus short-acting beta-agonists as relief medication for adults and children with asthma. 1 0 1
6228 24085551 Breathing exercises for adults with asthma. 1 0 1
6226 28402017 Asthma education for school staff. 1 0 1
6202 19160192 Neoadjuvant and adjuvant therapy for surgical resection of hepatocellular carcinoma. 2 0 1
6203 16625598 Palliative biliary stents for obstructing pancreatic carcinoma. 1 0 1
6204 28485814 Partial nephrectomy versus radical nephrectomy for clinical localised renal masses. 2 0 1
6238 19370682 Combination formoterol and budesonide as maintenance and reliever therapy versus inhaled steroid maintenance for chronic asthma in adults and children. 1 0 1
6236 24343671 Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children. 1 0 1
5928 11279718 Ropinirole for levodopa-induced complications in Parkinson's disease. 1 0 1
6234 18425941 Ciclesonide versus placebo for chronic asthma in adults and children. 1 0 1
5930 22895930 Speech and language therapy versus placebo or no intervention for speech problems in Parkinson's disease. 1 0 1
5931 12917968 Therapies for depression in Parkinson's disease. 1 0 1
5932 26363646 Treadmill training for patients with Parkinson's disease. 1 0 1
5934 24497372 Interventions at caesarean section for reducing the risk of aspiration pneumonitis. 1 0 1
5935 25121931 Preoperative carbohydrate treatment for enhancing recovery after elective surgery. 1 0 1
5936 19821292 Antibiotics for community acquired pneumonia in adult outpatients. 1 0 1
5937 16856067 Antibiotics for community acquired pneumonia in children. 1 0 1
5942 14584011 Granulocyte colony stimulating factor (G-CSF) as an adjunct to antibiotics in the treatment of pneumonia in adults. 1 0 1
5947 15495133 Pneumococcal conjugate vaccines for preventing vaccine-type invasive pneumococcal disease and pneumonia with consolidation on x-ray in children under two years of age. 1 0 1
5950 29020436 Short-course versus long-course intravenous therapy with the same antibiotic for severe community-acquired pneumonia in children aged two months to 59 months. 1 0 1
5951 30188565 Short-course versus long-course therapy of the same antibiotic for community-acquired pneumonia in adolescent and adult outpatients. 1 0 1
6089 28815562 Treadmill training and body weight support for walking after stroke. 1 0 1
6090 20614431 Vasoactive drugs for acute stroke. 1 0 1
6091 18253980 Vinpocetine for acute ischaemic stroke. 1 0 1
6092 29156493 Virtual reality for stroke rehabilitation. 1 0 1
6230 24585221 Bronchial thermoplasty for moderate or severe persistent asthma in adults. 1 0 1
6231 16034941 Calorie controlled diet for chronic asthma. 1 0 1
6232 26014500 Chronic disease management programmes for adults with asthma. 1 0 1
6233 23450613 Ciclesonide versus other inhaled corticosteroids for chronic asthma in children. 1 0 1
6205 25620061 Percutaneous ethanol injection or percutaneous acetic acid injection for early hepatocellular carcinoma. 2 0 1
6206 23235660 Pre-operative chemoradiation for non-metastatic locally advanced rectal cancer. 1 0 1
6207 24357457 Radiofrequency (thermal) ablation versus no intervention or other interventions for hepatocellular carcinoma. 2 0 1
6208 15106188 Radiofrequency thermal ablation versus other interventions for hepatocellular carcinoma. 2 0 1
6292 27943237 Patient- and parent-initiated oral steroids for asthma exacerbations. 1 0 1
6293 28394084 Personalised asthma action plans for adults with asthma. 1 0 1
6295 22513914 Primary care based clinics for asthma. 1 0 1
6296 16437449 Psychological interventions for adults with asthma. 1 0 1
6286 26214266 Mepolizumab versus placebo for asthma. 1 0 1
6297 16235317 Psychological interventions for children with asthma. 1 0 1
6299 23744625 Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events. 1 0 1
6301 22419326 Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events. 1 0 1
6302 23543548 Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events. 1 0 1
6304 27087257 Remote versus face-to-face check-ups for asthma. 1 0 1
6305 24504983 Safety of regular formoterol or salmeterol in adults with asthma: an overview of Cochrane reviews. 1 0 1
6306 23076961 Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews. 1 0 1
6307 30687940 School-based self-management interventions for asthma in children and adolescents: a mixed methods systematic review. 1 0 1
6308 15106206 Selenium supplementation for asthma. 1 0 1
6309 28972652 Shared decision-making for people with asthma. 1 0 1
6298 20091646 Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events. 1 0 1
6284 26371536 Macrolides for chronic asthma. 1 0 1
6283 26301488 Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for adults with asthma. 1 0 1
6282 17636663 Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma. 1 0 1
6291 24414989 Omalizumab for asthma in adults and children. 1 0 1
6290 23450599 Nurse versus physician-led care for the management of asthma. 1 0 1
6289 16856028 Nedocromil sodium for chronic asthma in children. 1 0 1
6221 16625585 Anti-IgE for chronic asthma in adults and children. 1 0 1
6209 19160311 Radioiodine therapy for differentiated thyroid carcinoma with thyroglobulin positive and radioactive iodine negative metastases. 1 0 1
6210 11687105 Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus. 2 0 1
6227 24089311 Beta₂-agonists for exercise-induced asthma. 1 0 1
6211 20238346 Surgical management of localised renal cell carcinoma. 2 0 1
6213 21412886 Transarterial (chemo)embolisation for unresectable hepatocellular carcinoma. 2 0 1
6215 15106191 Addition of anti-leukotriene agents to inhaled corticosteroids for chronic asthma. 1 0 1
6219 19588447 Addition of long-acting beta-agonists to inhaled corticosteroids for chronic asthma in children. 1 0 1
6220 22972048 Alexander technique for chronic asthma. 1 0 1
6222 28933516 Anti-IL5 therapies for asthma. 1 0 1
6288 22696342 Monosodium glutamate avoidance for chronic asthma in adults and children. 1 0 1
6223 15266477 Anticholinergic agents for chronic asthma in adults. 1 0 1
6224 22513916 Anticholinergic therapy for acute asthma in children. 1 0 1
6225 21833925 Asthma challenges: The place of inhaled long-acting beta-agonists. 1 0 1
6212 23813393 Surgical resection versus liver transplant for patients with hepatocellular carcinoma. 2 0 1
6252 17054154 Heliox for nonintubated acute asthma patients. 1 0 1
6253 18254089 Herbal interventions for chronic asthma in adults and children. 1 0 1
6254 15106238 High dose versus low dose inhaled corticosteroid as initial starting dose for asthma in adults and children. 1 0 1
6287 19588394 Mono and multifaceted inhalant and/or food allergen reduction interventions for preventing asthma in children at high risk of developing asthma. 1 0 1
5929 11279719 Ropinirole versus bromocriptine for levodopa-induced complications in Parkinson's disease. 1 0 1
5927 10908539 Pramipexole versus bromocriptine for levodopa-induced complications in Parkinson's disease. 1 0 1
4306 23076941 Prophylactic antibiotics to reduce the risk of urinary tract infections after urodynamic studies. 1 0 1
5906 22071852 Anti-hypertensive drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies and clinical trials. 1 0 1
5908 10796755 Bromocriptine for levodopa-induced motor complications in Parkinson's disease. 1 0 1
5909 17943795 Bromocriptine/levodopa combined versus levodopa alone for early Parkinson's disease. 1 0 1
5910 11279720 Cabergoline for levodopa-induced complications in Parkinson's disease. 1 0 1
5911 11279721 Cabergoline versus bromocriptine for levodopa-induced complications in Parkinson's disease. 1 0 1
5912 15495119 Catechol-O-methyltransferase inhibitors for levodopa-induced complications in Parkinson's disease. 1 0 1
5913 22895931 Comparison of speech and language therapy techniques for speech problems in Parkinson's disease. 1 0 1
5904 12804468 Amantadine for dyskinesia in Parkinson's disease. 1 0 1
5914 24934384 Creatine for Parkinson's disease. 1 0 1
5892 25897825 Latrepirdine for Alzheimer's disease. 1 0 1
5890 12804498 Ibuprofen for Alzheimer's disease. 1 0 1
5869 12804444 Sympathectomy for neuropathic pain. 1 0 1
5870 26014160 Oral protein calorie supplementation for children with chronic disease. 1 0 1
5871 14974048 Adrenaline for prevention of morbidity and mortality in preterm infants with cardiovascular compromise. 1 0 1
5872 17636659 Anticonvulsants for preventing mortality and morbidity in full term newborns with perinatal asphyxia. 1 0 1
5873 12137696 Dopamine for prevention of morbidity and mortality in term newborn infants with suspected perinatal asphyxia. 1 0 1
5874 28358979 Pelvimetry for fetal cephalic presentations at or near term for deciding on mode of delivery. 1 0 1
5875 20091526 Dietary treatment for familial hypercholesterolaemia. 1 0 1
5876 22336816 Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease. 1 0 1
5877 29553158 Cholinergic medication for antipsychotic-induced tardive dyskinesia. 1 0 1
5907 12804486 Anticholinergics for symptomatic management of Parkinson's disease. 1 0 1
5905 12535476 Amantadine in Parkinson's disease. 1 0 1
5926 10908540 Pramipexole for levodopa-induced complications in Parkinson's disease. 1 0 1
5903 11279765 A comparison of physiotherapy techniques for patients with Parkinson's disease. 1 0 1
6057 30365156 Percutaneous vascular interventions versus intravenous thrombolytic treatment for acute ischaemic stroke. 1 0 1
6058 30887498 Pharmaceutical interventions for emotionalism after stroke. 1 0 1
6059 26544542 Pharmacological interventions for unilateral spatial neglect after stroke. 1 0 1
6060 27711973 Pharmacological interventions other than botulinum toxin for spasticity after stroke. 1 0 1
6062 24756870 Physical rehabilitation approaches for the recovery of function and mobility following stroke. 1 0 1
6051 24668137 Oral antiplatelet therapy for acute ischaemic stroke. 1 0 1
5983 22258987 Antibiotic therapy for preventing infections in patients with acute stroke. 1 0 1
5982 17253474 Amphetamines for improving recovery after stroke. 1 0 1
5981 27562656 Acupuncture for stroke rehabilitation. 1 0 1
5894 26513331 Montreal Cognitive Assessment for the diagnosis of Alzheimer's disease and other dementias. 2 0 1
5895 10796667 Nicotine for Alzheimer's disease. 1 0 1
5896 26393402 Rivastigmine for Alzheimer's disease. 1 0 1
5897 11687176 Statins for the prevention of Alzheimer's disease. 1 0 1
5898 11687043 Statins for the reduction of risk of Alzheimer's disease. 1 0 1
5899 10796644 Validation therapy for dementia. 1 0 1
5900 15106259 Velnacrine for Alzheimer's disease. 1 0 1
5901 18646084 Vitamin E for Alzheimer's disease and mild cognitive impairment. 1 0 1
5902 11034775 Vitamin E for Alzheimer's disease. 1 0 1
5893 18254079 Metal protein attenuating compounds for the treatment of Alzheimer's disease. 1 0 1
5891 12076498 Indomethacin for the treatment of Alzheimer's disease patients. 1 0 1
5878 12137608 Cholinergic medication for neuroleptic-induced tardive dyskinesia. 1 0 1
5881 30480324 Community-based supplementary feeding for food insecure, vulnerable and malnourished populations - an overview of systematic reviews. 2 0 1
5882 12076471 D-cycloserine for Alzheimer's disease. 1 0 1
5971 15495092 Progressive resistive exercise interventions for adults living with HIV/AIDS. 1 0 1
5972 21678344 Provider training and experience for people living with HIV/AIDS. 1 0 1
5973 16856042 Setting and organization of care for persons living with HIV/AIDS. 1 0 1
5974 16625606 Stavudine, lamivudine and nevirapine combination therapy for treatment of HIV infection and AIDS in adults. 1 0 1
5975 27364851 Technological aids for the rehabilitation of memory and executive functioning in children and adolescents with acquired brain injury. 1 0 1
5977 19588417 Acanthopanax for acute ischaemic stroke. 1 0 1
5978 30380586 Action observation for upper limb rehabilitation after stroke. 1 0 1
5979 30051462 Activity monitors for increasing physical activity in adult stroke survivors. 1 0 1
5980 29607495 Acupuncture for acute stroke. 1 0 1
5970 25738963 Optical reading aids for children and young people with low vision. 1 0 1
5958 19821399 Interventions for educating traditional healers about STD and HIV medicine. 1 0 1
5957 29465747 Antibiotics for treating gonorrhoea in pregnancy. 2 0 1
5956 18254124 Abstinence-plus programs for HIV infection prevention in high-income countries. 1 0 1
5919 19821381 Monoamine oxidase B inhibitors versus other dopaminergic agents in early Parkinson's disease. 1 0 1
5921 10796704 Pergolide for levodopa-induced complications in Parkinson's disease. 1 0 1
5922 10796705 Pergolide versus bromocriptine for levodopa-induced motor complications in Parkinson's disease. 1 0 1
5923 24936965 Physiotherapy for Parkinson's disease: a comparison of techniques. 1 0 1
5924 11687029 Physiotherapy for patients with Parkinson's Disease: a comparison of techniques. 1 0 1
5925 24018704 Physiotherapy versus placebo or no intervention in Parkinson's disease. 1 0 1
5969 20091636 Massage therapy for people with HIV/AIDS. 1 0 1
5959 10796106 Interventions for treating genital chlamydia trachomatis infection in pregnancy. 1 0 1
5968 27292836 Interventions for tobacco use cessation in people living with HIV and AIDS. 1 0 1
5916 10796801 Lisuride for levodopa-induced complications in Parkinson's disease. 1 0 1
5883 10796526 Dehydroepiandrosterone (DHEA) supplementation for cognition and well-being. 1 0 1
5884 11405958 Dehydroepiandrosterone (DHEA) supplementation for cognitive function . 1 0 1
5885 11034704 Donepezil for mild and moderate Alzheimer's disease. 1 0 1
5886 16856114 Donepezil for mild cognitive impairment. 1 0 1
5887 16437436 Galantamine for Alzheimer's disease and mild cognitive impairment. 1 0 1
5888 15495017 Galantamine for Alzheimer's disease. 1 0 1
5889 23235666 Huperzine A for mild cognitive impairment. 1 0 1
5880 16437529 Clioquinol for the treatment of Alzheimer's Disease. 1 0 1
5917 10796800 Lisuride versus bromocriptine for levodopa-induced complications in Parkinson's disease. 1 0 1
5967 19370650 Interventions for improving the psychosocial well-being of children affected by HIV and AIDS. 1 0 1
5918 16034956 Monoamine oxidase B inhibitors for early Parkinson's disease. 1 0 1
5960 21412869 Population-based biomedical sexually transmitted infection control interventions for reducing HIV infection. 2 0 1
5961 21735392 Strategies for integrating primary health services in low- and middle-income countries at the point of delivery. 2 0 1
5962 20687068 Aerobic exercise interventions for adults living with HIV/AIDS. 1 0 1
5963 11279729 Aerobic exercise interventions for people with HIV/AIDS. 1 0 1
5964 24482186 Amplification with hearing aids for patients with tinnitus and co-existing hearing loss. 1 0 1
5965 28944461 Hearing aids for mild to moderate hearing loss in adults. 1 0 1
5966 22972150 Integration of HIV/AIDS services with maternal, neonatal and child health, nutrition, and family planning services. 1 0 1
6255 16437434 Holding chambers versus nebulisers for inhaled steroids in chronic asthma. 1 0 1
6256 27486836 Home telemonitoring and remote feedback between clinic visits for asthma. 1 0 1
6257 21975783 Home-based educational interventions for children with asthma. 1 0 1
6168 24817558 Inhaled hyperosmolar agents for bronchiectasis. 1 0 1
6171 26576499 Interventions for enhancing adherence to treatment in adults with bronchiectasis. 1 0 1
6199 25354795 Interventions for dysphagia in oesophageal cancer. 1 0 1
5001 20238315 Intravenous immunoglobulin for suspected or subsequently proven infection in neonates. 1 0 1
5227 16856078 Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis. 3 0 1
4322 20464760 Embolisation therapy for pulmonary arteriovenous malformations. 1 0 1
4243 23633317 Prevention and treatment of postpartum hypertension. 3 0 1
4244 17054277 Progesterone for preventing pre-eclampsia and its complications. 2 0 1
4245 22696380 Pulmonary artery flow catheters for directing management in pre-eclampsia. 2 0 1
4246 26039815 Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes. 2 0 1
4247 16625530 Pyridoxine (vitamin B6) supplementation in pregnancy. 2 0 1
4248 10796269 Reduced salt intake compared to normal dietary salt, or high intake, in pregnancy. 2 0 1
4250 28602020 Techniques of monitoring blood glucose during pregnancy for women with pre-existing diabetes. 2 0 1
4251 21735406 Tight control of mild-moderate pre-existing or non-proteinuric gestational hypertension. 3 0 1
4252 20824875 Utero-placental Doppler ultrasound for improving pregnancy outcome. 3 0 1
4253 15846697 Vitamin supplementation for preventing miscarriage. 2 0 1
4254 23633329 Herbal preparations for uterine fibroids. 1 0 1
4255 17943846 Selective estrogen receptor modulators (SERMs) for uterine leiomyomas. 1 0 1
4256 28444736 Selective progesterone receptor modulators (SPRMs) for uterine fibroids. 1 0 1
4257 28284020 Frenotomy for tongue-tie in newborn infants. 1 0 1
6169 26816298 Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis. 1 0 1
6167 29766487 Inhaled corticosteroids for bronchiectasis. 1 0 1
6259 25517002 How should we describe worsening asthma in Cochrane reviews, and does it matter? 1 0 1
6166 30184243 Head-to-head trials of antibiotics for bronchiectasis. 1 0 1
6174 24789119 Mucolytics for bronchiectasis. 1 0 1
6173 11687145 Long-acting beta-2-agonists for bronchiectasis. 1 0 1
6172 11034744 Leukotriene receptor antagonists for non-cystic fibrosis bronchiectasis. 1 0 1
6148 23152218 Management of sexual dysfunction due to antipsychotic drug therapy. 1 0 1
6149 22161405 Mirtazapine versus other antidepressive agents for depression. 1 0 1
6150 17443515 Pre-operative radiotherapy and curative surgery for the management of localized rectal carcinoma. 2 0 1
6151 30284239 Preoperative radiotherapy and curative surgery for the management of localised rectal carcinoma. 2 0 1
6152 10796657 Sertindole for schizophrenia. 1 0 1
6153 23728643 Strategies for managing sexual dysfunction induced by antidepressant medication. 1 0 1
6154 29502352 Surgery for women with posterior compartment prolapse. 2 0 1
6155 12917938 Interventions for improving communication with children and adolescents about their cancer. 1 0 1
6157 22895969 Genital ulcer disease treatment for reducing sexual acquisition of HIV. 2 0 1
6158 29226307 Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. 1 0 1
6159 11687030 Domiciliary oxygen for interstitial lung disease. 2 0 1
6161 16235384 Antibiotics for prolonged moist cough in children. 1 0 1
6162 11687147 Anticholinergic therapy for bronchiectasis. 1 0 1
6163 27405706 Codeine versus placebo for chronic cough in children. 1 0 1
6164 24913725 Combination inhaled corticosteroids and long-acting beta2-agonists for children and adults with bronchiectasis. 1 0 1
6165 29860722 Continuous versus intermittent antibiotics for bronchiectasis. 1 0 1
4258 11405986 Antibiotic prophylaxis for intrauterine contraceptive device insertion. 2 0 1
4260 20556773 Copper containing intra-uterine devices versus depot progestogens for contraception. 1 0 1
4261 10796820 Immediate post-abortal insertion of intrauterine devices. 1 0 1
4262 25101364 Immediate postabortal insertion of intrauterine devices. 1 0 1
4237 30480773 Omega-3 fatty acid addition during pregnancy. 3 0 1
4238 11034777 Oral beta-blockers for mild to moderate hypertension during pregnancy. 1 0 1
4240 29058762 Planned caesarean section versus planned vaginal birth for severe pre-eclampsia. 2 0 1
4213 10796090 Anticonvulsants for women with pre-eclampsia. 2 0 1
4265 26114777 Chelation for autism spectrum disorder (ASD). 2 0 1
4267 25758061 Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low-birth-weight infants. 2 0 1
4291 15744796 Psychosocial treatment for opiate abuse and dependence. 2 0 1
4292 15674937 Cyclosporine A for induction of remission in severe ulcerative colitis. 4 0 1
4293 10796613 Pharmacotherapy for inducing and maintaining remission in pouchitis. 2 0 1
4295 12137628 Antibiotic duration for treating uncomplicated, symptomatic lower urinary tract infections in elderly women. 1 0 1
4296 16034973 Antibiotic policies for short-term catheter bladder drainage in adults. 2 0 1
4297 23824735 Antibiotic prophylaxis for short-term catheter bladder drainage in adults. 2 0 1
4298 21563156 Antibiotic prophylaxis for transrectal prostate biopsy. 2 0 1
4299 29390169 Antibiotics for asymptomatic bacteriuria in kidney transplant recipients. 1 0 1
4301 22895956 Antibiotics for treating lower urinary tract infection in children. 1 0 1
4302 30789676 Antimicrobial agents for preventing urinary tract infections in adults undergoing cystoscopy. 1 0 1
4303 20824868 Different antibiotic regimens for treating asymptomatic bacteriuria in pregnancy. 2 0 1
4304 22336827 Interventions for covert bacteriuria in children. 1 0 1
4305 23076896 Methenamine hippurate for preventing urinary tract infections. 1 0 1
4236 10796157 Nutritional advice in pregnancy. 2 0 1
4235 16856006 Marine oil, and other prostaglandin precursor, supplementation for pregnancy uncomplicated by pre-eclampsia or intrauterine growth restriction. 3 0 1
4231 17253491 Low-dose dopamine for women with severe pre-eclampsia. 2 0 1
4218 21975761 Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes. 2 0 1
4263 15674886 Grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children. 1 0 1
4242 10796166 Plasma volume expansion for suspected impaired fetal growth. 2 0 1
4264 20614467 Surgery for tympanic membrane retraction pockets. 1 0 1
4241 28106904 Planned early delivery versus expectant management for hypertensive disorders from 34 weeks gestation to term. 4 0 1
4239 29870574 Parenteral opioids for maternal pain management in labour. 2 0 1
4214 18254042 Antioxidants for preventing pre-eclampsia. 2 0 1
4215 10796208 Antiplatelet agents for preventing and treating pre-eclampsia. 2 0 1
4217 24995856 Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia. 5 0 1
4219 16625625 Chinese herbal medicine for the treatment of pre-eclampsia. 2 0 1
4229 20614463 Interventions for clinical and subclinical hypothyroidism in pregnancy. 6 0 1
4220 28156005 Different insulin types and regimens for pregnant women with pre-existing diabetes. 2 0 1
4221 27142841 Different intensities of glycaemic control for pregnant women with pre-existing diabetes. 2 0 1
4222 17253507 Diuretics for preventing pre-eclampsia. 2 0 1
4223 23900968 Drugs for treatment of very high blood pressure during pregnancy. 1 0 1
4224 14583907 Energy and protein intake in pregnancy. 2 0 1
4225 10796119 Energy/protein restriction for high weight-for-height or weight gain during pregnancy. 2 0 1
4227 16856110 Garlic for preventing pre-eclampsia and its complications. 2 0 1
4228 26671418 Incentives for increasing prenatal care use by women in order to improve maternal and neonatal outcomes. 2 0 1
6188 22419298 Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer. 1 0 1
6197 15674877 Immunotherapy for advanced renal cell cancer. 2 0 1
6196 28415140 Imaging modalities for characterising focal pancreatic lesions. 2 0 1
6143 25058164 Topical lidocaine for neuropathic pain in adults. 1 0 1
6120 24114324 Optimal time for initiating antiretroviral therapy (ART) in HIV-infected, treatment-naive children aged 2 to 5 years old. 1 0 1
6121 20238364 Optimal time for initiation of antiretroviral therapy in asymptomatic, HIV-infected, treatment-naive adults. 1 0 1
6122 22592714 Patient education and counselling for promoting adherence to treatment for tuberculosis. 1 0 1
6123 22336833 Paying for performance to improve the delivery of health interventions in low- and middle-income countries . 1 0 1
6124 10796641 Regimens of less than six months for treating tuberculosis. 1 0 1
6125 18843723 Reminder systems and late patient tracers in the diagnosis and management of tuberculosis. 1 0 1
6128 27581996 Six months therapy for tuberculous meningitis. 2 0 1
6129 26777994 Smoking cessation interventions for pulmonary tuberculosis treatment outcomes. 1 0 1
6118 12535403 Mycobacterium vaccae immunotherapy for treating tuberculosis. 1 0 1
6130 10796669 Steroids for treating tuberculous pleurisy. 2 0 1
6132 25353401 The diagnostic accuracy of the GenoType(®) MTBDRsl assay for the detection of resistance to second-line anti-tuberculosis drugs. 1 0 1
6133 23440826 Treating BCG-induced disease in children. 1 0 1
6134 20091503 Treatment of latent tuberculosis infection in HIV infected persons. 1 0 1
6135 24448973 Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults. 1 0 1
6136 30293234 Occupational therapy delivered by specialists versus non-specialists for people with schizophrenia. 2 0 1
6138 25062018 Botulinum toxin for myofascial pain syndromes in adults. 1 0 1
6139 26497573 Safety of topical corticosteroids in pregnancy. 1 0 1
6141 24297506 Non-antiepileptic drugs for trigeminal neuralgia. 1 0 1
6142 25569864 Nortriptyline for neuropathic pain in adults. 1 0 1
6119 27355911 Nutritional supplements for people being treated for active tuberculosis. 1 0 1
6198 28504837 Immunotherapy for metastatic renal cell carcinoma. 2 0 1
6200 20091639 Lymphadenectomy for the management of endometrial cancer. 1 0 1
6268 30521673 Inhaled steroids with and without regular salmeterol for asthma: serious adverse events. 1 0 1
6260 27272563 Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children. 1 0 1
6261 20464742 Indigenous healthcare worker involvement for Indigenous adults and children with asthma. 1 0 1
6262 15674896 Inhaled beclomethasone versus placebo for chronic asthma. 1 0 1
6263 25030198 Inhaled corticosteroids in children with persistent asthma: effects on growth. 1 0 1
6264 16625584 Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma. 1 0 1
6265 29182799 Inhaled magnesium sulfate in the treatment of acute asthma. 1 0 1
6266 18843630 Inhaled sodium cromoglycate for asthma in children. 1 0 1
6267 23235590 Inhaled steroids for acute asthma following emergency department discharge. 1 0 1
6270 26197430 Intermittent inhaled corticosteroid therapy versus placebo for persistent asthma in children and adults. 1 0 1
6311 28146601 Stepping down the dose of inhaled corticosteroids for adults with asthma. 1 0 1
6271 19370563 Interventions for educating children who are at risk of asthma-related emergency department attendance. 1 0 1
6272 28417456 Interventions to improve adherence to inhaled steroids for asthma. 1 0 1
6273 28288272 Interventions to improve inhaler technique for people with asthma. 1 0 1
6274 15846615 Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators. 1 0 1
6275 23235686 Intravenous beta(2)-agonists versus intravenous aminophylline for acute asthma. 1 0 1
6279 14973969 Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children. 1 0 1
6281 16235393 Long-acting beta2-agonists as an inhaled corticosteroid-sparing agent for chronic asthma in adults and children. 1 0 1
6201 10796754 Neoadjuvant and adjuvant therapy for operable hepatocellular carcinoma. 2 0 1
6131 29910691 Symptom screening for active tuberculosis in pregnant women living with HIV. 1 0 1
6117 22258976 Material incentives and enablers in the management of tuberculosis. 1 0 1
6195 28267205 External beam radiotherapy for unresectable hepatocellular carcinoma. 2 0 1
6115 27163343 Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in HIV-positive adults. 1 0 1
6146 23737033 Hormone therapy for sexual function in perimenopausal and postmenopausal women. 1 0 1
6147 12535412 Interventions for vaginismus. 1 0 1
6176 29926473 Nurse-led versus doctor-led care for bronchiectasis. 1 0 1
6177 11279764 Oral methyl-xanthines for bronchiectasis. 1 0 1
6178 17943909 Oral non steroid anti-inflammatories for children and adults with bronchiectasis. 1 0 1
6179 11687146 Oral steroids for bronchiectasis (stable and acute exacerbations). 1 0 1
6180 12137647 Physical training for bronchiectasis. 1 0 1
6181 28952156 Positive expiratory pressure therapy versus other airway clearance techniques for bronchiectasis. 1 0 1
6182 17443506 Prolonged antibiotics for purulent bronchiectasis in children and adults. 1 0 1
6183 14583934 Prolonged antibiotics for purulent bronchiectasis. 1 0 1
6184 12917973 Short acting beta-2 agonists for bronchiectasis. 1 0 1
6175 12918011 Nurse specialist care for bronchiectasis. 1 0 1
6185 21678381 Short courses of antibiotics for children and adults with bronchiectasis. 1 0 1
6189 17054200 Chemotherapy as an adjunct to radiotherapy in locally advanced nasopharyngeal carcinoma. 1 0 1
6190 20091593 Combined use of hyperthermia and radiation therapy for treating locally advanced cervical carcinoma. 1 0 1
6191 20238344 Combined use of hyperthermia and radiation therapy for treating locally advanced cervix carcinoma. 1 0 1
6192 14974044 Concomitant hydroxyurea plus radiotherapy versus radiotherapy for carcinoma of the uterine cervix. 1 0 1
6193 20464746 Covering ileo- or colostomy in anterior resection for rectal carcinoma. 1 0 1
6194 19821432 Cryotherapy for hepatocellular carcinoma. 2 0 1
6145 22972065 Antidepressants for patients with tinnitus. 1 0 1
6105 23744519 Fluoroquinolones for treating tuberculosis (presumed drug-sensitive). 1 0 1
6114 10796642 Isoniazid for preventing tuberculosis in non-HIV infected persons. 1 0 1
6103 28891235 Financial arrangements for health systems in low-income countries: an overview of systematic reviews. 1 0 1
6093 22972051 Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed arterial origin. 1 0 1
6094 21249701 Water-based exercises for improving activities of daily living after stroke. 1 0 1
6095 29220541 Yoga for stroke rehabilitation. 1 0 1
6096 21901723 Active case finding in contacts of people with tuberculosis. 1 0 1
6097 25387839 Adjunctive steroid therapy for managing pulmonary tuberculosis. 1 0 1
6098 27806184 Antifibrinolytic therapy to reduce haemoptysis from any cause. 1 0 1
6101 11034676 Drugs for preventing tuberculosis in HIV infected persons. 1 0 1
6102 16625639 Drugs for preventing tuberculosis in people at risk of multiple-drug-resistant pulmonary tuberculosis. 1 0 1
6116 16625582 Low level laser therapy for treating tuberculosis. 1 0 1
6113 28850172 Isoniazid for preventing tuberculosis in HIV-infected children. 1 0 1
6104 27186634 Fixed-dose combinations of drugs versus single-drug formulations for treating pulmonary tuberculosis. 1 0 1
6106 18254061 Fluoroquinolones for treating tuberculosis. 1 0 1
6107 11687088 Fully intermittent dosing with drugs for treating tuberculosis in adults. 1 0 1
6108 11034692 Fully intermittent dosing with drugs for tuberculosis. 1 0 1
6109 26333525 Incentives and enablers to improve adherence in tuberculosis. 1 0 1
6110 24470141 Intermittent versus daily therapy for treating tuberculosis in children. 1 0 1
6111 11034666 Interventions for promoting adherence to tuberculosis management. 1 0 1
6112 29182800 Interventions to increase tuberculosis case detection at primary healthcare or community-level services. 1 0 1
3875 22895962 Nutritional interventions for liver-transplanted patients. 1 0 1
3878 22071855 Probiotics for patients with hepatic encephalopathy. 3 0 1
6055 26329401 Parenteral fluid regimens for improving functional outcome in people with acute stroke. 1 0 1
4847 11279790 Rescue high frequency oscillatory ventilation vs conventional ventilation for infants with severe pulmonary dysfunction born at or near term. 1 0 1
4778 30480772 Fecal transplantation for treatment of inflammatory bowel disease. 5 0 1
4834 23450605 Hydralazine in infants with persistent hypoxemic respiratory failure. 2 0 1
4846 26998745 Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in newborn infants. 1 0 1
4845 12535389 Prophylactic methylxanthines for extubation in preterm infants. 2 0 1
4780 30699470 General health checks in adults for reducing morbidity and mortality from disease. 1 0 1
4844 10796303 Prophylactic methylxanthine for extubation in preterm infants. 2 0 1
4781 29044482 Hematopoietic stem cell transplantation for Gaucher disease. 1 0 1
4782 28731502 Histologic scoring indices for evaluation of disease activity in Crohn's disease. 3 0 1
4783 30869157 Interventions to support return to work for people with coronary heart disease. 1 0 1
4779 28085995 Fibrin glue for pilonidal sinus disease. 1 0 1
4774 27501379 Endoscopic scoring indices for evaluation of disease activity in Crohn's disease. 3 0 1
4833 19588337 High frequency oscillatory ventilation versus conventional ventilation for infants with severe pulmonary dysfunction born at or near term. 1 0 1
4794 28613408 Pre-admission antibiotics for suspected cases of meningococcal disease. 2 0 1
4816 24919591 Positive end-expiratory pressure (PEEP) during anaesthesia for prevention of mortality and postoperative pulmonary complications. 1 0 1
4819 24659357 Terbutaline pump maintenance therapy after threatened preterm labour for reducing adverse neonatal outcomes. 1 0 1
4815 10796391 Nasal versus oral intubation for mechanical ventilation of newborn infants. 1 0 1
4814 19588380 Incentive spirometry for prevention of postoperative pulmonary complications in upper abdominal surgery. 1 0 1
4820 24729285 Indwelling bladder catheterisation as part of intraoperative and postoperative care for caesarean section. 1 0 1
4813 17636760 Incentive spirometry for preventing pulmonary complications after coronary artery bypass graft. 1 0 1
4777 29155436 Enzyme replacement therapy for infantile-onset Pompe disease. 2 0 1
4848 26558953 Immunotherapy (oral and sublingual) for food allergy to fruits. 2 0 1
4949 19160214 Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood. 1 0 1
4532 24505016 Mycophenolate mofetil for relapsing-remitting multiple sclerosis. 2 0 1
4729 21491406 Treatment of obstructive sleep apnoea for chronic cough in children. 1 0 1
4793 29727467 Pharmacological interventions for apathy in Alzheimer's disease. 2 0 1
4792 30036453 Pembrolizumab monotherapy versus chemotherapy for treatment of advanced urothelial carcinoma with disease progression during or following platinum-containing chemotherapy. A Cochrane Rapid Review. 2 0 1
4791 28658719 Patient education in the management of coronary heart disease. 1 0 1
4835 24510642 Incentive spirometry for prevention of postoperative pulmonary complications in upper abdominal surgery. 1 0 1
4790 27681657 Oral 5-aminosalicylic acid for maintenance of medically-induced remission in Crohn's disease. 2 0 1
4789 27873322 Non-medical prescribing versus medical prescribing for acute and chronic disease management in primary and secondary care. 1 0 1
4837 12535438 Inhaled nitric oxide for acute hypoxemic respiratory failure in children and adults. 1 0 1
4788 30697701 Mesenchymal stromal cells as treatment or prophylaxis for acute or chronic graft-versus-host disease in haematopoietic stem cell transplant (HSCT) recipients with a haematological condition. 1 0 1
4838 15495117 Long versus short inspiratory times in neonates receiving mechanical ventilation. 4 0 1
4839 28146296 Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation. 1 0 1
4787 29658630 Lumbar sympathectomy versus prostanoids for critical limb ischaemia due to non-reconstructable peripheral arterial disease. 1 0 1
4786 27959471 Lumbar sympathectomy techniques for critical lower limb ischaemia due to non-reconstructable peripheral arterial disease. 1 0 1
4841 23152223 Perioperative increase in global blood flow to explicit defined goals and outcomes following surgery. 1 0 1
4842 24865303 Pressure support versus T-tube for weaning from mechanical ventilation in adults. 1 0 1
4843 10908519 Prophylactic doxapram for the prevention of morbidity and mortality in preterm infants undergoing endotracheal extubation. 1 0 1
4785 29607497 Low dose naltrexone for induction of remission in Crohn's disease. 2 0 1
4784 29199768 Invasive versus non-invasive ventilation for acute respiratory failure in neuromuscular disease and chest wall disorders. 4 0 1
4775 29338066 Endoscopic scoring indices for evaluation of disease activity in ulcerative colitis. 3 0 1
4812 18646156 Chest physiotherapy for reducing respiratory morbidity in infants requiring ventilatory support. 1 0 1
4811 12076390 Chest physiotherapy for preventing morbidity in babies being extubated from mechanical ventilation. 2 0 1
4810 19160243 Short versus standard duration antibiotic therapy for acute streptococcal pharyngitis in children. 2 0 1
4809 12137650 Penicillin for secondary prevention of rheumatic fever. 1 0 1
4773 28052185 Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight preterm neonates. 1 0 1
4772 30136733 Drugs for treating Buruli ulcer (Mycobacterium ulcerans disease). 2 0 1
4771 30736095 Dietary interventions for induction and maintenance of remission in inflammatory bowel disease. 5 0 1
4751 23925699 Autologous hematopoietic stem cell transplantation following high dose chemotherapy for non-rhabdomyosarcoma soft tissue sarcomas. 1 0 1
4869 30589445 Sound therapy (using amplification devices and/or sound generators) for tinnitus. 1 0 1
4750 22696376 Colony-stimulating factors for prevention and treatment of infectious complications in patients with acute myelogenous leukemia. 2 0 1
4870 25854331 Telerehabilitation for persons with multiple sclerosis. 2 0 1
4871 25879088 Adjunctive hyperbaric oxygen for necrotizing fasciitis. 2 0 1
4749 30408162 Perioperative alcohol cessation intervention for postoperative complications. 1 0 1
4748 25726920 Motivational interviewing for smoking cessation. 1 0 1
4747 29761479 Antidepressants for insomnia in adults. 2 0 1
4874 24683051 Alpha2-adrenergic agonists for the management of opioid withdrawal. 1 0 1
4746 20238337 Anticonvulsants for alcohol withdrawal. 2 0 1
4875 16034964 Benzodiazepines for alcohol withdrawal. 1 0 1
4745 23857592 Psychosocial interventions for patients with head and neck cancer. 1 0 1
4744 21491393 Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy. 3 0 1
4743 22513964 Exercise interventions for shoulder dysfunction in patients treated for head and neck cancer. 1 0 1
4742 23440820 Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy. 1 0 1
4741 23450590 Dental extractions prior to radiotherapy to the jaws for reducing post-radiotherapy dental complications. 1 0 1
4800 30570742 Treatment of epilepsy for people with Alzheimer's disease. 3 0 1
4825 12804447 Prostacyclin for pulmonary hypertension. 4 0 1
4826 19821356 Oral potassium iodide for the treatment of sporotrichosis. 1 0 1
4796 28452408 Psychological interventions for coronary heart disease. 2 0 1
4808 26017576 Anti-inflammatory treatment for carditis in acute rheumatic fever. 1 0 1
4807 27149547 Psychosocial interventions for cannabis use disorder. 1 0 1
4822 25855311 Medical interventions for fungal keratitis. 2 0 1
4805 23440817 Pharmacological therapies for maintenance treatments of opium dependence. 1 0 1
4804 28211045 Walk-in clinics versus physician offices and emergency rooms for urgent care and chronic disease management. 1 0 1
4824 27364644 Antibiotics for treating septic abortion. 2 0 1
4803 28000926 Virtual reality for rehabilitation in Parkinson's disease. 2 0 1
4795 30156270 Primary antifungal prophylaxis for cryptococcal disease in HIV-positive people. 1 0 1
4830 26731032 Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery. 1 0 1
4827 26858174 Antithrombin III for critically ill patients. 2 0 1
4797 29185627 Strategies for enhancing the implementation of school-based policies or practices targeting risk factors for chronic disease. 2 0 1
4829 11279726 Corticosteroids for acute severe asthma in hospitalised patients. 1 0 1
4798 27425786 Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease. 2 0 1
4831 18646070 Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants. 2 0 1
4799 29665617 Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in people with coronary artery disease. 2 0 1
4801 28440858 Treatment with disease-modifying drugs for people with a first clinical attack suggestive of multiple sclerosis. 2 0 1
4802 30520517 Updating guidance for preventing and treating cryptococcal disease: how evidence and decisions interface. 1 0 1
4828 23966133 Combined inhaled anticholinergics and short-acting beta2-agonists for initial treatment of acute asthma in children. 2 0 1
4882 23990373 Endometrial resection and ablation techniques for heavy menstrual bleeding. 1 0 1
4658 25150465 Monitoring of stimulated cycles in assisted reproduction (IVF and ICSI). 1 0 1
4718 23450606 Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults. 2 0 1
4647 23152261 Clomiphene citrate in combination with gonadotropins for controlled ovarian stimulation in women undergoing in vitro fertilization. 1 0 1
4645 19160253 Combined psychotherapy plus benzodiazepines for panic disorder. 1 0 1
4644 26250102 Interventions for idiopathic intracranial hypertension. 2 0 1
4932 24604627 Psychological therapies for thalassaemia. 1 0 1
4643 16034888 Short term benefits for laparoscopic colorectal resection. 2 0 1
4933 19160318 Cholecystectomy for suspected gallbladder dyskinesia. 1 0 1
4934 11686993 Sphincterotomy for biliary sphincter of Oddi dysfunction. 2 0 1
4642 12137699 Early compared with delayed oral fluids and food after caesarean section. 1 0 1
4641 29619778 Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery. 1 0 1
4640 25914904 Chewing gum for postoperative recovery of gastrointestinal function. 1 0 1
4639 27747876 Chewing gum for enhancing early recovery of bowel function after caesarean section. 2 0 1
4638 28462518 Alvimopan for recovery of bowel function after radical cystectomy. 1 0 1
4935 30582609 Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment. 2 0 1
4936 21154367 Interventions for the treatment of oral cavity and oropharyngeal cancer: radiotherapy. 1 0 1
4937 26171910 Negative pressure wound therapy for treating leg ulcers. 1 0 1
4938 26662471 Ascorbic acid for the treatment of Charcot-Marie-Tooth disease. 4 0 1
4629 11869671 Acupuncture for lateral elbow pain. 1 0 1
4948 21735420 Antidepressants for the treatment of abdominal pain-related functional gastrointestinal disorders in children and adolescents. 1 0 1
4631 11406011 Orthotic devices for tennis elbow. 1 0 1
4947 10796770 Antidepressants for depression in people with physical illness. 2 0 1
4646 12137659 "Coasting" (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome. 1 0 1
4676 20927754 Early versus late pre-intensive care unit admission broad spectrum antibiotics for severe sepsis in adults. 1 0 1
4663 26899415 Anaesthesia for hip fracture surgery in adults. 1 0 1
4677 28099689 Effectiveness and safety of procalcitonin evaluation for reducing mortality in adults with sepsis, severe sepsis or septic shock. 1 0 1
4716 16855994 Humidified air inhalation for treating croup. 3 0 1
4715 20166089 Heliox for croup in children. 1 0 1
4891 18425862 Cervical insemination versus intra-uterine insemination of donor sperm for subfertility. 1 0 1
4898 10796189 Interventions for treating bacterial vaginosis in pregnancy. 1 0 1
4705 15846751 Addition of inhaled long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults. 2 0 1
4897 23440777 Antibiotics for treating bacterial vaginosis in pregnancy. 2 0 1
4708 22592685 Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. 2 0 1
4709 22161385 Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children. 2 0 1
4710 16235409 Combination of inhaled long-acting beta2-agonists and inhaled steroids versus higher dose of inhaled steroids in children and adults with persistent asthma. 2 0 1
4702 10796398 Prazosin for Raynaud's phenomenon in progressive systemic sclerosis. 3 0 1
4895 26092137 Antibiotic prophylaxis during the second and third trimester to reduce adverse pregnancy outcomes and morbidity. 3 0 1
4711 14583926 Continuous versus intermittent beta-agonists in the treatment of acute asthma. 1 0 1
4712 19588321 Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. 1 0 1
4713 24442817 Dexmedetomidine for the management of awake fibreoptic intubation. 1 0 1
4714 26258959 Early versus late removal of the laryngeal mask airway (LMA) for general anaesthesia. 2 0 1
4893 24683020 Vasectomy occlusion techniques for male sterilization. 1 0 1
4892 22419294 Steroid hormones for contraception in men. 1 0 1
4894 17054287 Calcimimetics for secondary hyperparathyroidism in chronic kidney disease patients. 3 0 1
4678 22419295 Human recombinant activated protein C for severe sepsis. 1 0 1
4632 11869609 Orthotic devices for the treatment of tennis elbow. 1 0 1
4633 11869669 Shock wave therapy for lateral elbow pain. 1 0 1
4648 17636707 Embryo freezing for preventing ovarian hyperstimulation syndrome. 1 0 1
4946 11034712 Antidepressants for depression in medical illness. 2 0 1
4674 14973984 Corticosteroids for treating severe sepsis and septic shock. 1 0 1
4675 23543557 De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock. 1 0 1
4923 15495063 Reduced osmolarity oral rehydration solution for treating cholera. 3 0 1
4727 11406043 Spinal immobilisation for trauma patients. 1 0 1
4927 24226646 Blood transfusion for preventing primary and secondary stroke in people with sickle cell disease. 1 0 1
4929 28809446 Deferasirox for managing iron overload in people with thalassaemia. 1 0 1
4652 21249699 Gonadotropin-releasing hormone agonist versus HCG for oocyte triggering in antagonist assisted reproductive technology cycles. 1 0 1
4653 25358904 Gonadotropin-releasing hormone agonist versus HCG for oocyte triggering in antagonist-assisted reproductive technology. 1 0 1
4654 26583517 In vitro fertilisation for unexplained subfertility. 1 0 1
4931 22071798 Low versus high haemoglobin concentration threshold for blood transfusion for preventing morbidity and mortality in very low birth weight infants. 1 0 1
4655 12076404 Intra-venous albumin for preventing severe ovarian hyperstimulation syndrome. 1 0 1
4656 26148507 Luteal phase support for assisted reproduction cycles. 1 0 1
4928 26436602 Comparison of a restrictive versus liberal red cell transfusion policy for patients with myelodysplasia, aplastic anaemia, and other congenital bone marrow failure disorders. 2 0 1
4657 15266541 Luteal phase support in assisted reproduction cycles. 1 0 1
4659 23990351 Natural cycle in vitro fertilisation (IVF) for subfertile couples. 1 0 1
4660 12137671 Oral versus injectable ovulation induction agents for unexplained subfertility. 1 0 1
4661 10796711 Timed intercourse versus intra-uterine insemination with or without ovarian hyperstimulation for subfertility in men. 1 0 1
4930 28921500 Growth hormone therapy for people with thalassaemia. 1 0 1
4662 25386666 Aerobic physical exercise for adult patients with haematological malignancies. 1 0 1
4922 15266548 TIPS versus paracentesis for cirrhotic patients with refractory ascites. 1 0 1
4672 30321906 Very early versus delayed mobilisation after stroke. 2 0 1
4817 20824871 Positive end-expiratory pressure (PEEP) during anaesthesia for the prevention of mortality and postoperative pulmonary complications. 2 0 1
4650 10796488 Gonadotrophin-releasing hormone analogue as an adjunct to gonadotropin therapy for clomiphene-resistant polycystic ovarian syndrome. 1 0 1
4945 17054142 Interventions for treating oral leukoplakia. 2 0 1
4635 28334427 Capnography versus standard monitoring for emergency department procedural sedation and analgesia. 1 0 1
4636 26578526 Effectiveness and risks of cricoid pressure during rapid sequence induction for endotracheal intubation. 2 0 1
4637 23740788 Retinoids for preventing the progression of cervical intra-epithelial neoplasia. 2 0 1
4940 27210895 Corticosteroids for treating nerve damage in leprosy. 2 0 1
4939 18254090 Treatment for Charcot-Marie-Tooth disease. 3 0 1
4634 11869670 Surgery for lateral elbow pain. 1 0 1
4649 23543584 FSH replaced by low-dose hCG in the late follicular phase versus continued FSH for assisted reproductive techniques. 1 0 1
4651 16855976 Gonadotrophin-releasing hormone antagonists for assisted conception. 1 0 1
4670 24820247 Preoperative education for hip or knee replacement. 1 0 1
4925 22592707 Extracorporeal shock wave lithotripsy (ESWL) versus ureteroscopic management for ureteric calculi. 2 0 1
4664 12519590 Anticoagulants versus antiplatelet agents for acute ischaemic stroke. 2 0 1
4666 28540976 Antithrombotic treatment after stroke due to intracerebral haemorrhage. 2 0 1
4924 17253576 Extra-corporeal shock wave lithotripsy (ESWL) versus ureteroscopic management for ureteric calculi. 2 0 1
4667 23728675 Continuous versus intermittent physiological monitoring for acute stroke. 2 0 1
4668 23728686 Pedicle screw fixation for traumatic fractures of the thoracic and lumbar spine. 1 0 1
4926 27416073 Surgery versus non-surgical management for unilateral ureteric-pelvic junction obstruction in newborns and infants less than two years of age. 1 0 1
4669 14974019 Pre-operative education for hip or knee replacement. 1 0 1
4740 15266530 Botulinum toxin injections for the treatment of spasmodic dysphonia. 1 0 1
4730 27434597 Treatments for the prevention of Sudden Unexpected Death in Epilepsy (SUDEP). 3 0 1
4881 19821278 Endometrial resection / ablation techniques for heavy menstrual bleeding. 1 0 1
4541 24789267 Carbamazepine for schizophrenia. 3 0 1
4538 15846633 Manual versus powered toothbrushing for oral health. 2 0 1
4536 27444319 Anti-tuberculous therapy for maintenance of remission in Crohn's disease. 3 0 1
4994 21901685 Antibiotics for ureaplasma in the vagina in pregnancy. 1 0 1
4535 10796872 Antihypertensive therapy for preventing cardiovascular complications in people with diabetes mellitus. 2 0 1
4995 29768662 Immersion in water during labour and birth. 1 0 1
4996 19370552 Immersion in water in labour and birth. 1 0 1
4534 18843719 Immunoglobulin prophylaxis in hematological malignancies and hematopoietic stem cell transplantation. 2 0 1
4997 15106143 Immersion in water in pregnancy, labour and birth. 1 0 1
4998 10796138 Intrapartum antibiotics for group B streptococcal colonisation. 1 0 1
4549 10908478 Quetiapine for schizophrenia. 2 0 1
4550 22336825 Interventions for prevention of giant retinal tear in the fellow eye. 2 0 1
4551 23440808 Intravitreal low molecular weight heparin and 5-Fluorouracil for the prevention of proliferative vitreoretinopathy following retinal reattachment surgery. 2 0 1
4552 18843739 Macular translocation for neovascular age-related macular degeneration. 2 0 1
4567 22161416 Physical training for McArdle disease. 1 0 1
4566 23740606 Creatine for treating muscle disorders. 2 0 1
4565 24014170 Interventions for managing relapse of the lower front teeth after orthodontic treatment. 1 0 1
4982 15266428 Antipsychotic medication for challenging behaviour in people with learning disability. 1 0 1
4983 11686948 Antipsychotic medication for those with both schizophrenia and learning disability. 1 0 1
4564 14974028 Auditory integration training and other sound therapies for autism spectrum disorders. 1 0 1
4540 12137621 Carbamazepine for schizophrenia and schizoaffective psychoses. 2 0 1
4542 28349512 Chlorpromazine versus metiapine for schizophrenia. 2 0 1
4731 18254049 Empiric antibiotic coverage of atypical pathogens for community acquired pneumonia in hospitalized adults. 2 0 1
4543 30378678 Chlorpromazine versus piperacetazine for schizophrenia. 4 0 1
4601 28434208 Dietary interventions for adults with chronic kidney disease. 3 0 1
4600 24683046 Darbepoetin for the anaemia of chronic kidney disease. 2 0 1
4599 28782299 Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease. 3 0 1
4598 22161434 Cardiac testing for coronary artery disease in potential kidney transplant recipients. 4 0 1
4975 21975771 Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults. 1 0 1
4597 23450589 Antiplatelet agents for chronic kidney disease. 2 0 1
4596 21975774 Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non-diabetic chronic kidney disease. 2 0 1
4593 17943887 Intravesical treatments for painful bladder syndrome/ interstitial cystitis. 1 0 1
4570 22972119 Endothelin receptor antagonists for subarachnoid hemorrhage. 2 0 1
4569 10796370 Circulatory volume expansion for aneurysmal subarachnoid hemorrhage. 1 0 1
4568 28685504 Statins for children with familial hypercholesterolemia. 3 0 1
4548 17054165 Pharmacological management for agitation and aggression in people with acquired brain injury. 1 0 1
4547 24425538 Perazine for schizophrenia. 2 0 1
4546 22071847 Helicobacter pylori eradication for Parkinson's disease. 2 0 1
4545 24242360 Haloperidol versus placebo for schizophrenia. 3 0 1
4991 12076381 Antibiotics for gonorrhoea in pregnancy. 2 0 1
4992 11687090 Antibiotics for preterm premature rupture of membranes. 1 0 1
4544 24395698 Chlorpromazine versus placebo for schizophrenia. 2 0 1
4993 24297389 Antibiotics for preterm rupture of membranes. 2 0 1
4563 27344135 Aripiprazole for autism spectrum disorders (ASD). 1 0 1
4562 25425092 Salicylate-containing rubefacients for acute and chronic musculoskeletal pain in adults. 2 0 1
4561 23633343 Physical tests for shoulder impingements and local lesions of bursa, tendon or labrum that may accompany impingement. 1 0 1
4560 23440811 Intravenous immunoglobulin as adjuvant therapy for Wegener's granulomatosis. 1 0 1
4959 18646107 Vitamin B for treating peripheral neuropathy. 2 0 1
4621 21328279 Phosphate binders for preventing and treating bone disease in chronic kidney disease patients. 3 0 1
4617 28362060 Maintenance immunosuppression for adults undergoing liver transplantation: a network meta-analysis. 2 0 1
4961 26439610 Percutaneous central venous catheters versus peripheral cannulae for delivery of parenteral nutrition in neonates. 3 0 1
4952 18254012 Psychosocial interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood. 1 0 1
4619 30790278 Parenteral versus oral iron therapy for adults and children with chronic kidney disease. 3 0 1
4616 30284724 Low protein diets for non-diabetic adults with chronic kidney disease. 3 0 1
4618 25317905 Oral adsorbents for preventing or delaying the progression of chronic kidney disease. 2 0 1
4960 25879104 Zonisamide for neuropathic pain in adults. 1 0 1
4624 22786510 Rheum officinale (a traditional Chinese medicine) for chronic kidney disease. 2 0 1
4626 28066881 Short-acting erythropoiesis-stimulating agents for anaemia in predialysis patients. 2 0 1
4964 17943858 Fundal pressure versus controlled cord traction as part of the active management of the third stage of labour. 1 0 1
4627 19821446 Vitamin D compounds for people with chronic kidney disease not requiring dialysis. 2 0 1
4622 17943919 Protein restriction for children with chronic renal failure. 2 0 1
4953 25246131 Desipramine for neuropathic pain in adults. 1 0 1
4613 23440812 Interventions for HIV-associated nephropathy. 2 0 1
4623 26790135 Recombinant human erythropoietin versus placebo or no treatment for the anaemia of chronic kidney disease in people not requiring dialysis. 2 0 1
4620 23749733 Pharmacological interventions for pruritus in adult palliative care patients. 2 0 1
4957 26329307 Topical clonidine for neuropathic pain. 1 0 1
4614 17636784 Interventions for preventing bone disease in kidney transplant recipients. 3 0 1
4951 19160286 Psychological treatments for the management of irritable bowel syndrome. 1 0 1
4958 26298465 Venlafaxine for neuropathic pain in adults. 3 0 1
4988 30776081 Antibiotic treatment for newborns with congenital syphilis. 2 0 1
4612 23979995 Interventions for erythropoietin-resistant anaemia in dialysis patients. 2 0 1
4559 17253577 Immunosuppressive treatment for non-systemic vasculitic neuropathy. 1 0 1
4558 30629283 Deep brain stimulation for dystonia. 2 0 1
4557 21735426 TPO receptor agonist for chronic idiopathic thrombocytopenic purpura. 2 0 1
4985 18254027 Interventions for learning disabled sex offenders. 1 0 1
4986 18843715 Smart home technologies for health and social care support. 1 0 1
4556 27378557 Dimercaptosuccinic acid scan or ultrasound in screening for vesicoureteral reflux among children with urinary tract infections. 1 0 1
4987 10796118 Transcutaneous electrostimulation for suspected placental insufficiency (diagnosed by Doppler studies). 1 0 1
4555 21678341 Weight reduction for non-alcoholic fatty liver disease. 3 0 1
4962 28724193 Saline irrigation for the management of skin extravasation injury in neonates. 1 0 1
4554 23975682 Herbal medicines for fatty liver diseases. 3 0 1
4553 17253541 Bile acids for non-alcoholic fatty liver disease and/or steatohepatitis. 3 0 1
4984 15494985 Antipsychotic medication versus placebo for people with both schizophrenia and learning disability. 2 0 1
4965 19821262 Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care. 1 0 1
4585 26889627 Perioperative dexmedetomidine for acute pain after abdominal surgery in adults. 1 0 1
4818 26436600 Preoperative inspiratory muscle training for postoperative pulmonary complications in adults undergoing cardiac and major abdominal surgery. 1 0 1
4955 21328280 Lamotrigine for acute and chronic pain. 2 0 1
4625 28230899 Shared care across the interface between primary and specialty care in management of long term conditions. 2 0 1
4602 26376110 Dietary interventions for mineral and bone disorder in people with chronic kidney disease. 2 0 1
4603 29105079 Direct oral anticoagulants versus warfarin for preventing stroke and systemic embolic events among atrial fibrillation patients with chronic kidney disease. 5 0 1
4604 20927768 Drugs for treatment of urinary retention after surgery in adults. 2 0 1
4761 25125317 Interventions to reduce haemorrhage during myomectomy for fibroids. 2 0 1
4855 12076478 Bright light therapy for sleep problems in adults aged 60+. 1 0 1
4853 22895957 Antivirals for idiopathic sudden sensorineural hearing loss. 2 0 1
4769 28470696 Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease. 2 0 1
4851 27911983 Fibrin glue versus sutures for conjunctival autografting in primary pterygium surgery. 2 0 1
4850 15266499 Soy formula for prevention of allergy and food intolerance in infants. 1 0 1
4849 18843705 Probiotics for treating eczema. 2 0 1
4770 28114736 Cromolyn sodium for the prevention of chronic lung disease in preterm infants. 1 0 1
4854 15106256 Aripiprazole for schizophrenia. 1 0 1
4728 16235277 Surgery for obstructive sleep apnoea. 1 0 1
4860 27045603 Ganoderma lucidum (Reishi mushroom) for cancer treatment. 2 0 1
4862 29859017 Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for acute asthma. 2 0 1
4866 12519595 Physical exercise for sleep problems in adults aged 60+. 1 0 1
4754 25374369 Antibiotics for meconium-stained amniotic fluid in labour for preventing maternal and neonatal infections. 3 0 1
4755 22696345 Induction of labour for improving birth outcomes for women at or beyond term. 1 0 1
4865 25338726 Pharmacotherapy for sleep bruxism. 2 0 1
4756 14583981 Steroid therapy for meconium aspiration syndrome in newborn infants. 2 0 1
4757 27021482 Antibiotics and antiseptics for surgical wounds healing by secondary intention. 1 0 1
4861 29633783 Honey for acute cough in children. 1 0 1
4758 23235586 Homeopathic Oscillococcinum(®) for preventing and treating influenza and influenza-like illness. 2 0 1
4859 23450533 Drug therapy for preventing post-dural puncture headache. 1 0 1
4768 27210414 Antidepressants for treating depression in adults with end-stage kidney disease treated with dialysis. 3 0 1
4856 22972133 Cholinesterase inhibitors for mild cognitive impairment. 1 0 1
4737 23152266 Psychological therapies for pathological and problem gambling. 1 0 1
4733 22419303 Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia. 1 0 1
4880 16235284 Endometrial destruction techniques for heavy menstrual bleeding. 1 0 1
4879 17443576 Psychotropic analgesic nitrous oxide for alcoholic withdrawal states. 3 0 1
4752 21328307 Autologous hematopoietic stem cell transplantation following high-dose chemotherapy for non-rhabdomyosarcoma soft tissue sarcomas. 1 0 1
4878 21901695 Psychosocial and pharmacological treatments versus pharmacological treatments for opioid detoxification. 1 0 1
4735 26967103 Pharmacological treatment for Buerger's disease. 1 0 1
4736 30378681 Stem cell therapy for treatment of thromboangiitis obliterans (Buerger's disease). 2 0 1
4877 15495052 Methadone at tapered doses for the management of opioid withdrawal. 1 0 1
4876 20166080 Gamma-hydroxybutyrate (GHB) for treatment of alcohol withdrawal and prevention of relapses. 1 0 1
4767 27039404 Anticoagulants and antiplatelet agents for preventing central venous haemodialysis catheter malfunction in patients with end-stage kidney disease. 2 0 1
4739 24659320 Pharmacotherapies for sleep disturbances in Alzheimer's disease. 3 0 1
4734 15106156 Population-based interventions for reducing sexually transmitted infections, including HIV infection. 4 0 1
4753 28407197 Autologous hematopoietic stem cell transplantation following high-dose chemotherapy for nonrhabdomyosarcoma soft tissue sarcomas. 2 0 1
4868 30883669 Second-generation antidepressants for preventing seasonal affective disorder in adults. 2 0 1
4867 12535498 Placebo treatment versus no treatment. 1 0 1
4858 30577083 Cognitive-behavioural treatment for amphetamine-type stimulants (ATS)-use disorders. 1 0 1
4766 30731030 Antibiotics for induction and maintenance of remission in Crohn's disease. 2 0 1
4857 12535460 Cognitive behavioural interventions for sleep problems in adults aged 60+. 1 0 1
4760 16855981 Homoeopathic Oscillococcinum for preventing and treating influenza and influenza-like syndromes. 2 0 1
4864 26497719 Oral budesonide for induction of remission in ulcerative colitis. 3 0 1
4605 26671531 Early versus delayed erythropoietin for the anaemia of end-stage kidney disease. 2 0 1
4762 27383922 Ambulatory and short-burst oxygen for interstitial lung disease. 4 0 1
4576 29523018 Aromatherapy for treatment of postoperative nausea and vomiting. 1 0 1
4980 27858952 Subintimal angioplasty for lower limb arterial chronic total occlusions. 1 0 1
4574 28836659 Zonisamide for essential tremor. 1 0 1
4573 28409827 Topiramate for essential tremor. 1 0 1
4572 27763691 Pregabalin for essential tremor. 1 0 1
4591 30925195 Supplemental perioperative intravenous crystalloids for postoperative nausea and vomiting. 1 0 1
4571 12535472 Beta-blocker therapy for tremor in Parkinson's disease. 2 0 1
4592 25785365 Tramadol for postoperative pain treatment in children. 1 0 1
4594 27349639 Acupuncture and related interventions for symptoms of chronic kidney disease. 3 0 1
4966 11034667 Antibiotics for preventing respiratory tract infections in adults receiving intensive care. 1 0 1
4611 20091666 Interventions for bone disease in children with chronic kidney disease. 3 0 1
4968 25203308 Automated weaning and SBT systems versus non-automated weaning strategies for weaning time in invasively ventilated critically ill adults. 1 0 1
4969 17943823 Closed tracheal suction systems versus open tracheal suction systems for mechanically ventilated adult patients. 1 0 1
4610 17054191 Haemoglobin and haematocrit targets for the anaemia of chronic kidney disease. 2 0 1
4970 23543545 Interventions to improve professional adherence to guidelines for prevention of device-related infections. 1 0 1
4609 22336787 Growth hormone for children with chronic kidney disease. 2 0 1
4608 21975737 Exercise training for adults with chronic kidney disease. 2 0 1
4607 25549989 Erythropoiesis-stimulating agents for anaemia in chronic kidney disease: Are they all the same? 2 0 1
4606 25486075 Erythropoiesis-stimulating agents for anaemia in adults with chronic kidney disease: a network meta-analysis. 2 0 1
4577 16856030 Drugs for preventing postoperative nausea and vomiting. 1 0 1
4578 28806470 Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults. 1 0 1
4979 18646124 Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary edema. 1 0 1
4589 19370583 Stimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting. 1 0 1
4763 27372735 Aminosalicylates for induction of remission or response in Crohn's disease. 4 0 1
4764 27623758 Ankle brachial index for the diagnosis of lower limb peripheral arterial disease. 3 0 1
4759 25629583 Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness. 2 0 1
4628 19821349 Vitamin D compounds for people with chronic kidney disease requiring dialysis. 2 0 1
4671 24293322 Treatment for femoral pseudoaneurysms. 1 0 1
4950 16437473 Herbal medicines for treatment of irritable bowel syndrome. 1 0 1
4590 26522652 Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting. 1 0 1
4977 29401369 Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates. 1 0 1
4588 21154380 Perioperative transversus abdominis plane (TAP) blocks for analgesia after abdominal surgery. 1 0 1
4579 27419911 Epidural local anaesthetics versus opioid-based analgesic regimens for postoperative gastrointestinal paralysis, vomiting and pain after abdominal surgery. 2 0 1
4587 16437490 Perioperative ketamine for acute postoperative pain. 1 0 1
4586 30570761 Perioperative intravenous ketamine for acute postoperative pain in adults. 1 0 1
4584 29761478 Pain relief for women undergoing oocyte retrieval for assisted reproduction. 2 0 1
4583 26545294 Nitrous oxide-based techniques versus nitrous oxide-free techniques for general anaesthesia. 2 0 1
4582 25079857 Nalbuphine for postoperative pain treatment in children. 1 0 1
4581 24510622 Intravenous versus inhalational anaesthesia for paediatric outpatient surgery. 1 0 1
4978 25503538 Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer. 2 0 1
4580 11034732 Epidural local anaesthetics versus opioid-based analgesic regimens on postoperative gastrointestinal paralysis, PONV and pain after abdominal surgery. 2 0 1
4717 25030199 Inhaled corticosteroids in children with persistent asthma: dose-response effects on growth. 2 0 1
4889 18646144 Physical therapy for Bell s palsy (idiopathic facial paralysis). 2 0 1
3879 28230908 Probiotics for people with hepatic encephalopathy. 3 0 1
3733 21678356 Symptomatic oxygen for non-hypoxaemic chronic obstructive pulmonary disease. 1 0 1
3891 12918001 A comparison of active drugs for the treatment of dysthymia. 1 0 1
3739 22972134 Tiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary disease. 1 0 1
3745 23728665 Acupuncture for treating fibromyalgia. 1 0 1
3747 23235657 Amitriptyline for neuropathic pain and fibromyalgia in adults. 2 0 1
3748 26146793 Amitriptyline for neuropathic pain in adults. 1 0 1
3750 28779491 Antiepileptic drugs for chronic non-cancer pain in children and adolescents. 4 0 1
3751 24217986 Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews. 2 0 1
3752 23990266 Antipsychotics for acute and chronic pain in adults. 4 0 1
3754 25350761 Aquatic exercise training for fibromyalgia. 1 0 1
3756 24719027 Carbamazepine for chronic neuropathic pain and fibromyalgia in adults. 3 0 1
3757 22592742 Clonazepam for neuropathic pain and fibromyalgia in adults. 1 0 1
3743 11034684 Vaccines for preventing influenza in people with asthma (Cochrane Review). 2 0 1
4098 26017019 Interventions for prophylaxis of hepatic veno-occlusive disease in people undergoing haematopoietic stem cell transplantation. 2 0 1
3892 10796749 A comparison of drugs versus placebo for the treatment of dysthymia. 1 0 1
3895 16235374 Cognitive behavioural therapy for anxiety disorders in children and adolescents. 1 0 1
4027 22071815 Risk scoring systems for predicting preterm birth with the aim of reducing associated adverse outcomes. 1 0 1
4029 21901705 Specialised antenatal clinics for women with a pregnancy at high risk of preterm birth (excluding multiple pregnancy) to improve maternal and infant outcomes. 1 0 1
4030 12519621 Terbutaline pump maintenance therapy after threatened preterm labor for preventing preterm birth. 1 0 1
4031 29900526 Transplacental versus direct fetal corticosteroid treatment for accelerating fetal lung maturation where there is a risk of preterm birth. 2 0 1
3737 21901729 The effect of adding inhaled corticosteroids to tiotropium and long-acting beta(2)-agonists for chronic obstructive pulmonary disease. 1 0 1
3731 12804448 Smoking cessation for chronic obstructive pulmonary disease. 1 0 1
3775 27465317 Oxycodone for neuropathic pain in adults. 2 0 1
3730 29253921 Singing for adults with chronic obstructive pulmonary disease (COPD). 2 0 1
3777 22592741 Phenytoin for neuropathic pain and fibromyalgia in adults. 2 0 1
3779 24362925 Resistance exercise training for fibromyalgia. 1 0 1
3780 29489029 Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia. 2 0 1
3781 28990665 Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults. 1 0 1
3782 21975791 Valproic acid and sodium valproate for neuropathic pain and fibromyalgia in adults. 2 0 1
3783 28950401 Whole body vibration exercise training for fibromyalgia. 1 0 1
3784 12804478 Antidepressants for generalized anxiety disorder. 3 0 1
3785 16856115 Azapirones for generalized anxiety disorder. 2 0 1
3786 14974072 Drug therapy for anxiety in palliative care. 1 0 1
3787 21154375 Hydroxyzine for generalised anxiety disorder. 1 0 1
3764 24771480 Gabapentin for chronic neuropathic pain and fibromyalgia in adults. 2 0 1
3762 23076926 Duloxetine versus other anti-depressive agents for depression. 3 0 1
3761 24385423 Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia. 3 0 1
3760 19821395 Duloxetine for treating painful neuropathy or chronic pain. 3 0 1
3723 17943778 Self-management education for patients with chronic obstructive pulmonary disease. 1 0 1
3724 29411860 Self-management for bronchiectasis. 2 0 1
3726 15846710 Short term ambulatory oxygen for chronic obstructive pulmonary disease. 1 0 1
3727 12519559 Short-acting beta 2 agonists for stable chronic obstructive pulmonary disease. 1 0 1
3728 10908502 Short-acting beta 2 agonists for stable COPD. 1 0 1
4032 23740608 Abacavir-based triple nucleoside regimens for maintenance therapy in patients with HIV. 1 0 1
4033 14973989 Interventions for tears of the rotator cuff in adults. 1 0 1
4034 27283590 Manual therapy and exercise for rotator cuff disease. 2 0 1
4035 24782334 Platelet-rich therapies for musculoskeletal soft tissue injuries. 2 0 1
4008 25208049 Cervical stitch (cerclage) for preventing preterm birth in multiple pregnancy. 1 0 1
4009 28586127 Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. 1 0 1
4011 22336863 Different magnesium sulphate regimens for neuroprotection of the fetus for women at risk of preterm birth. 1 0 1
4012 18843732 Fetal fibronectin testing for reducing the risk of preterm birth. 1 0 1
4013 30480756 Interventions during pregnancy to prevent preterm birth: an overview of Cochrane systematic reviews. 2 0 1
4014 20091659 Intra-amniotic surfactant for women at risk of preterm birth for preventing respiratory distress in newborns. 3 0 1
4015 10796222 Magnesium for preventing preterm birth after threatened preterm labour. 1 0 1
4016 23728634 Magnesium maintenance therapy for preventing preterm birth after threatened preterm labour. 1 0 1
4018 24173691 Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour. 1 0 1
4019 24122673 Maintenance therapy with oxytocin antagonists for inhibiting preterm birth after threatened preterm labour. 1 0 1
4020 20091502 Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage. 1 0 1
4021 16437505 Prenatal administration of progesterone for preventing preterm birth. 1 0 1
4023 10796110 Prophylactic corticosteroids for preterm birth. 1 0 1
3996 16235281 Surgery for degenerative lumbar spondylosis. 5 0 1
4049 11405992 Potassium nitrate toothpaste for dentine hypersensitivity. 2 0 1
4051 17943912 Probiotics in infants for prevention of allergic disease and food hypersensitivity. 3 0 1
4077 20091534 Enteral versus parenteral nutrition for acute pancreatitis. 2 0 1
4078 23235679 Guidewire-assisted cannulation of the common bile duct for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. 1 0 1
4079 27083933 Interventions for necrotising pancreatitis. 1 0 1
4004 26905230 Yttrium-90 microsphere radioembolisation for unresectable hepatocellular carcinoma. 3 0 1
4003 15266436 Tamoxifen for hepatocellular carcinoma. 3 0 1
4002 14974055 Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse. 2 0 1
4044 30306546 Dietary modifications for infantile colic. 3 0 1
4036 19588374 A combination drug of abacavir-lamivudine-zidovudine (Trizivir) for treating HIV infection and AIDS. 2 0 1
4037 18843712 Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock. 1 0 1
4038 22895980 Adrenaline auto-injectors for the treatment of anaphylaxis with and without cardiovascular collapse in the community. 1 0 1
4039 17943821 Aldose reductase inhibitors for the treatment of diabetic polyneuropathy. 2 0 1
4040 22161426 Ayurvedic treatments for diabetes mellitus. 3 0 1
4041 23543540 Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS. 2 0 1
4042 17443608 Cotrimoxazole for prophylaxis or treatment of opportunistic infections of HIV/AIDS in patients with previous history of hypersensitivity to cotrimoxazole. 2 0 1
4043 30834516 Dental cavity liners for Class I and Class II resin-based composite restorations. 1 0 1
4045 22513951 Glucocorticoids for the treatment of anaphylaxis. 1 0 1
4001 11405995 Thiamine for Alzheimer's disease. 4 0 1
4046 14583918 Interventions for preventing falls in elderly people. 1 0 1
4025 23949874 Relaxin for preventing preterm birth. 1 0 1
4047 29182798 Pharmacological interventions for pain relief during orthodontic treatment. 1 0 1
4024 26645888 Prophylactic oral betamimetics for reducing preterm birth in women with a twin pregnancy. 1 0 1
4022 29086920 Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple pregnancy. 1 0 1
3998 25362239 Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults. 2 0 1
3999 25379990 Pharmacological interventions for somatoform disorders in adults. 2 0 1
4000 23235620 Medical and surgical treatment for ocular myasthenia. 2 0 1
3776 27582266 Oxycodone for pain in fibromyalgia in adults. 1 0 1
3774 24956205 Oxycodone for neuropathic pain and fibromyalgia in adults. 2 0 1
4719 11687075 Intravenous dexamethasone for extubation of newborn infants. 2 0 1
3853 28518283 Branched-chain amino acids for people with hepatic encephalopathy. 2 0 1
3855 23235669 Clofibrate in combination with phototherapy for unconjugated neonatal hyperbilirubinaemia. 1 0 1
3856 15495041 Dopaminergic agonists for hepatic encephalopathy. 2 0 1
3857 24510739 Elective birth at 37 weeks' gestation for women with an uncomplicated twin pregnancy. 2 0 1
3858 26690497 Fetal electrocardiogram (ECG) for fetal monitoring during labour. 3 0 1
3859 25287809 Fetal pulse oximetry for fetal assessment in labour. 2 0 1
3860 16034927 Fluid restriction for term infants with hypoxic-ischaemic encephalopathy following perinatal asphyxia. 2 0 1
3861 28796283 Flumazenil versus placebo or no intervention for people with cirrhosis and hepatic encephalopathy. 2 0 1
3862 25300173 High-dose versus low-dose oxytocin infusion regimens for induction of labour at term. 5 0 1
3863 24913724 Home- versus hospital-based phototherapy for the treatment of non-haemolytic jaundice in infants at more than 37 weeks' gestation. 2 0 1
3865 29741208 Induction of labour for improving birth outcomes for women at or beyond term. 2 0 1
3790 25230088 Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults. 2 0 1
3789 17253466 Psychological therapies for generalised anxiety disorder. 1 0 1
3788 29048739 Pharmacotherapy for social anxiety disorder (SAnD). 1 0 1
3690 11279755 Methyl-xanthines for exacerbations of chronic obstructive pulmonary disease. 1 0 1
3692 23440837 Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease. 1 0 1
3693 29845600 Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease. 2 0 1
3694 23766138 Nocturnal non-invasive positive pressure ventilation for stable chronic obstructive pulmonary disease. 1 0 1
3695 15266518 Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease. 2 0 1
3696 23235608 Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma. 4 0 1
3854 24030708 Caesarean section versus vaginal delivery for preterm birth in singletons. 2 0 1
3852 12804416 Branched-chain amino acids for hepatic encephalopathy. 2 0 1
3772 29652088 Non-invasive brain stimulation techniques for chronic pain. 1 0 1
3851 21249655 Bile acids for primary sclerosing cholangitis. 4 0 1
3880 28349526 Pushing/bearing down methods for the second stage of labour. 1 0 1
3881 20166062 Routine intracranial pressure monitoring in acute coma. 1 0 1
3882 16437499 Sodium bicarbonate infusion during resuscitation of infants at birth. 1 0 1
3883 26337958 Standardised formal resuscitation training programmes for reducing mortality and morbidity in newborn infants. 1 0 1
3886 30123976 Xenon as an adjuvant to therapeutic hypothermia in near-term and term newborns with hypoxic-ischaemic encephalopathy. 3 0 1
3887 11687050 Fish oil in people with type 2 diabetes mellitus. 3 0 1
3888 16034947 Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV. 3 0 1
3889 22419296 Caesarean section for non-medical reasons at term. 1 0 1
3890 12804418 Interventions for suspected placenta praevia. 1 0 1
3867 25929461 Intrapartum fetal scalp lactate sampling for fetal assessment in the presence of a non-reassuring fetal heart rate trace. 2 0 1
3842 22786499 Allopurinol for preventing mortality and morbidity in newborn infants with hypoxic-ischaemic encephalopathy. 3 0 1
3866 16625578 Interventions for paracetamol (acetaminophen) overdose. 2 0 1
3864 23450604 Hypothermia for neuroprotection in children after cardiopulmonary arrest. 3 0 1
3844 12804404 Aminopyridines for symptomatic treatment in multiple sclerosis. 2 0 1
3845 27556818 Amnioinfusion for chorioamnionitis. 5 0 1
3846 24453049 Amnioinfusion for meconium-stained liquor in labour. 4 0 1
3848 14974025 Artificial and bioartificial support systems for liver failure. 3 0 1
3849 11687160 Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy. 4 0 1
3850 15106178 Benzodiazepine receptor antagonists for hepatic encephalopathy. 3 0 1
3698 28702957 Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease. 3 0 1
3699 20687075 Noninvasive positive pressure ventilation as a weaning strategy for intubated adults with respiratory failure. 3 0 1
3700 24323843 Noninvasive positive-pressure ventilation as a weaning strategy for intubated adults with respiratory failure. 3 0 1
3702 10908481 Nutritional supplementation in stable chronic obstructive pulmonary disease. 1 0 1
3669 11869676 Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease. 1 0 1
3671 27830584 Inhaled corticosteroids with combination inhaled long-acting beta2-agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease. 2 0 1
3672 11406052 Inhaled short-acting beta2-agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease. 1 0 1
3674 15846642 Inhaled tiotropium for stable chronic obstructive pulmonary disease. 1 0 1
3675 21069668 Injectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary disease. 1 0 1
3676 24108523 Integrated disease management interventions for patients with chronic obstructive pulmonary disease. 1 0 1
3678 16856113 Ipratropium bromide versus long-acting beta-2 agonists for stable chronic obstructive pulmonary disease. 1 0 1
3679 16625543 Ipratropium bromide versus short acting beta-2 agonists for stable chronic obstructive pulmonary disease. 1 0 1
3680 22513969 Long-acting beta(2)-agonist in addition to tiotropium versus either tiotropium or long-acting beta(2)-agonist alone for chronic obstructive pulmonary disease. 1 0 1
3682 12137617 Long-acting beta2-agonists for chronic obstructive pulmonary disease patients with poorly reversible airflow limitation. 1 0 1
3686 26798035 Long-acting muscarinic antagonists (LAMA) added to combination long-acting beta2-agonists and inhaled corticosteroids (LABA/ICS) versus LABA/ICS for adults with asthma. 2 0 1
3718 30838649 Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease. 2 0 1
3721 24665053 Self management for patients with chronic obstructive pulmonary disease. 1 0 1
3722 12535447 Self-management education for chronic obstructive pulmonary disease. 1 0 1
3766 22336864 Lacosamide for neuropathic pain and fibromyalgia in adults. 3 0 1
3767 24297457 Lamotrigine for chronic neuropathic pain and fibromyalgia in adults. 3 0 1
3768 26148202 Milnacipran for neuropathic pain in adults. 1 0 1
3770 30080242 Mirtazapine for fibromyalgia in adults. 1 0 1
3771 10796458 Multidisciplinary rehabilitation for fibromyalgia and musculoskeletal pain in working age adults. 2 0 1
3668 16437444 Influenza vaccine for patients with chronic obstructive pulmonary disease. 2 0 1
3666 22696389 Hospital at home in chronic obstructive pulmonary disease: Is it a viable option? 1 0 1
3665 22592692 Hospital at home for acute exacerbations of chronic obstructive pulmonary disease. 1 0 1
3714 19370631 Pneumococcal vaccines for children and adults with bronchiectasis. 3 0 1
3703 30839102 Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease. 2 0 1
3704 30141826 Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease. 2 0 1
3706 11405984 Oral corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. 1 0 1
3707 12519617 Oral theophylline for chronic obstructive pulmonary disease. 1 0 1
3709 17443585 Oxygen therapy during exercise training in chronic obstructive pulmonary disease. 2 0 1
3710 16856102 Oxygen therapy in the pre-hospital setting for acute exacerbations of chronic obstructive pulmonary disease. 1 0 1
3711 22071851 Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease. 1 0 1
3712 30566235 Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease. 2 0 1
3688 26196545 Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma. 2 0 1
3664 15674925 Home versus center based physical activity programs in older adults. 4 0 1
3716 11869627 Pressurised metered-dose inhalers versus all other hand-held inhalers devices to deliver bronchodilators for chronic obstructive pulmonary disease. 1 0 1
3687 26031392 Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus addition of long-acting beta2-agonists (LABA) for adults with asthma. 2 0 1
3683 16855959 Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease. 1 0 1
3659 16235285 Domiciliary oxygen for chronic obstructive pulmonary disease. 1 0 1
3660 30521694 Dual combination therapy versus long-acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta-analysis. 2 0 1
3661 28651296 Early discharge hospital at home. 1 0 1
3662 12076487 Heliox for treatment of exacerbations of chronic obstructive pulmonary disease. 2 0 1
3663 22513899 Home care by outreach nursing for chronic obstructive pulmonary disease. 1 0 1
4080 29641848 Laparoscopic-endoscopic rendezvous versus preoperative endoscopic sphincterotomy in people undergoing laparoscopic cholecystectomy for stones in the gallbladder and bile duct. 2 0 1
4081 27075711 Management strategies for pancreatic pseudocysts. 1 0 1
4083 19821359 Pancreatic enzymes for chronic pancreatitis. 1 0 1
3953 21491394 Anticoagulation for patients with cancer and central venous catheters. 1 0 1
3955 29363105 Anticoagulation for the initial treatment of venous thromboembolism in people with cancer. 3 0 1
3956 18425959 Anticoagulation for the long term treatment of venous thromboembolism in patients with cancer. 1 0 1
3957 25004410 Anticoagulation for the long-term treatment of venous thromboembolism in patients with cancer. 1 0 1
3958 29920657 Anticoagulation for the long-term treatment of venous thromboembolism in people with cancer. 2 0 1
3894 29513392 Cannabis-based medicines for chronic neuropathic pain in adults. 1 0 1
3959 23897323 Antifibrinolytics (lysine analogues) for the prevention of bleeding in patients with haematological disorders. 2 0 1
3961 29758592 Comparison of a therapeutic-only versus prophylactic platelet transfusion policy for people with congenital or acquired bone marrow failure disorders. 3 0 1
3962 26814707 Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia. 1 0 1
3963 23235597 Erythropoietin or darbepoetin for patients with cancer. 1 0 1
3964 29624208 Gemcitabine-based chemotherapy for advanced biliary tract carcinomas. 1 0 1
3965 23955506 Heparin for assisted reproduction. 1 0 1
3966 24825673 Heparin versus normal saline for patency of arterial lines. 3 0 1
3967 18425889 Heparin versus placebo for acute coronary syndromes. 2 0 1
3968 24972265 Heparin versus placebo for non-ST elevation acute coronary syndromes. 2 0 1
3969 24569952 Heparin-bonded catheters for prolonging the patency of central venous catheters in children. 1 0 1
3960 26978005 Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders. 2 0 1
4531 26358158 Exercise therapy for fatigue in multiple sclerosis. 2 0 1
0 21901710 Acupuncture for slowing the progression of myopia in children and adolescents. 1 0 1
4776 30098021 Enteral nutrition for maintenance of remission in Crohn's disease. 2 0 1
3954 24945634 Anticoagulation for the initial treatment of venous thromboembolism in patients with cancer. 1 0 1
3952 21563140 Antenatal interventions for fetomaternal alloimmune thrombocytopenia. 1 0 1
4084 28431202 Pharmacological interventions for acute pancreatitis. 2 0 1
3951 27069420 Alternative agents versus prophylactic platelet transfusion for preventing bleeding in patients with thrombocytopenia due to chronic bone marrow failure: a network meta-analysis and systematic review. 1 0 1
3979 25842375 Quinine for muscle cramps. 1 0 1
3980 16625599 Target of rapamycin inhibitors (TOR-I; sirolimus and everolimus) for primary immunosuppression in kidney transplant recipients. 2 0 1
3981 28962071 Thrombopoietin mimetics for patients with myelodysplastic syndromes. 4 0 1
3982 29178132 Thrombopoietin receptor agonists for prevention and treatment of chemotherapy-induced thrombocytopenia in patients with solid tumours. 1 0 1
3983 27731885 Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. 3 0 1
3984 29709077 Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in people with thrombocytopenia. 2 0 1
3985 16437496 Drug treatment for myotonia. 2 0 1
3986 10796313 Anticoagulants for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attacks. 2 0 1
3987 10796315 Anticoagulants versus antiplatelet therapy for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attacks. 2 0 1
3988 16235290 Antiplatelet therapy for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks. 2 0 1
3989 10796314 Antiplatelet therapy for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attacks. 2 0 1
3990 26346232 Closure versus medical therapy for preventing recurrent stroke in patients with patent foramen ovale and a history of cryptogenic stroke or transient ischemic attack. 3 0 1
3991 23543566 Non-pharmacological interventions for preventing secondary vascular events after stroke or transient ischemic attack. 2 0 1
3992 17636831 Oral anticoagulants versus antiplatelet therapy for preventing stroke in patients with non-valvular atrial fibrillation and no history of stroke or transient ischemic attacks. 3 0 1
3973 24771319 Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-leg immobilization. 2 0 1
3972 26758498 Linezolid versus vancomycin for skin and soft tissue infections. 2 0 1
3971 30893466 Linezolid for drug-resistant pulmonary tuberculosis. 2 0 1
3970 20091551 Interleukin 2 receptor antagonists for kidney transplant recipients. 1 0 1
3950 27797129 Alternative agents to prophylactic platelet transfusion for preventing bleeding in people with thrombocytopenia due to chronic bone marrow failure: a meta-analysis and systematic review. 1 0 1
4701 10796396 Ketanserin for Raynaud's phenomenon in progressive systemic sclerosis. 3 0 1
4700 10796395 Iloprost and cisaprost for Raynaud's phenomenon in progressive systemic sclerosis. 3 0 1
4699 10796397 Cyclofenil for Raynaud's phenomenon in progressive systemic sclerosis. 3 0 1
4903 16235361 Vaccines for measles, mumps and rubella in children. 3 0 1
4687 15674927 Braces and orthoses for treating osteoarthritis of the knee. 1 0 1
4916 12519564 Vitamin A supplementation during pregnancy. 1 0 1
4690 20464751 Joint lavage for osteoarthritis of the knee. 2 0 1
4691 10796306 Non-aspirin, non-steroidal anti-inflammatory drugs for osteoarthritis of the knee. 2 0 1
4915 26503498 Vitamin A supplementation during pregnancy for maternal and newborn outcomes. 1 0 1
4918 21563170 Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis). 2 0 1
4921 21412921 Haematological interventions for treating disseminated intravascular coagulation during pregnancy and postpartum. 1 0 1
4901 12519571 Prophylactic antibiotic administration in pregnancy to prevent infectious morbidity and mortality. 2 0 1
4703 23235682 Teriflunomide for multiple sclerosis. 2 0 1
4726 26474355 Rescue high-frequency jet ventilation versus conventional ventilation for severe pulmonary dysfunction in preterm infants. 1 0 1
4725 16437423 Rescue high frequency jet ventilation versus conventional ventilation for severe pulmonary dysfunction in preterm infants. 1 0 1
4883 21491409 Community wide interventions for increasing physical activity. 2 0 1
4724 10796717 Oral steroids for cystic fibrosis. 3 0 1
4884 11687181 Interventions for providers to promote a patient-centred approach in clinical consultations. 1 0 1
4723 16437488 Oral appliances for obstructive sleep apnoea. 1 0 1
4885 15266457 Aciclovir or valaciclovir for Bell's palsy (idiopathic facial paralysis). 2 0 1
4722 11869578 Nebulized racemic epinephrine for extubation of newborn infants. 2 0 1
4721 16235410 Long-acting beta2-agonists versus placebo in addition to inhaled corticosteroids in children and adults with chronic asthma. 2 0 1
4720 17054161 Long-acting beta2-agonists versus anti-leukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma. 2 0 1
4686 18254069 Arthroscopic debridement for knee osteoarthritis. 2 0 1
4685 17943863 Aquatic exercise for the treatment of knee and hip osteoarthritis. 1 0 1
4902 15266472 Interventions for the treatment of Morton's neuroma. 2 0 1
4911 16855968 Patient support and education for promoting adherence to highly active antiretroviral therapy for HIV/AIDS. 2 0 1
4904 20824837 Acamprosate for alcohol dependence. 2 0 1
4905 16856072 Alcoholics Anonymous and other 12-step programmes for alcohol dependence. 1 0 1
4906 24523233 Anticonvulsants for alcohol dependence. 1 0 1
4907 29688573 Antidepressants for the treatment of people with co-occurring depression and alcohol dependence. 1 0 1
4697 11034768 Transcutaneous electrical nerve stimulation for knee osteoarthritis. 2 0 1
4908 30484285 Baclofen for alcohol use disorder. 1 0 1
4909 27878808 Interventions for tobacco use cessation in people in treatment for or recovery from substance use disorders. 1 0 1
4910 21154349 Opioid antagonists for alcohol dependence. 1 0 1
4912 18646166 Psychosocial interventions for women enrolled in alcohol treatment during pregnancy. 1 0 1
4684 15266497 Vasopressors for shock. 1 0 1
4695 28497473 Topical analgesics for acute and chronic pain in adults - an overview of Cochrane Reviews. 2 0 1
4694 26017279 Tapentadol for chronic musculoskeletal pain in adults. 2 0 1
4693 30801133 Paracetamol versus placebo for knee and hip osteoarthritis. 2 0 1
4920 25581507 Vestibular rehabilitation for unilateral peripheral vestibular dysfunction. 1 0 1
4680 11869591 Intravenous immunoglobulin for treating sepsis and septic shock. 1 0 1
4681 24043371 Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock. 1 0 1
4682 30536956 Liberal versus conservative fluid therapy in adults and children with sepsis or septic shock. 1 0 1
4683 25568981 Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients. 1 0 1
3978 30221749 Prophylactic platelet transfusions prior to surgery for people with a low platelet count. 2 0 1
3977 28073178 Polyclonal and monoclonal antibodies for induction therapy in kidney transplant recipients. 2 0 1
3976 26633102 Mycophenolic acid versus azathioprine as primary immunosuppression for kidney transplant recipients. 1 0 1
3925 25719224 Endoscopic ultrasound versus magnetic resonance cholangiopancreatography for common bile duct stones. 2 0 1
4058 18843714 Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth. 2 0 1
4059 17943907 Ultrasonic versus hand instrumentation for orthograde root canal treatment of permanent teeth. 2 0 1
4061 23543579 The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission. 2 0 1
4062 24953826 Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in peritoneal dialysis patients. 1 0 1
4064 27454104 Enzyme replacement therapy for Anderson-Fabry disease. 2 0 1
4065 11406041 Diuretic therapy for newborn infants with posthemorrhagic ventricular dilatation. 2 0 1
4066 28176308 Fluid restriction for treatment of preterm infants with chronic lung disease. 4 0 1
4067 20464721 Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis. 2 0 1
4068 25144441 Antioxidants for pain in chronic pancreatitis. 1 0 1
4069 27192092 Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis. 7 0 1
4070 25081347 Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn's disease. 3 0 1
4071 15674909 Chinese medicinal herbs for acute pancreatitis. 2 0 1
4072 23996398 Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis. 2 0 1
4074 25790326 Endoscopic or surgical intervention for painful obstructive chronic pancreatitis. 1 0 1
3995 28671265 Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy, radiotherapy, or surgery). 2 0 1
3994 16034926 Triflusal for preventing serious vascular events in people at high risk. 2 0 1
3993 30964558 Prehospital stroke scales as screening tools for early identification of stroke and transient ischemic attack. 2 0 1
3922 16437475 D-penicillamine for primary sclerosing cholangitis. 2 0 1
3923 22592743 Early routine endoscopic retrograde cholangiopancreatography strategy versus early conservative management strategy in acute gallstone pancreatitis. 2 0 1
4057 23543577 Sulthiame add-on therapy for epilepsy. 1 0 1
4056 26123045 Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy. 2 0 1
4055 17054168 Progesterone for Premenstrual Syndrome. 1 0 1
4093 24379104 Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy. 2 0 1
4085 26836292 Pregabalin for decreasing pancreatic pain in chronic pancreatitis. 1 0 1
4086 28431198 Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis. 2 0 1
4087 28431197 Serum C-reactive protein, procalcitonin, and lactate dehydrogenase for the diagnosis of pancreatic necrosis. 2 0 1
4088 29185258 Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy. 2 0 1
4089 15495046 Cytotoxic drugs and interferons for chronic inflammatory demyelinating polyradiculoneuropathy. 2 0 1
4090 28481421 Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy. 2 0 1
4091 16034892 Immunosuppressant and immunomodulatory treatments for multifocal motor neuropathy. 1 0 1
4092 12076474 Immunosuppressive treatment for multifocal motor neuropathy. 1 0 1
4094 26305459 Plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy. 2 0 1
4054 30080246 Effects of all-trans retinoic acid (ATRA) in addition to chemotherapy for adults with acute myeloid leukaemia (AML) (non-acute promyelocytic leukaemia (non-APL)). 3 0 1
4095 28084646 Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews. 3 0 1
4096 19370618 Combination chemotherapy for high-risk gestational trophoblastic tumour. 1 0 1
4076 25803695 Enteral nutrition formulations for acute pancreatitis. 2 0 1
4050 17943911 Prebiotics in infants for prevention of allergic disease and food hypersensitivity. 3 0 1
4075 25719222 Endoscopic retrograde cholangiopancreatography versus intraoperative cholangiography for diagnosis of common bile duct stones. 1 0 1
4073 17054222 Endoscopic balloon sphincter dilation (sphincteroplasty) versus sphincterotomy for common bile duct stones. 2 0 1
4052 20556770 Urate oxidase for the prevention and treatment of tumor lysis syndrome in children with cancer. 2 0 1
4053 11405968 Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids. 1 0 1
3924 15495060 Endoscopic retrograde cholangiopancreatography in gallstone-associated acute pancreatitis. 3 0 1
3926 18843724 Methods of preventing bacterial sepsis and wound complications for liver transplantation. 2 0 1
3975 19821437 Medical treatments for idiopathic thrombocytopenic purpura during pregnancy. 3 0 1
3927 27182692 Pancreatic duct guidewire placement for biliary cannulation for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. 2 0 1
3901 23235633 Managed alcohol as a harm reduction intervention for alcohol addiction in populations at high risk for substance abuse. 3 0 1
3902 22972147 Motivational interviewing for improving outcomes in youth living with HIV. 1 0 1
3903 21563163 Motivational interviewing for substance abuse. 1 0 1
3904 14974014 Psychological and/or educational interventions for the prevention of depression in children and adolescents. 1 0 1
3905 16437534 Psychological therapies for people with borderline personality disorder. 1 0 1
3906 21154379 Treatment for inhalant dependence and abuse. 1 0 1
3907 15846700 Treatment for methaqualone dependence in adults. 1 0 1
3908 24760679 Medically assisted nutrition for adult palliative care patients. 1 0 1
3909 25503955 Nocturnal mechanical ventilation for chronic hypoventilation in patients with neuromuscular and chest wall disorders. 3 0 1
3910 16034940 Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. 1 0 1
3912 12918012 Vitamin B12 for cognition. 2 0 1
3914 22161367 Interventions for preventing obesity in children. 2 0 1
3915 12917914 Interventions for treating obesity in children. 1 0 1
3916 24627300 Lifestyle intervention for improving school achievement in overweight or obese children and adolescents. 2 0 1
3918 26544539 Ethanol for preventing preterm birth in threatened preterm labor. 2 0 1
3945 24323844 Rehabilitation following surgery for lumbar spinal stenosis. 3 0 1
3946 27801521 Surgical options for lumbar spinal stenosis. 3 0 1
3948 15846686 Interventions for treating asymptomatic impacted wisdom teeth in adolescents and adults. 2 0 1
3974 12535430 Low molecular weight heparins versus unfractionated heparin for acute coronary syndromes. 2 0 1
3900 22592676 Interventions for smoking cessation in hospitalised patients. 1 0 1
3899 11034701 Drugs versus placebo for dysthymia. 1 0 1
3898 11687059 Day hospital versus out-patient care for psychiatric disorders. 1 0 1
3937 27329345 Lamotrigine add-on for drug-resistant partial epilepsy. 3 0 1
3928 12137669 Ursodeoxycholic acid and/or antibiotics for prevention of biliary stent occlusion. 1 0 1
3929 27614728 Different antibiotic treatments for group A streptococcal pharyngitis. 3 0 1
3930 22895944 Short-term late-generation antibiotics versus longer term penicillin for acute streptococcal pharyngitis in children. 3 0 1
3931 14973998 Treatment for lupus nephritis. 1 0 1
3932 19160272 Interventions for pemphigus vulgaris and pemphigus foliaceus. 2 0 1
3933 26631369 Interventions for treating gas gangrene. 1 0 1
3934 23737031 Elective preterm birth for fetal gastroschisis. 3 0 1
3935 12137704 Ward reduction without general anaesthesia versus reduction and repair under general anaesthesia for gastroschisis in newborn infants. 2 0 1
3938 29691835 Rufinamide add-on therapy for refractory epilepsy. 6 0 1
3897 22161384 Day hospital versus admission for acute psychiatric disorders. 1 0 1
3939 19160204 Interventions for acute non-arteritic central retinal artery occlusion. 1 0 1
3941 24085641 Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants. 1 0 1
3942 12917947 Immunomodulatory agents for idiopathic pulmonary fibrosis. 4 0 1
3920 26445202 Implantable defibrillators versus medical therapy for cardiac channelopathies. 6 0 1
3943 22071848 Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies. 3 0 1
3919 11406062 Family and parenting interventions in children and adolescents with conduct disorder and delinquency aged 10-17. 1 0 1
3917 18254068 Treatment for periodic paralysis. 3 0 1
3896 17636823 Cognitive behavioural therapy for men who physically abuse their female partner. 1 0 1
6056 20927761 Percutaneous vascular interventions for acute ischaemic stroke. 1 0 1
6054 19588381 Overground physical therapy gait training for chronic stroke patients with mobility deficits. 1 0 1
1010 26765344 Vitamin D supplementation for women during pregnancy. 4 0 1
5816 23744561 Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis. 1 0 1
5819 20091602 Interferon Beta for primary progressive multiple sclerosis. 1 0 1
5820 22258960 Interferon beta for secondary progressive multiple sclerosis. 1 0 1
5821 11687131 Interferon in relapsing-remitting multiple sclerosis. 1 0 1
5822 27880972 Interferons-beta versus glatiramer acetate for relapsing-remitting multiple sclerosis. 1 0 1
5823 14583956 Intravenous immunoglobulins for multiple sclerosis. 1 0 1
5824 27004596 Memory rehabilitation for people with multiple sclerosis. 1 0 1
5825 15106195 Methotrexate for multiple sclerosis. 1 0 1
5828 24515630 Neuropsychological rehabilitation for multiple sclerosis. 1 0 1
5829 23450612 Non pharmacological interventions for spasticity in multiple sclerosis. 1 0 1
5830 30567012 Non-pharmacological interventions for chronic pain in multiple sclerosis. 1 0 1
5833 21328292 Pharmacologic treatment of depression in multiple sclerosis. 1 0 1
5834 24343792 Pharmacological treatment for memory disorder in multiple sclerosis. 1 0 1
5835 26026155 Pharmacological treatments for fatigue associated with palliative care. 1 0 1
5758 22786526 Weight loss interventions for chronic asthma. 2 0 1
5424 24470114 Clonidine premedication for postoperative analgesia in children. 1 0 1
5757 24500864 Transtheoretical model stages of change for dietary and physical exercise modification in weight loss management for overweight and obese adults. 1 0 1
5755 24443105 Tracheal intubation with a flexible intubation scope versus other intubation techniques for obese patients requiring general anaesthesia. 1 0 1
5677 16625591 Insecticide-treated nets for preventing malaria in pregnancy. 1 0 1
5678 30398672 Insecticide-treated nets for preventing malaria. 1 0 1
5818 30317542 Information provision for people with multiple sclerosis. 1 0 1
5814 27091121 Fingolimod for relapsing-remitting multiple sclerosis. 1 0 1
5850 27457661 Advance care planning for haemodialysis patients. 1 0 1
5812 19160331 Effectiveness of vocational rehabilitation intervention on the return to work and employment of persons with multiple sclerosis. 1 0 1
5852 23235603 Antihypertensive agents for preventing diabetic kidney disease. 1 0 1
5853 26457607 Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients. 1 0 1
5840 17253537 Treatment for ataxia in multiple sclerosis. 1 0 1
5854 29376218 Early versus late ureteric stent removal after kidney transplantation. 1 0 1
5856 24872328 Frequency of administration of erythropoiesis-stimulating agents for the anaemia of end-stage kidney disease in dialysis patients. 1 0 1
5857 28238223 Glucose-lowering agents for treating pre-existing and new-onset diabetes in kidney transplant recipients. 1 0 1
5858 25993563 Haemodiafiltration, haemofiltration and haemodialysis for end-stage kidney disease. 1 0 1
5859 24022428 HMG CoA reductase inhibitors (statins) for dialysis patients. 1 0 1
5860 25412074 Home versus in-centre haemodialysis for end-stage kidney disease. 1 0 1
5861 25938479 Interventions for lowering plasma homocysteine levels in kidney transplant recipients. 1 0 1
5862 30875082 Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation. 1 0 1
5863 25579852 Vitamin B and its derivatives for diabetic kidney disease. 1 0 1
5855 21678365 Education programmes for people with diabetic kidney disease. 1 0 1
5839 22161428 Statins for multiple sclerosis. 2 0 1
5838 30637728 Rehabilitation for people with multiple sclerosis: an overview of Cochrane Reviews. 1 0 1
5837 18425915 Recombinant interferon beta or glatiramer acetate for delaying conversion of the first demyelinating event to multiple sclerosis. 1 0 1
5808 22592719 Carnitine for fatigue in multiple sclerosis. 1 0 1
5809 11034713 Corticosteroids or ACTH for acute exacerbations in multiple sclerosis. 1 0 1
5810 24363032 Daclizumab for relapsing remitting multiple sclerosis. 1 0 1
5681 21975756 Intermittent preventive treatment regimens for malaria in HIV-positive pregnant women. 1 0 1
5682 15495107 Intramuscular arteether for treating severe malaria. 1 0 1
5683 15674922 Intrarectal quinine for treating Plasmodium falciparum malaria. 1 0 1
5684 19160229 Intrarectal quinine versus intravenous or intramuscular quinine for treating Plasmodium falciparum malaria. 1 0 1
5653 16235366 Atovaquone-proguanil for treating uncomplicated malaria. 1 0 1
5654 21328286 Azithromycin for treating uncomplicated malaria. 1 0 1
5655 18425893 Chemoprophylaxis and intermittent treatment for preventing malaria in children. 1 0 1
5656 16235276 Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria. 1 0 1
5657 15495106 Chlorproguanil-dapsone for treating uncomplicated malaria. 1 0 1
5672 28895659 Implementation strategies for health systems in low-income countries: an overview of systematic reviews. 2 0 1
5658 26198451 Daily oral iron supplementation during pregnancy. 1 0 1
5660 24443033 Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria. 1 0 1
5662 17054128 Drugs for preventing malaria in pregnant women. 1 0 1
5663 19821371 Drugs for preventing malaria in travellers. 1 0 1
5664 12535391 Drugs for preventing malaria-related illness in pregnant women and death in the newborn. 1 0 1
5665 18843672 Drugs for treating uncomplicated malaria in pregnant women. 1 0 1
5667 30973639 First aid glucose administration routes for symptomatic hypoglycaemia. 1 0 1
5668 26621223 Health system and community level interventions for improving antenatal care coverage and health outcomes. 2 0 1
5669 15266481 High first dose quinine regimen for treating severe malaria. 1 0 1
5670 21901727 Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age. 1 0 1
5659 28901005 Delivery arrangements for health systems in low-income countries: an overview of systematic reviews. 1 0 1
5701 17253504 Primaquine for preventing relapses in people with Plasmodium vivax malaria. 1 0 1
5702 22972117 Primaquine for reducing Plasmodium falciparum transmission. 1 0 1
5652 21901735 Assessing rapid diagnostic tests for malaria. 1 0 1
5650 24596021 Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria. 1 0 1
5649 16235367 Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria. 1 0 1
5694 29405263 Mosquito repellents for malaria prevention. 1 0 1
5685 12804409 Iron chelating agents for treating malaria. 1 0 1
5686 19160298 Iron supplementation for reducing morbidity and mortality in children with HIV. 1 0 1
5687 10796140 Iron supplementation in pregnancy. 1 0 1
5676 10796535 Insecticide-treated bednets and curtains for preventing malaria. 1 0 1
5688 29226959 Larvivorous fish for preventing malaria transmission. 1 0 1
5690 24318836 Mass drug administration for malaria. 1 0 1
5691 11034675 Mefloquine for preventing malaria in non-immune adult travellers. 1 0 1
5692 30480761 Mefloquine for preventing malaria in pregnant women. 1 0 1
5695 19588399 Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas. 1 0 1
5648 25702785 Artemisinin-naphthoquine for treating uncomplicated Plasmodium falciparum malaria. 1 0 1
5696 26921618 Oral iron supplements for children in malaria-endemic areas. 1 0 1
5697 30488945 Piperonyl butoxide (PBO) combined with pyrethroids in insecticide-treated nets to prevent malaria in Africa. 1 0 1
5698 24869943 Pre-referral rectal artesunate for severe malaria. 1 0 1
5699 10796500 Prevention versus treatment for malaria in pregnant women. 1 0 1
5689 21491391 Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria. 1 0 1
5700 24163057 Primaquine for preventing relapse in people with Plasmodium vivax malaria treated with chloroquine. 1 0 1
5674 30388303 Insecticide space spraying for preventing malaria transmission. 1 0 1
5671 23728693 Home- or community-based programmes for treating malaria. 1 0 1
5851 17054288 Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease. 1 0 1
5847 17943844 Immunosuppressive agents for myasthenia gravis. 1 0 1
5518 29940078 Descemet's membrane endothelial keratoplasty (DMEK) versus Descemet's stripping automated endothelial keratoplasty (DSAEK) for corneal endothelial failure. 1 0 1
5490 27545762 Exercise prior to influenza vaccination for limiting influenza incidence and its related complications in adults. 1 0 1
5493 23904194 Influenza vaccination in children being treated with chemotherapy for cancer. 1 0 1
5494 17636836 Influenza vaccine for children and adults with bronchiectasis. 2 0 1
5495 18646119 Influenza vaccines for preventing coronary heart disease. 1 0 1
5496 29388675 Influenza vaccines in immunosuppressed adults with cancer. 2 0 1
5497 29845606 Interventions to increase influenza vaccination rates of those 60 years and older in the community. 1 0 1
5498 11279712 Mucolytics for bronchiectasis. 1 0 1
5499 22336870 Neuraminidase inhibitors for influenza: methods change, principles don't. 1 0 1
5500 20166059 Neuraminidase inhibitors for preventing and treating influenza in healthy adults. 1 0 1
5502 29388197 Vaccines for preventing influenza in the elderly. 1 0 1
5644 10796551 Artemisinin derivatives for treating severe malaria. 1 0 1
5645 10796519 Artemisinin derivatives for treating uncomplicated malaria. 1 0 1
5646 19588433 Artemisinin-based combination therapy for treating uncomplicated malaria. 1 0 1
5647 24163021 Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria. 1 0 1
5783 26510094 Sulthiame add-on therapy for epilepsy. 2 0 1
5784 30883670 Light therapy for preventing seasonal affective disorder. 1 0 1
5785 26560173 Melatonin and agomelatine for preventing seasonal affective disorder. 1 0 1
5786 26560172 Psychological therapies for preventing seasonal affective disorder. 1 0 1
5787 22161433 Second-generation antidepressants for seasonal affective disorder. 1 0 1
5788 17054182 Anticholinergics for neuroleptic-induced acute akathisia. 1 0 1
5492 20166073 Influenza vaccination for healthcare workers who work with the elderly. 1 0 1
5489 19588375 Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB). 1 0 1
5845 15846640 Corticosteroids for myasthenia gravis. 1 0 1
5488 23543533 Chinese medicinal herbs for influenza. 1 0 1
5521 25826743 Buprenorphine for treating cancer pain. 1 0 1
5522 26561338 Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy. 1 0 1
5523 28850174 Chemotherapy for advanced gastric cancer. 1 0 1
5524 30039853 Communication skills training for healthcare professionals working with people who have cancer. 1 0 1
5525 25914908 Diagnostic accuracy of endoscopic ultrasonography (EUS) for the preoperative locoregional staging of primary gastric cancer. 2 0 1
5526 28603881 Early palliative care for adults with advanced cancer. 1 0 1
5527 27883365 Educational interventions for the management of cancer-related fatigue in adults. 1 0 1
5517 16856023 Radiotherapy for malignant pleural mesothelioma. 1 0 1
5505 30882896 Hydroxyurea (hydroxycarbamide) for transfusion-dependent β-thalassaemia. 1 0 1
5504 19588423 Erythropoietin or Darbepoetin for patients with cancer--meta-analysis based on individual patient data. 1 0 1
5503 30779870 Effectiveness of provision of animal-source foods for supporting optimal growth and development in children 6 to 59 months of age. 2 0 1
5477 20927762 Oral budesonide for induction of remission in ulcerative colitis. 1 0 1
5478 17054217 Probiotics for maintenance of remission in Crohn's disease. 1 0 1
5480 28103638 Music interventions for acquired brain injury. 1 0 1
5481 11687079 Pharmacological treatment for aphasia following stroke. 1 0 1
5483 23799617 Transcranial direct current stimulation (tDCS) for improving aphasia in patients after stroke. 2 0 1
5485 16625539 Amantadine and rimantadine for influenza A in adults. 1 0 1
5486 25415374 Amantadine and rimantadine for influenza A in children and the elderly. 1 0 1
5487 15266442 Amantadine and rimantadine for preventing and treating influenza A in adults. 1 0 1
5789 16855954 Benzodiazepines for neuroleptic-induced tardive dyskinesia. 1 0 1
5790 10796323 Diltiazem, nifedipine, nimodipine or verapamil for neuroleptic-induced tardive dyskinesia. 1 0 1
5791 25654768 Fluphenazine decanoate (depot) and enanthate for schizophrenia. 2 0 1
5782 25866139 Warming of intravenous and irrigation fluids for preventing inadvertent perioperative hypothermia. 1 0 1
5767 10796427 Cooling therapy for acute stroke. 1 0 1
5780 15495003 Therapeutic hypothermia for head injury. 1 0 1
5768 16437469 Decompressive craniectomy for the treatment of refractory high intracranial pressure in traumatic brain injury. 1 0 1
5770 28933514 Hypothermia for traumatic brain injury. 1 0 1
5771 19370561 Hypothermia for traumatic head injury. 1 0 1
5772 11279752 Hypothermia to reduce neurological damage following coronary artery bypass surgery. 1 0 1
5773 25411963 Interventions for treating inadvertent postoperative hypothermia. 1 0 1
5774 15674932 Interventions to prevent hypothermia at birth in preterm and/or low birthweight babies. 1 0 1
5775 20238329 Interventions to prevent hypothermia at birth in preterm and/or low birthweight infants. 1 0 1
5776 27875631 Intravenous nutrients for preventing inadvertent perioperative hypothermia in adults. 1 0 1
5777 27552521 Kangaroo mother care to reduce morbidity and mortality in low birthweight infants. 1 0 1
5778 22161417 Light-emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates. 1 0 1
5769 17443543 Double wall versus single wall incubator for reducing heat loss in very low birth weight infants in incubators. 1 0 1
5805 17253480 Amantadine for fatigue in multiple sclerosis. 1 0 1
5806 14583932 Anti-spasticity agents for multiple sclerosis. 1 0 1
5807 19160231 Anticholinergics for urinary symptoms in multiple sclerosis. 1 0 1
5841 19588420 Treatment of seizures in multiple sclerosis. 1 0 1
5842 30246874 Vitamin D for the management of multiple sclerosis. 1 0 1
5843 22336858 Whole-body vibration training for patients with neurodegenerative disease. 2 0 1
5766 25739381 Chlorhexidine skin or cord care for prevention of mortality and infections in neonates. 1 0 1
5765 26256531 Alpha-2 adrenergic agonists for the prevention of shivering following general anaesthesia. 1 0 1
5764 27098439 Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults. 1 0 1
5801 15106155 Quetiapine for schizophrenia. 2 0 1
5792 21491376 Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia. 1 0 1
5794 22592725 Maintenance treatment with antipsychotic drugs for schizophrenia. 2 0 1
5795 12804390 Miscellaneous treatments for neuroleptic-induced tardive dyskinesia. 1 0 1
5796 29342497 Non-antipsychotic catecholaminergic drugs for antipsychotic-induced tardive dyskinesia. 1 0 1
5797 16437424 Non-neuroleptic catecholaminergic drugs for neuroleptic-induced tardive dyskinesia. 1 0 1
5798 12918000 Olanzapine alone or in combination for acute mania. 1 0 1
5799 25290157 Perphenazine versus low-potency first-generation antipsychotic drugs for schizophrenia. 2 0 1
5800 16855961 Polyunsaturated fatty acid supplementation for schizophrenia. 2 0 1
5802 17054149 Zotepine for schizophrenia. 2 0 1
5763 23152243 Surgery versus radical endotherapies for early cancer and high-grade dysplasia in Barrett's oesophagus. 3 0 1
5793 21975780 Interventions for disorders of eye movement in patients with stroke. 2 0 1
5803 15266528 Steroid hormones for contraception in men. 1 0 1
5781 24895945 Thermal insulation for preventing inadvertent perioperative hypothermia. 1 0 1
5779 27149645 Prophylactic barbiturate use for the prevention of morbidity and mortality following perinatal asphyxia. 2 0 1
5759 17054273 Weight reduction for primary prevention of stroke in adults with overweight or obesity. 2 0 1
5760 30556590 Workplace interventions for reducing sitting at work. 1 0 1
5761 15674952 Wound drainage for caesarean section. 2 0 1
5762 20464752 Surgery versus radical endotherapies for early cancer and high grade dysplasia in Barrett's oesophagus. 3 0 1
5703 24979199 Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission. 1 0 1
5734 23921458 In-work tax credits for families and their impact on health status in adults. 1 0 1
5735 22895964 Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people. 1 0 1
5209 28257555 Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults. 1 0 1
5211 17943872 Fish oil for induction of remission in ulcerative colitis. 2 0 1
5202 19821442 Pharmacological interventions to decrease blood loss and blood transfusion requirements for liver resection. 1 0 1
5164 23543551 Damage control surgery for abdominal trauma. 2 0 1
5189 28973845 Mesalamine (5-ASA) for the prevention of recurrent diverticulitis. 4 0 1
5187 23076884 Steroid sex hormones for lower limb atherosclerosis. 2 0 1
5166 30211952 Methods for blood loss estimation after vaginal birth. 1 0 1
5167 28945930 Plasma transfusions prior to lumbar punctures and epidural catheters for people with abnormal coagulation. 1 0 1
5168 29151811 Prophylactic plasma transfusion for patients undergoing non-cardiac surgery. 1 0 1
5169 26151108 Prothrombin complex concentrate for reversal of vitamin K antagonist treatment in bleeding and non-bleeding patients. 1 0 1
5170 26058967 Snake antivenom for snake venom induced consumption coagulopathy. 1 0 1
5171 21412912 Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion. 1 0 1
5172 25686465 Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding. 1 0 1
5173 27552162 Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding. 1 0 1
5175 24959692 Angioplasty versus bare metal stenting for superficial femoral artery lesions. 3 0 1
5188 29178125 Laparoscopic versus open resection for sigmoid diverticulitis. 2 0 1
5176 26023746 Angioplasty versus stenting for iliac artery lesions. 2 0 1
5178 23543518 Artichoke leaf extract for treating hypercholesterolaemia. 1 0 1
5179 23744539 Chinese herbal medicines for hypertriglyceridaemia. 1 0 1
5180 23934945 Cryoplasty for peripheral arterial disease. 1 0 1
5210 24817514 Antimicrobial prophylaxis for colorectal surgery. 1 0 1
5208 21901692 Antibiotic treatment for Clostridium difficile-associated diarrhea in adults. 2 0 1
5736 19160202 Interventions for treating obesity in children. 1 0 1
5207 30624763 Antiamoebic drugs for treating amoebic colitis. 1 0 1
5122 23076933 Interventions for preventing mastitis after childbirth. 1 0 1
5110 29663328 Gamma-aminobutyric acid agonists for antipsychotic-induced tardive dyskinesia. 2 0 1
5163 10796423 Rapid versus slow rate of advancement of feedings for promoting growth and preventing necrotizing enterocolitis in parenterally fed low-birth-weight infants. 1 0 1
5165 26171897 Fresh frozen plasma for cardiovascular surgery. 1 0 1
5191 21735382 Interventions for preventing lower limb soft-tissue running injuries. 1 0 1
5192 12519552 Interventions for treating melioidosis. 1 0 1
5193 19370675 Root coverage procedures for the treatment of localised recession-type defects. 1 0 1
5194 30277568 Root coverage procedures for treating localised and multiple recession-type defects. 1 0 1
5196 19821405 Cardiopulmonary interventions to decrease blood loss and blood transfusion requirements for liver resection. 1 0 1
5197 29630730 Glucocorticosteroid-free versus glucocorticosteroid-containing immunosuppression for liver transplanted patients. 1 0 1
5198 29473717 Interventions for paracetamol (acetaminophen) overdose. 1 0 1
5199 19160339 Ischaemic pre-conditioning for elective liver resections performed under vascular occlusion. 1 0 1
5200 19160340 Methods of vascular occlusion for elective liver resections. 2 0 1
5190 11686985 Interventions for preventing lower limb soft-tissue injuries in runners. 1 0 1
5201 19821445 Pharmacological interventions for ischaemia reperfusion injury in liver resection surgery performed under vascular control. 1 0 1
5203 19821421 Pharmacological interventions versus no pharmacological intervention for ischaemia reperfusion injury in liver resection surgery performed under vascular control. 1 0 1
5204 22419324 Techniques of flushing and reperfusion for liver transplantation. 1 0 1
5205 19160336 Vascular occlusion for elective liver resections. 1 0 1
5206 19160315 Cholecystectomy for gallbladder polyp. 1 0 1
5181 23633303 Garlic for peripheral arterial occlusive disease. 1 0 1
5182 23881650 Homocysteine lowering interventions for peripheral arterial disease and bypass grafts. 2 0 1
5183 24399686 Intravascular brachytherapy for peripheral vascular disease. 2 0 1
5184 10796489 Lipid-lowering for lower limb atherosclerosis. 1 0 1
5047 23824785 Omega-3 fatty acids for intermittent claudication. 2 0 1
5048 15846607 Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis. 2 0 1
5049 23235596 Percutaneous transluminal rotational atherectomy for coronary artery disease. 2 0 1
5050 24488616 Pharmacological interventions for hypertension in children. 3 0 1
5041 19160252 Pharmacotherapy and psychotherapy for body dysmorphic disorder. 1 0 1
5051 26270008 Preoperative statin therapy for patients undergoing cardiac surgery. 2 0 1
5029 22161420 Coenzyme Q10 for Parkinson's disease. 4 0 1
5027 14973963 Topical ointment for preventing infection in preterm infants. 1 0 1
5003 10796159 Oxytocin for prelabour rupture of membranes at or near term. 3 0 1
5004 25613573 Pneumococcal vaccination during pregnancy for preventing infant infection. 1 0 1
5006 10796171 Prostaglandins for prelabour rupture of membranes at or near term. 2 0 1
5007 25398160 Routine perineal shaving on admission in labour. 2 0 1
5008 21735400 Oral steroids for nasal polyps. 1 0 1
5011 26270434 Treatment for women with postpartum iron deficiency anaemia. 1 0 1
5012 24867876 Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection. 1 0 1
5013 29393511 Primaquine or other 8-aminoquinolines for reducing Plasmodium falciparum transmission. 2 0 1
5014 15266522 Albumin infusion for low serum albumin in preterm newborn infants. 3 0 1
5028 16034906 Volume-targeted versus pressure-limited ventilation in the neonate. 1 0 1
5015 20091562 Ethamsylate for the prevention of morbidity and mortality in preterm or very low birth weight infants. 1 0 1
5046 17943736 Lipid-lowering for peripheral arterial disease of the lower limb. 1 0 1
5045 28816346 Homocysteine-lowering interventions for preventing cardiovascular events. 2 0 1
5044 11279730 Exercise-based rehabilitation for coronary heart disease. 1 0 1
5033 11869612 Lubeluzole for acute ischaemic stroke. 1 0 1
5185 23824754 Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery. 1 0 1
5186 26148115 Psychosocial interventions for smoking cessation in patients with coronary heart disease. 2 0 1
5177 19370653 Angioplasty versus stenting for superficial femoral artery lesions. 2 0 1
5108 24595545 Family intervention (brief) for schizophrenia. 2 0 1
5107 15846598 Electroconvulsive therapy for schizophrenia. 3 0 1
5106 28613395 Clozapine dose for schizophrenia. 2 0 1
5031 15846748 Long-term non-pharmacological weight loss interventions for adults with prediabetes. 2 0 1
5032 10796194 Elective high frequency jet ventilation versus conventional ventilation for respiratory distress syndrome in preterm infants. 1 0 1
5034 14583925 Calcium channel blockers for acute traumatic brain injury. 1 0 1
5043 26730878 Exercise-based cardiac rehabilitation for coronary heart disease. 1 0 1
5035 23633351 Cholesterol-reducing agents for aneurysmal subarachnoid haemorrhage. 1 0 1
5036 23780732 Surgery for traumatic optic neuropathy. 2 0 1
5037 19821418 Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. 1 0 1
5038 23728640 Vaccines for women to prevent neonatal tetanus. 5 0 1
5039 11279766 Non-pharmacological therapies for dysphagia in Parkinson's disease. 2 0 1
5030 27374000 Rapid antigen detection test for group A streptococcus in children with pharyngitis. 1 0 1
5040 15495086 Pain relief for neonatal circumcision. 1 0 1
5042 24027118 Beta blockers for peripheral arterial disease. 2 0 1
5132 17054205 Tongxinluo (Tong xin luo or Tong-xin-luo) capsule for unstable angina pectoris. 1 0 1
5131 27226069 Routine invasive strategies versus selective invasive strategies for unstable angina and non-ST elevation myocardial infarction in the stent era. 2 0 1
5130 16856037 Puerarin injection for unstable angina pectoris. 1 0 1
5756 21975777 Transtheoretical model for dietary and physical exercise modification in weight loss management for overweight and obese adults. 1 0 1
5705 30620055 Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria. 1 0 1
5708 24740584 Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings. 1 0 1
5709 12076440 Routine anticonvulsants for treating cerebral malaria. 1 0 1
5710 26954551 Subsidising artemisinin-based combination therapy in the private retail sector. 1 0 1
5711 16437507 Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria. 1 0 1
5713 15846723 Unit-dose packaged drugs for treating malaria. 1 0 1
5714 18646154 Uterine massage for preventing postpartum haemorrhage. 1 0 1
5716 17054280 Vaccines for preventing malaria (pre-erythrocytic). 1 0 1
5718 12535387 Vaccines for preventing malaria. 1 0 1
5719 24826920 Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years of age. 1 0 1
5720 12076496 Advice on low-fat diets for obesity. 1 0 1
5721 28513831 Avoidance versus use of neuromuscular blocking agents for improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents. 1 0 1
5722 18646097 Chitosan for overweight or obesity. 1 0 1
5723 24293292 Chromium picolinate supplementation for overweight or obese adults. 1 0 1
5724 23633380 Deflation of gastric band balloon in pregnancy for improving outcomes. 1 0 1
5725 23881656 Diet or exercise, or both, for weight reduction in women after childbirth. 1 0 1
5726 28639320 Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to 17 years. 1 0 1
5727 26961576 Diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool children up to the age of 6 years. 1 0 1
5728 26171908 Directed preconception health programs and interventions for improving pregnancy outcomes for women who are overweight or obese. 1 0 1
5704 25693791 Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission. 1 0 1
5730 29974953 Effects of total fat intake on bodyweight in children. 1 0 1
5731 17054187 Exercise for overweight or obesity. 1 0 1
5745 29482264 Nutritional labelling for healthier food or non-alcoholic drink purchasing and consumption. 1 0 1
5737 29190418 Interventions to change the behaviour of health professionals and the organisation of care to promote weight reduction in children and adults with overweight or obesity. 1 0 1
5738 20238311 Interventions to change the behaviour of health professionals and the organisation of care to promote weight reduction in overweight and obese people. 1 0 1
5739 17253531 Intragastric balloon for obesity. 1 0 1
5740 11279768 Lifestyle modification for obstructive sleep apnoea. 1 0 1
5741 15846698 Long-term non-pharmacologic weight loss interventions for adults with type 2 diabetes. 1 0 1
5742 15266516 Long-term pharmacotherapy for obesity and overweight. 1 0 1
5733 11405970 Improving health professionals' management and the organisation of care for overweight and obese people. 1 0 1
5743 17636786 Low glycaemic index or low glycaemic load diets for overweight and obesity. 1 0 1
5746 26690844 Parent-only interventions for childhood overweight or obesity in children aged 5 to 11 years. 1 0 1
5732 27537097 Hormonal contraceptives for contraception in overweight or obese women. 1 0 1
5747 29499084 Physical activity, diet and other behavioural interventions for improving cognition and school achievement in children and adolescents with obesity or overweight. 1 0 1
5748 15846683 Psychological interventions for overweight or obesity. 1 0 1
5749 20238349 Service organisation for the secondary prevention of ischaemic heart disease in primary care. 1 0 1
5750 27699761 Strategies to improve the implementation of healthy eating, physical activity and obesity prevention policies, practices or programmes within childcare services. 1 0 1
5751 30480770 Strategies to improve the implementation of workplace-based policies or practices targeting tobacco, alcohol, diet, physical activity and obesity. 1 0 1
5752 16235331 Surgery for morbid obesity. 1 0 1
5753 26104326 Surgery for the treatment of obesity in children and adolescents. 1 0 1
5744 21249647 Multiple risk factor interventions for primary prevention of coronary heart disease. 1 0 1
5729 26250104 Effects of total fat intake on body weight. 1 0 1
5865 23152268 Antibiotics for uncomplicated diverticulitis. 1 0 1
5129 11687143 Platelet glycoprotein IIb/IIIa blockers for percutaneous coronary revascularization, and unstable angina and non-ST-segment elevation myocardial infarction. 2 0 1
5423 22972121 Acupuncture for mumps in children. 1 0 1
5162 17943881 Protein containing synthetic surfactant versus animal derived surfactant extract for the prevention and treatment of respiratory distress syndrome. 1 0 1
5136 17943809 Azathioprine for multiple sclerosis. 2 0 1
5134 22071812 Preoperative hair removal to reduce surgical site infection. 1 0 1
5111 29368813 Selective noradrenaline reuptake inhibitors for schizophrenia. 2 0 1
5112 27120555 Self management interventions for type 2 diabetes in adult people with severe mental illness. 1 0 1
5113 18646098 Valproate for schizophrenia. 1 0 1
5114 17943861 Cryoplasty for peripheral vascular disease. 2 0 1
5115 30684445 Drug-eluting balloon angioplasty versus uncoated balloon angioplasty for the treatment of in-stent restenosis of the femoropopliteal arteries. 2 0 1
5116 17054136 Local oestrogen for vaginal atrophy in postmenopausal women. 1 0 1
5117 30350354 Oxcarbazepine versus phenytoin monotherapy for epilepsy: an individual participant data review. 2 0 1
5118 24609897 Sulthiame monotherapy for epilepsy. 2 0 1
5119 27922724 Antenatal breastfeeding education for increasing breastfeeding duration. 1 0 1
5135 17054210 Single versus double volume exchange transfusion in jaundiced newborn infants. 1 0 1
5121 10796083 Home-like versus conventional institutional settings for birth. 1 0 1
5123 25506813 Interventions for treating painful nipples among breastfeeding women. 1 0 1
5124 27351423 Treatments for breast engorgement during lactation. 1 0 1
5126 16856118 Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV-infection. 2 0 1
5127 30411789 Antiretroviral resistance testing in HIV-positive people. 1 0 1
5128 15674954 Percutaneous transluminal coronary angioplasty with stents versus coronary artery bypass grafting for people with stable angina or acute coronary syndromes. 1 0 1
5152 11405975 Delayed (>3 weeks) postnatal corticosteroids for chronic lung disease in preterm infants. 1 0 1
5161 10796424 Prophylactic nasal continuous positive airways pressure for preventing morbidity and mortality in very preterm infants. 1 0 1
5160 14973972 Oral immunoglobulin for preventing necrotizing enterocolitis in preterm and low birth-weight neonates. 1 0 1
5147 26611822 Prenatal interventions for congenital diaphragmatic hernia for improving outcomes. 2 0 1
5421 25549990 The emerging epidemic of endometrial cancer: Time to take action. 2 0 1
5138 27605387 GenoType® MTBDRsl assay for resistance to second-line anti-tuberculosis drugs. 2 0 1
5139 17943782 Anticholinergic drugs versus other medications for overactive bladder syndrome in adults. 1 0 1
5140 17054185 Anticholinergic drugs versus placebo for overactive bladder syndrome in adults. 1 0 1
5141 19370596 Sacral neuromodulation with implanted devices for urinary storage and voiding dysfunction in adults. 1 0 1
5142 22258963 Which anticholinergic drug for overactive bladder symptoms in adults. 1 0 1
5145 28892119 Prophylactic chemotherapy for hydatidiform mole to prevent gestational trophoblastic neoplasia. 1 0 1
5146 12137629 Late versus early surgical correction for congenital diaphragmatic hernia in newborn infants. 1 0 1
5150 19370625 Metformin treatment before and during IVF or ICSI in women with polycystic ovary syndrome. 1 0 1
5159 10796374 Minimal enteral nutrition for promoting feeding tolerance and preventing morbidity in parenterally fed infants. 1 0 1
5137 22972125 Chlorambucil for patients with primary biliary cirrhosis. 2 0 1
5151 11687093 Continuous positive airway pressure versus theophylline for apnea in preterm infants. 2 0 1
5153 10796252 Early postnatal (<96 hours) corticosteroids for preventing chronic lung disease in preterm infants. 1 0 1
5154 10796276 Early versus delayed initiation of progressive enteral feedings for parenterally fed low birth weight or preterm infants. 1 0 1
5155 10796202 Enteral antibiotics for preventing necrotising enterocolitis in low birthweight or preterm infants. 1 0 1
5156 11279690 Enteral antibiotics for preventing necrotizing enterocolitis in low birthweight or preterm infants. 1 0 1
5157 12804505 Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants. 1 0 1
5158 16625631 Intravenous in-line filters for preventing morbidity and mortality in neonates. 1 0 1
5519 25961741 Abdominal drainage versus no drainage post-gastrectomy for gastric cancer. 1 0 1
5516 29309720 Radical multimodality therapy for malignant pleural mesothelioma. 2 0 1
5018 21735396 Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants. 1 0 1
1188 22419313 Transcutaneous electric nerve stimulation (TENS) for cancer pain in adults. 1 0 1
1190 24919460 Trastuzumab-containing regimens for metastatic breast cancer. 4 0 1
1191 25032250 Treating metastatic breast cancer: the evidence for targeted therapy. 1 0 1
1192 29105051 Tumour bed boost radiotherapy for women after breast-conserving surgery. 1 0 1
1183 26058962 Taxane-containing regimens for metastatic breast cancer. 2 0 1
1193 22786517 Vascular-endothelial-growth-factor (VEGF) targeting therapies for endocrine refractory or resistant metastatic breast cancer. 2 0 1
1195 28045199 Yoga for improving health-related quality of life, mental health and cancer-related symptoms in women diagnosed with breast cancer. 2 0 1
1196 17054218 Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents. 1 0 1
1197 25267890 Interventions for obsessive compulsive symptoms in people with schizophrenia. 2 0 1
1198 17054260 Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders. 2 0 1
1199 17443583 Psychological treatments versus treatment as usual for obsessive compulsive disorder (OCD). 2 0 1
1201 18253995 Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD). 2 0 1
1202 12917964 Transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder. 1 0 1
1203 22419332 Tricyclic antidepressants for autism spectrum disorders (ASD) in children and adolescents. 2 0 1
1204 27378490 Active cycle of breathing technique for cystic fibrosis. 1 0 1
1194 24158902 Wound drainage after axillary dissection for carcinoma of the breast. 2 0 1
1182 15846659 Taxane containing regimens for metastatic breast cancer. 1 0 1
1181 24213953 Tamoxifen or letrozole versus standard methods for women with estrogen-receptor positive breast cancer undergoing oocyte or embryo cryopreservation in assisted reproduction. 1 0 1
1180 11279694 Tamoxifen for early breast cancer. 3 0 1
1155 23076939 Primary prophylactic colony-stimulating factors for the prevention of chemotherapy-induced febrile neutropenia in breast cancer patients. 2 0 1
1189 22513938 Trastuzumab containing regimens for early breast cancer. 2 0 1
1187 22786516 Toremifene versus tamoxifen for advanced breast cancer. 1 0 1
1329 26342714 Interventions for treating constipation in pregnancy. 1 0 1
1186 24832784 Topical agents and dressings for fungating wounds. 1 0 1
1332 23744562 Isoflavones for hypercholesterolaemia in adults. 1 0 1
1333 26778150 Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection. 2 0 1
1335 17054172 Laxatives for the management of constipation in palliative care patients. 1 0 1
1336 25967924 Laxatives for the management of constipation in people receiving palliative care. 1 0 1
1337 21249653 Laxatives or methylnaltrexone for the management of constipation in palliative care patients. 1 0 1
1338 26630349 Lifestyle interventions for the treatment of urinary incontinence in adults. 2 0 1
1339 28146271 Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain. 1 0 1
1340 23543553 Long-term effects of weight-reducing drugs in hypertensive patients. 2 0 1
1341 26934640 Long-term effects of weight-reducing drugs in people with hypertension. 4 0 1
1342 24957634 Maintenance treatments for opiate -dependent adolescents. 1 0 1
1343 24420006 Management of faecal incontinence and constipation in adults with central neurological diseases. 5 0 1
1344 10796584 Mecamylamine (a nicotine antagonist) for smoking cessation. 1 0 1
1345 22419330 Milnacipran for neuropathic pain and fibromyalgia in adults. 2 0 1
1268 30557452 Recombinant growth hormone therapy for cystic fibrosis in children and young adults. 1 0 1
1267 24941199 Psychological interventions for individuals with cystic fibrosis and their families. 1 0 1
1265 29537064 Preconception risk assessment for thalassaemia, sickle cell disease, cystic fibrosis and Tay-Sachs disease. 4 0 1
1264 30616300 Potentiators (specific therapies for class III and IV mutations) for cystic fibrosis. 2 0 1
1184 17943815 Taxanes for adjuvant treatment of early breast cancer. 1 0 1
1185 21563138 Timing of breast surgery in premenopausal breast cancer patients. 1 0 1
1156 26687844 Prophylactic antibiotics or G(M)-CSF for the prevention of infections and improvement of survival in cancer patients receiving myelotoxic chemotherapy. 5 0 1
1157 24609957 Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery. 1 0 1
1158 21069671 Prophylactic mastectomy for the prevention of breast cancer. 1 0 1
1159 23737397 Psychological interventions for women with metastatic breast cancer. 1 0 1
1243 23152214 Macrolide antibiotics for cystic fibrosis. 1 0 1
1244 30260472 Nebulised hypertonic saline for cystic fibrosis. 2 0 1
1245 23633344 Nebuliser systems for drug delivery in cystic fibrosis. 1 0 1
1246 23852992 Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis. 2 0 1
1247 26905631 Neuraminidase inhibitors for the treatment of influenza infection in people with cystic fibrosis. 3 0 1
1248 19160197 Newborn screening for cystic fibrosis. 1 0 1
1249 26730723 Omega-3 fatty acids for cystic fibrosis. 1 0 1
1240 30075058 Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis. 15 0 1
1250 28349527 Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. 1 0 1
1252 28470972 Oral calorie supplements for cystic fibrosis. 2 0 1
1253 27055154 Oral non-steroidal anti-inflammatory drug therapy for lung disease in cystic fibrosis. 1 0 1
1254 26649765 Oral steroids for long-term use in cystic fibrosis. 3 0 1
1255 28471492 Oscillating devices for airway clearance in people with cystic fibrosis. 1 0 1
1256 23888484 Oxygen therapy for cystic fibrosis. 1 0 1
1257 27439110 Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis. 1 0 1
1258 28795404 Palliative drug treatments for breathlessness in cystic fibrosis. 1 0 1
1260 21069703 Percutaneous lines for delivering intravenous antibiotics in people with cystic fibrosis. 1 0 1
1262 27654832 Pneumococcal vaccines for cystic fibrosis. 1 0 1
1251 27412131 Oral anti-pseudomonal antibiotics for cystic fibrosis. 1 0 1
1242 29253920 Long-acting inhaled bronchodilators for cystic fibrosis. 1 0 1
1241 26226131 Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis. 1 0 1
1210 28000919 Antibiotic treatment for nontuberculous mycobacteria lung infection in people with cystic fibrosis. 2 0 1
1172 22336846 Short and long term effects of tibolone in postmenopausal women. 2 0 1
1160 26017383 Psychological interventions for women with non-metastatic breast cancer. 2 0 1
1161 23152241 Psychosocial interventions to improve quality of life and emotional wellbeing for recently diagnosed cancer patients. 1 0 1
1162 12076497 Radiotherapy for early breast cancer. 1 0 1
1165 23450577 School-based physical activity programs for promoting physical activity and fitness in children and adolescents aged 6 to 18. 1 0 1
1167 10796760 Screening for colorectal cancer using the faecal occult blood test, hemoccult. 2 0 1
1169 30776132 Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer. 3 0 1
1170 17054248 Sequencing of chemotherapy and radiation therapy for early breast cancer. 1 0 1
1171 23633328 Sequencing of chemotherapy and radiotherapy for early breast cancer. 4 0 1
1173 27733017 Short-term and long-term effects of tibolone in postmenopausal women. 4 0 1
1206 29551015 Anti-IgE therapy for allergic bronchopulmonary aspergillosis in people with cystic fibrosis. 4 0 1
1174 19370586 Single agent versus combination chemotherapy for metastatic breast cancer. 2 0 1
1175 18254086 Specialist breast care nurses for supportive care of women with breast cancer. 1 0 1
1176 11279781 Strategies for increasing women participation in community breast cancer screening. 1 0 1
1177 30779124 Surgical interventions for the prevention or treatment of lymphoedema after breast cancer treatment. 2 0 1
1178 28837757 Systemic antibiotics for treating malignant wounds. 1 0 1
1179 11687148 Systemic therapy for treating locoregional recurrence in women with breast cancer. 1 0 1
1205 30676656 Airway clearance techniques for cystic fibrosis: an overview of Cochrane systematic reviews. 1 0 1
1374 17943807 Tegaserod for the treatment of irritable bowel syndrome and chronic constipation. 4 0 1
1331 25550190 Iron therapy in anaemic adults without chronic kidney disease. 3 0 1
1328 25425011 Interventions for the management of taste disturbances. 2 0 1
5506 17636817 Azathioprine for primary biliary cirrhosis. 1 0 1
1306 16235320 Chinese herbal medicine for schizophrenia. 2 0 1
1310 29864216 Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults. 2 0 1
1311 26184397 Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery. 3 0 1
1312 27087396 Daily iron supplementation for improving anaemia, iron status and health in menstruating women. 1 0 1
1313 18425954 Dopamine agonist therapy in early Parkinson's disease. 3 0 1
1314 27899001 Drug interventions for the treatment of obesity in children and adolescents. 2 0 1
1315 23757096 Drug treatment for faecal incontinence in adults. 2 0 1
1316 20614454 Evaluation of the efficacy and safety of adjuvant treatment to levodopa therapy in Parkinson s disease patients with motor complications. 3 0 1
1317 27727431 Fentanyl for neuropathic pain in adults. 3 0 1
1308 25234029 Codeine, alone and with paracetamol (acetaminophen), for cancer pain. 2 0 1
1318 24222383 Homeopathy for treatment of irritable bowel syndrome. 14 0 1
1295 29355886 Antidepressants for depression in adults with HIV infection. 2 0 1
1293 29084357 Adverse events associated with medium- and long-term use of opioids for chronic non-cancer pain: an overview of Cochrane Reviews. 4 0 1
1269 29797578 Respiratory muscle training for cystic fibrosis. 1 0 1
1270 25198249 Self-management education for cystic fibrosis. 1 0 1
1271 27629557 Singing as an adjunct therapy for children and adults with cystic fibrosis. 1 0 1
1272 20464761 Singing for children and adults with cystic fibrosis. 1 0 1
1273 27907224 Single versus combination intravenous anti-pseudomonal antibiotic therapy for people with cystic fibrosis. 1 0 1
1274 24788768 Single versus combination intravenous antibiotic therapy for people with cystic fibrosis. 1 0 1
1275 24715704 Sodium channel blockers for cystic fibrosis. 1 0 1
1309 15654707 Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer. 2 0 1
1296 29669175 Antidepressants for preventing postnatal depression. 1 0 1
1326 29260510 Interventions for managing taste disturbances. 1 0 1
1305 15495118 Catechol-O-methyltransferase inhibitors versus active comparators for levodopa-induced complications in Parkinson's disease. 2 0 1
1011 24788900 Accommodative intraocular lens versus standard monofocal intraocular lens implantation in cataract surgery. 2 0 1
1013 29669176 Anti-vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema. 2 0 1
1015 26250103 Anti-vascular endothelial growth factor for prevention of postoperative vitreous cavity haemorrhage after vitrectomy for proliferative diabetic retinopathy. 5 0 1
1016 25418485 Anti-vascular endothelial growth factor for proliferative diabetic retinopathy. 3 0 1
1017 25066789 Antimetabolites in cataract surgery to prevent failure of a previous trabeculectomy. 2 0 1
1019 22696336 Beta radiation for glaucoma surgery. 2 0 1
1020 29786830 Blue-light filtering intraocular lenses (IOLs) for protecting macular health. 2 0 1
1050 24474622 Phacoemulsification with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract. 1 0 1
1150 15266482 Platinum containing regimens for metastatic breast cancer. 2 0 1
1151 28643430 Platinum-containing regimens for metastatic breast cancer. 3 0 1
1154 17443564 Preoperative chemotherapy for women with operable breast cancer. 1 0 1
1297 24346956 Aripiprazole alone or in combination for acute mania. 3 0 1
1298 24151065 Aromatase inhibitors for uterine fibroids. 2 0 1
1299 25719451 As required versus fixed schedule analgesic administration for postoperative pain in children. 2 0 1
1300 11687154 Behavioural and cognitive interventions with or without other treatments for defaecation disorders in children. 1 0 1
1301 22161370 Behavioural and cognitive interventions with or without other treatments for the management of faecal incontinence in children. 1 0 1
1302 24668156 Biofeedback for treatment of chronic idiopathic constipation in adults. 2 0 1
1303 15846668 Bulking agents, antispasmodic and antidepressant medication for the treatment of irritable bowel syndrome. 2 0 1
1304 12076434 Buprenorphine for the management of opioid withdrawal. 2 0 1
1276 29684249 Standard (head-down tilt) versus modified (without head-down tilt) postural drainage in infants and young children with cystic fibrosis. 1 0 1
1277 28981972 Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis. 1 0 1
1294 26638213 Alprazolam for essential tremor. 2 0 1
1278 30480755 Timing of dornase alfa inhalation for cystic fibrosis. 1 0 1
1351 28683172 Opioids for cancer pain - an overview of Cochrane reviews. 2 0 1
1361 21975787 Pharmacologic treatment for memory disorder in multiple sclerosis. 3 0 1
1363 30132304 Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD). 4 0 1
1364 26695595 Probiotics for preventing urinary tract infections in adults and children. 3 0 1
1365 26695080 Probiotics for the prevention of pediatric antibiotic-associated diarrhea. 2 0 1
1366 26299888 Sacral nerve stimulation for faecal incontinence and constipation in adults. 1 0 1
1367 23744563 Selenium supplementation for Hashimoto's thyroiditis. 3 0 1
1368 23440848 Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia syndrome. 15 0 1
1369 20091591 Serotonin receptor antagonists for highly emetogenic chemotherapy in adults. 1 0 1
1370 29693719 Smectite for acute infectious diarrhoea in children. 1 0 1
1372 18843623 Surgery for complete rectal prolapse in adults. 3 0 1
1362 28116777 Pharmacological treatment for antipsychotic-related constipation. 1 0 1
1349 18425947 Mu-opioid antagonists for opioid-induced bowel dysfunction. 2 0 1
1348 29869799 Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care. 3 0 1
1347 19588396 Milnacipran versus other antidepressive agents for depression. 1 0 1
1322 24874470 Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain. 4 0 1
1323 22161444 Intermittent iron supplementation for improving nutrition and development in children under 12 years of age. 1 0 1
1324 30699468 Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women. 2 0 1
1325 22161448 Intermittent iron supplementation for reducing anaemia and its associated impairments in menstruating women. 2 0 1
1360 27737513 Pharmacologic interventions for treating phantom limb pain. 1 0 1
1359 28829910 Oxycodone for cancer-related pain. 3 0 1
1358 27531591 Osmotic and stimulant laxatives for the management of childhood constipation. 2 0 1
1292 28829533 Vitamin K supplementation for cystic fibrosis. 1 0 1
1281 26098667 Topical nasal steroids for treating nasal polyposis in people with cystic fibrosis. 1 0 1
1282 22592694 Totally implantable vascular access devices for cystic fibrosis. 1 0 1
1283 30052271 Treatment for chronic methicillin-sensitive Staphylococcus aureus pulmonary infection in people with cystic fibrosis. 1 0 1
1285 26298311 Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis. 1 0 1
1286 23771707 Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis.. 1 0 1
1288 30091146 Vitamin A and beta (β)-carotene supplementation for cystic fibrosis. 1 0 1
1289 24823814 Vitamin A supplementation for cystic fibrosis. 1 0 1
1291 28262916 Vitamin E supplementation in people with cystic fibrosis. 2 0 1
1279 28146603 Timing of hypertonic saline inhalation for cystic fibrosis. 1 0 1
1357 22592734 Oral traditional Chinese medication for adhesive small bowel obstruction. 2 0 1
1319 27727452 Hydromorphone for cancer pain. 2 0 1
1320 27216018 Hydromorphone for neuropathic pain in adults. 3 0 1
1321 17943840 Hypnotherapy for treatment of irritable bowel syndrome. 2 0 1
1352 23986501 Opioids for neuropathic pain. 1 0 1
1353 27355187 Opioids for restless legs syndrome. 17 0 1
1354 27030166 Opioids for the palliation of refractory breathlessness in adults with advanced disease and terminal illness. 1 0 1
1355 24990381 Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors. 1 0 1
1356 26403220 Oral tapentadol for cancer pain. 2 0 1
1239 30030966 Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis. 1 0 1
1238 23450608 Interventions for the eradication of methicillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis. 1 0 1
1237 24338214 Interventions for promoting physical activity in people with cystic fibrosis. 2 0 1
5608 12804463 Folate for depressive disorders. 1 0 1
5612 20091506 Caffeine versus theophylline for apnea in preterm infants. 1 0 1
5613 11034672 Doxapram versus methylxanthine for apnea in preterm infants. 1 0 1
5614 23450573 Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome. 1 0 1
5603 23633305 Prostanoids for intermittent claudication. 1 0 1
5530 30320433 Exercise for reducing falls in people living with and beyond cancer. 1 0 1
5529 25424884 Exercise for cancer cachexia in adults. 1 0 1
5528 28577308 Empirical antibiotics targeting gram-positive bacteria for the treatment of febrile neutropenic patients with cancer. 1 0 1
5451 24752987 Higher versus lower protein intake in formula-fed low birth weight infants. 2 0 1
5452 10796869 Protein restriction for diabetic renal disease. 1 0 1
5453 29620795 Alpha-blockers as medical expulsive therapy for ureteral stones. 1 0 1
5454 22336806 Fluids and diuretics for acute ureteric colic. 1 0 1
5455 23235617 Manipulative therapies for infantile colic. 1 0 1
5456 23633323 Massage for promoting mental and physical health in typically developing infants under the age of six months. 1 0 1
5457 17054233 Massage intervention for promoting mental and physical health in infants aged under six months. 1 0 1
5458 15846699 Nonsteroidal anti-inflammatory drugs (NSAIDs) versus opioids for acute renal colic. 1 0 1
5459 27631535 Pain-relieving agents for infantile colic. 1 0 1
5450 21563146 Mental practice for treating upper extremity deficits in individuals with hemiparesis after stroke. 2 0 1
5461 25464360 Antidepressants for people with epilepsy and depression. 3 0 1
5463 29320603 Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children. 1 0 1
5610 10796246 Iron and folate supplementation in pregnancy. 2 0 1
5607 30734919 Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents. 1 0 1
1211 27415821 Antibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis. 1 0 1
5606 10796571 Vitamin E for intermittent claudication. 1 0 1
5642 16235412 Artemether-lumefantrine (six-dose regimen) for treating uncomplicated falciparum malaria. 1 0 1
5643 12804451 Artemether-lumefantrine for treating uncomplicated falciparum malaria. 1 0 1
5631 17443530 Bed rest for acute uncomplicated myocardial infarction. 1 0 1
5591 25358850 Cilostazol for intermittent claudication. 1 0 1
5617 21154343 Methylxanthine treatment for apnoea in preterm infants. 1 0 1
5615 23235664 Green tea for weight loss and weight maintenance in overweight or obese adults. 2 0 1
5593 29518253 Endovascular revascularisation versus conservative management for intermittent claudication. 1 0 1
5594 20091540 Endovascular stents for intermittent claudication. 1 0 1
5595 29278423 Exercise for intermittent claudication. 1 0 1
5596 23744597 Ginkgo biloba for intermittent claudication. 1 0 1
5597 22786478 Intravenous naftidrofuryl for critical limb ischaemia. 1 0 1
5598 25525690 Local intramuscular transplantation of autologous mononuclear cells for critical lower limb ischaemia. 1 0 1
5599 24993079 Modes of exercise training for intermittent claudication. 1 0 1
5600 23235580 Naftidrofuryl for intermittent claudication. 1 0 1
5601 27021597 Padma 28 for intermittent claudication. 1 0 1
5616 11686952 Methylxanthine treatment for apnea in preterm infants. 1 0 1
5602 26417854 Pentoxifylline for intermittent claudication. 1 0 1
5604 29627967 Supervised exercise therapy versus home-based exercise therapy versus walking advice for intermittent claudication. 1 0 1
5605 23970372 Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication. 1 0 1
5464 21975743 Evening versus morning dosing regimen drug therapy for hypertension. 2 0 1
5465 15106262 Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings. 1 0 1
5466 16856052 Magnesium supplementation for the management of essential hypertension in adults. 2 0 1
5467 28406263 Pharmacotherapy for hyperuricemia in hypertensive patients. 2 0 1
5439 27168518 Interventions for treating hyperemesis gravidarum. 1 0 1
5440 25749632 Perphenazine for schizophrenia. 2 0 1
5442 27437615 Percutaneous techniques versus surgical techniques for tracheostomy. 1 0 1
5443 12917913 Local treatments for cutaneous warts. 1 0 1
5444 26728940 Medical and surgical interventions for the treatment of usual-type vulval intraepithelial neoplasia. 1 0 1
5445 21491403 Medical interventions for high grade vulval intraepithelial neoplasia. 1 0 1
5435 12137689 Tissue adhesives for traumatic lacerations in children and adults. 1 0 1
5474 26039678 Budesonide for induction of remission in Crohn's disease. 1 0 1
5475 11686966 Enteral nutritional therapy for inducing remission of Crohn's disease. 1 0 1
5476 25157445 Methotrexate for maintenance of remission in Crohn's disease. 1 0 1
5507 22259000 Bezafibrate for primary biliary cirrhosis. 1 0 1
5508 15106254 Colchicine for primary biliary cirrhosis. 1 0 1
5509 17636804 Cyclosporin A for primary biliary cirrhosis. 1 0 1
5510 15495127 D-penicillamine for primary biliary cirrhosis. 1 0 1
5511 20464729 Methotrexate for primary biliary cirrhosis. 1 0 1
5512 23794285 Interventions for treating cholestasis in pregnancy. 1 0 1
5513 30845364 Intralesional treatment versus wide resection for central low-grade chondrosarcoma of the long bones. 1 0 1
5514 23440800 Combination chemotherapy for primary treatment of high-risk gestational trophoblastic tumour. 1 0 1
5515 17253564 Pemetrexed disodium in combination with cisplatin versus other cytotoxic agents or supportive care for the treatment of malignant pleural mesothelioma. 1 0 1
5438 19370692 Chlorpromazine dose for people with schizophrenia. 1 0 1
5437 17943771 Bromocriptine versus levodopa in early Parkinson's disease. 2 0 1
5436 19821375 Aripiprazole versus other atypical antipsychotics for schizophrenia. 1 0 1
5425 27074283 Infraorbital nerve block for postoperative pain following cleft lip repair in children. 1 0 1
5468 20687095 Spironolactone for hypertension. 2 0 1
5469 26423208 Newborn screening for homocystinuria. 1 0 1
5471 30556580 Treatment for Buruli ulcer: the long and winding road to antimicrobials-first. 1 0 1
5472 11687082 Interventions for treating cholestasis in pregnancy. 1 0 1
5462 25300175 Antiepileptic drugs for the primary and secondary prevention of seizures in viral encephalitis. 1 0 1
5473 30912847 Biomedical risk assessment as an aid for smoking cessation. 2 0 1
5449 26446577 Constraint-induced movement therapy for upper extremities in people with stroke. 2 0 1
5446 26284429 Medical interventions for high-grade vulval intraepithelial neoplasia. 1 0 1
5426 29518252 Interventions for autumn exacerbations of asthma in children. 2 0 1
5434 17943839 Self-management education programmes by lay leaders for people with chronic conditions. 1 0 1
5427 22972071 Interventions for recurrent idiopathic epistaxis (nosebleeds) in children. 1 0 1
5428 27033333 Interventions for treating ankle fractures in children. 1 0 1
5429 28177515 Methadone for cancer pain. 2 0 1
5430 23740539 Multidisciplinary rehabilitation following botulinum toxin and other focal intramuscular treatment for post-stroke spasticity. 2 0 1
5431 16625614 Music for pain relief. 1 0 1
5432 24343768 Nerve blocks for initial pain management of femoral fractures in children. 1 0 1
5433 19160206 Nursing record systems: effects on nursing practice and healthcare outcomes. 1 0 1
5447 24898010 Photodynamic therapy for recurrent respiratory papillomatosis. 2 0 1
5641 16625646 Artemether-lumefantrine (four-dose regimen) for treating uncomplicated falciparum malaria. 1 0 1
5640 25209020 Artemether for severe malaria. 1 0 1
5638 12804382 Amodiaquine for treating malaria. 1 0 1
5587 24801382 Anticoagulants (heparin, low molecular weight heparin and oral anticoagulants) for intermittent claudication. 1 0 1
3383 23450548 Pessaries (mechanical devices) for pelvic organ prolapse in women. 1 0 1
3658 10796666 Domicilary oxygen for chronic obstructive pulmonary disease. 1 0 1
5556 30784058 Systemic corticosteroids for the management of cancer-related breathlessness (dyspnoea) in adults. 1 0 1
5557 28510996 Tramadol with or without paracetamol (acetaminophen) for cancer pain. 1 0 1
5559 22161381 Oral rehydration salt solution for treating cholera: ≤ 270 mOsm/L solutions vs ≥ 310 mOsm/L solutions. 1 0 1
5561 27959472 Polymer-based oral rehydration solution for treating acute watery diarrhoea. 1 0 1
5562 10796624 Rice-based oral rehydration solution for treating diarrhoea. 1 0 1
5563 11034693 Vaccines for preventing cholera. 1 0 1
5565 23828581 Vaccines for preventing enterotoxigenic Escherichia coli (ETEC) diarrhoea. 1 0 1
5568 11687023 Antivirals for the common cold. 1 0 1
5569 17253524 Chinese medicinal herbs for the common cold. 1 0 1
5555 28429473 Surgery for limited-stage small-cell lung cancer. 2 0 1
5575 22336807 Oral antihistamine-decongestant-analgesic combinations for the common cold. 1 0 1
5580 15495097 HMG CoA reductase inhibitors (statins) for dialysis patients. 1 0 1
5581 23152216 Horse chestnut seed extract for chronic venous insufficiency. 1 0 1
5582 24127117 Non-pharmacological interventions for preventing venous insufficiency in a standing worker population. 1 0 1
5583 26889740 Oral aspirin for treating venous leg ulcers. 1 0 1
5584 22895941 Phlebotonics for haemorrhoids. 1 0 1
5585 27048768 Phlebotonics for venous insufficiency. 1 0 1
3656 28535331 Computer and mobile technology interventions for self-management in chronic obstructive pulmonary disease. 2 0 1
1209 26789750 Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation. 1 0 1
1236 29894558 Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis. 17 0 1
1223 30187450 Dornase alfa for cystic fibrosis. 1 0 1
1212 27820955 Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis. 3 0 1
1213 21154377 Antioxidant micronutrients for lung disease in cystic fibrosis. 1 0 1
1215 25064192 Appetite stimulants for people with cystic fibrosis. 1 0 1
1216 28102546 Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic fibrosis. 2 0 1
1217 28984368 Autogenic drainage for airway clearance in cystic fibrosis. 1 0 1
1219 30221745 Bronchoscopy-guided antimicrobial therapy for cystic fibrosis. 1 0 1
1221 28628280 Combination antimicrobial susceptibility testing for acute exacerbations in chronic infection of Pseudomonas aeruginosa in cystic fibrosis. 1 0 1
1222 30070364 Correctors (specific therapies for class II CFTR mutations) for cystic fibrosis. 1 0 1
1224 27546383 Drug therapies for reducing gastric acidity in people with cystic fibrosis. 2 0 1
1235 24258092 Inspiratory muscle training for cystic fibrosis. 1 0 1
1225 27582394 Duration of intravenous antibiotic therapy in people with cystic fibrosis. 2 0 1
1226 22786481 Elective versus symptomatic intravenous antibiotic therapy for cystic fibrosis. 1 0 1
1227 25854213 Enteral tube feeding for cystic fibrosis. 1 0 1
1228 27804115 Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis. 1 0 1
1229 26671062 Home versus hospital intravenous antibiotic therapy for cystic fibrosis. 1 0 1
1230 29921013 Immunosuppressive drug therapy for preventing rejection following lung transplantation in cystic fibrosis. 3 0 1
1231 29607494 Inhaled anti-pseudomonal antibiotics for long-term therapy in cystic fibrosis. 1 0 1
1233 30376155 Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis. 1 0 1
5586 27914110 Physical exercise for the treatment of non-ulcerated chronic venous insufficiency. 1 0 1
5588 22895926 Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment. 1 0 1
5637 24156098 Oxygen therapy in acute myocardial infarction – good or bad? 1 0 1
5577 28516442 Vaccines for the common cold. 1 0 1
5551 27727451 Postoperative radiotherapy for non-small cell lung cancer. 2 0 1
5542 30246876 Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults. 1 0 1
5531 30741408 Exercise training for advanced lung cancer. 2 0 1
5590 28368090 Bypass surgery for chronic lower limb ischaemia. 1 0 1
5592 18254032 Cilostazol for peripheral arterial disease. 1 0 1
5619 11687065 Prophylactic caffeine to prevent postoperative apnea following general anesthesia in preterm infants. 1 0 1
5620 10796361 Prophylactic methylxanthine for preventing of apnea in preterm infants. 1 0 1
5622 10796415 Assertive community treatment for people with severe mental disorders. 1 0 1
5623 10796288 Case management for people with severe mental disorders. 1 0 1
5624 26384252 Consultation liaison in primary care for people with mental disorders. 1 0 1
5625 24723301 Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with depression. 1 0 1
5627 24030739 Supported employment for adults with severe mental illness. 1 0 1
5628 17054130 Supported housing for people with severe mental disorders. 1 0 1
5629 28677828 Vortioxetine for depression in adults. 2 0 1
5618 10796287 Postoperative caffeine for preventing apnea in preterm infants. 1 0 1
5630 25985145 Adenosine and verapamil for no-reflow during primary percutaneous coronary intervention in people with acute myocardial infarction. 1 0 1
5633 18425903 Danshen (Chinese medicinal herb) preparations for acute myocardial infarction. 1 0 1
5634 23728682 Granulocyte colony stimulating factor therapy for acute myocardial infarction. 1 0 1
5636 21833929 Oxygen therapy in acute myocardial infarction -- too much of a good thing? 1 0 1
5550 27486906 Platinum-induced hearing loss after treatment for childhood cancer. 1 0 1
5549 27030386 Physical exercise training interventions for children and young adults during and after treatment for childhood cancer. 1 0 1
5548 25789452 Perioperative enhanced recovery programmes for gynaecological cancer patients. 1 0 1
5537 29130474 Interventions for the reduction of prescribed opioid use in chronic non-cancer pain. 1 0 1
5589 23543509 Buflomedil for intermittent claudication. 2 0 1
5554 26121600 Spinal cord stimulation for cancer-related pain in adults. 1 0 1
5552 28708236 Psychosocial interventions for fatigue during cancer treatment with palliative intent. 1 0 1
5532 27223332 First-line treatment of advanced epidermal growth factor receptor (EGFR) mutation positive non-squamous non-small cell lung cancer. 2 0 1
5533 29084358 High-dose opioids for chronic non-cancer pain: an overview of Cochrane Reviews. 1 0 1
5534 25989380 Interventions for cough in cancer. 2 0 1
5535 27898175 Interventions for promoting participation in shared decision-making for children with cancer. 1 0 1
5536 26632766 Interventions for smoking cessation in people diagnosed with lung cancer. 2 0 1
5538 25918920 Laetrile treatment for cancer. 1 0 1
5547 29182797 Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer. 2 0 1
5539 27030300 Laparoscopic versus open gastrectomy for gastric cancer. 1 0 1
5540 27524661 Music interventions for improving psychological and physical outcomes in cancer patients. 1 0 1
5553 26544798 Screening for nasopharyngeal cancer. 1 0 1
5541 30840317 Non-invasive positive pressure ventilation for prevention of complications after pulmonary resection in lung cancer patients. 2 0 1
5543 28745394 Opioids for chronic non-cancer pain in children and adolescents. 1 0 1
5544 27105021 Oral morphine for cancer pain. 1 0 1
5545 28700092 Oral paracetamol (acetaminophen) for cancer pain. 1 0 1
5546 30887505 Outpatient treatment for people with cancer who develop a low-risk febrile neutropaenic event. 1 0 1
5017 27148674 Heparin for the prevention of intraventricular haemorrhage in preterm infants. 3 0 1
5019 23633310 Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. 1 0 1
6053 19160222 Orthotic devices after stroke and other non-progressive brain lesions. 1 0 1
6647 11869618 Vitamin K antagonists or low-molecular-weight heparin for the long term treatment of symptomatic venous thromboembolism. 1 0 1
6649 25271097 Electrotherapy modalities for adhesive capsulitis (frozen shoulder). 1 0 1
6664 23440787 Pressure-relieving interventions for treating diabetic foot ulcers. 1 0 1
6650 25157702 Manual therapy and exercise for adhesive capsulitis (frozen shoulder). 1 0 1
6653 23799857 Alginate dressings for healing diabetic foot ulcers. 1 0 1
6654 24242704 Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) in non surgical wounds. 1 0 1
6655 23076929 Autologous platelet-rich plasma for treating chronic wounds. 1 0 1
6656 26299991 Complex interventions for preventing diabetic foot ulceration. 1 0 1
6657 20091547 Debridement of diabetic foot ulcers. 1 0 1
6658 23740766 Foam dressings for healing diabetic foot ulcers. 1 0 1
6659 23955465 Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections. 1 0 1
6660 23922167 Hydrocolloid dressings for healing diabetic foot ulcers. 1 0 1
6661 23846869 Hydrogel dressings for healing diabetic foot ulcers. 1 0 1
6651 17054278 Oral steroids for adhesive capsulitis. 1 0 1
6703 26370268 Surgical fixation methods for tibial plateau fractures. 1 0 1
6704 27590275 Surgical interventions (microfracture, drilling, mosaicplasty, and allograft transplantation) for treating isolated cartilage defects of the knee in adults. 1 0 1
6705 27039329 Surgical versus conservative interventions for treating anterior cruciate ligament injuries. 1 0 1
6738 21901689 Non-invasive interventions for improving well-being and quality of life in patients with lung cancer. 1 0 1
6740 15846743 Prophylactic cranial irradiation for preventing brain metastases in patients undergoing radical treatment for non-small cell lung cancer. 1 0 1
6741 11406051 Radical radiotherapy for stage I/II non-small cell lung cancer in patients not sufficiently fit for or declining surgery (medically inoperable). 1 0 1
6648 18254123 Arthrographic distension for adhesive capsulitis (frozen shoulder). 1 0 1
6646 10796381 Thrombolysis (different doses, routes of administration and agents) for acute ischaemic stroke. 1 0 1
6680 11869668 Electromagnetic fields for the treatment of osteoarthritis. 1 0 1
6645 23543563 Stent graft types for endovascular repair of abdominal aortic aneurysms. 1 0 1
6666 26866804 Skin grafting and tissue replacement for treating foot ulcers in people with diabetes. 1 0 1
6686 12804510 Intensity of exercise for the treatment of osteoarthritis. 1 0 1
6688 20091582 Interventions to improve adherence to exercise for chronic musculoskeletal pain in adults. 1 0 1
6689 16625636 Intraarticular corticosteroid for treatment of osteoarthritis of the knee. 1 0 1
6690 10796460 Low level laser therapy (classes I, II and III) for the treatment of osteoarthritis. 1 0 1
6693 21901700 Patellar tendon versus hamstring tendon autograft for anterior cruciate ligament rupture in adults. 1 0 1
6694 16856020 Posterior versus lateral surgical approach for total hip arthroplasty in adults with osteoarthritis. 1 0 1
6695 19588334 Progressive resistance strength training for improving physical function in older adults. 1 0 1
6696 24114343 Retention versus sacrifice of the posterior cruciate ligament in total knee arthroplasty for treating osteoarthritis. 1 0 1
6699 24425500 Self-management education programmes for osteoarthritis. 1 0 1
6700 20091621 Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement. 1 0 1
6687 20824867 Interventions for treating osteoarthritis of the big toe joint. 1 0 1
6702 25702783 Surgery for thumb (trapeziometacarpal joint) osteoarthritis. 1 0 1
6665 16437516 Silver based wound dressings and topical agents for treating diabetic foot ulcers. 1 0 1
6663 10908550 Pressure relieving interventions for preventing and treating diabetic foot ulcers. 1 0 1
6641 10908501 Elastic compression stockings for prevention of deep vein thrombosis. 1 0 1
6642 12535463 Endovascular stents for intermittent claudication. 1 0 1
6643 18843725 Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-leg immobilization. 1 0 1
6644 24519736 Pressure-relieving devices for treating heel pressure ulcers. 1 0 1
6743 12076452 Second-line chemotherapy for non-small cell lung cancer. 1 0 1
6744 15674959 Surgery for early stage non-small cell lung cancer. 1 0 1
6745 29365347 Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases. 1 0 1
6746 26560739 Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis. 1 0 1
6715 30019463 Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing non-cardiac surgery. 1 0 1
6716 18843694 Dengzhanhua preparations for acute cerebral infarction. 1 0 1
6717 20166088 Tirilazad for aneurysmal subarachnoid haemorrhage. 1 0 1
6718 25692326 Pharmacological interventions for those who have sexually offended or are at risk of offending. 1 0 1
6719 15266545 Psychological interventions for those who have sexually offended or are at risk of offending. 1 0 1
6720 16855962 Neuraminidase inhibitors for preventing and treating influenza in healthy adults. 1 0 1
6721 16235308 Acyclovir for treating varicella in otherwise healthy children and adolescents. 1 0 1
6723 22696369 Mobile phone messaging for communicating results of medical investigations. 1 0 1
6724 11869607 Pre-conception and antenatal screening for the fragile site on the X-chromosome. 1 0 1
6725 25803792 Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes. 1 0 1
6726 14974046 Diazepam for treating tetanus. 1 0 1
6727 23728678 Umbilical cord antiseptics for preventing sepsis and death among newborns. 1 0 1
6728 24226506 Vitamin C for preventing and treating tetanus. 1 0 1
6729 23152201 Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. 1 0 1
6732 22696370 Chemotherapy for brain metastases from small cell lung cancer. 1 0 1
6733 10796867 Chemotherapy for non-small cell lung cancer. 1 0 1
6640 20393944 Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of venous thromboembolism following total hip or knee replacement. 1 0 1
6314 19821360 Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults. 1 0 1
6639 22071857 Compression stockings for the initial treatment of varicose veins in patients without venous ulceration. 1 0 1
6714 12519539 Calcium antagonists for aneurysmal subarachnoid haemorrhage. 1 0 1
6713 17054216 Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults. 1 0 1
6711 16625635 Viscosupplementation for the treatment of osteoarthritis of the knee. 1 0 1
6759 26214143 Selenium supplementation for critically ill adults. 1 0 1
6748 23076897 Combined spinal-epidural versus epidural analgesia in labour. 1 0 1
6749 17443509 Conjugate vaccines for preventing Haemophilus influenzae type B infections. 1 0 1
6737 17943880 Elemene for the treatment of lung cancer. 1 0 1
6750 16855979 Conjugate vaccines for preventing meningococcal C meningitis and septicaemia. 1 0 1
6753 12918010 Corticosteroids in acute bacterial meningitis. 1 0 1
6755 22786491 Intraventricular antibiotics for bacterial meningitis in neonates. 1 0 1
6756 23450595 Optimal timing for antiretroviral therapy initiation in patients with HIV infection and concurrent cryptococcal meningitis. 1 0 1
6758 15674874 Polysaccharide vaccines for preventing serogroup A meningococcal meningitis. 1 0 1
6760 10908535 Steroids for treating tuberculous meningitis. 1 0 1
6708 11687038 Therapeutic ultrasound for osteoarthritis of the knee. 1 0 1
6763 18843697 Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings. 1 0 1
6764 25504106 Vaginal chlorhexidine during labour to prevent early-onset neonatal group B streptococcal infection. 1 0 1
6765 21412905 Notification and support for people exposed to the risk of Creutzfeldt-Jakob disease (CJD) (or other prion diseases) through medical treatment (iatrogenically). 1 0 1
6752 25687750 Corticosteroids for parasitic eosinophilic meningitis. 1 0 1
6736 15674960 Early versus late chest radiotherapy for limited stage small cell lung cancer. 1 0 1
6735 23076895 Drugs for preventing lung cancer in healthy people. 1 0 1
6734 24282143 Chemotherapy versus best supportive care for extensive small cell lung cancer. 1 0 1
6706 14974064 Surgical versus non-surgical treatment for acute anterior shoulder dislocation. 1 0 1
6683 12918008 Exercise for osteoarthritis of the hip or knee. 1 0 1
6679 24515444 Diacerein for osteoarthritis. 1 0 1
6356 15106221 Iodine supplementation for preventing iodine deficiency disorders in children. 1 0 1
6330 28099988 Exercise-based rehabilitation programmes for pulmonary hypertension. 2 0 1
6332 21069698 Milrinone for persistent pulmonary hypertension of the newborn. 2 0 1
6333 15846646 Prostacyclin for pulmonary hypertension in adults. 2 0 1
6334 28777888 Sildenafil for pulmonary hypertension in neonates. 2 0 1
6335 15495058 Sildenafil for pulmonary hypertension. 2 0 1
6336 28379619 Blood pressure lowering efficacy of renin inhibitors for primary hypertension. 2 0 1
6337 19821413 Interventions for central giant cell granuloma (CGCG) of the jaws. 1 0 1
6328 24887213 Anticoagulation therapy versus placebo for pulmonary hypertension. 2 0 1
6366 10796127 Human chorionic gonadotrophin for recurrent miscarriage. 1 0 1
6367 20464754 Human chorionic gonadotrophin for threatened miscarriage. 1 0 1
6368 25331518 Immunotherapy for recurrent miscarriage. 1 0 1
6400 23888424 Gabapentin add-on for drug-resistant partial epilepsy. 1 0 1
6401 10796785 Gabapentin for drug-resistant partial epilepsy. 1 0 1
6403 28675262 Intravenous immunoglobulins for epilepsy. 1 0 1
6405 12917915 Ketogenic diet for epilepsy. 1 0 1
6407 26077821 Lacosamide add-on therapy for partial epilepsy. 1 0 1
6408 16437428 Lamotrigine versus carbamazepine monotherapy for epilepsy. 1 0 1
6409 29952431 Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. 1 0 1
6410 11279737 Levetiracetam add-on for drug-resistant localization related (partial) epilepsy. 1 0 1
6411 26661741 Losigamone add-on therapy for partial epilepsy. 1 0 1
6331 17636807 Magnesium sulfate for persistent pulmonary hypertension of the newborn. 2 0 1
6329 27535894 Endothelin receptor antagonists for persistent pulmonary hypertension in term and late preterm infants. 2 0 1
6678 22972114 Cryotherapy following total knee replacement. 1 0 1
6326 15106169 Written individualised management plans for asthma in children and adults. 1 0 1
6359 15846669 Bed rest during pregnancy for preventing miscarriage. 1 0 1
6361 26760986 Chinese herbal medicines for unexplained recurrent miscarriage. 1 0 1
6362 24068368 Combined oestrogen and progesterone for preventing miscarriage. 1 0 1
6363 22419288 Expectant care versus surgical treatment for miscarriage. 1 0 1
6364 22419336 Follow-up for improving psychological well being for women after a miscarriage. 1 0 1
6353 12137681 Iodised salt for preventing iodine deficiency disorders. 2 0 1
6365 23440828 Human chorionic gonadotrophin (hCG) for preventing miscarriage. 1 0 1
6340 22161430 Computer-assisted versus oral-and-written dietary history taking for diabetes mellitus. 1 0 1
6338 26998683 Exercise-based cardiac rehabilitation for adults after heart valve surgery. 1 0 1
6315 27616040 Tailoring asthma therapies using FeNO: can a new objective measure help more people to gain control and reduce over-treatment? 1 0 1
6316 20927763 Telehealthcare for asthma. 1 0 1
6317 27582089 Vilanterol and fluticasone furoate for asthma. 1 0 1
6318 24154977 Vitamin C for asthma and exercise-induced bronchoconstriction. 1 0 1
6321 24936673 Vitamins C and E for asthma and exercise-induced bronchoconstriction. 1 0 1
6322 25032820 Water-based exercise for adults with asthma. 1 0 1
6323 21563151 Workplace interventions for treatment of occupational asthma. 1 0 1
6324 16856090 Written action plans for asthma in children. 1 0 1
6325 24842151 Written emotional disclosure for asthma. 1 0 1
6339 15674916 'Human' insulin versus animal insulin in people with diabetes mellitus. 1 0 1
6399 28718506 Felbamate as an add-on therapy for refractory partial epilepsy. 1 0 1
6413 26198593 Neuropsychological and psychological interventions for people with newly diagnosed epilepsy. 1 0 1
6415 26355236 Non-pharmacological interventions for people with epilepsy and intellectual disabilities. 1 0 1
6416 10908522 Oxcarbazepine add-on for drug-resistant partial epilepsy. 1 0 1
6386 12076427 Carbamazepine versus phenytoin monotherapy for epilepsy. 1 0 1
6387 26842929 Care delivery and self management strategies for adults with epilepsy. 1 0 1
6388 26695883 Care delivery and self management strategies for children with epilepsy. 1 0 1
6389 18254097 Care delivery and self-management strategies for adults with epilepsy. 1 0 1
6390 29493780 Care delivery and self-management strategies for children with epilepsy. 1 0 1
6391 18425899 Clobazam as an add-on in the management of refractory epilepsy. 1 0 1
6392 29717488 Clonazepam add-on therapy for refractory epilepsy in adults and children. 1 0 1
6393 15266543 Common antiepileptic drugs in pregnancy in women with epilepsy. 1 0 1
6394 25190506 Comparison of antiepileptic drugs, no treatment, or placebo for children with benign epilepsy with centro temporal spikes. 1 0 1
6395 26086765 Corticosteroids including ACTH for childhood epilepsy other than epileptic spasms. 1 0 1
6532 16625607 Aripiprazole for schizophrenia. 1 0 1
6534 18254078 Atypical antipsychotics for people with both schizophrenia and depression. 1 0 1
6535 17943922 Ayurvedic medicine for schizophrenia. 1 0 1
6536 15846648 Benperidol for schizophrenia. 1 0 1
6668 28613416 Topical antimicrobial agents for treating foot ulcers in people with diabetes. 1 0 1
6669 11279736 Topical negative pressure for treating chronic wounds. 1 0 1
6670 20238345 Topical silver for preventing wound infection. 1 0 1
6671 24715679 Type of incision for below knee amputation. 1 0 1
6675 27374001 Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve function after hip arthroplasty. 1 0 1
6385 12535420 Carbamazepine versus phenobarbitone monotherapy for epilepsy. 1 0 1
6384 24595491 Cannabinoids for epilepsy. 1 0 1
6383 23543516 Calcium antagonists as an add-on therapy for drug-resistant epilepsy. 1 0 1
6398 25036694 Felbamate as an add-on therapy for refractory epilepsy. 1 0 1
6417 23728645 Oxcarbazepine versus phenytoin monotherapy for epilepsy. 1 0 1
6418 26259048 Pharmacological treatments for preventing epilepsy following traumatic head injury. 1 0 1
6419 27536971 Polyunsaturated fatty acid supplementation for drug-resistant epilepsy. 1 0 1
6420 18646164 Preconception counselling for women with epilepsy to reduce adverse pregnancy outcome. 1 0 1
6421 24623260 Pregabalin add-on for drug-resistant partial epilepsy. 1 0 1
6422 23076957 Pregabalin monotherapy for epilepsy. 1 0 1
6424 29078005 Psychological treatments for people with epilepsy. 1 0 1
6414 17943860 Non-pharmacological interventions for epilepsy in people with intellectual disabilities. 1 0 1
6397 29067682 Eslicarbazepine acetate add-on for drug-resistant partial epilepsy. 1 0 1
6380 26648251 Surgery for Dupuytren's contracture of the fingers. 1 0 1
6396 11279739 Epilepsy clinics versus general neurology or medical clinics. 1 0 1
6369 20091626 Medical treatments for incomplete miscarriage (less than 24 weeks). 1 0 1
6370 28138973 Medical treatments for incomplete miscarriage. 1 0 1
6371 21678380 Metroplasty versus expectant management for women with recurrent miscarriage and a septate uterus. 1 0 1
6372 30298541 Progestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology. 1 0 1
6376 16034877 Uterine muscle relaxant drugs for threatened miscarriage. 1 0 1
6378 27356171 High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia. 1 0 1
6379 22161369 Interventions for involutional lower lid entropion. 1 0 1
6637 20091509 WITHDRAWAN. Antibiotic prophylaxis for cesarean section. 1 0 1
6565 23983042 Haloperidol dose for the acute phase of schizophrenia. 1 0 1
6566 18254045 Haloperidol versus chlorpromazine for schizophrenia. 1 0 1
6033 23728680 Interventions for preventing falls in people after stroke. 1 0 1
6035 28535332 Interventions for treating anxiety after stroke. 1 0 1
6022 22592740 Inspiratory muscle training for the recovery of function after stroke. 1 0 1
6037 21975779 Interventions for visual field defects in patients with stroke. 1 0 1
6009 22161410 Edaravone for acute ischaemic stroke. 1 0 1
6007 17636684 Dipyridamole for preventing stroke and other vascular events in patients with vascular disease. 2 0 1
5985 19370555 Anticoagulants for preventing recurrence following presumed non-cardioembolic ischaemic stroke or transient ischaemic attack. 1 0 1
5986 24464793 Antiepileptic drugs for the primary and secondary prevention of seizures after stroke. 1 0 1
5987 18646056 Antiplatelet therapy for acute ischaemic stroke. 1 0 1
5989 26193704 Buflomedil for acute ischaemic stroke. 1 0 1
5990 30758052 Calcium antagonists for acute ischemic stroke. 1 0 1
5991 28002636 Caregiver-mediated exercises for improving outcomes after stroke. 1 0 1
5993 20091603 Chuanxiong preparations for preventing stroke. 1 0 1
5994 18843695 Chuanxiong-type preparations for acute ischemic stroke. 1 0 1
5995 21249700 Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin. 1 0 1
6008 28703869 Early supported discharge services for people with acute stroke. 1 0 1
5996 28573757 Circuit class therapy for improving mobility after stroke. 1 0 1
5998 23633354 Cognitive rehabilitation for executive dysfunction in adults with stroke or other adult non-progressive acquired brain damage. 1 0 1
5999 27581994 Cognitive rehabilitation for memory deficits after stroke. 1 0 1
6000 17636703 Cognitive rehabilitation for memory deficits following stroke. 1 0 1
6034 20556766 Interventions for sensory impairment in the upper limb after stroke. 1 0 1
6031 26133313 Interventions for post-stroke fatigue. 1 0 1
6567 24842458 Horticultural therapy for schizophrenia. 1 0 1
6030 25387001 Interventions for improving upper limb function after stroke. 1 0 1
6638 25411554 Aspirin for primary prevention of coronary heart disease. 1 0 1
5867 15266501 Spinal cord stimulation for chronic pain. 1 0 1
6313 23633375 Swimming training for asthma in children and adolescents aged 18 years and under. 1 0 1
6310 24282112 Smartphone and tablet self management apps for asthma. 1 0 1
6011 18843735 Electromechanical and robot-assisted arm training for improving arm function and activities of daily living after stroke. 1 0 1
6012 22696362 Electromechanical and robot-assisted arm training for improving generic activities of daily living, arm function, and arm muscle strength after stroke. 1 0 1
6013 28488268 Electromechanical-assisted training for walking after stroke. 1 0 1
6014 17443550 EMG biofeedback for the recovery of motor function after stroke. 1 0 1
6015 22259001 External counterpulsation for acute ischaemic stroke. 1 0 1
6016 22419274 Fibrinogen depleting agents for acute ischaemic stroke. 1 0 1
6017 24609741 Glycoprotein IIb-IIIa inhibitors for acute ischaemic stroke. 1 0 1
6018 21678359 Hands-on therapy interventions for upper limb motor dysfunction following stroke. 1 0 1
6019 22592715 Home-based therapy programmes for upper limb functional recovery following stroke. 1 0 1
6010 30175845 Electromechanical and robot-assisted arm training for improving activities of daily living, arm function, and arm muscle strength after stroke. 1 0 1
6021 23152210 Information provision for stroke patients and their caregivers. 1 0 1
6024 22419333 Interventions for age-related visual problems in patients with stroke. 1 0 1
6026 23076886 Interventions for dysphagia and nutritional support in acute and subacute stroke. 1 0 1
6028 29734470 Interventions for improving modifiable risk factor control in the secondary prevention of stroke. 1 0 1
6029 24859467 Interventions for improving sit-to-stand ability following stroke. 1 0 1
6001 23813503 Cognitive rehabilitation for spatial neglect following stroke. 1 0 1
6002 23797623 Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke. 1 0 1
6003 19821326 Constraint-induced movement therapy for upper extremities in stroke patients. 1 0 1
6004 19160194 Cooling therapy for acute stroke. 1 0 1
6084 18425928 Therapy-based rehabilitation services for patients living at home more than one year after stroke. 1 0 1
6085 23728633 Thrombolysis (different doses, routes of administration and agents) for acute ischaemic stroke. 1 0 1
6087 26996760 Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive functioning, in people after stroke. 1 0 1
6088 24234980 Transcranial direct current stimulation (tDCS) for improving function and activities of daily living in patients after stroke. 1 0 1
6078 21833959 Statins for acute ischemic stroke. 1 0 1
6039 22972139 Iron chelators for acute stroke. 1 0 1
6065 18254067 Puerarin for acute ischaemic stroke. 1 0 1
6063 17253468 Physiotherapy treatment approaches for the recovery of postural control and lower limb function following stroke. 1 0 1
6041 25574904 Mailuoning for acute ischaemic stroke. 1 0 1
6042 17636655 Mannitol for acute stroke. 1 0 1
6043 29993119 Mirror therapy for improving motor function after stroke. 1 0 1
6044 26037617 Motivational interviewing for improving recovery after stroke. 1 0 1
6045 17443593 Naftidrofuryl for acute stroke. 1 0 1
6046 28429459 Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke. 1 0 1
6047 21975778 Non-pharmacological interventions for caregivers of stroke survivors. 1 0 1
6048 28721691 Occupational therapy for adults with problems in activities of daily living after stroke. 1 0 1
6049 23740541 Occupational therapy for care home residents with stroke. 1 0 1
6064 22972044 Piracetam for acute ischaemic stroke. 1 0 1
6050 20824849 Occupational therapy for cognitive impairment in stroke patients. 1 0 1
6083 24338496 Telerehabilitation services for stroke. 1 0 1
6082 30376602 Swallowing therapy for dysphagia in acute and subacute stroke. 1 0 1
6081 22258954 Surgical decompression for cerebral oedema in acute ischaemic stroke. 2 0 1
6069 28644548 Repetitive peripheral magnetic stimulation for activities of daily living and functional ability in people after stroke. 1 0 1
6005 21901674 Corticosteroids for acute ischaemic stroke. 2 0 1
6006 17443544 Dan Shen agents for acute ischaemic stroke. 1 0 1
5997 23728639 Cognitive rehabilitation for attention deficits following stroke. 1 0 1
5984 29355906 Antibiotic therapy for preventing infections in people with acute stroke. 1 0 1
6038 19588332 Interventions in the management of serum lipids for preventing stroke recurrence. 1 0 1
6040 19821415 Magnetic resonance imaging versus computed tomography for detection of acute vascular lesions in patients presenting with stroke symptoms. 1 0 1
6067 30129656 Recanalisation therapies for wake-up stroke. 1 0 1
6068 24567028 Rehabilitation for improving automobile driving after stroke. 1 0 1
6070 27841442 Repetitive task training for improving functional ability after stroke. 1 0 1
6080 20464736 Stroke liaison workers for stroke patients and carers: an individual patient data meta-analysis. 1 0 1
6071 23728683 Repetitive transcranial magnetic stimulation for improving function after stroke. 1 0 1
6072 18843711 Sanchi for acute ischaemic stroke. 1 0 1
6073 23152272 Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. 1 0 1
6075 22972045 Services for reducing duration of hospital care for acute stroke patients. 1 0 1
6076 20393947 Simultaneous bilateral training for improving arm function after stroke. 1 0 1
6066 26891451 Puerarin for ischaemic stroke. 1 0 1
6077 23076946 Sonothrombolysis for acute ischaemic stroke. 1 0 1
6079 20824857 Stem cell transplantation for ischemic stroke. 1 0 1
6610 26624987 Zuclopenthixol versus placebo for schizophrenia. 1 0 1
6609 20927748 Zotepine versus other atypical antipsychotics for schizophrenia. 1 0 1
6608 19821380 Ziprasidone versus other atypical antipsychotics for schizophrenia. 1 0 1
6586 12535453 Outcome measures and needs assessment tools for schizophrenia and related disorders. 1 0 1
6538 23152208 Bromperidol decanoate (depot) for schizophrenia. 1 0 1
6539 17253586 Cessation of medication for people with schizophrenia already stable on chlorpromazine. 1 0 1
6540 28940256 Chlorpromazine versus penfluridol for schizophrenia. 1 0 1
6541 27124109 Chlorpromazine versus reserpine for schizophrenia. 1 0 1
6542 19588385 Clozapine combined with different antipsychotic drugs for treatment resistant schizophrenia. 1 0 1
6544 15495000 Cognitive behaviour therapy for schizophrenia. 1 0 1
6545 22513966 Cognitive behaviour therapy versus other psychosocial treatments for schizophrenia. 1 0 1
6546 30572373 Cognitive behavioural therapy plus standard care versus standard care for people with schizophrenia. 1 0 1
6562 27370402 Fluphenazine (oral) versus atypical antipsychotics for schizophrenia. 1 0 1
6548 16856009 Compliance therapy for schizophrenia. 1 0 1
6550 19821303 Day hospital versus outpatient care for people with schizophrenia. 1 0 1
6551 15266450 Depot bromperidol decanoate for schizophrenia. 1 0 1
6552 15674872 Depot fluphenazine decanoate and enanthate for schizophrenia. 1 0 1
6553 17253464 Depot fluspirilene for schizophrenia. 1 0 1
6554 16034865 Depot perphenazine decanoate and enanthate for schizophrenia. 1 0 1
6555 15495016 Depot pipotiazine palmitate and undecylenate for schizophrenia. 1 0 1
6556 15674963 Distraction techniques for schizophrenia. 1 0 1
6558 30888709 Electroconvulsive therapy for treatment-resistant schizophrenia. 1 0 1
6560 24915451 Flupenthixol decanoate (depot) for schizophrenia or other similar psychotic disorders. 1 0 1
6537 18843722 Benzodiazepines for catatonia in people with schizophrenia and other serious mental illnesses. 1 0 1
6561 23152280 Flupenthixol versus placebo for schizophrenia. 1 0 1
6563 29893410 Fluphenazine (oral) versus placebo for schizophrenia. 1 0 1
6576 17253473 Molindone for schizophrenia and severe mental illness. 1 0 1
6568 17943812 Hypnosis for schizophrenia. 1 0 1
6569 29750432 Increasing antipsychotic dose for non response in schizophrenia. 1 0 1
6570 29749607 Increasing antipsychotic dose versus switching antipsychotic for non response in schizophrenia. 1 0 1
6571 17253540 Interventions to reduce weight gain in schizophrenia. 1 0 1
6572 17054266 Lamotrigine for schizophrenia. 1 0 1
6573 20927765 Levomepromazine for schizophrenia. 1 0 1
6564 16625590 Glutamatergic drugs for schizophrenia. 1 0 1
6574 26509923 Lithium for schizophrenia. 1 0 1
6577 19821433 Monetary incentives for schizophrenia. 1 0 1
6585 17253589 Oral fluphenazine versus placebo for schizophrenia. 1 0 1
6578 17253588 Morita therapy for schizophrenia. 1 0 1
6579 17253587 Mother and baby units for schizophrenia. 1 0 1
6580 28553702 Music therapy for people with schizophrenia and schizophrenia-like disorders. 1 0 1
6581 15846692 Music therapy for schizophrenia or schizophrenia-like illnesses. 1 0 1
6582 14584012 New generation antipsychotics for first episode schizophrenia. 1 0 1
6583 16437497 Nicotine for schizophrenia. 1 0 1
6584 15846619 Olanzapine for schizophrenia. 1 0 1
6575 17943763 Loxapine for schizophrenia. 1 0 1
6549 24092546 Dance therapy for schizophrenia. 1 0 1
6587 30946482 Peer support for people with schizophrenia or other serious mental illness. 1 0 1
6607 26488850 Yoga versus standard care for schizophrenia. 1 0 1
6588 16625563 Penfluridol for schizophrenia. 1 0 1
6612 15106174 Intra-pleural fibrinolytic therapy versus conservative management in the treatment of parapneumonic effusions and empyema. 1 0 1
6611 18425881 Intra-pleural fibrinolytic therapy versus conservative management in the treatment of adult parapneumonic effusions and empyema. 1 0 1
6589 24825770 Pericyazine for schizophrenia. 1 0 1
6590 17443621 Problem solving skills for schizophrenia. 1 0 1
6591 21678337 Psychoeducation for schizophrenia. 1 0 1
6592 24249315 Quetiapine versus other atypical antipsychotics for schizophrenia. 1 0 1
6593 19821422 Risperidone dose for schizophrenia. 1 0 1
6594 27977041 Risperidone versus placebo for schizophrenia. 1 0 1
6595 26059249 Social skills programmes for schizophrenia. 1 0 1
6596 20091661 Sulpiride augmentation for schizophrenia. 1 0 1
6597 24729184 Sulpiride versus placebo for schizophrenia. 1 0 1
6598 25871462 Supportive therapy for schizophrenia. 1 0 1
6599 17636691 Thioridazine for schizophrenia. 1 0 1
6601 25411556 Transcranial magnetic stimulation for schizophrenia. 1 0 1
6602 14974020 Trifluoperazine for schizophrenia. 1 0 1
6603 24414883 Trifluoperazine versus placebo for schizophrenia. 1 0 1
6604 19370601 Twenty-four hour care for schizophrenia. 1 0 1
6605 27884042 Valproate for schizophrenia. 1 0 1
6606 28960019 Yoga as part of a package of care versus standard care for schizophrenia. 1 0 1
6613 10908554 Intra-pleural fibrinolytic therapy vs. conservative management in the treatment of parapneumonic effusions and empyema. 1 0 1
6626 22071843 Mechanical dilatation of the cervix at non-labour caesarean section for reducing postoperative morbidity. 1 0 1
6636 30016540 Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections. 1 0 1
6624 15495078 Fetal pulse oximetry for fetal assessment in labour. 1 0 1
6615 12137614 Antibiotic prophylaxis for cesarean section. 1 0 1
6616 29096053 Antibiotic prophylaxis for episiotomy repair following vaginal birth. 1 0 1
6617 28779515 Antibiotic prophylaxis for operative vaginal delivery. 1 0 1
6618 10796247 Antibiotic prophylaxis regimens and drugs for cesarean section. 1 0 1
6619 12137684 Antibiotic regimens for management of intraamniotic infection. 1 0 1
6621 14583915 Closure versus non-closure of the peritoneum at caesarean section. 1 0 1
6622 25402227 Different classes of antibiotics given to women routinely for preventing infection at caesarean section. 1 0 1
6623 16235405 Efficacy and safety of cesarean delivery for prevention of mother-to-child transmission of HIV-1. 1 0 1
6614 20091536 Surgical sealant for preventing air leaks after pulmonary resections in patients with lung cancer. 2 0 1
6635 26827159 Techniques for assisting difficult delivery at caesarean section. 1 0 1
6625 10796147 Manual removal of placenta at caesarean section. 1 0 1
6627 30096215 Mechanical dilatation of the cervix during elective caeserean section before the onset of labour for reducing postoperative morbidity. 1 0 1
6628 18646109 Methods of delivering the placenta at caesarean section. 1 0 1
6630 23076903 Regional versus general anaesthesia for caesarean section. 1 0 1
6631 27314174 Routes of administration of antibiotic prophylaxis for preventing infection after caesarean section. 1 0 1
6632 29190037 Routine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity. 1 0 1
6633 10796177 Single versus two layer suturing for closing the uterine incision at caesarean section. 1 0 1
6634 30346040 Skin preparation for preventing infection following caesarean section. 1 0 1
6357 20824848 Octreotide for the treatment of chylothorax in neonates. 1 0 1
6355 30746700 Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders. 1 0 1
5020 30264852 Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants. 1 0 1
5405 26436598 High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma. 1 0 1
5407 14974035 Antibiotics for preventing infection in open limb fractures. 1 0 1
5398 26758576 Intensive versus conventional glycaemic control for treating diabetic foot ulcers. 2 0 1
5408 24014191 Antibiotics for treating chronic osteomyelitis in adults. 1 0 1
5410 24991723 Inhaled nitric oxide for the postoperative management of pulmonary hypertension in infants and children with congenital heart disease. 3 0 1
5411 23633336 Monoclonal antibody for reducing the risk of respiratory syncytial virus infection in children. 1 0 1
5412 24163137 Psychological interventions for depression in adolescent and adult congenital heart disease. 1 0 1
5413 11869662 Non surgical interventions for late radiation proctitis in patients who have received radical radiotherapy to the pelvis. 1 0 1
5414 30560568 Acupuncture for symptomatic gastroparesis. 1 0 1
5416 21678331 Adjuvant progestagens for endometrial cancer. 2 0 1
5418 21154390 Hormonal therapy in advanced or recurrent endometrial cancer. 1 0 1
5419 28968482 Lymphadenectomy for the management of endometrial cancer. 2 0 1
5420 10796737 Progestagens for endometrial cancer. 1 0 1
5409 23543532 Antibiotics for brain abscesses in people with cyanotic congenital heart disease. 1 0 1
5397 27701752 Immunotherapy for IgM anti-myelin-associated glycoprotein paraprotein-associated peripheral neuropathies. 1 0 1
5395 15495069 Exercise for people with peripheral neuropathy. 1 0 1
5394 11869620 Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy. 1 0 1
5371 15846602 Cyclosporine for induction of remission in Crohn's disease. 2 0 1
5372 16034910 Interventions for growth failure in childhood Crohn's disease. 2 0 1
5373 24558033 Low dose naltrexone for induction of remission in Crohn's disease. 1 0 1
5406 28429876 Iodine-131-meta-iodobenzylguanidine therapy for patients with newly diagnosed high-risk neuroblastoma. 1 0 1
5404 29975402 Different infusion durations for preventing platinum-induced hearing loss in children with cancer. 2 0 1
5327 15106167 Curative surgery for obstruction from primary left colorectal carcinoma: primary or staged resection? 2 0 1
5403 26417712 123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma. 1 0 1
5341 16235279 Non-nutritive sucking for promoting physiologic stability and nutrition in preterm infants. 1 0 1
5329 26202783 Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin, and school performance. 1 0 1
5331 19588318 Early trophic feeding for very low birth weight infants. 1 0 1
5332 23543508 Early trophic feeding versus enteral fasting for very preterm or very low birth weight infants. 1 0 1
5333 17943882 Effect of taurine supplementation on growth and development in preterm or low birth weight infants. 1 0 1
5334 26853855 Glutamine for induction of remission in Crohn's disease. 3 0 1
5335 16437478 Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants. 2 0 1
5336 26262909 Interventions for leg cramps in pregnancy. 1 0 1
5337 19821389 Interventions for prevention of post-operative recurrence of Crohn's disease. 2 0 1
5338 23543535 Lactase treated feeds to promote growth and feeding tolerance in preterm infants. 1 0 1
5339 20166096 Laparoscopic versus open surgery in small bowel obstruction. 1 0 1
5330 17943740 Deworming drugs for treating soil-transmitted intestinal worms in children: effects on growth and school performance. 1 0 1
5368 11279777 Budesonide for maintenance of remission in Crohn's disease. 1 0 1
5369 11686956 Corticosteroids for maintaining remission of Crohn's disease. 2 0 1
5370 14583917 Corticosteroids for maintenance of remission in Crohn's disease. 2 0 1
5399 28518221 Micronutrient supplementation in adults with HIV infection. 2 0 1
5400 23450580 Oral H1 antihistamines as monotherapy for eczema. 1 0 1
5401 10796564 Vaccines for preventing anthrax. 1 0 1
5402 17943790 Calcium channel blockers for preventing acute tubular necrosis in kidney transplant recipients. 1 0 1
5374 17253580 Natalizumab for induction of remission in Crohn's disease. 2 0 1
5375 24282062 Nutritional interventions for reducing gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy. 1 0 1
5376 24585498 Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease. 3 0 1
5377 21249709 Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease. 2 0 1
5247 25218725 Vaginal chlorhexidine during labour for preventing maternal and neonatal infections (excluding Group B Streptococcal and HIV). 2 0 1
5248 16855973 Aerosolized diuretics for preterm infants with (or developing) chronic lung disease. 2 0 1
5249 26998583 Antithrombin for the prevention of intraventricular hemorrhage in very preterm infants. 2 0 1
5250 11687053 Bronchodilators for the prevention and treatment of chronic lung disease in preterm infants. 2 0 1
5251 11869608 Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. 2 0 1
5242 19821304 Intravenous oxytocin alone for cervical ripening and induction of labour. 1 0 1
5252 20614468 Flow-cycled versus time-cycled synchronized ventilation for neonates. 2 0 1
5254 10796658 Immunoglobulin for preventing respiratory syncytial virus infection. 3 0 1
5255 16856077 Increased energy intake for preterm infants with (or developing) bronchopulmonary dysplasia/ chronic lung disease. 2 0 1
5256 10908553 Inhaled steroids for neonatal chronic lung disease. 2 0 1
5257 23821390 Intravenous immunoglobulin for preventing infection in preterm and/or low birth weight infants. 2 0 1
5258 14973955 Intravenous immunoglobulin for preventing infection in preterm and/or low-birth-weight infants. 2 0 1
5259 11034718 Intravenous or enteral loop diuretics for preterm infants with (or developing) chronic lung disease. 2 0 1
5260 28836266 Late (≥ 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants. 2 0 1
5261 29125893 Mesenchymal stem cells for the prevention and treatment of bronchopulmonary dysplasia in preterm infants. 2 0 1
5262 24218013 Prostaglandins before caesarean section for preventing neonatal respiratory distress. 3 0 1
5253 21735414 Fluid restriction and prophylactic indomethacin versus prophylactic indomethacin alone for prevention of morbidity and mortality in extremely low birth weight infants. 2 0 1
5263 29256573 Bilateral versus unilateral hearing aids for bilateral hearing impairment in adults. 2 0 1
5241 23853046 High-dose versus low-dose oxytocin for augmentation of delayed labour. 1 0 1
5246 24578236 Tocolytics for preterm premature rupture of membranes. 1 0 1
5245 10796161 Prostaglandins versus oxytocin for prelabour rupture of membranes at term. 2 0 1
5244 10796160 Prostaglandins versus oxytocin for prelabour rupture of membranes at or near term. 2 0 1
5388 26337716 Interventions for the treatment of metastatic extradural spinal cord compression in adults. 2 0 1
5378 22786523 Osmotic and stimulant laxatives for the management of childhood constipation. 1 0 1
5379 18646162 Probiotics for induction of remission in Crohn's disease. 2 0 1
5380 30883665 Psychological interventions for parents of children and adolescents with chronic illness. 1 0 1
5381 21328288 Psychological interventions for treatment of inflammatory bowel disease. 1 0 1
5382 18425970 Traditional corticosteroids for induction of remission in Crohn's disease. 2 0 1
5383 18646167 Type I interferons for induction of remission in ulcerative colitis. 1 0 1
5386 25504522 Glutamine supplementation for young infants with severe gastrointestinal disease. 1 0 1
5387 21563133 Primary groin irradiation versus primary groin surgery for early vulvar cancer. 1 0 1
5389 17443532 Rehabilitation interventions for foot drop in neuromuscular disease. 1 0 1
5243 24729384 Planned home versus hospital care for preterm prelabour rupture of the membranes (PPROM) prior to 37 weeks' gestation. 1 0 1
5390 21249667 Single or double-level anterior interbody fusion techniques for cervical degenerative disc disease. 2 0 1
5391 22972118 Total disc replacement for chronic back pain in the presence of disc degeneration. 1 0 1
5392 10796870 Aldose reductase inhibitors for the prevention and treatment of diabetic peripheral neuropathy. 1 0 1
5393 24096743 Chinese herbal medicine for diabetic peripheral neuropathy. 1 0 1
5319 26068957 Steroid-eluting sinus stents for improving symptoms in chronic rhinosinusitis patients undergoing functional endoscopic sinus surgery. 1 0 1
5422 30488948 Sliding scale insulin for non-critically ill hospitalised adults with diabetes mellitus. 2 0 1
5318 20614444 Statins for children with familial hypercholesterolemia. 1 0 1
5316 29974450 Remote ischaemic conditioning for preventing and treating ischaemic stroke. 2 0 1
5328 23152203 Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin and school performance. 1 0 1
5326 12519610 Celecoxib for rheumatoid arthritis. 1 0 1
6354 25914906 Chinese herbal medicines for hypothyroidism. 1 0 1
5094 23440785 Ginkgo biloba extract for age-related macular degeneration. 2 0 1
5098 17636693 Photodynamic therapy for neovascular age-related macular degeneration. 1 0 1
5099 29664159 Reading aids for adults with low vision. 2 0 1
5100 23440797 Surgical implantation of steroids with antiangiogenic characteristics for treating neovascular age-related macular degeneration. 1 0 1
5103 29352477 Benzodiazepines for antipsychotic-induced tardive dyskinesia. 2 0 1
5104 29578611 Calcium channel blockers for antipsychotic-induced tardive dyskinesia. 2 0 1
5105 22071797 Calcium channel blockers for neuroleptic-induced tardive dyskinesia. 2 0 1
5092 12076389 Antioxidant vitamin and mineral supplements for age-related macular degeneration. 1 0 1
5079 21563145 Prophylactic corticosteroids for cardiopulmonary bypass in adults. 1 0 1
5078 22419321 Off-pump versus on-pump coronary artery bypass grafting for ischaemic heart disease. 1 0 1
5077 28394022 Limited versus full sternotomy for aortic valve replacement. 1 0 1
5055 23450572 Adjuvant radiotherapy and/or chemotherapy after surgery for uterine carcinosarcoma. 1 0 1
5057 11406030 Intravenous immunoglobulin for Guillain-Barré syndrome. 1 0 1
5058 23235588 Intravenous immunoglobulin for myasthenia gravis. 2 0 1
5059 12519572 Plasma exchange for myasthenia gravis. 2 0 1
5060 18646146 Radioiodine treatment for pediatric Graves' disease. 3 0 1
5061 22513970 Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. 1 0 1
5062 16437515 Uterine artery embolization for symptomatic uterine fibroids. 1 0 1
5063 30595004 Transperitoneal versus retroperitoneal laparoscopic adrenalectomy for adrenal tumours in adults. 1 0 1
5064 15106146 Anticoagulants for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischaemic attack. 1 0 1
5095 29847689 Implantable miniature telescope (IMT) for vision loss due to end-stage age-related macular degeneration. 1 0 1
5093 24431152 Complement inhibitors for age-related macular degeneration. 1 0 1
5325 16437456 Antidepressants for depressed elderly. 1 0 1
5091 10796707 Antioxidant vitamin and mineral supplementation for preventing age-related macular degeneration. 1 0 1
5021 29041034 Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates. 3 0 1
5022 22592683 Inhaled versus systemic corticosteroids for preventing chronic lung disease in ventilated very low birth weight preterm neonates. 1 0 1
5023 10796168 Intravenous indomethacin for preventing mortality and morbidity in very low birth weight infants. 2 0 1
5024 17253569 Postnatal thyroid hormones for respiratory distress syndrome in preterm infants. 1 0 1
5026 25473815 Restricted versus liberal water intake for preventing morbidity and mortality in preterm infants. 3 0 1
5016 11686979 Furosemide for symptomatic patent ductus arteriosus in indomethacin-treated infants. 1 0 1
5052 26295202 Prophylactic lidocaine for myocardial infarction. 4 0 1
5053 21901717 Psychological and pharmacological interventions for depression in patients with coronary artery disease. 1 0 1
5054 21249663 Statins for the primary prevention of cardiovascular disease. 1 0 1
5082 17054289 Haemodiafiltration, haemofiltration and haemodialysis for end-stage kidney disease. 1 0 1
5083 30338514 Interventions for reducing inflammation in familial Mediterranean fever. 2 0 1
5084 19821441 Amifostine for salivary glands in high-dose radioactive iodine treated differentiated thyroid cancer. 1 0 1
5085 21069705 Recombinant human thyrotropin (rhTSH) aided radioiodine treatment for residual or metastatic differentiated thyroid cancer. 2 0 1
5086 29938789 Antibiotics for exacerbations of asthma. 2 0 1
5087 12917970 Anticholinergic therapy for chronic asthma in children over two years of age. 1 0 1
5088 23235599 Inhaled magnesium sulfate in the treatment of acute asthma. 1 0 1
5089 30834517 Anti-vascular endothelial growth factor for neovascular age-related macular degeneration. 2 0 1
5090 18425911 Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration. 2 0 1
5081 19588398 Chinese herbal medicine for endometriosis. 1 0 1
5065 11279741 Anticoagulants or antiplatelet therapy for non-rheumatic atrial fibrillation and flutter. 1 0 1
5066 23839768 Antiplatelet and anticoagulation for patients with prosthetic heart valves. 1 0 1
5067 22513945 Catheter ablation for paroxysmal and persistent atrial fibrillation. 1 0 1
5068 24677203 Direct thrombin inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in people with non-valvular atrial fibrillation. 1 0 1
5354 10796562 Steroids for treating cerebral malaria. 2 0 1
5357 16034849 Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis. 1 0 1
5358 15846703 Electrotherapy for neck disorders. 1 0 1
5359 26397370 Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment. 1 0 1
5360 20091561 Manipulation or mobilisation for neck pain. 1 0 1
5361 28090192 Spinal rehabilitative exercise or manual treatment for the prevention of cervicogenic headache in adults. 1 0 1
5362 18843716 Acupuncture for restless legs syndrome. 2 0 1
5364 10796524 Anti-tuberculous therapy for maintaining remission of Crohn's disease. 2 0 1
5365 10796482 Azathioprine for maintaining remission of Crohn's disease. 2 0 1
5366 20556747 Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease. 2 0 1
5355 11869593 Support for breastfeeding mothers. 1 0 1
5367 19160175 Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease. 1 0 1
5342 15266441 Non-steroidal anti-inflammatory drugs for preventing heterotopic bone formation after hip arthroplasty. 1 0 1
5340 27699765 Non-nutritive sucking for increasing physiologic stability and nutrition in preterm infants. 1 0 1
5320 24307487 Treatment of hypertension in peripheral arterial disease. 2 0 1
5321 25198150 Vaginal dilator therapy for women receiving pelvic radiotherapy. 1 0 1
5322 17054235 Alpha-glucosidase inhibitors for people with impaired glucose tolerance or impaired fasting blood glucose. 1 0 1
5323 10796537 Anthelmintic drugs for treating worms in children: effects on growth and cognitive performance. 1 0 1
5324 22895960 Antibiotic regimens for the empirical treatment of newborn infants with necrotising enterocolitis. 1 0 1
5343 27111831 Non-surgical interventions for late rectal problems (proctopathy) of radiotherapy in people who have received radiotherapy to the pelvis. 2 0 1
5353 27801499 Six-month therapy for abdominal tuberculosis. 2 0 1
5352 17054276 Rimonabant for overweight or obesity. 2 0 1
5212 24442917 Helminth therapy (worms) for induction of remission in inflammatory bowel disease. 5 0 1
5069 28378924 Educational and behavioural interventions for anticoagulant therapy in patients with atrial fibrillation. 1 0 1
5070 23633374 Effectiveness of systematic screening for the detection of atrial fibrillation. 1 0 1
5071 27871122 Efficacy and safety of ablation for people with non-paroxysmal atrial fibrillation. 1 0 1
5072 16034878 Electrical cardioversion for atrial fibrillation and flutter. 1 0 1
5073 28181684 Exercise-based cardiac rehabilitation for adults with atrial fibrillation. 1 0 1
5074 29509959 Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation. 1 0 1
5075 24156099 Factor Xa inhibitors: a step forward in the treatment of atrial fibrillation? 1 0 1
5076 23440790 Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery. 1 0 1
5213 19160337 Humanized antibody to the alpha4beta7 integrin for induction of remission in ulcerative colitis. 3 0 1
5351 21069683 Recombinant human interleukin 10 for induction of remission in Crohn's disease. 2 0 1
5214 17636844 Omega 3 fatty acids (fish oil) for maintenance of remission in ulcerative colitis. 2 0 1
5215 10796555 Oral 5-aminosalicylic acid for inducing remission in ulcerative colitis. 2 0 1
5344 10796661 Oral pentoxifylline for treatment of venous leg ulcers. 1 0 1
5346 16437447 Oral xanthines as maintenance treatment for asthma in children. 2 0 1
5347 23828487 Peritoneal closure versus no peritoneal closure for patients undergoing non-obstetric abdominal operations. 1 0 1
5348 21678354 Peritoneal drainage versus laparotomy as initial surgical treatment for perforated necrotizing enterocolitis or spontaneous intestinal perforation in preterm low birth weight infants. 1 0 1
5349 17636780 Prophylactic nasogastric decompression after abdominal surgery. 1 0 1
5350 26111021 Propofol versus thiopental sodium for the treatment of refractory status epilepticus. 1 0 1
5239 30125998 Discontinuation of intravenous oxytocin in the active phase of induced labour. 1 0 1
5217 10796556 Oral 5-aminosalicylic acid for maintaining remission in ulcerative colitis. 3 0 1
5218 28886205 Placebo response and remission rates in randomised trials of induction and maintenance therapy for ulcerative colitis. 2 0 1
6447 16235323 Bed rest with or without hospitalisation for hypertension during pregnancy. 1 0 1
6449 18843651 Blood pressure lowering efficacy of angiotensin converting enzyme (ACE) inhibitors for primary hypertension. 1 0 1
6439 25354543 Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child. 1 0 1
6428 21249705 Strategies for improving adherence to antiepileptic drug treatment in patients with epilepsy. 1 0 1
6481 24343836 Agomelatine versus other antidepressive agents for major depression. 1 0 1
6483 24353997 Fluoxetine versus other types of pharmacotherapy for depression. 1 0 1
6511 23235638 Decompressive surgery for treating nerve damage in leprosy. 1 0 1
6513 11406003 Antibiotic prophylaxis for mammalian bites. 2 0 1
6514 17054239 Acupuncture for treatment of irritable bowel syndrome. 1 0 1
6515 15495005 Antibiotic regimens for endometritis after delivery. 2 0 1
6516 10796324 Cholinergic medication for neuroleptic-induced tardive dyskinesia. 1 0 1
6517 16437519 Diacerein for osteoarthritis. 1 0 1
6518 22071808 Oral immunoglobulin for the prevention of rotavirus infection in low birth weight infants. 1 0 1
6519 21975740 Oral immunoglobulin for the treatment of rotavirus diarrhea in low birth weight infants. 1 0 1
6520 10908548 Prevention of chronic NSAID induced upper gastrointestinal toxicity. 1 0 1
6510 11034698 Corticosteroids for pulmonary sarcoidosis. 1 0 1
6521 12519573 Prevention of NSAID-induced gastroduodenal ulcers. 1 0 1
6523 22696367 Azithromycin versus penicillin G benzathine for early syphilis. 1 0 1
6524 22258978 Acetylcholinesterase inhibitors for schizophrenia. 1 0 1
6525 20091599 Amisulpride versus other atypical antipsychotics for schizophrenia. 1 0 1
6448 22895943 Blood pressure lowering efficacy of alpha blockers for primary hypertension. 1 0 1
6446 25148386 Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension. 1 0 1
5219 17943867 Probiotics for induction of remission in ulcerative colitis. 3 0 1
6445 30480757 Acupuncture for hypertension. 1 0 1
6466 16625609 Calcium supplementation for the management of primary hypertension in adults. 1 0 1
6480 22696374 Tianma Gouteng Yin Formula for treating primary hypertension. 1 0 1
6452 20091622 Blood pressure lowering efficacy of beta-blockers as second-line therapy for primary hypertension. 1 0 1
6450 18843650 Blood pressure lowering efficacy of angiotensin receptor blockers for primary hypertension. 1 0 1
6429 28157274 Strategies for improving adherence to antiepileptic drug treatment in people with epilepsy. 1 0 1
6430 30383287 Subpial transection surgery for epilepsy. 1 0 1
6431 28981957 The role of high-frequency oscillations in epilepsy surgery planning. 1 0 1
6432 17253477 Therapeutic monitoring of antiepileptic drugs for epilepsy. 1 0 1
6433 24500879 Tiagabine add-on for drug-resistant partial epilepsy. 1 0 1
6434 24570033 Topiramate add-on for drug-resistant partial epilepsy. 1 0 1
6435 10796787 Topiramate for drug-resistant partial epilepsy. 1 0 1
6436 27922722 Topiramate versus carbamazepine monotherapy for epilepsy: an individual participant data review. 1 0 1
6437 19588391 Traditional Chinese medicine for epilepsy. 1 0 1
6451 26961574 Blood pressure lowering efficacy of beta-1 selective beta blockers for primary hypertension. 1 0 1
6438 27513825 Transcranial magnetic stimulation for the treatment of epilepsy. 1 0 1
6440 23440814 Vigabatrin for refractory partial epilepsy. 1 0 1
6441 26580100 Vigabatrin versus carbamazepine monotherapy for epilepsy. 1 0 1
6443 24353187 Zonisamide add-on for drug-resistant partial epilepsy. 1 0 1
6444 10796786 Zonisamide for drug-resistant partial epilepsy. 1 0 1
6526 15495131 Amphetamines for schizophrenia. 1 0 1
6527 24353163 Anticholinergic medication for non-clozapine neuroleptic-induced hypersalivation in people with schizophrenia. 1 0 1
6528 28658515 Antipsychotic combinations for schizophrenia. 1 0 1
6529 22336800 Antipsychotic drug treatment for elderly people with late-onset schizophrenia. 1 0 1
6502 15674961 Transabdominal pre-peritoneal (TAPP) vs totally extraperitoneal (TEP) laparoscopic techniques for inguinal hernia repair. 1 0 1
6503 22258939 Amnioinfusion for potential or suspected umbilical cord compression in labour. 2 0 1
6504 18646160 Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome. 1 0 1
6505 23076936 Cyclo-oxygenase (COX) inhibitors for preventing preterm labour. 1 0 1
6496 30703272 Exercise for preventing falls in older people living in the community. 1 0 1
6427 17443554 Self-management education for children with epilepsy. 1 0 1
6426 17443553 Self-management education for adults with epilepsy. 1 0 1
6425 12519561 Remacemide for drug-resistant localization related epilepsy. 1 0 1
6342 11279717 Interventions to improve the management of diabetes mellitus in primary care, outpatient and community settings. 1 0 1
6343 19160276 Low glycaemic index, or low glycaemic load, diets for diabetes mellitus. 1 0 1
6344 30328611 Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus. 1 0 1
6345 23235661 Psychological and pharmacological interventions for depression in patients with diabetes mellitus and depression. 1 0 1
6346 16625575 Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus. 1 0 1
6348 26891370 Radioiodine therapy versus antithyroid medications for Graves' disease. 3 0 1
6349 23728689 Rituximab for thyroid-associated ophthalmopathy. 1 0 1
6350 20091544 Antithyroid drug regimen for treating Graves' hyperthyroidism. 2 0 1
6351 17443591 Chinese herbal medicines for hyperthyroidism. 1 0 1
6341 15266506 Inhaled insulin in diabetes mellitus. 1 0 1
6352 28260263 Iodine supplementation for women during the preconception, pregnancy and postpartum period. 2 0 1
6501 22513902 Shouldice technique versus other open techniques for inguinal hernia repair. 1 0 1
6500 22786511 Open Preperitoneal Techniques versus Lichtenstein Repair for elective Inguinal Hernias. 1 0 1
6499 12519568 Open mesh versus non-mesh for repair of femoral and inguinal hernia. 1 0 1
6488 21154393 Second-generation antipsychotics for major depressive disorder and dysthymia. 1 0 1
6530 21678355 Antipsychotic medication for early episode schizophrenia. 1 0 1
6531 16437531 Antipsychotic medication for elderly people with schizophrenia. 1 0 1
6522 29257353 Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. 1 0 1
6482 19370639 Escitalopram versus other antidepressive agents for depression. 1 0 1
6509 18425933 Reconstructive techniques after rectal resection for rectal cancer. 1 0 1
6507 22972040 Prophylactic versus therapeutic amnioinfusion for oligohydramnios in labour. 2 0 1
6485 26395901 Ketamine and other glutamate receptor modulators for depression in adults. 1 0 1
6487 25267892 Paroxetine versus other anti-depressive agents for depression. 1 0 1
6489 25267891 Venlafaxine versus other anti-depressive agents for depression. 1 0 1
6498 28170080 Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty. 1 0 1
6490 14583928 Allergen immunotherapy for asthma. 1 0 1
6491 11686981 House dust mite control measures for asthma. 1 0 1
6492 12535446 Pet allergen control measures for allergic asthma in children and adults. 1 0 1
6493 12804442 Sublingual immunotherapy for allergic rhinitis. 1 0 1
6494 23076950 Venom immunotherapy for preventing allergic reactions to insect stings. 1 0 1
6508 23913522 Transabdominal amnioinfusion for improving fetal outcomes after oligohydramnios secondary to preterm prelabour rupture of membranes before 26 weeks. 1 0 1
6495 24258195 Clinical assessment to screen for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults. 1 0 1
6497 12535413 Laparoscopic techniques versus open techniques for inguinal hernia repair. 1 0 1
6479 20091658 Roselle for hypertension in adults. 1 0 1
6477 16856053 Potassium supplementation for the management of primary hypertension in adults. 1 0 1
6475 10908526 Pharmacotherapy for hypertension in women of different races. 1 0 1
5292 25569177 Parent-infant psychotherapy for improving parental and infant mental health. 1 0 1
5297 22513923 Treatment for mitochondrial disorders. 1 0 1
5298 26662716 Different treatment regimens of magnesium sulphate for tocolysis in women in preterm labour. 1 0 1
5299 24687190 Interventions for preventing neuropathy caused by cisplatin and related compounds. 1 0 1
5300 24249436 Catheter policies for management of long term voiding problems in adults with neurogenic bladder disorders. 1 0 1
5301 24859260 Surgical management of functional bladder outlet obstruction in adults with neurogenic bladder dysfunction. 3 0 1
5302 10796469 Angioplasty (versus non surgical management) for intermittent claudication. 2 0 1
5303 16856032 Angioplasty for intracranial artery stenosis. 1 0 1
5304 30536919 Angioplasty versus stenting for infrapopliteal arterial lesions in chronic limb-threatening ischaemia. 1 0 1
5295 26171898 Supplementation with long chain polyunsaturated fatty acids (LCPUFA) to breastfeeding mothers for improving child growth and development. 2 0 1
5305 24833157 Angioplasty versus stenting for subclavian artery stenosis. 1 0 1
5307 25478936 Balloon angioplasty, with and without stenting, versus medical therapy for hypertensive patients with renal artery stenosis. 2 0 1
5308 16235289 Carotid endarterectomy for asymptomatic carotid stenosis. 1 0 1
5309 28590505 Carotid endarterectomy for symptomatic carotid stenosis. 1 0 1
5310 25760812 Effectiveness of posterior decompression techniques compared with conventional laminectomy for lumbar stenosis. 1 0 1
5311 11406010 Erythromycin for feeding intolerance in preterm infants. 3 0 1
5312 14583992 Erythromycin for the prevention of chronic lung disease in intubated preterm infants at risk for, or colonized or infected with Ureaplasma urealyticum. 2 0 1
5313 29429146 Graft type for femoro-popliteal bypass surgery. 1 0 1
5314 12535485 Interventions for the physical aspects of sexual dysfunction in women following pelvic radiotherapy. 2 0 1
5315 21069695 Pain relief for outpatient hysteroscopy. 1 0 1
5296 22071834 Lasers or light sources for treating port-wine stains. 1 0 1
5268 12519546 Interventions for treating tuberculous pericarditis. 1 0 1
5267 19821308 Vasodilators and vasoactive substances for idiopathic sudden sensorineural hearing loss. 1 0 1
5229 20927749 Unfractionated or low-molecular weight heparin for induction of remission in ulcerative colitis. 2 0 1
5220 18254055 Probiotics for treatment of Clostridium difficile-associated colitis in adults. 2 0 1
5221 20091560 Rectal 5-aminosalicylic acid for induction of remission in ulcerative colitis. 2 0 1
5223 19821376 Specialist nursing interventions for inflammatory bowel disease. 4 0 1
5224 26393522 The impact of biological interventions for ulcerative colitis on health-related quality of life. 3 0 1
5225 25340915 Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease. 4 0 1
5226 15495126 Transdermal nicotine for induction of remission in ulcerative colitis. 3 0 1
5240 21975767 High dose versus low dose oxytocin for augmentation of delayed labour. 1 0 1
3657 10796635 Corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. 1 0 1
5230 25105240 Vedolizumab for induction and maintenance of remission in ulcerative colitis. 2 0 1
5265 23818120 Steroids for idiopathic sudden sensorineural hearing loss. 1 0 1
5232 24092529 Strategies for partner notification for sexually transmitted infections, including HIV. 4 0 1
5233 25812932 Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock. 2 0 1
5234 15846752 Primary stenting versus primary balloon angioplasty for treating acute myocardial infarction. 2 0 1
5235 12535496 Psychological therapies for the management of chronic and recurrent pain in children and adolescents. 1 0 1
5236 29106702 Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia. 1 0 1
5237 27208913 Induction of labour at or near term for suspected fetal macrosomia. 1 0 1
5238 17054263 Intrapartum interventions for preventing shoulder dystocia. 1 0 1
5228 26368001 Type I interferons for induction of remission in ulcerative colitis. 2 0 1
5306 12917908 Antiplatelet therapy for preventing stroke and other vascular events after carotid endarterectomy. 1 0 1
5291 27412362 Oral non-steroidal anti-inflammatory drugs (single dose) for perineal pain in the early postpartum period. 1 0 1
6474 12917933 Oral beta-blockers for mild to moderate hypertension during pregnancy. 1 0 1
5290 10796270 Oestrogens and progestogens for preventing and treating postnatal depression. 1 0 1
5002 15674873 Membrane sweeping for induction of labour. 1 0 1
5866 16235369 Local anesthetic sympathetic blockade for complex regional pain syndrome. 1 0 1
5868 19821330 Surgery for thumb (trapeziometacarpal joint) osteoarthritis. 1 0 1
6455 26306578 Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension. 1 0 1
6456 22895937 Blood pressure lowering efficacy of loop diuretics for primary hypertension. 1 0 1
6457 24585007 Blood pressure lowering efficacy of nonselective beta-blockers for primary hypertension. 1 0 1
6458 25427719 Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension. 1 0 1
6459 23152254 Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension. 1 0 1
6460 19821434 Blood pressure lowering efficacy of reserpine for primary hypertension. 1 0 1
6461 26000442 Blood pressure-lowering efficacy of loop diuretics for primary hypertension. 1 0 1
6462 24869750 Blood pressure-lowering efficacy of monotherapy with thiazide diuretics for primary hypertension. 1 0 1
6463 27997978 Blood pressure-lowering efficacy of reserpine for primary hypertension. 1 0 1
6453 26935713 Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. 1 0 1
6464 25922862 Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes. 1 0 1
6467 16856060 Combined calcium, magnesium and potassium supplementation for the management of primary hypertension in adults. 1 0 1
6468 10796721 Dieting to reduce body weight for controlling hypertension in adults. 1 0 1
6469 22513955 Fermented milk for hypertension. 1 0 1
6470 28084624 First-line combination therapy versus first-line monotherapy for primary hypertension. 1 0 1
6471 29667175 First-line drugs for hypertension. 1 0 1
5317 23771708 Routine intraoperative ureteric stenting for kidney transplant recipients. 1 0 1
5289 18843619 Oestrogens and progestins for preventing and treating postpartum depression. 1 0 1
5288 17636711 Individual or group antenatal education for childbirth or parenthood, or both. 1 0 1
5277 27647489 Plasma transfusions prior to insertion of central lines for people with abnormal coagulation. 1 0 1
5269 15495040 Mediastinal chest drain clearance for cardiac surgery. 1 0 1
5270 10796091 Antihistamines versus aspirin for itching in late pregnancy. 1 0 1
5271 22895942 Banding ligation versus beta-blockers for primary prevention in oesophageal varices in adults. 1 0 1
5272 26627708 Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia. 1 0 1
5273 23728692 Electro-coagulation for liver metastases. 2 0 1
5274 22419301 Human recombinant activated factor VII for upper gastrointestinal bleeding in patients with liver diseases. 1 0 1
5275 23728679 Percutaneous ethanol injection for liver metastases. 2 0 1
5276 30575956 Physical exercise for people with cirrhosis. 1 0 1
5278 16625556 S-adenosyl-L-methionine for alcoholic liver diseases. 1 0 1
5287 28681500 Continuous support for women during childbirth. 1 0 1
5279 23633373 Transarterial (chemo)embolisation versus no intervention or placebo intervention for liver metastases. 2 0 1
5280 10796693 Vaccines for preventing hepatitis B in health-care workers. 1 0 1
5281 26886473 Antibiotic use for irreversible pulpitis. 1 0 1
5282 29990391 Injectable local anaesthetic agents for dental anaesthesia. 1 0 1
5283 22972129 Irrigants for non-surgical root canal treatment in mature permanent teeth. 1 0 1
5284 15846711 Antidepressant prevention of postnatal depression. 1 0 1
5285 28181214 Aspirin (single dose) for perineal pain in the early postpartum period. 1 0 1
5286 11686971 Caregiver support for postpartum depression. 1 0 1
5817 26384035 Immunomodulators and immunosuppressants for relapsing-remitting multiple sclerosis: a network meta-analysis. 1 0 1